Detailed Mechanism Funding and Narrative

Years of mechanism: 2008 2009

Details for Mechanism ID: 1107
Country/Region: Uganda
Year: 2008
Main Partner: Makerere University
Main Partner Program: School of Medicine
Organizational Type: NGO
Funding Agency: HHS/CDC
Total Funding: $13,517,941

Funding for Sexual Prevention: Abstinence/Be Faithful (HVAB): $330,000

Makerere University Faculty of Medicine was awarded a cooperative agreement titled "Provision of routine

HIV testing, counseling, basic care and antiretroviral therapy at teaching hospitals in the Republic of

Uganda" in 2004. The program named Mulago-Mbarara Teaching Hospitals' Joint AIDS Program (MJAP)

implements HIV/AIDS services in Uganda's two major teaching hospitals (Mulago and Mbarara) and their

catchment areas in close collaboration with the national programs run by the Ministry of Health (MOH).

MJAP also collaborates with the National tuberculosis and Leprosy Program (NTLP), and leverages

resources from the Global fund. MJAP provides comprehensive HIV/AIDS services including: 1) hospital-

based routine HIV testing and counseling (RTC), 2) palliative HIV/AIDS basic care, 3) integrated TB-HIV

diagnosis with treatment of TB-HIV co-infected patients, 4) ART and HIV post- exposure prophylaxis, 5)

family based care (FBC) which includes services for orphans and vulnerable children (OVC), in addition to

home-based HIV testing and prevention activities (HBHCT), and 6) capacity building for HIV prevention and

care through training of health care providers, laboratory strengthening, and establishment of satellite HIV

clinics. Mulago and Mbarara hospitals are public referral institutions with a mandate of training, service-

provision and research. Annually 3,000 health care providers are trained and about one million patients

seen in the two hospitals (500,000 outpatients and 130,000 inpatients for Mulago, and 300,000 in and

outpatients for Mbarara). Approximately 60% of medical admissions in both hospitals are because of HIV

infection and related complications. Within Mulago, MJAP works closely with the Infectious Diseases

Institute (IDI). IDI is an independent institute within the Faculty of Medicine of Makerere University with a

mission to build capacity for delivering sustainable, high-quality HIV/AIDS care, treatment and prevention in

Africa through training and research. At IDI health care providers from all over sub-Saharan Africa receive

training on HIV care and antiretroviral therapy (ART); people living with HIV (PHA) receive free clinical care

including ART at the Adult Infectious Diseases Clinic (AIDC) - the clinic is integral with Mulago teaching

hospital. The main HIV clinics in Mbarara and Mulago teaching hospitals are the Mbarara ISS (HIV) clinic

and AIDC, respectively; MJAP supports HIV care and treatment in both clinics. In FY 2005 and FY 2006

MJAP opened eight satellite clinics within the catchment areas of these two clinics due to the rapidly

increasing demand for HIV/AIDS care services; increasing the total number of treatment sites to 10. The

eight satellite clinics include Mulago hospital ISS clinic, Kawempe, Naguru, Kiswa and Kiruddu (under

Kampala City Council - KCC), Mbarara municipality clinic (under the Mbarara municipal council),

Bwizibwera health center IV (under MOH and Mbarara local government), and Mulago TB/HIV clinic, which

provides care for TB-HIV co-infected patients. The satellite clinic activities are implemented in collaboration

with several partners including KCC, Mbarara Municipal Council, IDI, Baylor-Paediatric Infectious Disease

Clinic (PIDC), Protection of Families against AIDS (PREFA), MOH, and other partners.

MJAP has been providing HIV prevention counseling including Abstinence and Be faithful (AB) counseling

through the HIV testing programs. Prevention counseling has also been integrated into the care and

treatment programs and OVC interventions (counseling and life skills training). In the RTC program, couple

testing is encouraged thus promoting disclosure and strengthening the B messages for concordant HIV

negative couples. ‘A' messages are encouraged for single youth below 20 years who are not yet sexually

active, among other interventions. Family members who are tested through the HBHCT program also

receive prevention counseling. Since November 2004, more than 5,000 children and youth have been

served through the MJAP counseling and testing, care and treatment programs. We have provided HIV

testing to over 3,000 couples, 19% of who were sero-discordant and 60% concordant negative.

In FY08 (April 2008 to March 2009), MJAP will strengthen the integration of AB activities into the existing

programs. Through HBHCT program, we will provide C&T to 2,000 households of index patients in care. We

anticipate reaching 3,000 children and youth through integration with the OVC, RTC and HBHCT

interventions. The AB activities will be integrated with other prevention to ensure a comprehensive HIV

prevention package. The A activities will primarily target children and single youth below 20 years but those

who are sexually active and/or married will also receive "B" messages and other prevention support

including condom use, as appropriate. These will be reached through the HIV testing programs and the

OVC services. The children will receive health education, counseling support and life skills training to

enable them make informed choices. The B activities will also be integrated with couples counseling (in

RTC and HBHCT) to encourage couples' HIV testing and mutual faithfulness to partners in concordant HIV

negative partnerships. We will also integrate the entire spectrum of prevention activities within the care and

treatment sites through the positive prevention and family planning interventions. The funding in this

category will support the integration and strengthening of existing AB activities, support for personnel

involved in AB activities, production and dissemination of information, education and communication

materials to support the AB programs, training of health care providers to integrate AB activities, improved

data collection, reporting, and M&E. Requirements for HIV testing will be covered under the CT budget.

Funding for Sexual Prevention: Other Sexual Prevention (HVOP): $560,000

Makerere University Faculty of Medicine was awarded a cooperative agreement titled "Provision of routine

HIV testing, counseling, basic care and antiretroviral therapy at teaching hospitals in the Republic of

Uganda" in 2004. The program named Mulago-Mbarara Teaching Hospitals' Joint AIDS Program (MJAP)

implements HIV/AIDS services in Uganda's two major teaching hospitals (Mulago and Mbarara) and their

catchment areas in close collaboration with the national programs run by the Ministry of Health (MOH).

MJAP also collaborates with the National tuberculosis and Leprosy Program (NTLP), and leverages

resources from the Global fund. MJAP provides comprehensive HIV/AIDS services including: 1) hospital-

based routine HIV testing and counseling (RTC), 2) palliative HIV/AIDS basic care, 3) integrated TB-HIV

diagnosis with treatment of TB-HIV co-infected patients, 4) ART and HIV post- exposure prophylaxis (PEP),

5) family based care (FBC) which includes services for orphans and vulnerable children (OVC), in addition

to home-based HIV testing and prevention activities (HBHCT), and 6) capacity building for HIV prevention

and care through training of health care providers, laboratory strengthening, and establishment of satellite

HIV clinics. Mulago and Mbarara hospitals are public referral institutions with a mandate of training, service

-provision and research. Annually 3,000 health care providers are trained and about one million patients

seen in the two hospitals (500,000 outpatients and 130,000 inpatients for Mulago, and 300,000 in and

outpatients for Mbarara). Approximately 60% of medical admissions in both hospitals are because of HIV

infection and related complications. Within Mulago, MJAP works closely with the Infectious Diseases

Institute (IDI). IDI is an independent institute within the Faculty of Medicine of Makerere University with a

mission to build capacity for delivering sustainable, high-quality HIV/AIDS care, treatment and prevention in

Africa through training and research. At IDI health care providers from all over sub-Saharan Africa receive

training on HIV care and antiretroviral therapy (ART); people living with HIV receive free clinical care

including ART at the Adult Infectious Diseases Clinic (AIDC) - the clinic is integral with Mulago teaching

hospital. The main HIV clinics in Mbarara and Mulago teaching hospitals are the Mbarara ISS (HIV) clinic

and AIDC, respectively; MJAP supports HIV care and treatment in both clinics. In FY 2005 and FY 2006

MJAP opened eight satellite clinics within the catchment areas of these two clinics due to the rapidly

increasing demand for HIV/AIDS care services; increasing the total number of treatment sites to 10. The

eight satellite clinics include Mulago hospital ISS clinic, Kawempe, Naguru, Kiswa and Kiruddu (under

Kampala City Council - KCC), Mbarara municipality clinic (under the Mbarara municipal council),

Bwizibwera health center IV (under MOH and Mbarara local government), and Mulago TB/HIV clinic, which

provides care for TB-HIV co-infected patients. The satellite clinic activities are implemented in collaboration

with several partners including KCC, Mbarara Municipal Council, IDI, Baylor-Paediatric Infectious Disease

Clinic (PIDC), Protection of Families against AIDS (PREFA), MOH, and other partners.

MJAP has integrated HIV prevention services into all the existing HIV counseling and testing, care and

treatment interventions. We have integrated prevention interventions at the following levels 1) prevention

counseling and couples counseling and testing in the RTC and HBHCT programs, 2) prevention with

positives counseling and support for all patients in the HIV/AIDS clinics, 3) Discordant couple clubs at two of

the HIV/AIDS clinics (one in Mulago and one in Mbarara), 4) Post-exposure prophylaxis for health care

providers, and 5) community prevention interventions in collaboration with the Mulago hospital sexually

transmitted diseases (STD) clinic, targeting high-risk groups. All patients receive health education and

prevention counseling, and are encouraged to disclose their HIV status to their partners. Partner HIV testing

is also provided at all the HIV/AIDS clinics and RTC wards. Through the HIV testing programs, we provide

couples' HIV testing, counseling support and condom provision for discordant couples. Since November

2004, the program has provided HIV testing to more than 3,000 couples, 19% of who were sero-discordant.

MJAP has also been engaged in activities to prevent HIV transmission in the health care setting. These

include training of health care providers in universal precautions, development and distribution of

information, education and communication materials, assessment and provision of post-exposure

prophylaxis PEP for health care providers following exposure to infectious materials. To date, we have

trained over 500 health care providers and provided PEP to more than 90 health care providers in Mulago

and Mbarara teaching hospitals. The STD unit in Mulago serves a significant number of high risk groups. In

collaboration with the STD unit, MJAP provides prevention services at the facility as well as the community

level. At the facility (STD clinic) patients receive prevention counseling and HIV testing through the RTC

program, screening and treatment of sexually transmitted infections. Within the community, the

interventions include prevention education and counseling for high-risk groups including bar attendants,

commercial sex workers (CSW) and their clients, condom distribution in 10 busiest entertainment centers in

Kampala, and outreach voluntary HIV counseling and testing (VCT).

In FY08 the program will continue to provide training for health care providers and provision of PEP in all

the HIV testing, care and treatment sites that are supported by MJAP (14 HIV clinics, Mulago, Mbarara and

five regional referral hospitals). We will strengthen the prevention with positives and family planning

activities in all clinics, and will involve People living with HIV/AIDS (PHA) in prevention education and

counseling for patients. We will also strengthen the support for discordant couples identified through HIV

testing programs. All HIV testing facilities and care and treatment sites will provide condoms to support

discordant couples, in addition to the prevention counseling. Through collaboration with the Mulago STD

clinic, we will also provide STI diagnosis and treatment and HIV testing for some individuals referred from

the community. Within the community we will provide outreach voluntary HIV counseling and testing (VCT).

High-risk and CSW communities have organized networks with peer leaders (queen mothers). We will use

peer leaders to distribute coupons for facility based VCT for individuals who do not wish to test within the

community. These coupons will be numbered and tracked to evaluate the response rate of these referrals.

HIV infected individuals identified through community-based and facility-based HIV testing activities will be

referred to MJAP supported clinics and others facilities within Kampala. Education within the community will

address STI and HIV prevention, and will address the entire spectrum of prevention (AB and condom use)

as appropriate. We will identify and train peer leaders to mobilize the high-risk communities, provide

education and support for distribution of condoms. We will also work with bar owners and attendants to

distribute condoms through 10 established outlets for high-risk groups. Through these activities we will

reach over 3,500 individuals in high-risk communities. Overall, 40,000 individuals will be supported in FY

2008 (includes HIV positive patients in the clinics, discordant couples, and high-risk groups in selected

communities in Kampala). The other prevention program will have 31 condom distribution outlets (all 14 HIV

clinics, 10 community outlets for high-risk groups, Mulago and Mbarara, and five regional referral hospitals).

The ‘other prevention' budget will cover training, information, education, and communication materials,

health education and support for the PHA who will be involved in the prevention interventions. We will also

improve on the data management, reporting and M&E for ‘other prevention' programs. The capacity of the

STD laboratory will be reinforced through purchase of additional laboratory supplies. We will also procure

some additional drugs for treatment of STIs in order to supplement the MOH drugs, and support additional

Activity Narrative: staff to improve the clinical management at the unit. The ARV drugs for PEP and supplies for HIV testing

will be covered under the ART drugs and HIV counseling and testing budgets. Training in PEP for health

care providers and service provision at the clinic sites will be continued.

Funding for Sexual Prevention: Other Sexual Prevention (HVOP): $0

This activity refers to the CDC component ($166,000) of the three-country PEPFAR Gender Special

Initiative on Gender-Based Violence and covers the funds allocated by OGAC to PEPFAR Uganda. This

funding is not tied to any specific fiscal year and will be allocated to TBD existing partners.

This activity links to:The HQ-led component of the Initiative implemented by two USAID-funded Technical

Assistance partners, the Population Council and Health Policy Initiative; Any additional activities that may

build upon Special Initiative activities with FY08 funding.

The overall goal of the Special Initiative is to increase access for victims of sexual violence to

comprehensive treatment services, including HIV post-exposure prophylaxis (PEP) in three selected

countries: Rwanda, Uganda and South Africa. Lessons learned from these three countries will be used to

inform program design and scale-up in countries throughout Africa.

Specific Initiative objectives are to:

1) Implement and evaluate comprehensive sexual violence services delivery models building upon existing

services in the three selected PEPFAR focus countries. This includes to: Strengthen the capacity of local

partners and institutions to deliver quality health care services to victims of sexual violence, e.g., medical

management of sexual violence at the point of first contact with victims (including children), HIV PEP, and

psychological counseling; Establish and strengthen linkages between health, law enforcement, legal, and

community services (e.g., shelter, child care, economic opportunities, etc.) for delivery of a coordinated

response to sexual violence victims; and

Assess changes in the utilization and quality of services.

2) Measure the costs (and cost effectiveness) of implementing the service delivery models to inform model

transfer and scale-up.

3) Foster South-South exchange of programmatic experience, protocols, and tools across the three

countries and through linkages with a network of partners throughout Africa that are implementing similar

service delivery models.

Funding for initiative activities in Uganda will be used to:

•Implement the services strengthening activities described above in selected pilot locations where the

designated partners currently work -- in partnership with relevant government, local NGO, and other

community organizations;

•Participate in training and technical assistance activities that will be provided by the two Technical

Assistance partners for the Special Initiative and by other training partners funded through linked activities;

•Support collaboration across all Ugandan partners that are participating in the Initiative;

•Assist the Technical Assistance Partners in evaluating and measuring costs of the interventions through

input into the design of these evaluations and data collection;

•Participate in discussions and forums with partners from the other Initiative countries and other

organizations from throughout Africa to share tools, protocols and lessons.

Funding for Sexual Prevention: Other Sexual Prevention (HVOP): $0

This activity refers to the CDC component ($166,000) of the three-country PEPFAR Gender Special

Initiative on Gender-Based Violence and covers the funds allocated by OGAC to PEPFAR Uganda. This

funding is not tied to any specific fiscal year and will be allocated to TBD existing partners.

This activity links to:The HQ-led component of the Initiative implemented by two USAID-funded Technical

Assistance partners, the Population Council and Health Policy Initiative; Any additional activities that may

build upon Special Initiative activities with FY08 funding.

The overall goal of the Special Initiative is to increase access for victims of sexual violence to

comprehensive treatment services, including HIV post-exposure prophylaxis (PEP) in three selected

countries: Rwanda, Uganda and South Africa. Lessons learned from these three countries will be used to

inform program design and scale-up in countries throughout Africa.

Specific Initiative objectives are to:

1) Implement and evaluate comprehensive sexual violence services delivery models building upon existing

services in the three selected PEPFAR focus countries. This includes to: Strengthen the capacity of local

partners and institutions to deliver quality health care services to victims of sexual violence, e.g., medical

management of sexual violence at the point of first contact with victims (including children), HIV PEP, and

psychological counseling; Establish and strengthen linkages between health, law enforcement, legal, and

community services (e.g., shelter, child care, economic opportunities, etc.) for delivery of a coordinated

response to sexual violence victims; and

Assess changes in the utilization and quality of services.

2) Measure the costs (and cost effectiveness) of implementing the service delivery models to inform model

transfer and scale-up.

3) Foster South-South exchange of programmatic experience, protocols, and tools across the three

countries and through linkages with a network of partners throughout Africa that are implementing similar

service delivery models.

Funding for initiative activities in Uganda will be used to:

•Implement the services strengthening activities described above in selected pilot locations where the

designated partners currently work -- in partnership with relevant government, local NGO, and other

community organizations;

•Participate in training and technical assistance activities that will be provided by the two Technical

Assistance partners for the Special Initiative and by other training partners funded through linked activities;

•Support collaboration across all Ugandan partners that are participating in the Initiative;

•Assist the Technical Assistance Partners in evaluating and measuring costs of the interventions through

input into the design of these evaluations and data collection;

•Participate in discussions and forums with partners from the other Initiative countries and other

organizations from throughout Africa to share tools, protocols and lessons.

Funding for Care: Adult Care and Support (HBHC): $1,460,000

Makerere University Faculty of Medicine was awarded a cooperative agreement titled "Provision of routine

HIV testing, counseling, basic care and antiretroviral therapy at teaching hospitals in the Republic of

Uganda" in 2004. The program named Mulago-Mbarara Teaching Hospitals' Joint AIDS Program (MJAP)

implements HIV/AIDS services in Uganda's two major teaching hospitals (Mulago and Mbarara) and their

catchment areas in close collaboration with the national programs run by the Ministry of Health (MOH).

MJAP also collaborates with the National Tuberculosis and Leprosy Program (NTLP), and leverages

resources from the Global Fund. MJAP provides comprehensive HIV/AIDS services including: 1) hospital-

based routine HIV testing and counseling (RTC), 2) palliative HIV/AIDS basic care, 3) integrated TB-HIV

diagnosis with treatment of TB-HIV co-infected patients, 4) ART and HIV post- exposure prophylaxis, 5)

family based care (FBC) which includes services for orphans and vulnerable children (OVC), in addition to

home-based HIV testing and prevention activities (HBHCT), and 6) capacity building for HIV prevention and

care through training of health care providers, laboratory strengthening, and establishment of satellite HIV

clinics. Mulago and Mbarara hospitals are public referral institutions with a mandate of training, service-

provision and research. Annually 3,000 health care providers are trained and about one million patients

seen in the two hospitals (500,000 outpatients and 130,000 inpatients for Mulago, and 300,000 in and

outpatients for Mbarara). Approximately 60% of medical admissions in both hospitals are because of HIV

infection and related complications. Within Mulago, MJAP works closely with the Infectious Diseases

Institute (IDI). IDI is an independent institute within the Faculty of Medicine of Makerere University with a

mission to build capacity for delivering sustainable, high-quality HIV/AIDS care, treatment and prevention in

Africa through training and research. At IDI health care providers from all over sub-Saharan Africa receive

training on HIV care and ART; people living with HIV (PHA) receive free clinical care including ART at the

Adult Infectious Diseases Clinic (AIDC) - the clinic is integral with Mulago teaching hospital. The main HIV

clinics in Mbarara and Mulago teaching hospitals are the Mbarara ISS (HIV) clinic and AIDC, respectively;

MJAP supports HIV care and treatment in both clinics. In FY 2005 and FY 2006 MJAP opened eight

satellite clinics within the catchment areas of these two clinics due to the rapidly increasing demand for

HIV/AIDS care services; increasing the total number of treatment sites to 10. The eight satellite clinics

include Mulago hospital ISS clinic, Kawempe, Naguru, Kiswa and Kiruddu (under Kampala City Council -

KCC), Mbarara municipality clinic (under the Mbarara municipal council), Bwizibwera health center IV

(under MOH and Mbarara local government), and Mulago TB/HIV clinic, which provides care for TB-HIV co-

infected patients. The satellite clinic activities are implemented in collaboration with several partners

including KCC, Mbarara Municipal Council, IDI, Baylor-Paediatric Infectious Disease Clinic (PIDC),

Protection of Families against AIDS (PREFA), MOH, and other partners.

MJAP palliative basic care activities are currently implemented at 10 sites as listed above, with over 27,000

patients in active care; 9,000 at AIDC and 5,500 at Mbarara ISS. Mulago ISS, the largest of the new clinics

has registered over 5,000 patients while the smaller seven satellite clinics serve more than 8,000 patients.

The number of HIV patients in all the clinics continues to increase with the expansion of RTC in the

hospitals (over 18,000 HIV infected individuals were identified through RTC in FY 2006). By March 2008,

12 clinics will be operational and providing palliative basic care (two additional satellite clinics will be

established in collaboration with KCC and IDI). The palliative basic care activities include provision of a

package comprising cotrimoxazole for prophylaxis, insecticide treated mosquito nets, safe water provision

for diarrhea prevention, diagnosis and treatment of malaria and other opportunistic infections (OI). All

patients attending the HIV clinics receive daily cotrimoxazole for prophylaxis. Newly diagnosed HIV positive

patients from the RTC program also receive a month's supply of cotrimoxazole prophylaxis and are

provided with referrals for follow-up care in the HIV clinics. Patients eligible for ART are able to access

services at the same clinics. The AIDC and Mbarara ISS clinics provide care for adult patients while children

receive care from PIDC and Mbarara paediatric HIV clinics. However, in the satellite clinics MJAP

collaborates with other partners to provide comprehensive HIV care to entire families, including children in

collaboration with PIDC, KCC, MOH , NTLP and other partners. KCC provides clinic space and drugs for

management of OI. NTLP provides TB medications and support supervision. Other existing HIV programs

include VCT under AIDS Information Centre, PMTCT under PREFA, ART under MOH-Global Fund

Program and PEPFAR, and OVC support through Ministry of Gender, Labour and Social Development.

These programs are working together to ensure comprehensive care for families affected by HIV/AIDS

while avoiding duplication of services. Up to 27,000 individuals in the MJAP supported outlets are provided

with care including prophylaxis and treatment of opportunistic infections. More than 14,000 have received

safe water vessels and insecticide treated mosquito nets. The program also offers pre and in-service

training in palliative care to medical and other allied health workers.

In FY 2008 (between April 2008 and March 2009), two additional satellite care and treatment sites will be

established in collaboration with IDI bringing the total number to 14. The program will increase access to

basic HIV palliative care from 40,000 individuals to 70,000 (including 30,000 newly diagnosed patients who

will receive one month's supply of cotrimoxazole) prior to referral. MJAP will provide cotrimoxazole

prophylaxis and other OI care, malaria diagnosis and treatment, and Population Services International (PSI)

will provide safe water supplies and insecticide treated mosquito nets. We will supplement the basic care

items from PSI to ensure that at least 90% of the patients have access to mosquito nets and safe water.

The basic care and ART programs are integrated; all patients on ART receive basic care, and patients

receiving basic care are evaluated for ART eligibility. The funding will support the 14 clinics in terms of basic

care supplies, and other OI treatment and prophylaxis. Children within the clinics will receive some

nutritional supplementation and will also be linked to other partners for additional OVC services. Through

the home-based HIV care program which targets families of HIV infected patients in the clinics, the non-HIV

infected children within these households will also be linked to OVC services. The home-based care

program will continue to provide HIV testing for all family members, and support disclosure to partners

through counselor-assistance when requested; this will ensure that all family members including men,

women and children are served. In line with Uganda's HIV/AIDS National Strategic Plan 2007/2008-

2011/12, MJAP will extend RTC services to regional referral hospitals (eight regional referral hospitals will

have functional RTC programs in FY 2008). All newly diagnosed HIV positive patients in these hospitals will

receive a month's supply of cotrimoxazole before referral for follow-up palliative care and treatment. To

ensure sustainability, MJAP will support the improvement of existing structures and systems within the

facilities. The program will hire additional staff to support care and prevention efforts, provide training for

new and existing staff in the clinics 300 health care providers will be trained in the coming year), support

logistics management and supplies, quality assurance and support supervision, and enhance the existing

referral systems between the main HIV clinics and the satellite clinics, and linkage to care for newly

diagnosed HIV patients. The program will also support the improvement of data management/ M&E and

reporting to all stakeholders within the districts and MOH. The program has recently developed a strategy

Activity Narrative: for involvement of PHA in aspects of patient care, and training of the PHA has commenced. The strategy

also addresses issues of PHA supervision and motivation.

Funding for Care: TB/HIV (HVTB): $500,000

Makerere University Faculty of Medicine was awarded a cooperative agreement titled "Provision of routine

HIV testing, counseling, basic care and antiretroviral therapy at teaching hospitals in the Republic of

Uganda" in 2004. The program named Mulago-Mbarara Teaching Hospitals' Joint AIDS Program (MJAP)

implements HIV/AIDS services in Uganda's two major teaching hospitals (Mulago and Mbarara) and their

catchment areas in close collaboration with the national programs run by the Ministry of Health (MOH).

MJAP also collaborates with the National tuberculosis and Leprosy Program (NTLP), and leverages

resources from the Global fund. MJAP provides comprehensive HIV/AIDS services including: 1) hospital-

based routine HIV testing and counseling (RTC), 2) palliative HIV/AIDS basic care, 3) integrated TB-HIV

diagnosis with treatment of TB-HIV co-infected patients, 4) ART and HIV post- exposure prophylaxis, 5)

family based care (FBC) which includes services for orphans and vulnerable children (OVC), in addition to

home-based HIV testing and prevention activities (HBHCT), and 6) capacity building for HIV prevention and

care through training of health care providers, laboratory strengthening, and establishment of satellite HIV

clinics. Mulago and Mbarara hospitals are public referral institutions with a mandate of training, service-

provision and research. Annually 3,000 health care providers are trained and about one million patients

seen in the two hospitals (500,000 outpatients and 130,000 inpatients for Mulago, and 300,000 in and

outpatients for Mbarara). Approximately 60% of medical admissions in both hospitals are because of HIV

infection and related complications. Within Mulago, MJAP works closely with the Infectious Diseases

Institute (IDI). IDI is an independent institute within the Faculty of Medicine of Makerere University with a

mission to build capacity for delivering sustainable, high-quality HIV/AIDS care, treatment and prevention in

Africa through training and research. At IDI health care providers from all over sub-Saharan Africa receive

training on HIV care and antiretroviral therapy (ART); people living with HIV receive free clinical care

including ART at the Adult Infectious Diseases Clinic (AIDC) - the clinic is integral with Mulago teaching

hospital. The main HIV clinics in Mbarara and Mulago teaching hospitals are the Mbarara ISS (HIV) clinic

and AIDC, respectively; MJAP supports HIV care and treatment in both clinics. In FY 2005 and FY 2006

MJAP opened eight satellite clinics within the catchment areas of these two clinics due to the rapidly

increasing demand for HIV/AIDS care services; increasing the total number of treatment sites to 10. The

eight satellite clinics include Mulago hospital ISS clinic, Kawempe, Naguru, Kiswa and Kiruddu (under

Kampala City Council - KCC), Mbarara municipality clinic (under the Mbarara municipal council),

Bwizibwera health center IV (under MOH and Mbarara local government), and Mulago TB/HIV clinic, which

provides care for TB-HIV co-infected patients. The satellite clinic activities are implemented in collaboration

with several partners including KCC, Mbarara Municipal Council, IDI, Baylor-Paediatric Infectious Disease

Clinic (PIDC), Protection of Families against AIDS (PREFA), MOH, and other partners.

MJAP supports a TB screening program, which is aimed at augmenting TB diagnosis in Mulago and

Mbarara hospital wards and the specialized HIV/AIDS clinics. TB and HIV service integration happens at

several levels 1) integration of TB screening and RTC on the wards/clinics, where patients are offered both

HIV testing and screening for TB, 2) RTC in the TB wards and clinics, 3) enhanced TB screening in all the

supported HIV clinics, and 4) provision of both TB and HIV care and treatment for patients who are co-

infected with TB and HIV. Implementation of the TB screening and treatment services is done in

collaboration with MOH-NTLP. The MOH-NTLP supplies free TB medications, some laboratory equipment

and reagents; the HIV clinics dispense TB medications supplied by MOH-NTLP, monitor patients, and

report regularly to MOH-NTLP. Since February 2005, over 20,000 individuals have been screened for TB

and more than 2,000 sputum positive patients identified and linked to care. Additionally, more than 1,500

patients have received TB and HIV treatment in the HIV care centers. The program established a special

TB-HIV clinic in Mulago that provides care for TB-HIV co-infected patients. In this clinic, TB/HIV patients

receive TB treatment, HIV palliative and basic care, assessment for ART eligibility, and initiation of ART if

eligible. After completion of TB treatment, these patients are referred for follow-up HIV care in the other

established clinics. The TB-HIV clinic has provided care for more than 700 adult TB-HIV patients since

September 2005, 52% of who also received ART (children receive care from PIDC and the Mbarara

pediatric HIV clinic). The program is also currently setting up an integrated TB-HIV clinic in Mbarara

hospital. TB treatment has been integrated into all the other care and treatment sites, with a dedicated day

for treatment of co-infected patients in each site. Integrated TB-HIV diagnosis has been extended to three

regional referral hospitals in FY 2007.

In FY08 (April 2008 to march 2009), two new satellite care and treatment sites will be opened in

collaboration with IDI. The integrated RTC-TB screening program will also be expanded to 2 additional

MOH regional referral hospitals. It is expected that integrated TB/HIV activities will be replicated at five

regional referral hospitals in collaboration with MOH and NTLP. This funding will support TB screening in 21

sites (Mulago and Mbarara hospital wards, five regional referral hospitals, and all the 14 MJAP supported

HIV clinics); 14 sites will provide integrated care and treatment while seven will provide integrated diagnosis

with referral to existing care and treatment facilities. The aim is to screen 25,000 patients for TB and provide

TB-HIV care to 2,000 TB-HIV co-infected patients in the coming year. To ensure sustainability, MJAP will

continue to support the improvement of existing structures and systems within the facilities. The program

will hire additional staff to support the TB-HIV integration efforts, provide training for new and existing staff

in the clinics (400 health care providers will be trained in the coming year), support logistics management

and supplies, quality assurance and support supervision, and enhance the existing referral systems

between the diagnosis and the care and treatment sites. The program will also support the improvement of

data management/M&E and reporting to all stakeholders within the districts, zonal supervision offices and

MOH-NTLP. Although implementation will happen in the regional and national referral hospitals, health

providers in the lower level health centers (including CB-DOTS providers) will also be trained, to enhance

TB-HIV care and CB-DOTS. The laboratory personnel at the regional referral hospitals will be trained and

supported to provide support supervision for the lower level laboratories (an area within their mandate but

currently not fully implemented). The HIV testing, care and treatment supplies will be covered under the

care, treatment and CT budgets. The program will target both adults and children in all the clinics and

hospitals.

Funding for Care: TB/HIV (HVTB): $1,400,000

Makerere University Faculty of Medicine is expanding TB/HIV integration.The program,Mulago-Mbarara

Teaching Hospitals' Joint AIDS Program (MJAP), implements HIV/AIDS services in Uganda's 2 major

teaching hospitals at Mulago & Mbarara & their catchment areas in close collaboration with MOH national

programs. MJAP also collaborates with NTLP & leverages resources from GFATM. It provides

comprehensive HIV/AIDS services including: hospital-based RTC; palliative HIV/AIDS care; integrated TB-

HIV diagnosis with treatment of TB-HIV co-infected patients; ART & HIV PEP; family based care (FBC)

including OVC services, home-based HIV testing & prevention activities (HBHCT); capacity building for HIV

prevention & care through training HCWs, lab strengthening, & establishment of satellite HIV clinics. The

hospitals are public referral institutions with a mandate of training, service-provision & research.

Approximately 60% of medical admissions are due to HIV infection & related complications. MJAP works

closely with IDI, an independent institute within the Faculty of Medicine & has a mission to build capacity for

delivering sustainable, high-quality HIV/AIDS care, treatment & prevention in Africa through training &

research. PHAs receive free clinical care including ART at the Adult Infectious Diseases Clinic (AIDC);

MJAP supports HIV care & treatment at Mbarara ISS clinic & AIDC. In FY05/FY06 MJAP opened 8 satellite

clinics: Mulago Hospital ISS clinic, Kawempe,Naguru,Kiswa,Kiruddu (under Kampala City Council - KCC),

Mbarara Municipality Clinic (under Mbarara Municipal Council), Bwizibwera HCIV (under MOH/Mbarara

local government), & Mulago TB/HIV clinic, which provides care for TB-HIV co-infected patients. Satellite

clinic activities are conducted with other partners. MJAP integrated TB services into its HIV testing & care

programs in 2005 & expanded these services to regional referral hospitals starting with Jinja. TB/HIV

integrated services include diagnosis of TB & HIV infections among in- & out-patients in general wards &

clinics through integrated routine HCT & TB diagnosis, enhanced TB screening for HIV positive patients in

care including those on ART, HIV testing for hospitalized TB patients on anti TB treatment, & linkage of

infected patients to existing care & treatment services. TB screening is conducted at several levels

beginning with clinical evaluation. The main diagnostic tool is sputum smear microscopy, CXR for those

who have no cough & biopsies for the extra pulmonary TB. MOH, NTLP & MJAP reviewed existing

materials on HIV & TB care & developed training materials for HCWs in delivery of integrated TB-HIV

diagnosis, care & treatment. MOH & MJAP assessed the existing TB-HIV services at Jinja hospital to

identify strengths & gaps. Gaps were identified in: number of clinical personnel in medical units, lab

equipment & supplies for TB/HIV testing & treatment monitoring, logistics management system, data

management system, the hospital community health department which is responsible for monitoring TB

treatment & care, referral & follow-up, & skills in TB-HIV collaborative activities. Gaps were addressed

through: development of TB-HIV training materials & training of staff in various aspects of TB-HIV diagnosis,

procurement of lab equipments/supplies, training in logistics management, development of data tools,

databases & procurement of computers to enhance data management, M&E/reporting. Since December

2006, the program has provided HIV counseling and testing to over 3952 patients, 768 of whom tested

positive. 741 patients with TB symptoms were screened including sputum smears, 125 were found to have

smear-positive TB. 178 patients were co-infected and are receiving treatment in the Jinja hospital clinic.

Scale-up of service delivery has just started because the focus was on training & improving systems &

infrastructure. In FY08 MJAP will consolidate & strengthen existing TB-HIV services in Jinja Hospital to

include care & treatment for patients with both TB & HIV. MJAP will also expand integrated activities to 2

additional hospitals (Hoima & a third hospital to be identified in consultation with MOH). The 2 hospitals will

be supported to develop TB infection control plans & to implement procedures e.g. establishment of

infection control committees, early recognition of suspects, education on cough hygiene, provision of

protectives such as masks, tissues & contact tracing for all patients with TB disease seen in the hospital. To

ensure sustainability, MJAP will continue to support improvement of existing structures & systems within the

hospitals. Additional staff will be hired to support data management, M&E, reporting, integrated TB-HIV

services, training staff (200 HCWs will be trained in coming year), support logistics management & supplies,

quality assurance & support supervision, & enhance the existing referral systems between the regional

referral hospitals & lower level health facilities, & linkage to care for newly diagnosed TB-HIV patients.

Reporting to MOH &all stakeholders within the districts will improve. MJAP has recently developed a

strategy for involvement of PHAs in patient care, & training has commenced. The strategy addresses issues

of PHA supervision & motivation. MJAP will support regional referral hospitals to enhance support

supervision for lower level units. IPT activities will be piloted in Mulago HIV/AIDS clinic & scaled up sites

after an assessment of several parameters including patient follow-up, monitoring, adherence rates &

support mechanisms, & side effects to INH. Patients with latent infection of mycobacterium TB & HIV-

infected patients will receive IPT according to WHO & MOH/NTLP guidelines. MJAP will develop/update

current guidelines for provision of IPT & IEC materials for patient education; the data management system

will be finalized, HCWs will be trained in the provision of IPT. NTRL, which is a sub partner, supports NTLP

to achieve its aim of TB case finding & management by supporting sputum smear microscopy services

country wide. NTRL's provides training, supervision & QA with an emphasis on EQA as a priority to the

district labs & NGOs supporting CB-DOTS programs & providing reference support to the districts in the

diagnosis & monitoring of extremely difficult cases, as well as support for national TB drug resistance

surveillance. NTRL aims at strengthening & intensifying TB screening in HIV/AIDS infected patients &

encourages HIV screening to TB patients. Realization of these goals depends on nationwide coverage of an

EQA system at HIV prevention, care, & treatment sites as well as training & re-training in basic TB

diagnostic procedures & establishing a system that encourages & provides all TB patients with access to

HIV screening. NTRL expects TB/HIV collaborative activities will lead to increased detection & treatment of

TB among PLHAs. In addition, an increased number of TB patients will have their HIV status established.

The burden of TB/HIV co-infection will be reduced by providing quality AFB smear diagnostic services.

These services will be achieved through implementation of an EQA scheme & targeted supportive

supervision as well as refresher trainings which will be conducted at NTRL's newly equipped training lab.

The improvement of human resource development in qualitative & quantitative aspects will improve

accessibility to TB diagnostics services for patients with HIV/AIDS. FY07 achievements include the

introduction of EQA in Western & Northern Zones & strengthening of EQA in Kampala, South Western,

South Eastern, Central, Eastern & North Western Zones through re-visiting of areas with inadequate

performance e.g. slides not collected or technical problems, provision of feedback reports to DTLS for

further encouragement to continue collecting slides & addressing administrative problems concerning

forwarding of slides & transmitting feedback reports; protocol to establish a system of sample transport as

well as piloting drug surveillance has been completed & purchasing of sample carrier boxes is in process.

Rehabilitation of the training lab, offices & wash up was completed; plans for rehabilitation of the TB culture

lab have been approved; 2 laptop computers, 248 EQA slide boxes, 1 refrigerator, 1 Water distiller, 40

chairs & stools for the training room & 1 media hood were purchased. A MGIT culture system will be

purchased. 4363 TB tests were performed, 2095 TB cultures were done, 2018 fluorescent slides were read

& 250 susceptibility tests were made; 320 slides for EQA activities were read & 205 feedback reports were

Activity Narrative: written & sent back to districts for targeted support supervision;160 people were trained in TB/HIV activities

& 200 TB/HIV diagnostic units districts were supervised. Due to improvements made, NTRL has been

nominated to become a supra national reference lab in the region. FY08 will focus on further strengthening

the EQA System by increased problem-oriented supervision as well as training of lab staff & consolidation in

the poorly performing areas. District & regional labs will be strengthened to sustain the EQA System. 100

lab staff will be trained & DFLPs will carry out support & problem-oriented supervision. A lab coordinator will

be hired to oversee the daily activities, prepare, submit & follow up EQA reports to peripheral labs, compile

budgets & prepare quarterly reports. A data manager will also be hired. NTRL will also focus on better

patient care for HIV/AIDS patients through purchase & use of more sensitive fluorescent (LED) microscopes

for busy HIV/AIDS care centers, identifying possible MDR through a specimen referral system & expansion

of TB culture facilities to 2 other labs. Second line drug susceptibility testing as well as rapid MDR-TB

screening tests will be introduced to support the DOTS-plus programs. Support training for roll-out of

national TB speciman referral system with Uganda Central Public Health Laboratory.

Funding for Care: Orphans and Vulnerable Children (HKID): $200,000

Makerere University Faculty of Medicine was awarded a cooperative agreement titled "Provision of routine

HIV testing, counseling, basic care and antiretroviral therapy at teaching hospitals in the Republic of

Uganda" in 2004. The program named Mulago-Mbarara Teaching Hospitals' Joint AIDS Program (MJAP)

implements HIV/AIDS services in Uganda's two major teaching hospitals (Mulago and Mbarara) and their

catchment areas in close collaboration with the national programs run by the Ministry of Health (MOH).

MJAP also collaborates with the National tuberculosis and Leprosy Program (NTLP), and leverages

resources from the Global fund. MJAP provides comprehensive HIV/AIDS services including: 1) hospital-

based routine HIV testing and counseling (RTC), 2) palliative HIV/AIDS basic care, 3) integrated TB-HIV

diagnosis with treatment of TB-HIV co-infected patients, 4) ART and HIV post- exposure prophylaxis, 5)

family based care (FBC) which includes services for orphans and vulnerable children (OVC), in addition to

home-based HIV testing and prevention activities (HBHCT), and 6) capacity building for HIV prevention and

care through training of health care providers, laboratory strengthening, and establishment of satellite HIV

clinics. Mulago and Mbarara hospitals are public referral institutions with a mandate of training, service-

provision and research. Annually 3,000 health care providers are trained and about one million patients

seen in the two hospitals (500,000 outpatients and 130,000 inpatients for Mulago, and 300,000 in and

outpatients for Mbarara). Approximately 60% of medical admissions in both hospitals are because of HIV

infection and related complications. Within Mulago, MJAP works closely with the Infectious Diseases

Institute (IDI). IDI is an independent institute within the Faculty of Medicine of Makerere University with a

mission to build capacity for delivering sustainable, high-quality HIV/AIDS care, treatment and prevention in

Africa through training and research. At IDI health care providers from all over sub-Saharan Africa receive

training on HIV care and antiretroviral therapy (ART); people living with HIV receive free clinical care

including ART at the Adult Infectious Diseases Clinic (AIDC) - the clinic is integral with Mulago teaching

hospital. The main HIV clinics in Mbarara and Mulago teaching hospitals are the Mbarara ISS (HIV) clinic

and AIDC, respectively; MJAP supports HIV care and treatment in both clinics. In FY 2005 and FY 2006

MJAP opened eight satellite clinics within the catchment areas of these two clinics due to the rapidly

increasing demand for HIV/AIDS care services; increasing the total number of treatment sites to 10. The

eight satellite clinics include Mulago hospital ISS clinic, Kawempe, Naguru, Kiswa and Kiruddu (under

Kampala City Council - KCC), Mbarara municipality clinic (under the Mbarara municipal council),

Bwizibwera health center IV (under MOH and Mbarara local government), and Mulago TB/HIV clinic, which

provides care for TB-HIV co-infected patients. The satellite clinic activities are implemented in collaboration

with several partners including KCC, Mbarara Municipal Council, IDI, Baylor-Paediatric Infectious Disease

Clinic (PIDC), Protection of Families against AIDS (PREFA), MOH, and other partners.

OVC activities have been integrated into all MJAP programs. These activities include HIV testing, linkage to

HIV/AIDS care for the positives, psychosocial support, nutrition education as well as referral for other OVC

services that MJAP does not offer. The OVC services are provided for the following categories of children:

1) Children receiving HIV care and treatment in the 10 clinics, 2) Children of HIV infected patients within the

clinics (seen at home through the home based care program), 3) Children receiving RTC in the hospital

wards and clinics, 4) Exposed children (children born to HIV infected women) followed up within the

hospitals. The MJAP RTC program provides HIV testing to children in six pediatric wards (five in Mulago

and one in Mbarara hospital). The current program also provides HIV Counseling and Testing to family

members of patients in the hospital, including children of HIV infected patients. The program provides

HBHCT for family members of index HIV patients in Bwizibwera, Mbarara Municipality, Kawempe and

Naguru health centers, and the Mulago ISS clinic. The program has hired social workers who work closely

with health care providers to identify families of OVC from among the patients receiving care within the

clinics or those receiving HIV testing. Through these activities, over 3,000 children have received HIV

testing (15% of who were HIV-infected) and more than 1,500 households of index HIV positive patients

have been visited. In the satellite clinics,, MJAP provides family-based HIV care and treatment and OVC

and their caretakers receive services through this intervention.

In FY08 (April 2008 to March 2009), the program will continue to provide HIV testing, care and treatment to

OVC and their caretakers. We will improve the linkage with PMTCT facilities within Jinja and Mbarara

hospitals, and tracking of exposed children, with early diagnosis and linkage to care (PREFA and PIDC do

the follow-up for the Kampala-based sites). Children will receive some food, and basic care items. Exposed

children who will be followed up will also receive some food supplements; a snack for the children as they

wait to be seen and a package of foods for the children when they leave the clinic (once a month). The

home-based teams will also leave a small package of food for the children within the home, in addition to

the basic care items (mosquito nets, safe water vessels, cotrimoxazole for those who are HIV infected, and

de-worming of all children within the homes). HIV infected children will receive care and treatment in the

clinics. Referral linkages with other OVC service providers will be strengthened for other OVC services

including ongoing psychosocial support and counseling, vocational and life skills training, legal support,

educational and nutritional support, and income generating activities; we are in the process of signing

memorandum of understanding with three OVC service providers. Through these programs we hope to

reach 4,500 OVC and their caretakers. The OVC budget will cover personnel who will provide OVC

services, counseling, development of referral networks and linkage to other OVC services. The program will

also train providers in the clinics and C&T services to enable them initiate and provide referral for OVC

services; 150 OVC care givers will be trained in FY08. Other requirements for OVC care and treatment will

be covered under palliative care; basic care and support, ART services, ART drugs, ART laboratory

services, and counseling and testing budgets.

Funding for Testing: HIV Testing and Counseling (HVCT): $1,400,000

Makerere University Faculty of Medicine was awarded a cooperative agreement titled "Provision of routine

HIV testing, counseling, basic care and antiretroviral therapy at teaching hospitals in the Republic of

Uganda" in 2004. The program named Mulago-Mbarara Teaching Hospitals' Joint AIDS Program (MJAP)

implements HIV/AIDS services in Uganda's two major teaching hospitals (Mulago and Mbarara) and their

catchment areas in close collaboration with the national programs run by the Ministry of Health (MOH).

MJAP also collaborates with the National tuberculosis and Leprosy Program (NTLP), and leverages

resources from the Global fund. MJAP provides comprehensive HIV/AIDS services including: 1) hospital-

based routine HIV testing and counseling (RTC), 2) palliative HIV/AIDS basic care, 3) integrated TB-HIV

diagnosis with treatment of TB-HIV co-infected patients, 4) ART and HIV post- exposure prophylaxis, 5)

family based care (FBC) which includes services for orphans and vulnerable children (OVC), in addition to

home-based HIV testing and prevention activities (HBHCT), and 6) capacity building for HIV prevention and

care through training of health care providers, laboratory strengthening, and establishment of satellite HIV

clinics. Mulago and Mbarara hospitals are public referral institutions with a mandate of training, service-

provision and research. Annually 3,000 health care providers are trained and about one million patients

seen in the two hospitals (500,000 outpatients and 130,000 inpatients for Mulago, and 300,000 in and

outpatients for Mbarara). Approximately 60% of medical admissions in both hospitals are because of HIV

infection and related complications. Within Mulago, MJAP works closely with the Infectious Diseases

Institute (IDI). IDI is an independent institute within the Faculty of Medicine of Makerere University with a

mission to build capacity for delivering sustainable, high-quality HIV/AIDS care, treatment and prevention in

Africa through training and research. At IDI health care providers from all over sub-Saharan Africa receive

training on HIV care and ART; people living with HIV (PHA) receive free clinical care including ART at the

Adult Infectious Diseases Clinic (AIDC) - the clinic is integral with Mulago teaching hospital. The main HIV

clinics in Mbarara and Mulago teaching hospitals are the Mbarara ISS (HIV) clinic and AIDC, respectively;

MJAP supports HIV care and treatment in both clinics. In FY 2005 and FY 2006 MJAP opened eight

satellite clinics within the catchment areas of these two clinics due to the rapidly increasing demand for

HIV/AIDS care services; increasing the total number of treatment sites to 10. The eight satellite clinics

include Mulago hospital ISS clinic, Kawempe, Naguru, Kiswa and Kiruddu (under Kampala City Council -

KCC), Mbarara municipality clinic (under the Mbarara municipal council), Bwizibwera health center IV

(under MOH and Mbarara local government), and Mulago TB/HIV clinic, which provides care for TB-HIV co-

infected patients. The satellite clinic activities are implemented in collaboration with several partners

including KCC, Mbarara Municipal Council, IDI, Baylor-Paediatric Infectious Disease Clinic (PIDC),

Protection of Families against AIDS (PREFA), MOH, and other partners.

MJAP started implementing RTC in November 2004, in Mulago and Mbarara teaching hospitals. In RTC,

HIV testing is routinely offered to all patients seeking care in the wards/clinics where the program is

operational but those who decide not to test receive other clinical services without discrimination. HIV care,

including ART eligibility assessment, cotrimoxazole prophylaxis and TB screening, for individuals who are

HIV infected is initiated on diagnosis. The HIV negative patients are also screened for TB and both HIV

negative and positive patients receive prevention counseling. The program has trained over 1,200 health

care providers in Mulago and Mbarara hospitals in the provision of RTC. Since November 2004, the RTC

program has expanded from six to 42 hospital wards and clinics (23 in Mulago and 19 in Mbarara).

Cumulatively, more than 170,000 in- and outpatients have received HIV testing and over 35,000 HIV

infected individuals identified and linked to care and treatment. The current unit coverage represents 95% in

Mbarara. Although the unit coverage in Mulago is 50%, over 95% of the high prevalence units provide RTC.

In line with Uganda's HIV/AIDS National Strategic Plan 2007/2008-2011/12, MJAP has expanded RTC to

three regional referral hospitals; implementation in Soroti has already started. The RTC program is

implemented in line with the three C's - confidentiality, informed consent (opt out) and

counseling/information, as recommended by WHO, and the MOH HIV testing policy. HIV positive patients

are also referred for follow-up care in the HIV clinics where they receive basic HIV care, psychosocial

support and ART. For patients found to be HIV negative, HIV prevention messages are emphasized to

reduce risk of infection. Training in RCT for health providers from other units is ongoing at the request of

MOH. The program also implements other HIV testing strategies. MJAP offers VCT to family members of

patients who are available in the hospital and has found a high HIV prevalence (24%). In order to extend the

reach of HIV testing to family members, MJAP provides home-based HIV counseling and testing (HBHCT)

for index ART patients attending Bwizibwera and Kawempe health centers. In HBHCT, HIV counseling and

testing are offered within the homes of consenting index clients. This approach identifies other HIV infected

individuals in their households, facilitates disclosure of HIV status to sexual

partners and identifies many discordant couples. Additionally, testing of family members encourages early

entry into care and support for the HIV infected individuals.

In FY 2008 (between April 2008 and March 2009), MJAP will extend RTC services to two additional regional

referral hospitals, increasing the number to five. Patients from another three regional referral hospitals will

also receive HIV testing through the MJAP integrated TB-HIV services. We will achieve 100% coverage of

high-prevalence wards and clinics in Mulago and Mbarara hospitals. The regional hospitals will be selected

in collaboration with the MOH. The target is to provide HIV testing to a minimum of 170,000 individuals by

March 2009. In the RTC units, all patients with undocumented HIV status will be routinely offered HIV

testing but this will not preclude the right to opt-out of testing. The program will target all categories of

patients and family members; including adults, infants, children, health care workers, and MJAP program

staff. Through the HBHCT program, MJAP will provide HIV C&T to 2,000 households (10,000 family

members) of index patients in care. Newly diagnosed HIV positive patients will receive a month's supply of

cotrimoxazole before referral for follow-up palliative care and treatment. The program will integrate TB

screening for all newly diagnosed HIV-infected patients. MJAP will strengthen prevention with positives

counseling and support including HIV testing for spouses of patients in the HIV clinics and RTC wards.

Discordant couples will be referred to the ‘Discordant couples' clubs which are currently being piloted at two

sites. To ensure sustainability, MJAP will support the improvement of existing structures and systems within

the facilities. The program will support the engagement of PHA to supplement personnel for HIV counseling

and testing, provide training for new and existing staff in the facilities (800 health care providers will be

trained in the coming year), support logistics management and supplies, quality assurance and support

supervision, and enhance the existing referral systems to improve linkage to care for newly diagnosed HIV

patients. The program will also support the improvement of data management/ M&E and reporting to all

stakeholders within the districts and MOH.

Funding for Treatment: ARV Drugs (HTXD): $4,242,541

Makerere University Faculty of Medicine was awarded a cooperative agreement titled "Provision of routine

HIV testing, counseling, basic care and antiretroviral therapy at teaching hospitals in the Republic of

Uganda" in 2004. The program named Mulago-Mbarara Teaching Hospitals' Joint AIDS Program (MJAP)

implements HIV/AIDS services in Uganda's two major teaching hospitals (Mulago and Mbarara) and their

catchment areas in close collaboration with the national programs run by the Ministry of Health (MOH).

MJAP also collaborates with the National tuberculosis and Leprosy Program (NTLP), and leverages

resources from the Global fund. MJAP provides comprehensive HIV/AIDS services including: 1) hospital-

based routine HIV testing and counseling (RTC), 2) palliative HIV/AIDS basic care, 3) integrated TB-HIV

diagnosis with treatment of TB-HIV co-infected patients, 4) ART and HIV post- exposure prophylaxis, 5)

family based care (FBC) which includes services for orphans and vulnerable children (OVC), in addition to

home-based HIV testing and prevention activities (HBHCT), and 6) capacity building for HIV prevention and

care through training of health care providers, laboratory strengthening, and establishment of satellite HIV

clinics. Mulago and Mbarara hospitals are public referral institutions with a mandate of training, service-

provision and research. Annually 3,000 health care providers are trained and about one million patients

seen in the two hospitals (500,000 outpatients and 130,000 inpatients for Mulago, and 300,000 in and

outpatients for Mbarara). Approximately 60% of medical admissions in both hospitals are because of HIV

infection and related complications. Within Mulago, MJAP works closely with the Infectious Diseases

Institute (IDI). IDI is an independent institute within the Faculty of Medicine of Makerere University with a

mission to build capacity for delivering sustainable, high-quality HIV/AIDS care, treatment and prevention in

Africa through training and research. At IDI health care providers from all over sub-Saharan Africa receive

training on HIV care and antiretroviral therapy (ART); people living with HIV receive free clinical care

including ART at the Adult Infectious Diseases Clinic (AIDC) - the clinic is integral with Mulago teaching

hospital. The main HIV clinics in Mbarara and Mulago teaching hospitals are the Mbarara ISS (HIV) clinic

and AIDC, respectively; MJAP supports HIV care and treatment in both clinics. In FY 2005 and FY 2006

MJAP opened eight satellite clinics within the catchment areas of these two clinics due to the rapidly

increasing demand for HIV/AIDS care services; increasing the total number of treatment sites to 10. The

eight satellite clinics include Mulago hospital ISS clinic, Kawempe, Naguru, Kiswa and Kiruddu (under

Kampala City Council - KCC), Mbarara municipality clinic (under the Mbarara municipal council),

Bwizibwera health center IV (under MOH and Mbarara local government), and Mulago TB/HIV clinic, which

provides care for TB-HIV co-infected patients. The satellite clinic activities are implemented in collaboration

with several partners including KCC, Mbarara Municipal Council, IDI, Baylor-Paediatric Infectious Disease

Clinic (PIDC), Protection of Families against AIDS (PREFA), MOH, and other partners.

Currently, MJAP procures ARV drugs through Medical Access Uganda Limited and distributes them to 10

service outlets as listed above. The 10 service outlets serve over 27,000 patients in care, 4,215 of who have

their ARV drugs procured through MJAP funding. The current (June 2007) distribution of these patients are

900 at AIDC, 810 in Mbarara ISS clinic, 885 in Mulago ISS clinic, 352 in Mbarara municipality clinic, 350 in

Kawempe KCC, 246 in Bwizibwera HCIV, 72 at Mulago TB/HIV clinic, 200 in Naguru, and >400 at Kiruddu

and Kiswa combined. The target is to procure ARVs for up to 7,000 patients by March 2008. The program is

currently switching patients from branded ARVs to the available cheaper generic FDA approved ARVs to

further reduce the treatment costs. Demand for ART in the clinics continues to increase with the expansion

of RTC in the hospitals. The Mbarara ISS and Mulago AIDC will be at maximum capacity as a result by

March 2008 if the current trends of enrolment remain constant. Two additional satellite clinics will be

operational in Kampala by March 2008 (in collaboration with IDI and KCC), increasing the number of service

outlets to 12. Majority of HIV positive patients identified through the RTC program (over 70%) need ARVs

(WHO Stages 3 and 4). Currently, we estimate that only about 60% of clinically eligible patients are

receiving ART at the clinic sites. MJAP has trained over 500 health care providers in the provision of

antiretroviral therapy and strengthened systems for ART delivery including staffing, laboratory support,

logistics and data management. The ARVs forecasting is done for the entire year with quarterly revisions,

but purchase of drugs including three months buffer stock for each patient are done on a quarterly basis.

Drugs are delivered to the program store by Medical Access, checked and received by a pharmacist of the

program and storekeeper before storage. An entry is made into the goods received note (GRN) and stock

cards for all drug items received. Stocktaking and reporting is done monthly at the service delivery points

and quarterly at all stores. As a result of the capacity building of lower level clinics within the catchment's

areas of Mulago and Mbarara for HIV care by MJAP, an additional >6,500 patients are able to access ARV

drugs from MOH/GFATM at the MJAP supported sites. In the past year, due to ARV drug procurement

interruptions for Global Fund, MJAP supported the procurement of two to three months' buffer stock for up

to 3,000 of these patients.

In FY08 (April 2008 to March 2009), two new satellite care and treatment sites will be opened in

collaboration with IDI, bringing the total to 14 sites. With the increased access to FDA approved generic

ARVs registered in the country, there is an anticipated increase in number of ART eligible patients who will

be able receive treatment; the program will procure and distribute ARVs for at least 10,000 patients by

March 2009. Allocation of the slots across the 14 sites in FY08 will be done according to demand (number

of eligible patients) and capacity of the facilities. Special attention shall be given to pregnant women

attending the HIV clinics or referred from PMTCT sites. MJAP will hire and train new and existing staff to

enhance care in the clinics - 300 health care providers will receive training in ART delivery. Training shall

be for both program clinics and other national needs. Health care providers in three regional referral

hospitals will also receive training in logistics management for ART delivery. Training will ensure quality of

services and continued access to GFATM ARVs at the sites. Within Mulago and Mbarara hospitals, the

program will target mainly adult patients receiving care from all the clinics (children receive ART from the

PIDC, and the Mbarara pediatric HIV clinic); in the satellite clinics MJAP will support some children. The

funding for ART drugs will go towards the purchase of ARVs (including three months buffer for MOH/Global

fund patients), logistics and ARV drug distribution and tracking. MJAP ARV procurement in FY08 will

continue to happen through Medical Access Uganda Limited. The ARVs forecasting, procurement (including

a three month buffer stock for all patients) will continue on a quarterly basis. Drugs will be delivered to the

program store by Medical Access, checked and received by the program pharmacist and storekeeper

before storage. An entry is made into the goods received note (GRN) and stock cards for all drug items

received. Monthly stocktaking and reporting will continue at the service delivery points and quarterly at all

stores. MJAP will continue to support training of pharmacy technicians, stores and logistics managers in the

partners' sites to improve on the overall management of logistics for drugs and other supplies; this activity

will continue in FY 2008. It is anticipated that some ARV drugs especially second line regimens will be

donated by the Clinton Foundation.

In FY08, MJAP anticipates that Ministry of Health and the Clinton Foundation/UNITAID will provide pediatric

Activity Narrative: ARV drugs, for its activities. The cost of pediatric ARV drugs is not included in MJAP's FY08 PEPFAR

funding for ARVs.

Funding for Treatment: Adult Treatment (HTXS): $2,525,400

Makerere University Faculty of Medicine was awarded a cooperative agreement titled "Provision of routine

HIV testing, counseling, basic care and antiretroviral therapy at teaching hospitals in the Republic of

Uganda" in 2004. The program named Mulago-Mbarara Teaching Hospitals' Joint AIDS Program (MJAP)

implements HIV/AIDS services in Uganda's two major teaching hospitals (Mulago and Mbarara) and their

catchment areas in close collaboration with the national programs run by the Ministry of Health (MOH).

MJAP also collaborates with the National tuberculosis and Leprosy Program (NTLP), and leverages

resources from the Global fund. MJAP provides comprehensive HIV/AIDS services including: 1) hospital-

based routine HIV testing and counseling (RTC), 2) palliative HIV/AIDS basic care, 3) integrated TB-HIV

diagnosis with treatment of TB-HIV co-infected patients, 4) ART and HIV post- exposure prophylaxis, 5)

family based care (FBC) which includes services for orphans and vulnerable children (OVC), in addition to

home-based HIV testing and prevention activities (HBHCT), and 6) capacity building for HIV prevention and

care through training of health care providers, laboratory strengthening, and establishment of satellite HIV

clinics. Mulago and Mbarara hospitals are public referral institutions with a mandate of training, service-

provision and research. Annually 3,000 health care providers are trained and about one million patients

seen in the two hospitals (500,000 outpatients and 130,000 inpatients for Mulago, and 300,000 in and

outpatients for Mbarara). Approximately 60% of medical admissions in both hospitals are because of HIV

infection and related complications. Within Mulago, MJAP works closely with the Infectious Diseases

Institute (IDI). IDI is an independent institute within the Faculty of Medicine of Makerere University with a

mission to build capacity for delivering sustainable, high-quality HIV/AIDS care, treatment and prevention in

Africa through training and research. At IDI health care providers from all over sub-Saharan Africa receive

training on HIV care and antiretroviral therapy (ART); people living with HIV receive free clinical care

including ART at the Adult Infectious Diseases Clinic (AIDC) - the clinic is integral with Mulago teaching

hospital. The main HIV clinics in Mbarara and Mulago teaching hospitals are the Mbarara ISS (HIV) clinic

and AIDC, respectively; MJAP supports HIV care and treatment in both clinics. In FY 2005 and FY 2006

MJAP opened eight satellite clinics within the catchment areas of these two clinics due to the rapidly

increasing demand for HIV/AIDS care services; increasing the total number of treatment sites to 10. The

eight satellite clinics include Mulago hospital ISS clinic, Kawempe, Naguru, Kiswa and Kiruddu (under

Kampala City Council - KCC), Mbarara municipality clinic (under the Mbarara municipal council),

Bwizibwera health center IV (under MOH and Mbarara local government), and Mulago TB/HIV clinic, which

provides care for TB-HIV co-infected patients. The satellite clinic activities are implemented in collaboration

with several partners including KCC, Mbarara Municipal Council, IDI, Baylor-Paediatric Infectious Disease

Clinic (PIDC), Protection of Families against AIDS (PREFA), MOH, and other partners.

MJAP ARV services include regular screening for ART eligibility, provision of ART drugs, promotion of

adherence to treatment, ongoing counseling on HIV prevention, care and treatment, monitoring of ART both

clinically and by laboratory, and training of health care providers. Currently, the MJAP ARV services'

activities are implemented at 10 outlets as listed above. The 10 service outlets serve over 27,000 patients in

care, 10,641 of who are on ART (4,280 at AIDC, 2,620 in Mbarara ISS clinic, 1,395 in Mulago ISS clinic,

262 in Mulago TB/HIV, 482 in Mbarara municipality clinic, 560 in Kawempe KCC, 282 in Bwizibwera HCIV,

360 in Naguru KCC and >400 in Kiswa and Kiruddu (>6326 of these receive ARVs from MOH/Global fund

support). Two additional satellite HIV/AIDS clinics will be established within Kampala district by March 2008,

in collaboration IDI and KCC increasing the number of sites to 12. The number of HIV patients in the clinics

continues to increase with the expansion of RTC in the hospitals. The AIDC and Mbarara ISS clinics provide

care for adult patients (children receive care from the PIDC and Mbarara pediatric ISS clinics). However, in

the satellite clinics MJAP collaborates with other partners to provide comprehensive HIV care to families,

including children. The two satellite clinics of Bwizibwera and Mbarara municipality offer both paediatric and

adult ART. The demand for ART is very high in all the care and treatment sites. Majority of HIV positive

patients identified through the RTC program (70%) need ARVs (WHO Stages 3 and 4 or CD4<200).

Majority of RTC recipients that are HIV infected also receive CD4 testing at baseline. The program provides

ARV services in line with national treatment guidelines. In the outpatient HIV clinics, patients undergo

orientation to prepare them for ART. Patients who fulfill the eligibility criteria receive a second orientation

meeting with their treatment supporter. ARVs are initiated on the third visit if the medical officer is satisfied

that the patient is ready to begin therapy. Patients are seen by the adherence nurse counselor on day 0,

day 15, 1 month and then monthly for counseling and ARV refills. Adherence to ARVs is monitored by self

report using a visual analogue scale, ART patient cards and pill counts (patients return the bottles with any

remaining pills). CD4 monitoring is performed at least twice a year, CBCs on a quarterly basis and

chemistries as needed. In both Mulago and Mbarara AIDS clinics, we estimate that only about 60% of

clinically eligible patients are receiving ART although the majority (70%) of HIV infected persons identified in

the ongoing RTC program are eligible for ART. MJAP has trained over 500 health care providers in the

provision of antiretroviral therapy and strengthened systems for ART delivery including staffing, laboratory

support, logistics and data management. By March 2008, the program will be providing ARVs services to an

estimated 17,000 (including 10,000 patients who receive ARVs from MOH) in terms of staffing, laboratory

and clinical monitoring.

In FY 2008 (April 2008 to March 2009), two new satellite clinics will be established in collaboration with IDI,

bringing the total to 14 sites. MJAP will provide ARV services to >25,000 patients by March 2009 (including

10,000 patients who will access ARV drugs from GFATM - Ministry of Health). To ensure sustainability,

MJAP will continue to support the improvement of existing infrastructure and systems within the facilities.

Funds will go towards additional staffing and training of new and existing staff. There will be continued use

of the core staff of the host institutions to reduce on the hiring of new personnel. MJAP will strengthen

prevention with positives counseling and support including HIV testing for spouses of patients in the HIV

clinics. The program will reinforce adherence counseling and support, and follow-up of ART patients. MJAP

will hire and train additional and existing staff and up to 200 health care providers will receive training in

ART delivery. The program will strengthen ART patient tracking and adherence support; enhance ART

treatment and HIV prevention integration in the clinics, promote prevention with positives activities and

involvement of people living with HIV/AIDS (PHA) in patient care and support. The program will provide care

for adult patients in AIDC and Mbarara ISS clinics (children receive ART from PIDC and the Mbarara

pediatric HIV clinic). In the satellite clinics, MJAP will provide comprehensive HIV/AIDS care and treatment

for families including children in partnership with other programs. Special attention shall be given to

pregnant women attending the clinics to ensure that all those who are eligible for treatment receive it. It is

expected that many pregnant women will be referred from PMTCT sites and ANC clinics. The funding for

ART services will go towards the hiring and training of health care providers, PHA and other support staff,

initiation and follow-up of patients on ART, quality assurance, support supervision and M&E.

Funding for Laboratory Infrastructure (HLAB): $900,000

Makerere University Faculty of Medicine was awarded a cooperative agreement titled "Provision of routine

HIV testing, counseling, basic care and antiretroviral therapy at teaching hospitals in the Republic of

Uganda" in 2004. The program named Mulago-Mbarara Teaching Hospitals' Joint AIDS Program (MJAP)

implements HIV/AIDS services in Uganda's two major teaching hospitals (Mulago and Mbarara) and their

catchment areas in close collaboration with the national programs run by the Ministry of Health (MOH).

MJAP also collaborates with the National tuberculosis and Leprosy Program (NTLP), and leverages

resources from the Global fund. MJAP provides comprehensive HIV/AIDS services including: 1) hospital-

based routine HIV testing and counseling (RTC), 2) palliative HIV/AIDS basic care, 3) integrated TB-HIV

diagnosis with treatment of TB-HIV co-infected patients, 4) ART and HIV post- exposure prophylaxis, 5)

family based care (FBC) which includes services for orphans and vulnerable children (OVC), in addition to

home-based HIV testing and prevention activities (HBHCT), and 6) capacity building for HIV prevention and

care through training of health care providers, laboratory strengthening, and establishment of satellite HIV

clinics. Mulago and Mbarara hospitals are public referral institutions with a mandate of training, service-

provision and research. Annually 3,000 health care providers are trained and about one million patients

seen in the two hospitals (500,000 outpatients and 130,000 inpatients for Mulago, and 300,000 in and

outpatients for Mbarara). Approximately 60% of medical admissions in both hospitals are because of HIV

infection and related complications. Within Mulago, MJAP works closely with the Infectious Diseases

Institute (IDI). IDI is an independent institute within the Faculty of Medicine of Makerere University with a

mission to build capacity for delivering sustainable, high-quality HIV/AIDS care, treatment and prevention in

Africa through training and research. At IDI health care providers from all over sub-Saharan Africa receive

training on HIV care and antiretroviral therapy (ART); people living with HIV receive free clinical care

including ART at the Adult Infectious Diseases Clinic (AIDC) - the clinic is integral with Mulago teaching

hospital. The main HIV clinics in Mbarara and Mulago teaching hospitals are the Mbarara ISS (HIV) clinic

and AIDC, respectively; MJAP supports HIV care and treatment in both clinics. In FY 2005 and FY 2006

MJAP opened eight satellite clinics within the catchment areas of these two clinics due to the rapidly

increasing demand for HIV/AIDS care services; increasing the total number of treatment sites to 10. The

eight satellite clinics include Mulago hospital ISS clinic, Kawempe, Naguru, Kiswa and Kiruddu (under

Kampala City Council - KCC), Mbarara municipality clinic (under the Mbarara municipal council),

Bwizibwera health center IV (under MOH and Mbarara local government), and Mulago TB/HIV clinic, which

provides care for TB-HIV co-infected patients. The satellite clinic activities are implemented in collaboration

with several partners including KCC, Mbarara Municipal Council, IDI, Baylor-Pediatric Infectious Disease

Clinic (PIDC), Protection of Families against AIDS (PREFA), MOH, and other partners.

MJAP HIV care and treatment laboratory activities are currently implemented at the 10 sites listed above.

By March 2008, 12 clinics will be operational and providing palliative basic care (an additional two satellite

clinics will be opened in collaboration with KCC and IDI). Three regional referral hospitals will also be

supported to implement TB and HIV screening. Up to 40,000 patients will access laboratory services

through MJAP support at the 12 HIV clinics. The number of HIV patients in the clinics continues to increase

with the expansion of RTC in the hospitals. In FY 2006 and FY 2007, MJAP strengthened the Mulago and

Mbarara laboratory infrastructure. The program procured two fFacs caliburs (for CD4 testing), haematology

and chemistry machines for the Mulago hospital laboratory; these machines support five Kampala based

HIV care and treatment sites and have significantly reduced the costs for HIV treatment monitoring tests.

MJAP also procured a Facs Count, haematology and chemistry machine for the Mbarara Municipality Clinic.

The program procured two ELISA machines for HIV testing and microscopes for TB and malaria diagnosis;

microscopes have been procured for all satellite clinic laboratories and the three regional referral hospitals.

The program provides supplies and maintenance of all the equipment. The Elisa testing for in-patients has

reduced demand for rapid HIV test kits. MJAP has also trained laboratory technicians and hired additional

staff to enhance HIV diagnosis and laboratory monitoring for patients on treatment. In Mbarara,

collaboration with The AIDS Support Organisation (TASO) and the Italian Cooperation-supported laboratory

has ensured ART laboratory monitoring for the Mbarara satellite care and treatment sites. TB diagnostics

and quality management are implemented in collaboration with NTLP and MOH.

In FY 2008 (April 2008 to March 2009), two new satellite care and treatment sites will be opened (increasing

the number of treatment sites to 14), and RTC-TB diagnosis will expand to two (2) additional regional

referral hospitals. MJAP will provide ART laboratory screening and monitoring support to > 25,000 patients

(including 15,000 accessing Global Fund ARV drugs). To ensure sustainability, MJAP will continue to

support the improvement of existing infrastructure and systems within the facilities. Funds will go towards

additional staffing, training and support for laboratory monitoring including CD4 counts. Our aim is to have

14 units with capacity to provide HIV testing malaria diagnosis, TB sputum microscopy, syphilis testing, and

to improve capacity of the two hospital laboratories (Mulago and Mbarara) in CD4 and lymphocyte counts

and chemistry (liver and renal function tests). We will also equip the laboratories in the five regional referral

hospitals to provide HIV testing and TB sputum microscopy as the RTC-TB diagnosis program expands.

The program will train new and existing staff to support the laboratories - 70 people will be trained in the

coming year. This program will strengthen the laboratory infrastructure in Mulago and Mbarara teaching

hospitals in order to provide quality ART services at the two hospitals, and the satellite clinics including

adults and children. The laboratory funding will cover the purchase of equipment and supplies, recruitment

of additional personnel, training of new and existing laboratory staff, and will enhance laboratory quality

assurance systems. In Mbarara hospital, MJAP will continue to collaborate with partners including JCRC

and the Italian cooperation who are also providing laboratory support to the hospital, to ensure existing gaps

are filled without duplication of activities, and access by all patients who require these services.

Subpartners Total: $875,000
Ministry of Health - Uganda: $400,000
Central Public Health Laboratories: $150,000
STI Clinic: $325,000