Detailed Mechanism Funding and Narrative

Years of mechanism: 2010 2011 2012 2013 2014

Details for Mechanism ID: 10332
Country/Region: Zambia
Year: 2014
Main Partner: University of Nebraska
Main Partner Program: NA
Organizational Type: University
Funding Agency: HHS/NIH
Total Funding: $600,000 Additional Pipeline Funding: N/A

NOTE: The following is taken from summaries released by PEPFAR on the PEPFAR Data Dashboard. They are incomplete summary paragraphs only and do not contain the full mechanism details. When the full narratives are released, we will update the mechanism pages accordingly.

In line with WHO recommendations, the Zambian government has recommended ART for all infected infants. Infected infants will need to be identified, treated, monitored and be tested for the presence of ART resistant viruses at follow up to guide treatment options. Such monitoring will include not only CD4 count but viral load and genotyping for drug resistant viruses, which will continue to guide treatment for FY14 and beyond. The Zambian efforts to diagnose and treat HIV/AIDS remain largely hampered by a lack of infrastructure, resources, and trained personnel. The overall objective and goal is to continue our ongoing activities to support the UTH pediatric care and treatment program: perform HIV viral load testing, PCR diagnosis of exposed infants; provide pre-assessment service before commencement of ART; perform HIV genotyping to monitor drug resistant viruses; train laboratory personnel and; to develop human resources. This is essential to support the scale up and implementation of the anti-retroviral program in Zambia. We are anticipating a higher demand of the genotyping tests as more patients are being treated and more drug failure cases will be observed. To enhance cost-efficiency, cheaper in-house viral load and genotyping tests will need to be developed and adapted to reduce future cost, since these tests are essential for the guidance of clinical care.

M&E: There will be established standard operating procedures, documentation, data base and instrument calibration procedures and preventive maintenance. Our plan has been daily monitoring by our project director and laboratory manager. There will be internal QC checks and data validation. In addition, there will be a semi-annual evaluation of performance and system audits by US personnel.

Mechanism Allocation by Budget Code for Selected Year
Care: Pediatric Care and Support (PDCS) $250,000
Laboratory Infrastructure (HLAB) $350,000
Mechanism Target Information

Since COP2014, PEPFAR no longer produces narratives for every mechanism it funds. However, PEPFAR has now included performance targets or indicator information for each mechanism based on the Monitoring, Evaluation, and Reporting (MER) system. The MER guidance is available on PEPFAR's website https://www.pepfar.gov/reports/guidance/. Note that COP years 2014-2015 were under a previous version of the MER system and the indicators and definitions may have changed as of the new 2.0 guidance.

MER Indicator MER description Target Fiscal Year Target
HRH_PRE By Graduates: Laboratory professionals 2015 1
HRH_PRE By Graduates: Other 2015 5
HRH_PRE Number of new HCW who graduated from a pre-service training institution or program as a result of PEPFAR-supported strengthening efforts, within the reporting period, by select cadre 2015 6
HRH_PRE Sum of Graduates disaggregates 2015 6
LAB_CAP By clinical laboratories 2015 2
LAB_CAP By site support type: Direct Service Delivery (DSD) 2015 2
LAB_CAP Number of PEPFAR-supported testing facilities with capacity to perform clinical laboratory tests 2015 2
LAB_CAP Sum of Site Support Type disaggregates 2015 2
PMTCT_EID By infants who received their first virologic HIV test between 2 and 12 months of age 2015 10,000
PMTCT_EID By infants with a positive virologic test result within 12 months of birth 2015 700
PMTCT_EID Number of HIV- positive pregnant women identified during the reporting period (include known HIV-positive women at entry into PMTCT) 2015 11,000
PMTCT_EID Number of infants who had a virologic HIV test within 12 months of birth during the reporting period 2015 10,000
PMTCT_EID Sum of Infant Age disaggregates 2015 10,000
PMTCT_STAT Number of new ANC and L&D clients 2015 1,350
PMTCT_STAT Number of new ANC and L&D clients 2015 1,350
PMTCT_STAT Number of pregnant women with known HIV status (includes women who were tested for HIV and received their results) 2015 1,295
PMTCT_STAT Number of pregnant women with known HIV status (includes women who were tested for HIV and received their results) 2015 1,295
PMTCT_STAT_NGI Number of new ANC and L&D clients 2015 1,350
PMTCT_STAT_NGI Number of pregnant women with known HIV status (includes women who were tested for HIV and received their results) 2015 1,295
Cross Cutting Budget Categories and Known Amounts Total: $50,000
Education $50,000
Key Issues Identified in Mechanism
Child Survival Activities