Detailed Mechanism Funding and Narrative

Years of mechanism: 2007 2008 2009

Details for Mechanism ID: 5280
Country/Region: Zambia
Year: 2008
Main Partner: American Society for Microbiology
Main Partner Program: NA
Organizational Type: Private Contractor
Funding Agency: HHS/CDC
Total Funding: $130,000

Funding for Laboratory Infrastructure (HLAB): $130,000

The funding level for this activity in FY 2008 will remain the same as in FY 2007. Only minor narrative

updates have been made to highlight progress and achievements.

This activity is related to CDC Lab TA.

Opportunistic Infections (OIs) are common in HIV populations and are a major threat to People Living with

HIV/AIDS (PLWHA) both prior to diagnosis and during care and treatment programs. Global efforts toward

detection of tuberculosis (TB) are currently in place, however basic microbiology laboratory services for

blood stream and other infections such as sexually transmitted diseases, which have high morbidity in the

HIV-infected patients, are limited and lack quality.

In FY 2007, this activity supported technical assistance from the American Society for Microbiology (ASM).

ASM technical experts provided support in the areas of TB and OIs. The technical experts conducted a

fluorescent smear TB microscopy workshop, provided gram staining training and proficiency testing, trained

on the function and maintenance of the BACTEC 9050, and also educated laboratory staff and medical

personnel on proper blood culture collection techniques. Training was also provided to laboratory staff,

clinicians, and pharmacists to evaluate the antibiotic formularies and laboratory testing panels to rationalize

their usage.

In FY 2008, the ASM will continue to provide in-country expertise for cost effective microbiology services

and expand support for detection of sexually transmitted diseases, infant HIV diagnosis by dried blood spot

(DBS) polymerase chain reaction (PCR) techniques, laboratory systems, strategic planning, standardization

of protocols for antibiotic utilization, infection control and good laboratory and clinical practice. ASM's major

emphasis area will continue to be human capacity development. Activities conducted will include training

on the most common bacterial infections and cost-effective diagnostic techniques, improvement in rapid TB

culture, identification and drug susceptibility testing at the National and Regional TB reference laboratories.

Other activities will include on-site training and consultation for development and standardization of

laboratory procedures, improving specimen management, correlation of laboratory results with patient

outcomes in other laboratory areas such as chemistry, hematology, and CD4 testing. Rapid cost effective

diagnostics to improve quality and human resource capacity in the laboratory will be implemented.

Technical experts will continue to provide support to the U.S. Government (USG) team, the Zambian

Ministry of Health (MoH) and the Zambian Ministry of Defense (MOD). Additionally, ASM will work with

cooperating laboratory partners (such as JHPIEGO and the naval defense medical team) to strengthen

microbiology services and treatment of OIs. Integration and co-ordination of the teams involved will improve

the monitoring and utilization of diagnostic services for OI's and STI's.

The technical experts provide in-country technical assistance for periods between three to four weeks and

return for multiple consultations. This activity provides support for their travel and other costs related to

their consultancy to the National Laboratory QA Program in Zambia. Trainings will be done in consultation

with CDC-Zambia or other organizations. Target data is collected and incorporated with the CDC Lab TA

activity.