Detailed Mechanism Funding and Narrative

Years of mechanism: 2008 2009

Details for Mechanism ID: 3013
Country/Region: Zambia
Year: 2009
Main Partner: U.S. Centers for Disease Control and Prevention
Main Partner Program: NA
Organizational Type: Own Agency
Funding Agency: HHS/CDC
Total Funding: $2,707,000

Funding for Biomedical Prevention: Prevention of Mother to Child Transmission (MTCT): $275,000

The funding level for this activity in FY 2009 has decreased since FY 2008. Narrative changes include

updates on progress made and expansion of activities.

Centers for Disease Control and Prevention (CDC)-Zambia will continue providing technical assistance to

the Ministry of Health (MOH), the National HIV/AIDS/STI/TB Council (NAC), and implementing partners in

the continued expansion of prevention of mother to child transmission of HIV (PMTCT) services nationally.

In FY 2006, direct support was provided in terms of educational materials for the national program, job aids

for health workers, an assessment on infant and young child feeding in the context of HIV/AIDS, and

national dissemination meetings for both national and international technical updates, an activity that CDC

will continue in FY 2009 as the area of materials development such as job aids tends to have gaps. Since

FY 2007, CDC-Zambia has continuously assisted the MOH to strengthen the monitoring and data system

from facility to national-level reporting using the CDC developed PMTCT monitoring system and the

SmartCare.

In an effort to improve the national PMTCT program and provide HIV treatment to children before they

become symptomatic, the United States Government (USG) has supported the Government of the Republic

of Zambia since FY 2006 to evaluate an inexpensive and less complex approach for use in the diagnosis of

infant HIV-1 infection in Zambia. Using FY 2005 funds, equipment for two different methods of infant HIV

diagnosis has been installed by CDC at the National Infant Diagnosis Reference Laboratory at the

University Teaching Hospital (UTH) in Lusaka. These methods include the regular Roche Amplicor 1.5

deoxyribonucleic acid (DNA) Polymerase Chain Reaction (PCR) assay and the Total nucleic assay (TNA)

assay which detects both ribonucleic acid (RNA) and DNA. Both techniques have performed very well in

quality assurance and quality control evaluations at the laboratory, including on dried blood spots collected

from infant heel sticks at University Teaching Hospital (UTH). A third DNA-PCR lab has been established

with USG support at the Arthur Davidson Pediatric Hospital in the Copperbelt Province and provides

services for the northern half of the country. By June 2007, a number of PMTCT sites across the country

had started sending infant dried blood spots routinely to the National Infant Diagnosis Reference Laboratory

in Lusaka. Early results showed that it is feasible to provide early infant testing facilities at both rural and

urban sites. In FY 2008, in collaboration with Clinton Foundation, PCR testing on infant dried blood spots

was rolled-out and implemented nationwide based on the courier systems linked to the three PCR reference

laboratories. In FY 2009, CDC will strengthen the linkages with the Pediatric Care and Support program to

ensure that there is continuity of care of the exposed infant through the integration of dried blood spots

(DBS) in routine maternal, neonatal and child health services.

In FY 2009, as in previous years, the USG will continue strengthening the national PMTCT program through

the procurement of back-up (buffer) supplies in-line with the U.S. Five-Year Global HIV/AIDS Strategy. As

part of this activity, the USG will procure supplies that are vital in the provision of the national minimum

package of PMTCT to avoid national stock-outs that would disrupt provision of services. CDC will support

the national PMTCT program with technical assistance and support for study tours and other relevant

programmatic reviews.

Lack of well defined male involvement activities in PMTCT has been cited as one of the compounding

factors that impact on the program significantly. Anecdotal evidence has attributed the lack of male

involvement to low levels of disclosure of HIV results of pregnant women to their husbands which lead to a

low uptake of both mother-infant ARV prophylaxes, few HIV positive women accessing care and treatment

services and inadequate support of infant feeding choices. In FY 2009, CDC in collaboration with USG

partners and the MOH will pilot a male involvement intervention that is community-based and that engages

pregnant women's partners in access to antenatal clinic (ANC) services. The pilot will offer prenatal

education, couple counseling and address male norms that act as barriers in male's participation in health

seeking behaviors in reproductive health. The objective of this pilot is to develop new interventions that

directly encourage men to participate in the birth preparedness of their children whilst challenging widely-

held male norms. This activity will also be linked with work being conducted by USG partners currently

working in the area of couple counseling. Secondly, CDC will partner with PMTCT implementing partners to

pilot an infant feeding intervention that explores and addresses infant feeding practices in the context of

HIV/AIDS. Activities that address: abrupt weaning, safe transition period during weaning, exclusive

breastfeeding and complementary feeding will be explored. Based on the results of the two pilots, full public

health evaluation protocols will be developed.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15588

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15588 3574.08 HHS/Centers for US Centers for 7192 3013.08 CDC Technical $375,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

9019 3574.07 HHS/Centers for US Centers for 5016 3013.07 CDC Technical $125,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

3574 3574.06 HHS/Centers for US Centers for 3013 3013.06 Technical $225,000

Disease Control & Disease Control Assistance

Prevention and Prevention

Emphasis Areas

Gender

* Addressing male norms and behaviors

Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.01:

Funding for Sexual Prevention: Other Sexual Prevention (HVOP): $140,000

This activity is linked to all prevention narratives, Abstinence and Being Faithful, Other Prevention including

Male Circumcision (MC) and all counseling and testing (CT) activities. It is also linked to antiretroviral (ART)

treatment section addressing prevention with positives as well counseling and testing. In FY 2009, the

focus will be providing technical assistance (TA) in working with communities and various points of care to

integrate prevention and to link to those who are negative and positive to the various community groups.

The TA will be provided to partners to implement the new prevention strategy expected to available in 2009.

Provincial meetings will he held with partners on the national strategy to build capacity of local Ministry of

Health (MOH) staff to take leadership in promoting comprehensive and effective prevention for

sustainability.

Zambia has a population of approximately 10 million citizens (US Department of State, 2006), and overall

HIV prevalence is still 14.3% among the general population and 13% among men (Zambia Demographic

Health Survey, 2002). While it is evident through the DHS survey that many Zambians know about

HIV/AIDS and its modes of transmission, there has been minimal reduction in HIV prevalence in Zambia in

the last few years, a clear indication that knowledge is not translating into behavior change as expected.

This

activity will work with the government, other donors, and experts from other PEPFAR countries to share

lessons learned and redirect prevention strategies in Zambia.

This activity will provide technical guidance in the implementation of PEPFAR activities in relation to care,

treatment, and prevention. This activity will be carried in close collaboration with Zambian partners and

USG agency technical specialists. In addition, the activity will provide oversight to ensure that PEPFAR

funded activities are programmatically sound and consistent with the Zambian National Health Strategic

Plan; train technical officers in relevant behavioral science to build local capacity; develop evaluation and

assessments to measure impact and programmatic effectiveness of interventions; recommend best

practices; participate in design of programs and represent the USG in national planning and technical

committees.

Funding for this activity will provide support for national/MOH sexually transmitted infections (STI) meetings

and prevention meetings as well as travel to the field to monitor implementation of prevention and CT

programs. Funds will also support international travel to, male circumcision (MC), counseling and testing

(CT), sexually transmitted infections (STI), and prevention conferences.

New/Continuing Activity: Continuing Activity

Continuing Activity: 19499

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

19499 19499.08 HHS/Centers for US Centers for 7192 3013.08 CDC Technical $90,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

Table 3.3.03:

Funding for Care: Adult Care and Support (HBHC): $30,000

FUNDING FOR THIS ACTIVITY HAS BEEN REDUCED FROM FY 2008.

In fiscal year FY 2008 funds under this activity were reprogrammed directly to the partner to support

purchase of a mobile Pediatric ART unit. FY 2009 funds are requested to provide technical assistance (TA)

in the area of care and support for both adults and children. The TA visits will focus on clinical care,

psychological care, spiritual care, social care, and prevention services and will often be combined with other

program area reviews around adult and pediatric treatment including wrap around activities. In addition

these funds will allow for one international travel to attend a relevant training, workshop, or symposium.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15590

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15590 9770.08 HHS/Centers for US Centers for 7192 3013.08 CDC Technical $30,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

9770 9770.07 HHS/Centers for US Centers for 5016 3013.07 CDC Technical $0

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

Table 3.3.08:

Funding for Treatment: Adult Treatment (HTXS): $298,000

ACTIVITY UNCHANGED FROM FY2008

The funding level for this activity in fiscal year (FY) 2009 has decreased since FY 2008 to support

implementing partner activities. Only minor narrative updates have been made to highlight progress and

achievements. This activity links to all antiretroviral therapy (ART) activities.

Implementation of the surveillance for antiretroviral (ARV) drug resistance is in process and technical

assistance for the development of surveillance for HIV-1 antiretroviral drug mutations has been provided by

the United States Government (USG).

The USG, through the Centers for Disease Control and Prevention (CDC), plans to continue providing

technical assistance to the Government of the Republic of Zambia on: 1) surveillance of antiretroviral (ARV)

drug resistance; 2) supervisory visits to project sites in four provinces to evaluate antiretroviral therapy

(ART) service delivery and quality improvement; 3) collaboration with MOH and the World Health

Organization (WHO) on ARV drug resistance surveillance; and 5) critical electronic medical record systems.

With the increased, widespread availability of ARV treatment in the public health sector, it is expected that

with time the numbers of drug resistance cases will increase. In FY 2005, in response to a specific request

from the Ministry of Health (MOH), the USG provided technical assistance to the national ART program in

developing a national plan for surveillance for HIV-1 antiretroviral drug mutations. In FY 2006 and 2007,

the USG provided support for the procurement of equipment and supplies, as well as training for laboratory

staff in testing for ARV drug resistance, in collaboration with Japan International Cooperation Agency, the

University of Nebraska-Lincoln, and the University of Alabama-Birmingham.

In FY 2008, the USG continued providing technical assistance to key sites to ensure ongoing monitoring of

drug resistance nationally, in close collaboration with the WHO, MOH, and all cooperating partners in

provision of ART services.

In FY 2008 funds supported technical assistance from CDC care and treatment and strategic information

(SI) teams to the national program focusing on a quality improvement initiative in coordination with SI

activities such as the expansion of the SmartCare Electronic Health Record system and an ART cluster

evaluation. SmartCare was identified as the national electronic medical record system for ART and is to be

used in all sites where a computer is used.

In FY 2009, ARV drug resistance testing will be scaled-up and also become part of HIV care among

children who maintain high viral loads despite ongoing treatment at the USG-supported Center of Excllence

for Pediatric and Family HIV Care at the University Teaching Hospital Department of Pediatrics. CDC will

continue providing technical support to the national ART program and its coordinator including quality

improvement, monitoring and evaluation, and health management information systems. In FY 2009, funds

will continue supporting technical assistance from CDC care and treatment and strategic information (SI)

teams to the national program focusing on a quality improvement initiative in coordination with SI activities

such as the expansion of the SmartCare Electronic Health Record system and an ART cluster evaluation.

CDC-Zambia staff will continue engaging with the WHO on ART quality and guideline updates for pediatric

and adult ART as well as medical information data standards. Occasional travel and local meetings are

required on these tasks. In addition, funds within this activity will also be used for staffing costs needed to

monitor the scale-up of ARV services and infrastructure rehabilitation.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15593

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15593 3846.08 HHS/Centers for US Centers for 7192 3013.08 CDC Technical $278,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

9026 3846.07 HHS/Centers for US Centers for 5016 3013.07 CDC Technical $648,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

3846 3846.06 HHS/Centers for US Centers for 3013 3013.06 Technical $350,000

Disease Control & Disease Control Assistance

Prevention and Prevention

Table 3.3.09:

Funding for Treatment: Adult Treatment (HTXS): $0

This PHE activity, "The role of supportive services in the provision of ART", was approved for inclusion in

the COP. The PHE tracking ID associated with this activity is ZM.07.0196.

New/Continuing Activity: Continuing Activity

Continuing Activity: 17704

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

17704 17704.08 HHS/Centers for US Centers for 7192 3013.08 CDC Technical $70,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

Table 3.3.09:

Funding for Care: TB/HIV (HVTB): $200,000

The funding level for this activity in FY 2009 will remain the same as in FY 2008. Only minor narrative

updates have been made to highlight progress and achievements

This activity relates to activities in counseling and testing (CT), laboratory infrastructure and support,

HIV/AIDS treatment services for adults and pediatrics.

This activity relates to activities in counseling and testing, laboratory infrastructure, palliative care: basic

health support activity, and HVTB (#9032, #9017, #8819, #8992, #9037, #9006, #9046, and #9010).

Provision for the following activities in support of the national implementation of TB/HIV activities is being

requested: 1) technical assistance for evaluation of surveillance system for TB/HIV implementation; 2.)

Provide supportive technical supervision to the Southern, Western, Eastern, and Lusaka provinces and 3)

inclusion of TB/HIV data elements in the SmartCare Electronic Health Records to improve patient care,

In FY 2007, the US Government (USG) provided support to the Ministry of Health (MOH) in the national

integration of Tuberculosis (TB) and HIV services by providing support to a variety of areas at the national

and local level, including support of TB policy processes, adaptation of guidelines and materials, and

preparation of TB clinical decision support systems. A National level TB/HIV coordinating body within the

MOH with the following membership; staff from the TB, HIV, CT units in MOH; multilateral organizations;

research groups; faith-based organizations; non-governmental organizations; and community

representatives.

This body was tasked with developing and implementing a single, coherent TB/HIV strategy, policy, and

communication message based on the best existing evidence. As a result national guidelines for the

implementation of TB/HIV activities were developed based on the World Health Organization (WHO) Interim

Guidelines for TB/HIV collaboration. Additional support was provided for the revision of TB data collection

forms and registers, based on WHO forms that incorporate the collection of HIV data. The USG produced

the revised patient treatment form, identification card, and registers that have been distributed to all

provinces and districts. Technical support was provided for the orientation of health staff in the new forms.

In addition the USG co-funded, with the MOH, WHO, and Jhpiego, a training of trainers session for an initial

group of 25 trainers in diagnostic counseling and testing using the national training module adapted by

JHPIEGO (#9032).

In FY 2007, the USG provided technical support to the MOH for the evaluation of surveillance systems for

TB/HIV implementation. A pilot evaluation of the revised TB/HIV reporting and recording systems in

Southern (21 health facilities) and Copperbelt provinces (17 health facilities) were sampled. The findings

showed that the recording and reporting systems needed strengthening and there was need to conduct a

country wide evaluation. In addition the evaluation identified weaknesses in the supervision of the health

facilities and in response the MOH has developed a supervisory tool that will be used by all TB officers and

allow for comparison of performance at different time points.

In FY 2008, the USG working in collaboration with the MOH and other partners conducted a similar

evaluation in Lusaka Province. The evaluation was done in Lusaka District, Kafue and Chongwe districts.

The evaluation brought out the strengths and weaknesses of the program which facilitated program

planning.

In FY 2008 the USG directly funded the NTP to repeat the evaluation of the national TB/HIV surveillance

system in all the remaining six provinces. The findings of this national evaluation will provide information on

how well the program is performing and will facilitate planning to make the NTP achieve better out comes in

TB/HIV activities. Technical assistance for this evaluation would be provided for by the USG in conjunction

with other members of the National TB/HIV coordinating Committee.

In FY 2008 the USG provided supportive technical assistance to the NTP through supervision to the

provinces, districts and health facilities in Southern, Western, Eastern, and Lusaka provinces. During these

visits, on the job training to over 100 health care workers was provided. The supervision team combined

with the National TB program staff and other partners in TB and HIV control Programs.

In FY 2009, the USG will continue to provide technical supportive supervision to the four provinces.

Program coordinators at provincial, District and health facility levels and community volunteers will receive

on the job training. It is expected that 120 health care providers will be reached during this period.

This activity is related to activity #9023. To sustain policy and clinical decision-making for future expansion

of national TB activities, CDC has assisted the MOH in establishing an Electronic Medical Health Record

(EMR) standard that now includes TB data as well as HIV and other opportunistic infections (OI's) data. In

the last year, this EMR, now called SmartCare (previously called CCPTS), was established as the national

standard software for use in any clinic that could support a computer. This remarkable consensus

achievement by the MOH is being followed by national training and deployment at the same time as there is

ongoing development of the out patient department (OPD) module that will include TB care planned for

release in 2007. The SmartCare already addresses TB care in the context of antiretroviral (ART) services,

but the pending OPD module will establish a bidirectional link between OPD TB services and ART TB

services provided either by a patient-carried smart card or via a periodic facility-by-facility database ‘merge'.

The EMR system and SmartCard carries a longitudinal record of a client's medical history, including prior

illness, physical findings, lab results, symptoms, problem list with diagnoses, and treatment plan for all

these services. A paper and electronic copy of patient information is maintained at all clinics visited, and

paper records are still used for primary data capture in most settings. Accessible and integrated information

provides one basis for improved TB care, and this will become available in the higher density settings in

2007. As the core element of the SmartCare system, the electronic record provides: 1) more fully informed

local decision support; 2) reminder reports to staff to help keep patients from "falling through the cracks" (to

assure adherence and minimize resistance); and 3) improved management of general facility operations

(such as drug utilization) by automating key management elements of local monitoring and evaluation and

Activity Narrative: logistics support.

During May and June 2007, with strong USG support, the MOH held a series of three national trainings for

180 district and provincial leaders from all 72 provinces, as part of scaling up the SmartCare deployment.

In FY 2008, emphases will be on refinement of the TB service within the OPD module, addition of suitable

decision support cross-referencing other health conditions and potentially interacting medications, and

primarily scaling-up of this service increasing numbers of clinics nationwide. Building on previous year's

successes in HIV and antenatal clinic/prevention of mother to child transmission/CT services, SmartCare is

now supporting around 90,000 PLWHA. This year's funding will increasingly focus on building the capacity

of the MOH and collaborators within Zambia to implement and scale-up the TB/HIV module of the

SmartCare for purposes of sustainability, and to operationalize automatic links between increasing numbers

of SmartCare service modules in order to better care for TB-HIV patients with these concurrent illnesses

and OI's. Together with the related activities, these funds help assure that the OPD TB to HIV services link

spreads throughout the country with this same deployment effort.

The USG has provided direct funding to the MOH through a co-operative agreement since 2004 (activity

9008) for activities related to strategic information and more specifically to Information Technology (IT) such

as setting up a local area network at the headquarters and IT supervisory support to the provinces and

districts around the country. Since FY 2007 the USG increased the level of funding and scope of activities

supported through this mechanism to include other program areas such as PMTCT (ref 9737), TB (ref

12445), ARV services (ref 9754), and laboratory (ref 8991). The funding provided through this mechanism

enabled the MOH technical program officers to coordinate national level activities and enhance their

capacity for supervision and technical support to the lower levels of the health system. The increase in

funding and scope of activities brought with it added challenges in assuring that activities are conducted as

planned and that the reporting of the activities is coordinated.

Targets set for this activity cover a period ending September 30, 2010.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15592

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15592 3645.08 HHS/Centers for US Centers for 7192 3013.08 CDC Technical $200,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

9021 3645.07 HHS/Centers for US Centers for 5016 3013.07 CDC Technical $171,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

3645 3645.06 HHS/Centers for US Centers for 3013 3013.06 Technical $376,000

Disease Control & Disease Control Assistance

Prevention and Prevention

Emphasis Areas

Health-related Wraparound Programs

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $100,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.12:

Funding for Care: TB/HIV (HVTB): $124,000

The funding level for this activity in fiscal year (FY) 2009 will remain the same as in FY 2008. Only minor

narrative updates have been made to highlight progress and achievements.

Activity Narrative:

This activity relates to activities in counseling and testing, laboratory infrastructure, palliative care, and basic

health support activities.

The following activities are being requested:

1) Printing of the participant's manual for training tuberculosis (TB)/HIV treatment supporters. 2) Printing of

TB/HIV news letter. 3) Program evaluation of the use of cotrimoxazole for HIV-positive TB patients in TB

clinical settings.

TB remains a major health problem in the health care delivery in Zambia. The incidence and prevalence

rates continue to increase from 1985 due to HIV/AIDS. The burden of TB has risen more than five-fold since

HIV/AIDS was first diagnosed in Zambia. It is estimated that 50-70% of all TB patients are co-infected with

HIV. The increase in the number of HIV/AIDS related diseases has made it difficult for the health care

system to accommodate all the chronically sick and TB patients in hospital wards. Many of these patients

are therefore discharged or referred to be managed in their homes by the community health care providers

with technical support from the trained health staff. The Ministry of Health (MOH) has also been highly

burdened by the attrition of trained health staff through resignations, deaths, retirements and other reasons.

Many health centers are managed by one or two trained staff. Others are managed by non health trained

staff.

Community initiatives implemented in Ndola by World Health Organization (WHO) in 1998 and Monze by

the Catholic Church showed better results in terms of case holding and better TB out comes. These

community initiatives demonstrated that effective community participation is key for successful Stop TB

strategy.

The Ministry of Health (MOH) through Central Board of Health endorsed the integrated community based

DOTS approach in order to strengthen TB control in the district hospitals and health centers. This new

approach aims to provide a quality integrated TB services to the people by means of standardized

diagnosis, care, support and community based treatment.

In Zambia there are three Directly Observed Treatment (DOT) Plans that are used for TB patients. Two of

these DOT plans are implemented at community level. The DOT Plan V (Volunteer) is where the TB

patients are being directly supervised and observed as they swallow the anti TB drugs by the community

volunteer on daily basis. DOT Plan R (Relative) is when the patient is supervised and observed as they

swallow anti TB drugs by the relatives daily. In both plans it entails providing health education to the patient

and the family, to observe for side effects, document the drugs intake after every dose and refer patients to

health facilities for review among other functions at community level.

In order to expand the community based Stop TB strategy, health workers, and community volunteers need

standardized knowledge and skills.

In 2005, the USG directly supported the development and printing of a facilitators manual for training TB

treatment supporters. This manual was developed in collaboration with the Ministry of Health, the USG,

various community based organizations and the TB committee of Care and Treatment working Group. This

manual is widely used by the MOH institutions, Non governmental organizations, community based

organizations and faith based organizations when training the TB treatment supporters.

By the end of FY 2008, the facilitator's manual would have been updated to include new treatment

guidelines of the four fixed drug combination and TB/HIV information. After the revision and updates, this

manual would have been printed and distributed to all the Provinces to facilitate quality knowledge and skills

to the facilitators. One-thousand (1,000) copies were produced and distributed to users.

In FY 2009, due to the demand for this manual by trainers in government health institutions, community

based organizations, faith based organizations, and other users, an additional 1000 copies will be

produced. Despite the availability of this facilitators manual for training TB treatment supporters, a gap still

exist in terms of material for the community volunteers to refer to after the training.

By the end of FY 2008, the USG would have developed and produced a reference hand-book for the

treatment supporters. This hand book will be in line with the materials in the Facilitators manual for the

training of TB treatment supporters. It is hoped that 65-70% of volunteers to be trained in the country would

be given a copy of the Participant's hand book for training TB/HIV treatment supporters. A total of 3000

copies were produced and distributed to community volunteers.

In FY 2009, due to the high number of community TB treatment supporters in the country, another 2,000

copies will be produced to facilitate each trained community volunteer to be in possession of the

participant's manual.

TB/HIV co-infection has presented a lot of challenges in the management of these diseases such as; the

diagnosis, care, support and treatment (fixed TB drug combination and the co-treatment with ART),

mobilization of communities, incentives for the volunteers and patient involvement; screening, counseling

and testing of TB patients for HIV; and screening of HIV infected patients for TB. Other issues include

development of linkages and referral of patients between the\ different service areas; the recording and

reporting of TB/HIV information on the data collecting and reporting tools and challenges to do with infection

control in TB/HIV settings, patient, family and community education.

Some of these challenges are handled some what different from place to place depending upon the

knowledge and skills the health care workers and the community volunteers have and the different

administrative support given. There is therefore a need to ensure that experiences in implementation of

Activity Narrative: TB/HIV activities indifferent provinces and districts are shared.

In FY 2008, the USG closely collaborated with the MOH National TB program to solicit for articles on

TB/HIV from the Provincial Health Offices, districts and the communities and other partners in order to

share knowledge, skills and other experiences in the management of the challenges in TB/HIV

programming. Using these materials a TB/HIV newsletter was produced and distributed to stakeholders. A

total of 5,000 copies were printed and distributed to the TB and HIV program implementers and other

interested parties. It is hoped that this newsletter will go a long way in providing technical support to the

different players in TB/HIV by applying positive strategies used else where to implement activities which

were challenging.

In FY 2009, the production of this newsletter will continue and be produced bi-annually. Each publication will

produce 5,000 copies for distribution to stakeholders.

The provision of cotrimoxazole (CTX) prophylaxis for HIV positive TB patients has been included in the

national TB/HIV Guidelines adapted by the MOH. However the provision of CTX to the HIV-infected TB

patients has primarily occurred within the ART clinics and not in the TB clinics due to a concern that adding

CTX to the duties of the TB staff would overload them and compromise the TB care provided. Whilst all HIV

positive TB patients are referred for HIV care and treatment to the HIV clinics, which tend not to be co-

located in the same clinic as the TB services, it is recognized that this does result in some TB patients not

accessing HIV care for a variety of reasons. These include not reaching the HIV clinic or not being attended

to in a timely fashion due to the large number of patients attending these clinics coupled with health workers

shortages. A recent evaluation of the TB surveillance system revealed that less than 20% HIV-infected TB

patients have documented evidence that they were receiving CTX. In 2009 the USG will work with the

MOH and other partners to develop a pilot program to provide CTX in three TB clinics in two provinces

(Eastern and Western). The program will be evaluated in order to determine whether provision of CTX in

the TB clinic is feasible within the Zambian context and provide information to the MOH on how CTX

prophylaxis can be widely implemented in TB clinical settings. The program will also provide information on

how referrals between TB and HIV clinics can be improved.

Targets set for this activity cover a period ending September 30, 2010.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15601

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15601 3884.08 HHS/Centers for US Centers for 7192 3013.08 CDC Technical $124,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

9010 3884.07 HHS/Centers for US Centers for 5010 3104.07 CDC (Base) $124,000

Disease Control & Disease Control

Prevention and Prevention

3884 3884.06 HHS/Centers for US Centers for 3104 3104.06 $124,000

Disease Control & Disease Control

Prevention and Prevention

Emphasis Areas

Health-related Wraparound Programs

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $124,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.12:

Funding for Laboratory Infrastructure (HLAB): $100,000

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

April 2009 Reprogramming: Reduction in overall amount of funds; $600,000 total has been reprogrammed

to 3 implementing partners.

To strengthen national laboratory quality assurance programs, strengthen laboratory infrastructure and

facilities, build local human capacity, and to provide technical assistance.

This activity is linked to VCT (#9714), PMTCT (# 0631), TB/HIV (#0724), pediatric and adult care and

treatment and strategic information (SI #3714) program areas and to all activities in the laboratory

infrastructure section (#3701, 3702, 3703, 3704, 3754, 9794, 9795, 9796, 9797, 9798, 9799, 16956, 9524,

3541, 9524, 16420).

Technical expertise, material support, and human resource capacity strengthening are critical for building a

sustainable laboratory program for diagnosing and managing treatment of HIV/AIDS, TB, and other

opportunistic infections. In FY 2005-2008, the Laboratory Infrastructure and Support Branch of CDC

Zambia has made significant progress to support laboratories throughout the four provinces (Lusaka,

Southern, Western and Eastern) to provide laboratory services to care and treat people living with HIV/AIDS

(PLWHA). Diagnostic capacity for TB and bacterial infections in Zambia is in an advanced stage, more so

than many other PEPFAR countries. Automated laboratory equipment (including but not limited to CD4,

hematology, chemistry) were procured, installed and maintained. Local staff received training and

supervision. Strategic laboratory reagents and consumable acquisitions with national maintenance and

service agreements for automated systems were provided.

In FY 2008, this activity supported: 1) expansion of laboratory technical expertise through training and

quality assurance (QA) to the Ministry of Health (MOH) laboratories, national reference laboratories,

provincial, district, urban and rural health centers and included University Teaching Hospital ; 2) continued

to develop, renovate, and expand the pre-service laboratory training center at Chainama College in Lusaka

in support for HIV rapid testing, TB AFB smear microscopy, CD4 staging, liver and kidney function testing,

and treatment services; 3) implementation and monitoring of a laboratory information system for data

management to improve the documentation of patient test results, tracking of reagent procurement and

consumption, and QA efforts; 4) strengthen the palliative care system by improving detection and treatment

of opportunistic infections commonly associated with HIV/AIDS; 5) provide technical support for infant HIV

diagnosis with dried blood spot analysis in children at the Arthur Davison Children's Hospital in Ndola and in

Lusaka Zambia; 6) support much needed renovations and improvements in laboratory infrastructure at key

district-level health facilities in Eastern, Lusaka, Southern, and Western Provinces; 7) provide travel support

for Zambia CDC laboratory staff for on-site QA/quality control (QC) supervisory training and visits to testing

sites throughout the country to ensure proper equipment operations, provide feedback, troubleshoot, and

reinforce systems strengthening; and, 8) coordinate with the MOH, UTH, and other partners to develop a

national training curriculum for HIV rapid testing and trainer of trainers.

In FY 2009, CDC will focus on strengthening the national QA program for rapid HIV testing in Zambia. In

this regard, CDC will conduct the following activities: 1) co-ordinate and provide technical support the MOH,

UTH Virology (UTH-VL), and other partners to implement the national QA program for rapid HIV testing

according to the national guidelines for HIV counseling and testing; 2) co-ordinate a course for HIV rapid

test training of trainers. This will include partners' laboratory staff as well as CDC Zambian laboratory

specialists. A national laboratory training team will be formed; 3) co-ordinate roll out training of the national

algorithm that includes the component of quality assurance and quality control for HIV rapid testing to both

technical and non-technical laboratory persons in VCT, PMTCT, and integrated HIV/TB programs within the

four provinces named above; 4) support CDC laboratory staff to travel within the country to perform on-site

training, supervisory visits and re-testing to healthcare facilities within the four provinces that conduct rapid

HIV testing. Four CDC local laboratory staff will be assigned as CDC regional laboratory points of contact

and be responsible for the QA program of each province. They will work and coordinate closely with the

MOH, UTH, and the provincial laboratory personnel to ensure timely feedback and troubleshooting; 5) co-

ordinate with Zambian Provincial Care and Treatment program (ZPCT) staff to train and develop skill

capacity to standardize the quality of HIV rapid testing in the rest of the country (Central, North, Northeast

and North-Western regions where ZPCT is providing technical assistance; 6) co-ordinate and support

quality assurance and quality control workshops for rapid HIV testing, TB acid fast bacilli (AFB) smear

microscopy, CD4, hematology, and chemistry; 7) provide technical assistance to the MOH and UTH staff to

establish a functional national external quality assurance scheme (EQAS) for HIV rapid testing in order to

assess the quality and accuracy of sites performing rapid HIV testing. Skill and technology will be

transferred to the MOH and UTH staff to generate panels of dried tube specimens consisting of HIV positive

and negative samples. The panels will be distributed to sites throughout the country; 8) assist the MOH and

UTH staff to collect and analyze data at the MOH central collection point, and disseminate the national

EQAS data through workshops, scientific meetings and/or conferences; 9) provide technical assistance to

healthcare personnel at sites to follow up on the results, delivery and outcome of the EQAS as well as to

troubleshoot and provide technical guidance for corrective action and 10) provide technical assistance to

USG SI team and its partners (TDRC and UTH Virology) on laboratory testing related to surveillance

activities in Zambia supported by PEPFAR.

In addition, in FY 2009, CDC will focus on providing technical assistance to the MOH through coordination

with partners to support the following activities: 1) develop an integrated national QA program for laboratory

testing including rapid HIV testing, CD4, early infant diagnosis using PCR, TB smear, and malaria

diagnosis. The latter activity will be performed in collaboration with President's Malaria Initiative (PMI) staff

in Zambia; 2) develop a Laboratory Information System in collaboration with other partners; 3) to assess the

electrical supply situation at various laboratories in the health centers in remote areas where interruptions

are common and assist in developing a sustainable continuous electrical supply; 4) to review the five year

national laboratory strategic plan; 5) assist the MOH to review national curriculum for laboratory technologist

schools when need arises. Currently, the MOH with support from the Clinton Foundation has started a

process to revise the curriculum. The MOH will call upon assistance from CDC when the draft is ready for

Activity Narrative: revision; and 6) provide technical assistance to the MOH such as reviewing its documents (the national

medical laboratories policy, the national laboratory safety manual), attending meetings organized by the

MOH as well as support the MOH laboratory-related activities when call upon.

Furthermore, in FY 2009, the funds will be used to support the following activities: 1) coordination with

donors such as the Global Fund, World Health Organization (WHO), PMI, USAID, and Japanese

International Cooperative Agency (JICA) to ensure harmonization and to avoid duplication of funds and

technical support; 2) training of provincial laboratory personnel and CDC Zambian laboratory specialists to

be diverse in all laboratory testing procedures conducted in clinical laboratories at all levels including

laboratory management and QA/QC for supervision purposes; 3) coordination and support to lab-related

workshops; 4) continuation of provision of technical assistance and QA through CDC regional laboratory

points of contact to laboratories, to ensure the quality of its services for PLWHA is maintained; 5) the

national TB laboratory network, the TB AFB QA/QC program, TB culture and drug susceptibility testing for

rapid detection of multiple and extreme resistant cases of tuberculosis; 6) continue to support bacteriology

laboratories at UTH and provincial general hospitals for diagnosis of HIV-related opportunistic infections; 7)

provide technical support and training for the expansion of infant diagnosis utilizing PCR techniques at

Maina Soko Military Hospital and Livingstone General Hospital; 8) provide technical assistance to DOD for

the expansion of the military clinical and laboratory services in Zambia; and 9) provide technical assistance

to other PEPFAR program areas including Biomedical Injection and Blood Safety.

In summary, in FY 2009, CDC will continue to provide support to all the above listed activities to improve

and build sustainable laboratory systems in Zambia by strengthening the national QA program and

laboratory infrastructure, through provision of technical assistance to support continuous professional

development of laboratory personnel by pre- and in-service training; and through coordination.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15594

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15594 3706.08 HHS/Centers for US Centers for 7192 3013.08 CDC Technical $1,249,900

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

9022 3706.07 HHS/Centers for US Centers for 5016 3013.07 CDC Technical $890,001

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

3706 3706.06 HHS/Centers for US Centers for 3013 3013.06 Technical $1,162,676

Disease Control & Disease Control Assistance

Prevention and Prevention

Emphasis Areas

Health-related Wraparound Programs

* TB

Workplace Programs

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $400,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.16:

Funding for Strategic Information (HVSI): $1,490,000

ACTIVITY HAS BEEN MODIFIED IN TE FOLLOWING WAYS:

Support to MOH staff in analytic skills training is added.

This activity relates to Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) Strategic Information (SI)

(#3709.08), JHPIEGO SI (#3710.08), AIDSRelief - Catholic Relief Services (CRS) (#3711.08), Ministry of

Health (MOH) (#3713.08), National HIV/AIDS/STI/TB Council (NAC) (#3716.08), SI Central Statistical

Office (CSO) (#3717.08), Tropical Diseases Research Centre (TDRC) (#3718.08), Eastern Provincial

Health Office (EPHO) (#9693.08), Western Provincial Health Office (WPHO) (#9696.08), Zambia National

Blood Transfusion Service (ZNBTS) (#9698.08), and SmartCare COMFORCE (#9692.08).

Continuing work from FY 2008 CDC's SI activities provide critical support to information systems, building

sustainable monitoring and evaluation (M&E) capacity, and ensuring that essential information from sentinel

surveillance, national health surveys, clinical information systems, and targeted evaluations is obtained and

used to improve quality of care. Core systems must be institutionalized to sustain improved quality of care,

decision-making about resources, and improved service delivery mechanisms. CDC provides technical and

financial support to the MOH and the NAC at central, provincial, district levels, the CSO, TDRC, the

University of Zambia (UNZA) School of Medicine (SOM), and a number of other partners. Built around the

SmartCare the anchor information system project is formerly known as the Continuity of Care and Patient

Tracking System (CCPTS). This information system has been adopted by the MOH as a national standard;

in the next funding cycle, there will be an evaluation of the SmartCare program. CDC Zambia is continuing

to help institute durable systems for quality health services, disease surveillance, and M&E.

The first component relates to direct support to the official CDC office locations and collocated partners

which require one-time and on-going improvements to their information systems infrastructure. These office

locations are at the U.S. Embassy, University Teaching Hospital (UTH) Pediatric Center of Excellence,

Chest Diseases Laboratory (CDL), Intercontinental Hotel in Lusaka, and a growing number of offices based

at the Provincial Health Offices, such as in Livingstone in Southern Province, Chipata in Eastern Province

and Mongu in Western Province. This activity will fund the following: (1) continued procurement,

maintenance, and replacement of IT equipment for the new Pediatric and Family Center of Excellence at

UTH such as computers, consumables and other related equipment for the offices, communications

systems, equipment for training and conference facilities, integrate power supply systems for server and

core equipment; (2) maintenance contracts for printers & computers, continued network operability for

remote sites, VSAT and terrestrial communication links, and network hardware; (3) training for CDC and

partner IT staff in networking and server administration; (4)Continued support to the ZNBTS on linking

SmartCare to the national donor retention database and continued salary support for CDC staff.

FY 2009 funds will also support M&E activities to: (1) continue technical support to the national M&E

capacity and workforce building initiative in cooperation with NAC, MOH, SHARE, Peace Corps, the

University of Zambia, and National Alliance of State & Territorial AIDS Directors (NASTAD) to deliver

performance-based ongoing training, mentoring, and scholarships to partners, Provincial AIDS

Coordinators, District Planners, and District and Provincial AIDS Task Forces. USG support includes

technical assistance and support to national meetings, joint field and quality assurance monitoring; (2)

finalize and disseminate a system dynamics evaluation of antiretroviral therapy (ART) treatment success

and the role of ancillary services (approved and implemented as a PHE under HTXS in 2008). This

exercise engages stakeholders in considering various program options for national ART service delivery

sites and supportive services (e.g. food, psychosocial support). The model and its results will be

disseminated through conferences, invitational travel, and scholarly manuscripts; (3) develop appropriate

tools, manuals and quality assurance processes for SmartCare implementation; (4) Provide technical

support to Provincial Health Offices for M&E, SmartCare deployment and performance and data quality

assessments; (5) Continue to support Zambian M&E professionals to publish as well as present at regional

and international conferences on operational and evaluation research.

Lastly, FY 2009 funds will support the following HIV/AIDS surveillance activities: (1) continue technical and

material support to GRZ in its surveillance and reporting of HIV and syphilis prevalence through 27

antenatal clinic sentinel sites (ANCSS) and refugee camps; toward the end of FY 2008 preparations for

2010 round must commence. This activity is conducted in collaboration with the MOH, the CSO, UTH,

NAC, TDRC, and United Nations High Commission for Refugees (UNHCR); (2) support the GRZ in its

surveillance of HIV incidence and prevalence of other important viral infections over time, and by testing

blood specimens from the antenatal clinic sentinel surveillance (1994-2008) and the Zambia Demographic

and Health Survey using the BED-CEIA assay developed at the CDC to allow the estimation of recent HIV

infections (incidence); (3) partner with the private sector in Zambia to strengthen surveillance and reporting

of HIV prevalence and incidence among workers in the agricultural and other industries; FY 2009 funding

will allow us, together with partners, to utilize the findings and to develop the methods and tools to

strengthen the continuity of HIV care for migrant workers during the work season and to help establish

linkage to care upon their return to home regions; (4) continue to strengthen and work towards sustaining

the National Cancer Registry of Zambia and the Cancer Diseases Hospital in their surveillance and

reporting of AIDS-related malignancies through technical and material assistance. Surveillance of AIDS-

related cancers is important both for GRZ planning of cancer treatment needs and preventive interventions

in the population, and for monitoring the impact of ART scale-up on the risk of AIDS complications and

survival; (5) support the CSO to expand the Sample Vital Registration with Verbal Autopsy (SAVVY) System

in selected regions in Zambia, to validate the data capture instruments, and to evaluate the SAVVY

implementing process. This activity builds upon the Feasibility Study conducted in FY 2007 by CSO in its

surveillance and reporting of vital events in Zambia and will add coverage areas beyond the pilot sites. The

FY 2009 plan aims to strengthen and sustain the CSO office and expand expertise for vital registration in

Zambia; (6) collaborate with the World Health Organization to provide assistance to the MOH in establishing

a system to monitor the prevalence of transmitted HIV drug resistance (HIVDR) observed among young

women attending antenatal clinic. Such a system will strengthen the MOH HIVDR Working Group to

develop and implement a national strategy for HIVDR resistance monitoring, design and implementation of

appropriate study populations in which to monitor HIVDR and to collect information on behavioral and other

risk factors associated with increased risk of HIVDR development, technical support to build laboratory

Activity Narrative: capacity to perform genotypic HIV drug resistance testing, management and analysis of data on the

magnitude of HIVDR in the selected study population, and the coordination of report dissemination to the

GRZ, health professionals, the public, and the scientific literature; (7) through TDRC, support the

surveillance of HIV/AIDS in prison populations in Zambia; (8) ensure the sustainability of HIV surveillance

activities by providing expertise and coordinating training courses to increase long-term Zambian human

resource capacity in data management, statistical analysis, data use and interpretation, scientific writing,

and preparation of manuscripts for publications in scientific literature; (9) through MOH, improve Zambia's

geographic data layers and data infrastructure needed to utilize geographic information and geographic

mapping to support HIV/AIDS monitoring, evaluation, and response.

Targets set for this activity cover a period ending September 30, 2010.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15595

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15595 3714.08 HHS/Centers for US Centers for 7192 3013.08 CDC Technical $1,949,900

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

9023 3714.07 HHS/Centers for US Centers for 5016 3013.07 CDC Technical $2,240,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

3714 3714.06 HHS/Centers for US Centers for 3013 3013.06 Technical $860,768

Disease Control & Disease Control Assistance

Prevention and Prevention

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $75,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.17:

Funding for Health Systems Strengthening (OHSS): $50,000

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

The funding level for this activity in FY 2008 will be substantially reduced in FY 2009, reflecting increased

reliance in FY 2009 on local partners for the particular systems strengthening activity of equipment

acquisition. Otherwise minor narrative updates have been made to highlight progress and achievements.

CDC supports improved data management, dissemination, and data for decision-making in the delivery and

management of health services in national and local institutions in Zambia. Systems beyond the realm of

traditional strategic information activities require support to ensure efficient treatment and care capabilities

in all facilities. Using FY 2005 and FY 2006 funds, CDC procured 662 desktop computers and 34 laptops

for various institutions and affiliated United States Government projects focused on HIV/AIDS. In FY 2007,

CDC provided expanded support to laboratory informatics and remained responsive to equipment needs in

local health offices in targeted provinces. In FY 2008, some of this type of support was no longer optimal or

possible through this mechanism, although, specific ongoing technical support for infrastructure

enhancement was provided for the Chest Diseases Laboratory (CDL) and the Tropical Diseases Research

Center (TDRC) tuberculosis (TB) laboratory. In FY 2009, CDC will continue to provide technical support on

installation, routine maintenance planning, software licensing, and input on establishing relationships

between assisted organizations and technical support providers in Zambia. This will require frequent

supportive supervision visits by CDC staff to active project sites or for CDC to engage other technical

support as required, including a growing emphasis in training for systems strengthening. As an instance, in

FY 2009 increased use of computer based distance learning methods will employed, building on successful

preparation of DVD based training materials in FY 2008. Lastly, as CDC has staff placements at increasing

numbers of locations around the country providing direct support and technical assistance (TA) at provincial

health offices, there are increasing communication costs supporting dedicated lines to the central offices, in

addition to the infrastructure support at these sites (see also CDC-TA under HVSI).

New/Continuing Activity: Continuing Activity

Continuing Activity: 15596

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15596 3721.08 HHS/Centers for US Centers for 7192 3013.08 CDC Technical $500,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

9024 3721.07 HHS/Centers for US Centers for 5016 3013.07 CDC Technical $500,000

Disease Control & Disease Control Assistance

Prevention and Prevention (GHAI)

3721 3721.06 HHS/Centers for US Centers for 3013 3013.06 Technical $300,000

Disease Control & Disease Control Assistance

Prevention and Prevention

Table 3.3.18:

Cross Cutting Budget Categories and Known Amounts Total: $699,000
Human Resources for Health $100,000
Human Resources for Health $124,000
Human Resources for Health $400,000
Human Resources for Health $75,000