Detailed Mechanism Funding and Narrative

Years of mechanism: 2007 2008 2009

Details for Mechanism ID: 5460
Country/Region: Zambia
Year: 2008
Main Partner: Sanquin Blood Supply
Main Partner Program: Consulting Services
Organizational Type: Private Contractor
Funding Agency: HHS/CDC
Total Funding: $500,000

Funding for Biomedical Prevention: Blood Safety (HMBL): $500,000

The funding level for this activity in FY 2008 has increased since FY 2007. Narrative changes include

updates on progress made and expansion of activities.

This activity relates to ZNBTS (#9049). Sanquin has provided useful technical assistance, supervisory

quality support, and residential training for the Zambia National Blood Transfusion Service (ZNBTS) since

the inception of PEPFAR in Zambia. Sanquin will continue to support areas that enable the ZNBTS strategy

which includes improved quality assurance, development of blood products, donor recruitment, donor

retention, and expanded laboratory capacity. Lead experts from Sanquin provide routine support through

supervisory visits to Zambia to assist in troubleshooting and continued advice on scale-up and program

expansion. Support comes in the form of workshops and on-the-job training. An additional feature is to bring

ZNBTS staff to the Sanquin headquarters in the Netherlands for one month on-site residential training

focused on training-the-trainer and managerial aspects of operations. There, staff are able to gain practical

experience in quality assurance, management, donor services, laboratory supervision, and quality systems

for blood transfusion services.

In 2007, Sanquin designed and launched a Master's degree program in blood safety with the University of

Groningen in the Netherlands. The program will combine e-learning and on-site practical residencies.

Theory and basic information on blood safety will be provided via distance learning formats. Students will

then be required to spend a period of 4-6 months in the Netherlands working with Sanquin to develop

comprehensively practical management skills. In January 2007, two people from ZNBTS received

scholarships and enrolled into the program. By providing assistance to the ZNBTS in these key areas,

which includes human capacity strengthening, Sanquin will continue to significantly contribute to the overall

sustainability of the national blood service programs.

Also in December 2006, Sanquin provided technical and financial support toward the successful ZNBTS

stakeholders' meeting to launch a Bill designed to strengthen the Zambian legal and regulatory framework

for blood safety. Sanquin provided legal expertise to help draft the bill and also hosted Zambian officials in

the Netherlands to further learn about the process and importance of creating such a bill.

In the same year Sanquin advised on the redesigning of the process flows of the blood bank operations in

order to alter the Lusaka blood center building. With the designed alterations the building will be in

compliance with general accepted GMP and GLP guidelines.

In FY 2008, Sanquin will continue to provide valuable trainings for ZNBTS and hospital staff, namely training

to assist clinicians in areas such as the usage of blood components into cryoprecipitate, fresh frozen

plasma, platelets and packed red blood cells; supporting up to 115 sites. For that aim, the blood component

preparation activities of the blood bank need to be improved and expanded. Sanquin will actively advise in

setting-up Transfusion Committees in Zambian hospitals with an aim to improve for the clinical use of blood

products.

The Zambian legal and regulatory framework for blood safety , which began in 2006 needs to be finalized

and made effective. Sanquin will advise and guide in this context.

Furthermore Sanquin will advise in identifying suitable counterpart institutions, meetings, and workshops

that provide for knowledge sharing and continuous medical education for professional staff.

It is to be expected that a newly designed blood bank building in Kabwe will be constructed. Sanquin will

provide knowledge and advise as was provided for the Lusaka building.

Throughout all donor centers the use of barcodes will be introduced in order to improve safety of blood

collections, together with the introduction of electric mix weighing equipment (standardization).

Finally, the donor selection procedure will be improved by introducing general excepted techniques for the

measurement of hemoglobin concentrations in donors. Equipment, reagents and training of staff is needed

to meet these standards.

In general the ZNBTS is improving step-by-step the primary process of the blood bank. In the coming year's

introduction of computer networks and specialized programs need to be investigated (e.g. Laboratory

Information management Systems or LIMS and general blood bank software) and implemented. Sanquin

will advise and guide through the selection process and implementations.

Targets set for this activity cover a period ending September 30, 2009.