Detailed Mechanism Funding and Narrative

Years of mechanism: 2008 2009

Details for Mechanism ID: 3011
Country/Region: Zambia
Year: 2009
Main Partner: Comforce
Main Partner Program: NA
Organizational Type: Private Contractor
Funding Agency: HHS/CDC
Total Funding: $1,085,000

Funding for Sexual Prevention: Abstinence/Be Faithful (HVAB): $150,000

Related activities: Eastern Province Health Office HVCT (#9005), Southern Province Health Office HVCT,

(#9018), and Western Province Health Office HVCT (#9047) and all other prevention and counseling and

testing (CT) activities under CDC.

This activity is linked to all prevention narratives, AB, Other Prevention including Male Circumcision. It is

also linked to antiretroviral (ARV) treatment section addressing prevention with positives as well CT. In FY

2009, the focus will be providing technical assistance (TA) in working with communities and various points

of care to integrate prevention and to link those who are negative and positive to the various discussion

groups at the clinics and community. The TA will be provided to partners to implement the new prevention

strategy expected to available in FY 2009. Provincial meetings will he held with partners to address the key

areas of the national strategy and to build capacity of local USG staff to take leadership in promoting

comprehensive and effective prevention for sustainability.

Zambia has a population of approximately 10 million citizens (US Department of State, 2006), and overall

HIV prevalence is still 14.3% among the general population and 13% among men (Zambia Demographic

Health Survey (DHS, 2005). While it is evident through the DHS survey that many Zambians know about

HIV/AIDS and its modes of transmission, there has been minimal reduction in HIV prevalence in Zambia in

the last few years. A clear indication that knowledge is not translating into behavior change as expected.

This activity will work with the government, other donors and experts from other PEPFAR countries to share

lessons learned and revitalize prevention strategies in Zambia.

Funding for this activity will provide behavioral science support for care, treatment, and prevention services

to people living with HIV/AIDS and other opportunistic infections while developing leadership in the

behavioral science arena. This activity will provide technical guidance in the implementation of PEPFAR

activities in relation to care, treatment, and prevention. This activity will be in close collaboration with

Zambian implementing partners and other USG agency technical specialists. In addition, the activity will

provide oversight to ensure that PEPFAR-funded activities are programmatically sound and consistent with

the Zambian National Health Strategic Plan; train technical officers in relevant behavioral science to build

local capacity; develop evaluation and assessments to measure impact and programmatic effectiveness of

interventions; recommend best practices; participate in design of programs and represent the USG in

national planning and technical committees.

New/Continuing Activity: Continuing Activity

Continuing Activity: 17577

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

17577 17577.08 HHS/Centers for Comforce 7169 3011.08 Comforce $100,000

Disease Control &

Prevention

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $150,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.02:

Funding for Testing: HIV Testing and Counseling (HVCT): $135,000

Related activities: Eastern Province Health Office HVCT (#9005), Southern Province Health Office HVCT,

(#9018), and Western Province Health Office HVCT (#9047) and all other CT activities under CDC.

Funding in FY 2009 is requested to provide technical assistance (TA) for the scale-up of counseling and

testing (CT) access for rural disadvantaged communities, migrant populations, and general population in

Zambia. CT is scaling-up rapidly in Zambia and extending access to many rural areas hence increasing the

need for oversight and monitoring to ensure quality of services. The TA will make certain that couple

counseling and testing (CCT) is prioritized and training for capacity building is provided to partners on

couples CT for prevention. Emphasis will be on the new Zambian testing protocols, data management and

quality assurance and that appropriate data is being captured at all sites and reported accordingly.

The TA will also ensure that all CT programs are all working in collaboration with government under the

MOH and remain within the confines of government health guidelines. The focus will be to establish a

sustainable program through training of health care workers, developing standard testing protocols,

strengthening physical and equipment infrastructures, implementing facility level quality assurance/quality

improvement program, improving laboratory equipment and systems and development, and strengthening

health information systems.

New/Continuing Activity: Continuing Activity

Continuing Activity: 17357

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

17357 17357.08 HHS/Centers for Comforce 7169 3011.08 Comforce $85,000

Disease Control &

Prevention

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $135,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Program Budget Code: 15 - HTXD ARV Drugs

Total Planned Funding for Program Budget Code: $26,864,913

Total Planned Funding for Program Budget Code: $0

Program Area Narrative:

Sustaining access to anti-retroviral therapy (ART) is a key U.S. objective, Antiretroviral (ARV) drug procurement and enhancing

the capacity of the supply chain management systems are priority areas. Great progress was made in improving the availability of

ARV drugs at the national level during FYs 2005 - 2008.

With about one million Zambians living with HIV/AIDS and 200,000-250,000 of these persons requiring ART, the Government of

the Republic of Zambia (GRZ) has prioritized making ART available to all Zambians in need—as evidenced by the August 2005

policy rendering all public sector ART services free of charge. As of March 31, 2008 there were 172,022 people on treatment, up

from 110,000 in August 2007.

In FYs 2005 and 2006, the U.S. Mission in Zambia and JSI/DELIVER took the lead, in close collaboration with GRZ, to facilitate

the development of multi-year ARV drug forecasts and quantifications; these are now updated on a quarterly basis. The process

included developing the first national, long-term ARV drug procurement plan. The plan encompassed procurements made by the

U.S. Mission in Zambia, GRZ, the Global Fund to Fight AIDS, Tuberculosis, and Malaria (GFATM) Principal Recipients (Ministry of

Health (MOH) and Churches Health Association of Zambia (CHAZ), and Clinton Foundation. These drugs are placed in the MOH

central warehouse, Medical Stores Ltd. (MSL), for distribution to all accredited ART sites (governmental and non-governmental).

There are approximately 315 accredited ART sites in Zambia and more are being assessed for accreditation. In FY 2007 this

process was strengthened and further refined, to work with the increased number of ART sites that were added in to the system.

U.S. Zambia ART Track 1.0 partner Catholic Relief Services/AIDS Relief (CRS) was added to the system after successful

accreditation of sites, including four private sites.

Building on improvements made to the ARV supply chain in FY 2006, JSI/DELIVER continued its strong role in coordinating and

addressing ARV logistics system issues in FYs 2007 and 2008. Also in FY 2006, the U.S. Mission in Zambia strengthened the

logistics system in the Zambia Defense Force Medical Services (DFMS). This facilitated the inclusion of DFMS in the national

system enabling them to access drugs through MSL. In FY 2007 USAID/DELIVER focused on supporting the MOH in

coordinating ARV drug forecasting and procurement planning capacity at the central level, quantifying required ARV drugs,

reinforcing the standardization of ARV drug inventory control procedures at delivery sites, and developing and installing a software

tool for ART sites to collect and use for ordering ARV drugs which significantly reduced the time and effort required for ordering

and reporting.

In FY 2007, the MOH changed the first line ART regimen in Zambia for new patients to Tenofovir + Emtricitabine (FTC)/3TC +

Efavirenz or Nevirapine. Patients on the previously recommended first line therapy were to continue on the old regimen until either

treatment failure or toxicities occurred. The decision to change regimens followed concerns about toxicities such as peripheral

neuropathy, lipodystrophy and suspected lactic acidosis and was made after wide consultations on best practices by the National

ART treatment working group. Anemia was also commonly associated with AZT in Zambian patients. These toxicities sometimes

affected adherence to ART and deaths due to suspected lactic acidosis have occurred. The change to the Tenofovir based

regimen is expected to lead to better outcomes due to decreased toxicities and better adherence to therapy. The U.S. Mission in

Zambia is developing a public health evaluation to assess the cost effectiveness of Tenofovir based ART combination.

In FY 2008, the U.S. Mission in Zambia continued its strong collaboration with GRZ, GFATM, UNITAID/Clinton Foundation to

assist the national ART programs in fulfilling demand for ART services. On behalf of the U.S. Mission in Zambia, SCMS

purchased the following drugs: 3TC, AZT 100mg, LPV/r syrup, AZT/3TC, ddI 100mg, ddI 50mg, EFV 200mg, EFV 600mg, NFV

250mg, NLF LPV/r133/33 caps, NVP 200mg, and Tenofovir/Lamivudine. This will continue in FY 2009. Purchases may change: 1)

as additional ARV drugs become approved by the Food and Drug Administration (FDA) and registered in Zambia, 2) as GFATM

donations become solidified, 3) as Clinton Foundation ARV drug donations are scaled down; and 4) if GRZ changes the national

ARV treatment protocols. These specific ARV drugs, in conjunction with the ARV drugs procured by GRZ and GFATM, will go

directly to MSL where all accredited ART sites (GRZ, faith-based hospitals, NGOs, and work-place/private sector entities) have

access to these critical supplies. It is estimated that approximately two percent of the total SCMS budget will be used to procure

pediatric ARV drugs; this figure is based on the UNITAID/Clinton Foundation's commitment to provide all required pediatric first

line formulations during this time period.

As funding for FY 2009 is a straight-line of the FY 2008 level, the U.S. Mission in Zambia plans to spend $24M on drugs in FY

2009 unless needed additional funding becomes available. In addition, with Track 1.0 funds, CRS is planning to set aside

$100,000 as back up for purchasing drugs in case of a stock out from the national supply. As compared with FY 2007 when

several partners procured outside of the system, in FY 2008 all procurement was through the MSL. This will continue in FY 2009.

All partners will continue receiving their drugs from MSL through the GRZ system, a significant achievement made possible in part

by U.S. support. It is estimated that U.S. procurements, in combination with GFATM and Clinton Foundation purchases, will

enable Zambia to place 230,000 patients on ART by the end of 2009 (the MOH's target).

The biggest challenge with ARV drug procurement for national ART needs is the anticipated ARV drug procurement financing gap

in FYs 2009 and 2010. Two main factors drive the anticipated gap: 1) the increase in patients combined with a steady budget;

and 2) the change to the more expensive Tenofovir based regimen. PEPFAR I was to place 120,000 people on treatment by

2008. This goal has already by far been exceeded, supported by level funding with ever increasing demand. At current prices, the

Tenofovir based combination costs over $200 more per patient, which has a dramatic impact on the overall finances required.

Even if the cost of Tenofovir came down, with current funding levels and demand, the gap would remain. Discussions are

ongoing with GRZ for an increased budgetary allocation to ARV drugs. Yet based on current and projected GRZ funding in the

2009 budget, this will not significantly reduce the deficit. Another possible source of funding is the GFTAM. While the outcome of

Round 8 application, which includes some ARV drugs, is still pending, Zambia plans a Round 9 proposal focusing on treatment.

The national ARV drug logistics system and the quantification process will assist in achieving a sustainable national ART program

following intensive PEPFAR support.

Table 3.3.15:

Funding for Laboratory Infrastructure (HLAB): $500,000

ACTIVITY UNCHANGED FROM FY 2008.

This activity is linked to Centers for Disease Control and Prevention - Technical Assistance (CDC-TA

#3706.08), Chest Diseases Laboratory (CDL #3703.08), Unive3702.08), University Teaching Hospital (UTH

# 9798), EGPAF-CIDRZ (# 16956), Associated Public Health Laboratories (APHL), Ministry of health

laboratory Information System (MOH-LIS) in the laboratory infrastructure section.

This activity allows international laboratory experts to spend time in Zambia working side-by-side with

Zambian nationals to transfer laboratory technical skills rather than sending Zambian laboratory staff to the

United States or other countries for training. With the experts in-country, a larger target population for skills

transference is reached. The experts in -country are able to see, work in, and transfer skills relevant to the

Zambian laboratory environment and to identify and implement practical solutions and not just transferring

Western or developing country laboratory techniques to Zambia.

In FY 2007 this activity allowed one international laboratory expert to work in Zambia to provide technical

assistance to more than 150 laboratory technicians in five provinces. The laboratory technical experts

worked in-country with partners and CDC staff (including four CDC Zambian public health laboratory

technologists) to strengthen national sustainability for good laboratory practices, planning and quality

assurance on a daily basis for diagnosis, care, and treatment support.

The funds from FY 2008 contributed to support this laboratory expert to work with the Ministry of Health

(MOH), Department of Defense (DOD), CDC Zambian laboratory staff and other partners focusing on 1)

rapid HIV testing roll out planning and training, 2) strengthening skills and expanding quality assurance

programs for automated- and non-automate laboratory testing procedures such as CD4, hematology, and

chemistry for monitoring care and treatment support to persons on ARV and TB therapy as well as carry out

duties as described in FY 2007. In addition, the FY 2008 funds was also used to support a HIV virologist to

work with partners such as UTH, CIDRZ, TDRC, and CDC laboratory team to establish and strengthen

quality assurance program for early infant diagnosis within the country as well as drug resistance testing.

In FY 2009, this activity will support these two laboratory experts to enable them to continue to provide

technical assistance to the MOH, DOD, partners and CDC. While the first laboratory expert will continue

previously described activities, the second consultant in HIV virologist will work with the MOH, partners,

under the direction of CDC Chief for Laboratory Infrastructure and support program to establish and/or

strengthen an integrated national quality assurance program for laboratory testing services including HIV

rapid testing, CD4, hematology, chemistry, TB, malaria, and bacteriology. This activity provides support for

lodging, consultant fees, travel, training costs, needed supplies, and other costs related to work with the

MOH laboratory unit, and the national HIV/TB program in Zambia. Technical support from two international

experts brings expertise and provides efficient and sustainable human resource capacity building in local

laboratory personnel. Continuous onsite in-country training and monitoring will allow several laboratory staff

to expand technical expertise as well as in management, leadership and problem solving skills in both

provincial and districts laboratories within Zambia.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15514

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15514 3704.08 HHS/Centers for Comforce 7169 3011.08 Comforce $550,000

Disease Control &

Prevention

8996 3704.07 HHS/Centers for Comforce 5002 3011.07 Comforce $550,000

Disease Control &

Prevention

3704 3704.06 HHS/Centers for Comforce 3011 3011.06 ORISE Lab $164,322

Disease Control &

Prevention

Emphasis Areas

Health-related Wraparound Programs

* TB

Workplace Programs

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $400,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.16:

Funding for Strategic Information (HVSI): $300,000

The funding level for this activity in FY 2008 will remain the same as in FY 2007. Only minor narrative

updates have been made to highlight progress and achievements.

This activity relates to EGPAF SI, JHPIEGO SI, AIDSRelief - Catholic Relief Services (CRS), Ministry of

Health (MOH), and Technical Assistance/Centers for Disease Control and Prevention (CDC) and Zambia

National Blood Transfusion Service (ZNBTS).

To support the continued transition of software upgrades and development in 2008 to in-country talent, the

United States Government (USG) will continue to provide support for the ‘lead' professional

programmer/developer who is working closely with the SmartCare team on-location in Zambia to continue

bringing skill levels of the Zambian team up to the level required to maintain and adapt the software in the

future. In addition to this lead staff, the Centers for Disease Control and Prevention (CDC) strategic

information (SI) section will continue to support a national hire as an understudy. The purpose of having

these two SI staff in-house is for closer monitoring and evaluation of their capability and contribution, and to

make it easier to provide close guidance for the next phase of the project as the Ministry of Health (MOH)

assumes more leadership in a new technical area.

The intent for the ‘national hire' developer is to provide an option for a longer term and lower cost technical

bridge between the US-based technical expertise that jump-started the project, and the locally sustainable

ownership of the technology. This provides CDC an alternative method of placing essential software talent

at the disposal of the ministry; this is particularly crucial due to the recent Ministry reorganization and

technical gaps.

The high end technical professional possesses experience in developing clinical software applications,

including Electronic Health Records (EHR), and will be employed no more than two years (thired in 2007).

This lead professional works daily with Zambian colleagues to ensure transparent and shared engineering

of the system as it being deployed.

This activity provides a critical one to two year bridging capacity, while the US based developers who gave

the project its initial jump start are tapered down to small contributions and backup roles for what is

becoming the Zambian EHR (SmartCare). August 31, 2006, the Ministry held a high level meeting to

announce to all the Cooperating Partners the plan to deploy SmartCare nationwide. In August of 2007 they

announce the MOH intention to deploy the system to 900 sites in less than two years - with support from

partners, most specifically PEPFAR. They were able to announce that the latest consensus revision of the

ART software ‘forms' were entirely developed in Zambia. However there remain some challenging technical

areas yet to be mastered by the in-country team, despite the tremendous success of the project concept at

a political level and deployment level.

Targets set for this activity cover a period ending September 30, 2009.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15515

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15515 9692.08 HHS/Centers for Comforce 7169 3011.08 Comforce $300,000

Disease Control &

Prevention

9692 9692.07 HHS/Centers for Comforce 5002 3011.07 Comforce $300,000

Disease Control &

Prevention

Table 3.3.17:

Cross Cutting Budget Categories and Known Amounts Total: $685,000
Human Resources for Health $150,000
Human Resources for Health $135,000
Human Resources for Health $400,000