Detailed Mechanism Funding and Narrative

Years of mechanism: 2008 2009

Details for Mechanism ID: 7207
Country/Region: Uganda
Year: 2009
Main Partner: To Be Determined
Main Partner Program: NA
Organizational Type: Implementing Agency
Funding Agency: USAID
Total Funding: $0

Funding for Biomedical Prevention: Prevention of Mother to Child Transmission (MTCT): $0

The USG has been supporting provision of ART services in Uganda through the Joint Clinical research

Center (JCRC) since 2003. Today, JCRC is the leading provider of ART in Uganda with over 40,000

patients, providing ART in 51 static and 25 outreach sites across the country. The static and outreach sites

are supported through six regional centers of excellence (RCE) located in Jinja, Mbale, Gulu, Mbarara,

Kabale and Fort Portal.

In FY 2008, JCRC initiated treatment to over 10,000 new clients bringing the total number of clients on ART

to over 40,000. Currently JCRC is the largest single provider of pediatric ART with over 7,600 children

accessing treatment. In FY 2008, over 4,000 health workers were trained in clinical care, laboratory

services, logistics, community mobilization and pediatric HIV/AIDS care.

The USAID cooperative agreement with JCRC has been extended to September 2009. USAID/PEPFAR will

continue to support HIV/AIDS prevention, care and support activities through indigenous partnerships,

which demonstrate competency and leadership in respective technical areas. These partnerships are

envisaged to continue as mechanisms for building local partnership, response, ownership and sustainability.

While doing so, USAID envisions moving from sole sourcing to open competition among indigenous

partners. Competition will prompt local partners on the need to be competitive, and on the requirement to

develop their own capacity in designing and developing high quality and competitive proposals and

programs. USAID will award the new agreement by March 2009. This will ensure smooth transition

between the current JCRC program and the TBD mechanism.

In FY 2009 the major focus of the activity will be to ensure the continuity of life saving services, a smooth

transition and capacity building of 11 regional referral hospitals and expansion of district wide HIV/AIDS

care and treatment services in 40 facilities located in the 11 districts hosting the regional referral hospitals.

Specific activities will include: training health workers, strengthening and mentoring regional hospitals,

districts, private sector including faith-based institutions and other anti-retroviral therapy (ART) providers to

scale-up ART services district-wide, and infrastructure development for increased clinical space for ART in

rural health centers and improved laboratory infrastructure and services for diagnosis and monitoring of

treatment for tuberculosis(TB) and HIV. The program will train physicians and non-physicians to provide

ART services. The program will also support groups of People Living with HIV/AIDS (PHAs) to provide

services as expert clients in the health facilities and in the community. PHAs will facilitate referrals and

linkages between facility-based and community-based care, ART literacy, food and nutrition support,

support for adherence to anti-retrovirals (ARVs), counseling for prevention with positives and linkages to

basic preventive package and wrap-around services.

In an effort to integrate delivery of interventions for Prevention of Mother to child Transmission (PMTCT)

within maternal and child health services (MCH), the TREAT program will scale-up the use of highly active

anti-retroviral (ARVs) for treating pregnant women and preventing HIV-infection in infants in 55 supported

sites. The program will provide HIV/AIDS Counseling and Testing (HCT) and CD4+ cell measurement

services to at least 10,000 HIV-positive pregnant women in 55 sites to determine anti-retroviral therapy

(ART) eligibility and provide ART to those eligible. It is estimated that 30 percent of these women will

receive ART services.

The program will provide support and training to other USG-supported program to integrate CD4+ cell

measurement and Early Infant Diagnosis using DNA-PCR in the essential package for pregnant women and

setup referral networks to ensure that health facilities without CD4+ cell measurement facilities send

samples to referral laboratories.

In addition to training staff in MCH services to provide ART, the program will procure and provide ARVs to

antenatal clinics in 55 sites. The program will also ensure that AZT and Nevirapine for infants is available in

the 55 MCH sites.

It is estimated that 400 HIV-positive pregnant women with CD4 cell count below 350cells/mm³ will receive

ART while 700 not yet eligible for ART will receive a course of highly effective ARVs for prevention of HIV

infection in infants. All the 400 HIV-exposed infants will receive a seven-day course of Zidovudine (AZT)

and Nevirapine. The program will follow the revised Ministry of Health protocol for PMTCT and the WHO

recommendations for ARV drugs for treating pregnant women and preventing HIV-infection in infants in

Resource-limited setting. It is anticipated that through this activity, PMTCT using single dose Nevirapine will

be reduced to an absolute minimum in the supported sites.

The program will link with the President's Malaria Initiative (PMI) to provide Intermittent Preventive Therapy

for malaria in pregnancy using either daily Cotrimoxazole or three-doses of sulfadoxine-pyrimethamine and

the distribution of Insecticide Treated Mosquito nets to pregnant mothers. All women diagnosed to be HIV-

positive will be screened for tuberculosis (TB) and receive nutritional counseling and education including

support for infant feeding. All women eligible will receive Cotrimoxazole prophylaxis.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15894

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15894 15894.08 U.S. Agency for Joint Clinical 7207 7207.08 TREAT $300,000

International Research Center, (Timetable for

Development Uganda Regional

Expansion of

ART)

Emphasis Areas

Health-related Wraparound Programs

* Family Planning

* Malaria (PMI)

* TB

Military Populations

Refugees/Internally Displaced Persons

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.01:

Funding for Care: Adult Care and Support (HBHC): $0

The USG has been supporting the provision of ART services in Uganda through the Joint Clinical research

Center (JCRC) since 2003. Today, JCRC is the leading provider of ART in Uganda with over 40,000

patients, providing ART in 51 static and 25 outreach sites across the country. The static and outreach sites

are supported through six regional centers of excellence (RCE) located in Jinja, Mbale, Gulu, Mbarara,

Kabale and Fort Portal.

In FY 2008, JCRC initiated treatment to over 10,000 new clients bringing the total number of clients on ART

to over 40,000. Currently JCRC is the largest single provider of pediatric ART with over 7,600 children

accessing treatment. In FY 2008, over 4,000 health workers were trained in clinical care, laboratory

services, logistics, community mobilization and pediatric HIV/AIDS care.

The USAID cooperative agreement with JCRC has been extended to September 2009. USAID/PEPFAR will

continue to support HIV/AIDS prevention, care and support activities through indigenous partnerships which

demonstrated competency and leadership in respective technical areas. These partnerships are envisaged

to continue as mechanisms for building local partnership, response, ownership and sustainability. While

doing so USAID envisions moving from sole sourcing to open competition among indigenous partners.

Competition will prompt local partners on the need to be competitive and the requirement to develop their

own capacity in designing and developing high quality and competitive proposals and programs. USAID will

award the new agreement by March 2009. This will ensure smooth transition between the current JCRC

program and the follow-on mechanism.

In FY 2009 the major focus of the activity will be to ensure continuity of life saving services, smooth

transition and capacity building of the 11 regional referral hospital and expansion of district wide HIV/AIDS

care and treatment services in 40 facilities located in the 11 districts hosting the regional referral hospitals.

Specific activities will include: training health workers, strengthening and mentoring regional hospitals,

districts, private sector including faith-based institutions and other anti-retroviral therapy (ART) providers to

scale-up ART services district-wide, and infrastructure development for increased clinical space for ART in

rural health centers and improved laboratory infrastructure and services for diagnosis and monitoring of

treatment for tuberculosis(TB) and HIV. The program will train physicians and non-physicians to provide

ART services. The program will also support groups of People Living with HIV/AIDS (PHAs) to provide

services as expert clients in the health facilities and in the community. PHAs will facilitate referrals and

linkages between facility-based and community-based care, ART literacy, food and nutrition support,

support for adherence to anti-retrovirals (ARVs), counseling for prevention with positives and linkages to

basic preventive package and wrap-around services.

In the selected 11 focus districts, 11 regional referral hospitals and over 40 sites (district hospitals and

HCIVs), the program will support infrastructure development for ART services and build the capacity of the

Directorate of Health Services to manage ART services in the district. The program will provide technical

and financial support for districts to carry out quarterly support supervision activities. The program will

ensure consistent availability of care and treatment services of patients currently under JCRC mechanism.

Critical emerging issues like adherence, surveillance for resistance, Infant Diagnosis using DNA-PCR and

screening of patients under palliative care for ART eligibility will be supported. The program will provide

financial support in the form of grants to Civil society organizations and Networks of PHAs to carry out

activities that support improved ART literacy, adherence, patient tracking, prevention with positives and

linkages to wrap around services.

A key area of focus for this program will be support for the scale-up of access to ART for pregnant women

by ensuring that ARVs are available in the ante-natal clinics and that staff in the antenatal clinics are trained

to counsel, initiate and manage ART in pregnant women. The program will also work closely with the

maternity ward and pediatrics unit to identify HIV-exposed and infected children, provide infant-diagnostic

services and provide care and ARVs for those that are eligible.

In the selected 11 focus districts, 11 regional referral hospitals and over 40 sites, the program will provide

care and support services to 40,000 clients not yet eligible for ART. This brings the total number of patients

under care, including those on ART, to over 85,000. The program will provide clinical care services

including diagnosis and treatment of opportunistic infections (OIs), nutritional assessment and counseling,

psychosocial support and screening for ART eligibility. Patients under palliative care will be screened for

tuberculosis and those diagnosed with TB will receive treatment. The program will provide a comprehensive

preventive basic care package to the 40,000 clients under care.

The program will train and support 120 expert clients and community volunteers from 60 groups of People

Living with HIV/AIDS to facilitate referrals and linkages between facility-based and community based care.

The groups will facilitate referrals to wrap around services available in the communities. 350 health workers

will be trained to provide palliative care services.

The program will scale-up TB/HIV integration activities including setting facility infection control procedures

in facilities supported, provider-initiated counseling and testing for TB-registered clients and ensuring

referral and retrieval referrals between TB and HIV clinics and services.

New/Continuing Activity: Continuing Activity

Continuing Activity: 16008

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16008 16008.08 U.S. Agency for Joint Clinical 7207 7207.08 TREAT $340,000

International Research Center, (Timetable for

Development Uganda Regional

Expansion of

ART)

Emphasis Areas

Military Populations

Refugees/Internally Displaced Persons

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Estimated amount of funding that is planned for Food and Nutrition: Policy, Tools

and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.08:

Funding for Treatment: Adult Treatment (HTXS): $0

The USG has been supporting the provision of ART services in Uganda through the Joint Clinical research

Center (JCRC) since 2003. Today, JCRC is the leading provider of ART in Uganda with over 40,000

patients, providing ART in 51 static and 25 outreach sites across the country. The static and outreach sites

are supported through six regional centers of excellence (RCE) located in Jinja, Mbale, Gulu, Mbarara,

Kabale and Fort Portal.

In FY 2008, JCRC initiated treatment to over 10,000 new clients bringing the total number of clients on ART

to over 40,000. Currently JCRC is the largest single provider of pediatric ART with over 7,600 children

accessing treatment. In FY 2008, over 4,000 health workers were trained in clinical care, laboratory

services, logistics, community mobilization and pediatric HIV/AIDS care.

The USAID cooperative agreement with JCRC has been extended to September 2009. USAID/PEPFAR will

continue to support HIV/AIDS prevention, care and support activities through indigenous partnerships which

demonstrated competency and leadership in respective technical areas. These partnerships are envisaged

to continue as mechanisms for building local partnership, response, ownership and sustainability. While

doing so USAID envisions moving from sole sourcing to open competition among indigenous partners.

Competition will prompt local partners on the need to be competitive and the requirement to develop their

own capacity in designing and developing high quality and competitive proposals and programs. USAID will

award the new agreement by March 2009. This will ensure smooth transition between the current JCRC

program and the follow-on mechanism.

In FY 2009 the major focus of the activity will be to ensure continuity of life saving services, smooth

transition and capacity building of the 11 regional referral hospital and expansion of district wide HIV/AIDS

care and treatment services in 40 facilities located in the 11 districts hosting the regional referral hospitals.

Specific activities will include: training health workers, strengthening and mentoring regional hospitals,

districts, private sector including faith-based institutions and other anti-retroviral therapy (ART) providers to

scale-up ART services district-wide, and infrastructure development for increased clinical space for ART in

rural health centers and improved laboratory infrastructure and services for diagnosis and monitoring of

treatment for tuberculosis(TB) and HIV. The program will train physicians and non-physicians to provide

ART services. The program will also support groups of People Living with HIV/AIDS (PHAs) to provide

services as expert clients in the health facilities and in the community. PHAs will facilitate referrals and

linkages between facility-based and community-based care, ART literacy, food and nutrition support,

support for adherence to anti-retrovirals (ARVs), counseling for prevention with positives and linkages to

basic preventive package and wrap-around services.

In the selected 11 focus districts, 11 regional referral hospitals and over 40 sites (district hospitals and

HCIVs), the program will support infrastructure development for ART services and build the capacity of the

Directorate of Health Services to manage ART services in the district. The program will provide technical

and financial support for districts to carry out quarterly support supervision activities. The program will

ensure consistent availability of care and treatment services of patients currently under JCRC mechanism.

Critical emerging issues like adherence, surveillance for resistance, Infant Diagnosis using DNA-PCR and

screening of patients under palliative care for ART eligibility will be supported. The program will provide

financial support in the form of grants to Civil society organizations and Networks of PHAs to carry out

activities that support improved ART literacy, adherence, patient tracking, prevention with positives and

linkages to wrap around services.

A key area of focus for this program will be support for the scale-up of access to ART for pregnant women

by ensuring that ARVs are available in the ante-natal clinics and that staff in the antenatal clinics are trained

to counsel, initiate and manage ART in pregnant women. The program will also work closely with the

maternity ward and pediatrics unit to identify HIV-exposed and infected children, provide infant-diagnostic

services and provide care and ARVs for those that are eligible.

In the selected 11 focus districts, 11 regional referral hospitals and over 40 sites, the program will provide

care and support services to 40,000 clients not yet eligible for ART. This brings the total number of patients

under care, including those on ART, to over 85,000. The program will provide clinical care services

including diagnosis and treatment of opportunistic infections (OIs), nutritional assessment and counseling,

psychosocial support and screening for ART eligibility. Patients under palliative care will be screened for

tuberculosis and those diagnosed with TB will receive treatment. The program will provide a comprehensive

preventive basic care package to the 40,000 clients under care.

The program will train and support 120 expert clients and community volunteers from 60 groups of People

Living with HIV/AIDS to facilitate referrals and linkages between facility-based and community based care.

The groups will facilitate referrals to wrap around services available in the communities. 350 health workers

will be trained to provide palliative care services.

The program will scale-up TB/HIV integration activities including setting facility infection control procedures

in facilities supported, provider-initiated counseling and testing for TB-registered clients and ensuring

referral and retrieval referrals between TB and HIV clinics and services.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15791

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15791 15791.08 U.S. Agency for Joint Clinical 7207 7207.08 TREAT $4,800,000

International Research Center, (Timetable for

Development Uganda Regional

Expansion of

ART)

Emphasis Areas

Military Populations

Refugees/Internally Displaced Persons

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Estimated amount of funding that is planned for Food and Nutrition: Policy, Tools

and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.09:

Funding for Care: Pediatric Care and Support (PDCS): $0

The USG has been supporting the provision of ART services in Uganda through the Joint Clinical research

Center (JCRC) since 2003. Today, JCRC is the leading provider of ART in Uganda with over 40,000

patients, providing ART in 51 static and 25 outreach sites across the country. The static and outreach sites

are supported through six regional centers of excellence (RCE) located in Jinja, Mbale, Gulu, Mbarara,

Kabale and Fort Portal.

In FY 2008, JCRC initiated treatment to over 10,000 new clients bringing the total number of clients on ART

to over 40,000. Currently JCRC is the largest single provider of pediatric ART with over 7,600 children

accessing treatment. In FY 2008, over 4,000 health workers were trained in clinical care, laboratory

services, logistics, community mobilization and pediatric HIV/AIDS care.

The USAID cooperative agreement with JCRC has been extended to September 2009. USAID/PEPFAR will

continue to support HIV/AIDS prevention, care and support activities through indigenous partnerships which

demonstrated competency and leadership in respective technical areas. These partnerships are envisaged

to continue as mechanisms for building local partnership, response, ownership and sustainability. While

doing so USAID envisions moving from sole sourcing to open competition among indigenous partners.

Competition will prompt local partners on the need to be competitive, and on the requirement to develop

their own capacity in designing and developing high quality and competitive proposals and programs.

USAID will award the new Cooperative Agreement by March 2009. This will ensure smooth transition

between the current JCRC program and the TBD mechanism.

In FY 2009 the major focus of the activity will be to ensure continuity of life saving care and treatment

services, smooth transition and capacity building in the 11 regional referral hospitals and expansion of

district wide HIV/AIDS care and treatment services in 40 facilities located in the 11 districts hosting the

regional referral hospitals.

Specific activities will include: training health workers, strengthening and mentoring regional hospitals,

districts, private sector including faith-based institutions and other anti-retroviral therapy (ART) providers to

scale-up ART services district-wide, and infrastructure development for increased clinical space for ART in

rural health centers and improved laboratory infrastructure and services for diagnosis and monitoring of

treatment for tuberculosis(TB) and HIV. The program will train physicians and non-physicians to provide

Pediatric care and treatment services. The program will also support groups of People Living with HIV/AIDS

(PHAs) to provide services as expert clients in the health facilities and in the community. PHAs will facilitate

referrals and linkages between facility-based and community-based care, utilization of pediatric care and

treatment services, growth monitoring, food and nutrition support, support for adherence to anti-retrovirals

(ARVs), counseling for pediatric HIV-positive patients and linkages to basic preventive package and wrap-

around services.

In the selected 11 focus districts, 11 regional referral hospitals and over 40 sites, the program will support

infrastructure development for pediatric care and treatment services and build capacity of the Directorate of

Health Services to scale-up linkages between PMTCT and pediatric care and treatment in the district. It is

estimated that a total of 11,000 children will receive care and 5,000 will be initiated on treatment.

Critical emerging issues like adherence, surveillance for resistance, Infant Diagnosis using DNA-PCR and

screening of patients under palliative care for ART eligibility will be supported. The program will provide

financial support in form of grants to Civil society organizations and Networks of PHAs to carry out activities

that support improved ART literacy, adherence, patient tracking, prevention with positives and linkages to

wrap around services.

A key area of focus for this program will be support for the scale-up of access to ART for pregnant women

by ensuring that ARVs are available in the ante-natal clinics and that staff in the antenatal clinics are trained

to counsel, initiate and manage ART in pregnant women and, linkages between pregnant women and

pediatric care are strengthened. The program will also work closely with the maternity ward and pediatrics

unit to identify HIV-exposed and infected children, provide infant-diagnostic services and provide care and

ARVs for those that are eligible.

New/Continuing Activity: Continuing Activity

Continuing Activity: 16008

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16008 16008.08 U.S. Agency for Joint Clinical 7207 7207.08 TREAT $340,000

International Research Center, (Timetable for

Development Uganda Regional

Expansion of

ART)

Table 3.3.10:

Funding for Treatment: Pediatric Treatment (PDTX): $0

The USG has been supporting the provision of ART services in Uganda through the Joint Clinical research

Center (JCRC) since 2003. Today, JCRC is the leading provider of ART in Uganda with over 40,000

patients, providing ART in 51 static and 25 outreach sites across the country. The static and outreach sites

are supported through six regional centers of excellence (RCE) located in Jinja, Mbale, Gulu, Mbarara,

Kabale and Fort Portal.

In FY 2008, JCRC initiated treatment to over 10,000 new clients bringing the total number of clients on ART

to over 40,000. Currently JCRC is the largest single provider of pediatric ART with over 7,600 children

accessing treatment. In FY 2008, over 4,000 health workers were trained in clinical care, laboratory

services, logistics, community mobilization and pediatric HIV/AIDS care.

The USAID cooperative agreement with JCRC has been extended to September 2009. USAID/PEPFAR will

continue to support HIV/AIDS prevention, care and support activities through indigenous partnerships which

demonstrated competency and leadership in respective technical areas. These partnerships are envisaged

to continue as mechanisms for building local partnership, response, ownership and sustainability. While

doing so USAID envisions moving from sole sourcing to open competition among indigenous partners.

Competition will prompt local partners on the need to be competitive, and on the requirement to develop

their own capacity in designing and developing high quality and competitive proposals and programs.

USAID will award the new Cooperative Agreement by March 2009. This will ensure smooth transition

between the current JCRC program and the TBD mechanism.

In FY 2009 the major focus of the activity will be to ensure continuity of life saving care and treatment

services, smooth transition and capacity building in the 11 regional referral hospitals and expansion of

district wide HIV/AIDS care and treatment services in 40 facilities located in the 11 districts hosting the

regional referral hospitals. Specific activities will include: training health workers, strengthening and

mentoring regional hospitals, districts, private sector including faith-based institutions and other anti-

retroviral therapy (ART) providers to scale-up ART services district-wide, and infrastructure development for

increased clinical space for ART in rural health centers and improved laboratory infrastructure and services

for diagnosis and monitoring of treatment for tuberculosis(TB) and HIV. The program will train physicians

and non-physicians to provide Pediatric care and treatment services. The program will also support groups

of People Living with HIV/AIDS (PHAs) to provide services as expert clients in the health facilities and in the

community. PHAs will facilitate referrals and linkages between facility-based and community-based care,

utilization of pediatric care and treatment services, growth monitoring, food and nutrition support, support for

adherence to anti-retrovirals (ARVs), counseling for pediatric HIV-positive patients and linkages to basic

preventive package and wrap-around services.

In the selected 11 focus districts, 11 regional referral hospitals and over 40 sites, the program will support

infrastructure development for pediatric care and treatment services and build capacity of the Directorate of

Health Services to scale-up linkages between PMTCT and pediatric care and treatment in the district. It is

estimated that a total of 11,000 children will receive care and 5,000 will be initiated on treatment.

Critical emerging issues like adherence, surveillance for resistance, Infant Diagnosis using DNA-PCR and

screening of patients under palliative care for ART eligibility will be supported. The program will provide

financial support in form of grants to Civil society organizations and Networks of PHAs to carry out activities

that support improved ART literacy, adherence, patient tracking, prevention with positives and linkages to

wrap around services.

A key area of focus for this program will be support for the scale-up of access to ART for pregnant women

by ensuring that ARVs are available in the ante-natal clinics and that staff in the antenatal clinics are trained

to counsel, initiate and manage ART in pregnant women and, linkages between pregnant women and

pediatric care are strengthened. The program will also work closely with the maternity ward and pediatrics

unit to identify HIV-exposed and infected children, provide infant-diagnostic services and provide care and

ARVs for those that are eligible.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15791

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15791 15791.08 U.S. Agency for Joint Clinical 7207 7207.08 TREAT $4,800,000

International Research Center, (Timetable for

Development Uganda Regional

Expansion of

ART)

Emphasis Areas

Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Estimated amount of funding that is planned for Food and Nutrition: Policy, Tools

and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.11:

Funding for Care: TB/HIV (HVTB): $0

The USG has been supporting provision of ART services in Uganda through the Joint Clinical research

Center (JCRC) since 2003. Today, JCRC is the leading provider of ART in Uganda with over 40,000

patients, providing ART in 51 static and 25 outreach sites across the country. The static and outreach sites

are supported through six regional centers of excellence (RCE) located in Jinja, Mbale, Gulu, Mbarara,

Kabale and Fort Portal.

In FY 2008, JCRC initiated treatment to over 10,000 new clients bringing the total number of clients on ART

to over 40,000. Currently JCRC is the largest single provider of pediatric ART with over 7,600 children

accessing treatment. In FY 2008, over 4,000 health workers were trained in clinical care, laboratory

services, logistics, community mobilization and pediatric HIV/AIDS care. It has also identified and treated

700 TB/HIV co-infected patients and trained 150 health workers on TB/HIV collaborative activities. The

program is also expected to have provided anti-retroviral therapy to 500 TB/HIV co-infected clients by the

end of the FY 2008.

The USAID cooperative agreement with JCRC has been extended to September 2009. USAID/PEPFAR will

continue to support HIV/AIDS prevention, care and support activities through indigenous partnerships,

which demonstrate competency and leadership in respective technical areas. These partnerships are

envisaged to continue as mechanisms for building local partnership, response, ownership and sustainability.

While doing so, USAID envisions moving from sole sourcing to open competition among indigenous

partners. Competition will prompt local partners on the need to be competitive, and on the requirement to

develop their own capacity in designing and developing high quality and competitive proposals and

programs. During the extension phase JCRC will transition the majority of the sites beyond the nine

regional referral hospitals to the new USAID district based mechanisms, other PEPFAR partners who

overlap in the same facilities, and to the Ministry of Health (MOH). To ensure continuity of services, USAID

will award the new agreement by March 2009.

In FY 2009 the major focus of the activity is to ensure continuity of life saving services, smooth transition

and building capacity of nine regional referral hospitals. 1,000 new TB/HIV co-infected patients will be

identified, treated for TB and given cotrimoxazole prophylaxis. The program will implement infection control

procedures at all the nine regional referral hospitals.

The program will train and support 120 expert clients from 60 groups of People Living with HIV/AIDS to

facilitate referrals and linkages between facility-based and community based TB and HIV management. The

groups will facilitate referrals to wrap around services available in the communities. 100 health workers will

be trained to provide TB/HIV services. The program will scale-up TB/HIV integration activities including

setting facility infection control procedures in facilities supported, provider-initiated counseling and testing

for TB-registered clients and ensuring referral and retrieval referrals between TB and HIV clinics and

services. The activity will closely work with the MOH national TB reference laboratory and the National

Tuberculosis Control Program for diagnosis and referral of Multi-Drug Resistant Tuberculosis.

New/Continuing Activity: Continuing Activity

Continuing Activity: 16007

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16007 16007.08 U.S. Agency for Joint Clinical 7207 7207.08 TREAT $225,000

International Research Center, (Timetable for

Development Uganda Regional

Expansion of

ART)

Emphasis Areas

Military Populations

Refugees/Internally Displaced Persons

Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.12:

Funding for Treatment: ARV Drugs (HTXD): $0

The USG has been supporting the provision of ART services in Uganda through the Joint Clinical research

Center (JCRC) since 2003. Today, JCRC is the leading provider of ART in Uganda with over 40,000

patients, providing ART in 51 static and 25 outreach sites across the country. The static and outreach sites

are supported through six regional centers of excellence (RCE) located in Jinja, Mbale, Gulu, Mbarara,

Kabale and Fort Portal.

In FY 2008, JCRC initiated treatment to over 10,000 new clients bringing the total number of clients on ART

to over 40,000. Currently JCRC is the largest single provider of pediatric ART with over 7,600 children

accessing treatment. In FY 2008, over 4,000 health workers were trained in clinical care, laboratory

services, logistics, community mobilization and pediatric HIV/AIDS care.

The USAID cooperative agreement with JCRC has been extended to September 2009. USAID/PEPFAR will

continue to support HIV/AIDS prevention, care and support activities through indigenous partnerships which

demonstrated competency and leadership in respective technical areas. During the extension phase JCRC

will transition majority of the sites beyond the nine regional referral hospitals, to the new USAID district

based mechanisms, other PEPFAR partners who overlap in the same facilities, and to the Ministry of Health

(MOH). To ensure continuity of services USAID will award the TBD new mechanism by March 2009, this will

ensure smooth transition between the current JCRC program and the TBD mechanism.

In FY 2009 the major focus of the activity is to ensure continuity of life saving services, smooth transition

and building capacity of nine regional referral hospitals. The program will provide training of over 200 health

workers in ARV logistics and procurement focusing on forecasting, warehouse management and distribution

of ARVs.

The program will procure ARVs to cater for over 30,000 patients on first line treatment and 1500 on second

line. The program will also procure a buffer stock to respond to emergency stock-outs of ARV in the public

health sites. The program will introduce a pharmacy dispensing tool to capture and report on clients

accessing ARVs, track patients and report on treatment outcomes.

A key area of focus for this program will be support for the scale-up of access to ART for pregnant women

by ensuring that ARVs are available in the ante-natal clinics and that staff in the antenatal clinics are trained

to counsel, initiate and manage ART in pregnant women. The program will also work closely with the

maternity ward and pediatrics unit to identify HIV-exposed and infected children, provide infant-diagnostic

services and provide care and ARVs for those that are eligible.

In FY 2009, the program will continue to support the Department of Defense (DOD) ART programs through

Walter Reed in Kayunga district and Uganda People Defense Forces (UPDF) in Gulu, providing ART to

2,000 additional clients.

In conjunction with Supply Chain Management Systems (SCMS), the program will continue to explore the

introduction of the Smart Card and an ART Dispensing Tool in all supported ART sites to improve patient

tracking.

New/Continuing Activity: Continuing Activity

Continuing Activity: 16008

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16008 16008.08 U.S. Agency for Joint Clinical 7207 7207.08 TREAT $340,000

International Research Center, (Timetable for

Development Uganda Regional

Expansion of

ART)

Emphasis Areas

Military Populations

Refugees/Internally Displaced Persons

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Estimated amount of funding that is planned for Food and Nutrition: Policy, Tools

and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.15:

Funding for Laboratory Infrastructure (HLAB): $0

The USG has been supporting the provision of ART services in Uganda through the Joint Clinical research

Center (JCRC) since 2003. Today, JCRC is the leading provider of ART in Uganda with over 40,000

patients, providing ART in 51 static and 25 outreach sites across the country. The static and outreach sites

are supported through six regional centers of excellence (RCE) located in Jinja, Mbale, Gulu, Mbarara,

Kabale and Fort Portal. In FY 2008, JCRC initiated treatment to over 10,000 new clients bringing the total

number of clients on ART to over 40,000. Currently JCRC is the largest single provider of pediatric ART with

over 7,600 children accessing treatment. In FY 2008, over 4,000 health workers were trained in clinical

care, laboratory services, logistics, community mobilization and pediatric HIV/AIDS care.

Between October 2007 and June 2008, JCRC conducted 216,837 CD4 tests, 15000 DNA PCR tests, and

204,946 chemistry tests through six regional centers of excellences and JCRC centers in Kampala. JCRC is

the lead partner in providing laboratory support for the Ministry of Health (MOH) EID program; in providing

viral load and CD4 tests for monitoring treatment response and drug failure; and DNA sequencing for HIV

Drug resistance testing. The JCRC advanced laboratory is being used as major referral center for Uganda

and several African countries in the Great Lakes Region and reports to the national HIVDR Coordinating

Center at UVRI.

The cooperative agreement with JCRC has been extended to September 2009 and PEPFAR will continue

to support HIV/AIDS prevention, care and support activities through indigenous partnerships which have

demonstrated competency and leadership in respective technical areas. During the extension phase, JCRC

will transition the majority of the sites beyond the eleven regional referral hospitals to the new district-based

mechanism, other PEPFAR partners who overlap in the same facilities and to MOH. To ensure continuity of

services, the new mechanism will be awarded by June 2009 to ensure a smooth transition between the

current JCRC program and the TBD mechanism.

With more that 140,000 Ugandans on ART and as PEPFAR transitions from an emergency phase to a

sustainable program, it is imperative to address quality issues through regular CD4+ monitoring of patient

pre-ART and ART phase, annual viral load tests for patients on ART to monitor treatment responses; there

is also a need to rapidly increase access to DNA-PCR for early infant diagnosis. Through the TBD

mechanism USG will continue to support access to early infant diagnosis. In FY 2009, the program will

provide support to nine regional hospital laboratories to provide services for improved laboratory testing for

diagnosis of HIV infection and other opportunistic infections and for monitoring patients during care and

treatment. The program will support the establishment of effective laboratory networks in districts hosting

regional referral hospitals. The program will build the capacity of the district hospitals to provide level

appropriate laboratory support to lower health centers (HCIV and HCIII) through referral testing and support

supervision; in this JCRC will work closely with the MOH Central Public Health Laboratory. The program will

build capacity of regional referral hospitals to provide advanced HIV diseases monitoring services in a

consistent manner. The program receives reagents for EID from the Clinton Foundation, a donation to

MOH.

Additional resources are required in the subsequent fiscal years for this activity to achieve the objectives

highlighted above and to continue to provide the services that are being provided by JCRC including

supporting MOH, PEPFAR and non-PEPFAR partners in CD4+ counting, serum chemistries and

hematology, DNA and RNA PCR. The need for such lab services will increase exponentially with the rapid

scale up of ART services and as the MOH plans to link more service outlets to the EID network which is

mainly serviced through JCRC laboratories.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15914

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15914 15914.08 U.S. Agency for Joint Clinical 7207 7207.08 TREAT $1,400,000

International Research Center, (Timetable for

Development Uganda Regional

Expansion of

ART)

Emphasis Areas

Health-related Wraparound Programs

* TB

Military Populations

Refugees/Internally Displaced Persons

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.16: