Detailed Mechanism Funding and Narrative

Years of mechanism: 2008 2009

Details for Mechanism ID: 9692
Country/Region: Nigeria
Year: 2009
Main Partner: AIDS Prevention Initiative in Nigeria, LTD
Main Partner Program: Nigeria
Organizational Type: NGO
Funding Agency: HHS/CDC
Total Funding: $12,325,958

Funding for Biomedical Prevention: Prevention of Mother to Child Transmission (MTCT): $585,800

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

In COP09, the Harvard University plans to move over 4 of its PEPFAR supported sites to APIN, Ltd (APIN).

The sites include Lagos University Teaching Hospital, Nigerian Institute of Medical Research, Onikan

Women's Hospital, and Mushin General Hospital. The activity narrative reflects the transfer of targets from

Harvard to APIN. The activities will build on the structure and systems put in place through Harvard. APIN

will maintain a strong collaboration with Harvard University.

NARRATIVE:

In COP08 APIN supported PMTCT in 2 sites. In COP09 funding will support 4 additional sites, providing a

comprehensive PMTCT program in line with the revised National PMTCT Guidelines (2007), for a total of 6

service outlets in 3 states (Lagos, Ogun and Oyo). This consists of 2 tertiary, 3 secondary and 1 primary

(PHC) sites. "Opt-out" testing and counseling with same-day test results will be provided to all pregnant

women presenting for antenatal care (ANC) and labor and delivery (L&D). The current level of PMTCT

counseling and testing uptake from women presenting for ANC or L&D is 90%. All women are provided post

-test counseling services on prevention of HIV infection, including the risks of MTCT. They are encouraged

to bring partners and family members for onsite HCT. The program has a target of providing HCT to

pregnant women with 14,200 receiving results. PMTCT prophylaxis will be provided to approximately 852

women in line with the national guidelines. In addition, APIN will provide basic care and ARV prophylaxis to

852 HIV-exposed infants. Infant follow-up care linked with PMTCT activities includes nutritional counseling

and support, growth monitoring, cotrimoxazole prophylaxis and other preventative care services. Early

Infant Diagnosis (EID) will be carried out using dried blood spots (DBS) in line with the national EID scale up

plan.

Through this program area, APIN will provide linkages to other prevention, care and treatment services. All

ART-ineligible women will be placed on zidovudine from 28 weeks and or zidovudine and lamivudine from

34/36 weeks until delivery and will be enrolled into basic care services at the time they access PMTCT

services. Following delivery, mothers will be monitored in the care and treatment program, where services

include onsite enrollment or referrals for family planning and other reproductive health services. In addition,

PMTCT services are integrated into a system of maternal and child services designed to promote maternal

and child health for all women. All ART-eligible pregnant women will be provided with ART through the adult

care and treatment program area in line with national guidelines. Children who become HIV-infected during

the time they are being monitored as part of the PMTCT program will be linked to the pediatric care and

treatment program. Those HIV-exposed children placed on single dose nevirapine at birth and zidovudine

for 6 weeks and who remain uninfected at 18-months following the completion of ARV prophylaxis will be

linked to the OVC program for continued services.

Counseling on infant feeding options occurs during the antenatal period, at L&D, and throughout infant

follow-up and is done according to the National PMTCT and Infant Feeding Guidelines. Infant feeding

counseling will be performed in an unbiased manner and women will be supported in their choice of

method. Clients will also be counseled on the beneficial effect of couple/partner HCT/disclosure on

adherence to infant feeding choice. A follow-up team consisting of counselors and a home-based care

(HBC) support group of PLWHAs will assist in home and community tracking of positive mothers to provide

nutritional support and ascertain infant diagnosis. This funding will support the ANC, labs, ARV prophylaxis

intervention to mothers and babies (not ART), and training of personnel involved in PMTCT.

A regular training program will be established at all sites to train and retrain 111 personnel involved in the

PMTCT program using the National PMTCT Guidelines. This includes non-laboratory personnel who will be

trained in HIV counseling and testing and traditional birth attendants (TBAs) using an adapted curriculum in

local areas near sites in PMTCT counseling. PMTCT counselors in the National PMTCT Program will also

be trained. APIN Ltd will provide technical assistance for the development of the National Infant Feeding

Counseling Manual and will subsequently conduct a zonal training of trainers with this manual.

During COP09, APIN will scale up the Harvard initiated quality assurance/quality improvement (QA/QI)

activities to the APIN-supported PMTCT sites. The program will also continue to monitor and utilize

electronic data captured through SI activities to measure the quality of services provided as well as the

associated patient outcomes.

APIN will partner with Harvard and other implementing partners (IPs) in the implementation of the PEPFAR-

Nigeria local government area (LGA) coverage strategy in the program areas of PMTCT, OVC and TB/HIV,

designed to ensure the provision of PMTCT and TB/HIV services in at least one health facility in each LGA

of Oyo state. Under the coverage strategy, these facilities are all linked with primary health facilities, which

provide HCT and referrals for PMTCT services for HIV-infected mothers.

EMPHASIS AREAS

This activity will place emphasis on the development of networks through expansion into more local areas

through a network of secondary or primary PMTCT clinics, with rural outreach to community healthcare

workers and TBAs involved in home delivery. All community workers and TBAs with whom APIN works are

linked to tertiary health care facilities. In addition, major emphasis will be placed on building organizational

capacity in order to work towards sustainability of PMTCT centers. These system strengthening activities

are led by local investigators at current PMTCT sites who participate in new site assessments, overseeing

QA/QI, capacity development and training for new PMTCT centers. Emphasis is also placed on performing

targeted evaluations of PMTCT interventions in line with National guidelines to estimate the rate of

transmission with each of the ARV prophylaxis regimens used.

POPULATIONS BEING TARGETED

In addition to providing PMTCT services to pregnant women that know their HIV infection status, this

program also targets women who may not know their HIV status and may be at greater risk for MTCT.

Furthermore, it targets infants who are most at risk of becoming infected from an HIV positive mother during

the antepartum, intrapartum and postpartum periods. Through the counseling and testing program area,

Activity Narrative: APIN seeks to target a broader group of adults by encouraging women to bring their partners and family

members in for HCT. Furthermore, training activities will train public and private health care workers on the

implementation of PMTCT protocols and HIV-related laboratory testing.

CONTRIBUTIONS TO OVERALL PROGRAM AREA

Through the PMTCT program, APIN will provide counseling and testing with test results to 14,200 pregnant

women. Additionally, treatment and prophylaxis will be provided to 852 pregnant women. Implementation of

the National PMTCT Guidelines in 6 sites contributes to the PEPFAR goal of expanding ART and PMTCT

services. Counseling will encourage mothers to bring their partners and family members for testing to reach

discordant couples and expand the reach of HCT. This program is implemented in geographically

networked sites to optimize training efforts and provide collaborative clinic/lab services as needed. APIN will

train and retrain 111 health care personnel from the PMTCT sites, including doctors, nurses, pharmacists

and counselors. Training will build capacity at local sites to implement PMTCT programs and provide

essential treatment support to pregnant women with HIV/AIDS. Capacity building efforts are aimed at future

expansions of PMTCT programs. QA/QI will be carried out through personnel training, data collection from

sites for monitoring and evaluation and supervisory visits from key program management staff, which may

include representatives from the USG and government of Nigeria (GON).

The program will increase gender equity by specifically targeting pregnant females for HCT and PMTCT

prophylaxis and their male partners for HCT. Data collection on PMTCT regimens in line with the National

guidelines provides a basis for developing strategies to ensure that all pregnant women have access to

needed and optimally effective PMTCT services. This program addresses stigma and male norms and

behaviors through the encouragement of partner notification and bringing other family members in for HCT.

Infant feeding counseling, including on the appropriate use of exclusive breastfeeding or exclusive use of

breast milk substitute (BMS) where AFASS is available, will be in line with the National PMTCT Guidelines.

Referrals to income generating activities (IGAs) will also be provided to women as a part of palliative care

and counseling activities.

LINKS TO OTHER ACTIVITIES

This activity is also linked to counseling and testing, OVC, adult and pediatric care and treatment, sexual

prevention, biomedical prevention, SI and gender. Pregnant women who present for HCT services will be

provided with information about the PMTCT program and referred to the PMTCT program if they are eligible

for these services. ART services for HIV-infected infants and mothers will be provided through adult and

pediatric treatment services. Basic pediatric care and support, including support for chosen feeding option

and TB care, is provided for all infants and children through pediatric care and treatment and OVC activities;

all exposed infants identified through PMTCT services will be linked to these OVC services. Pregnant

women are at high risk for requiring blood transfusion. Personnel involved in patient care will be trained in

universal precautions as a part of injection safety activities. Additionally, these activities are linked to SI,

which provides support for monitoring and evaluation of the PMTCT activities and QA/QI initiatives.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22510

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22510 22510.08 HHS/Centers for AIDS Prevention 9692 9692.08 $225,000

Disease Control & Initiative, LTD

Prevention

Emphasis Areas

Gender

* Addressing male norms and behaviors

* Increasing gender equity in HIV/AIDS programs

* Reducing violence and coercion

Health-related Wraparound Programs

* Child Survival Activities

* Malaria (PMI)

* Safe Motherhood

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $28,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.01:

Funding for Sexual Prevention: Abstinence/Be Faithful (HVAB): $88,948

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

In COP09, the Harvard School of Public Health (Harvard) plans to move over four of its PEPFAR supported

sites to APIN, Ltd (APIN). The sites include Lagos University Teaching Hospital (LUTH), Nigerian Institute

of Medical Research (NIMR), Onikan Women's Hospital (OWH), and Mushin General Hospital (MGH). The

activity narrative reflects the transfer of targets from Harvard to APIN. The activities will build on the

structure and systems put in place through Harvard. APIN will maintain a strong collaboration with Harvard

University. Since HVAB and HVOP activities are combined, the narratives for the 2 corresponding sections

have been merged.

During COP08, APIN assumed management responsibility for 2 sites (Sacred Heart Catholic Hospital in

Lantoro, Ogun State and Primary Health Center-Iru on Victoria Island, Lagos) and is adding 4 additional

sites (LUTH, NIMR, OWH, and MGH) during COP09. APIN will continue sexual prevention programming

activities at all 6 sites in line with the overall PEPFAR Nigeria goal of providing a comprehensive package of

prevention services to individuals reached, thereby improving the effectiveness of this messaging, through a

balanced portfolio of prevention activities, including abstinence and be faithful messaging (AB) along with

condoms and other prevention (C&OP; ABC in combination). APIN will assist PEPFAR Nigeria in extending

its reach of ABC services through the APIN supported sites. Through its other program areas, APIN has a

large population of HIV-positive adults, adolescents and children to which it is already providing services;

this group forms part of the core target population for age appropriate ABC messaging that is provided by

APIN through its prevention with positives (PwP) activities including sexually-transmitted infection (STI)

screening and management, condom provision, sexual risk reduction, disclosure, adherence, reduction of

alcohol consumption, and testing of sex partners and children in the HIV clinic setting. In addition, APIN will

target activities to HIV-negative persons in its catchment areas in order to minimize their risk behaviors and

contribute to an overall reduction in HIV prevalence.

In COP09, APIN will implement ABC activities at both the facility and community levels utilizing the

minimum prevention package strategy as contained in the National Prevention Plan. This package includes:

1) community outreach campaigns; 2) peer education; 3) infection control activities; and 4) STI

management/treatment. The goal of the program is to focus on targeted communities and saturate those

communities with messages conveyed in multiple fora. Utilizing such a methodology, a large number of

people will be reached with messages received via one method or another; however, the target group will

be those individuals that will have received C&OP messaging: (1) on a regular basis; and, (2) via at least 3

of the 4 strategies employed by APIN.

AB activities conducted at the local level by APIN will be reinforced through national-level mass media

campaigns by other USG partners, such as the successful Zip-Up campaign. AB messages promoting

abstinence and mutual fidelity, and addressing issues of concurrent and multiple sexual partnerships will be

balanced with concurrent condoms and other prevention messaging, where appropriate and will be

integrated with treatment and care services in our 6 sites.

A key age group for AB activities is youth/young adults aged 15-24 years as this encompasses the highest

prevalence age group. This age cohort, for both men and women, represents the working age group in

Nigeria; it is expected that a combination of prevention messaging approaches will ensure they are reached

with appropriate interventions.

APIN will collaborate with community-based organizations (CBOs) and PLWHA support groups at its

facilities and surrounding communities in other PEPFAR programming activities. These support groups will

utilize peer education model and community awareness campaigns to disseminate ABC messaging to other

PLWHA and to wider audiences. Support group activities will include the dissemination of prevention

information for HIV-infected individuals (funded under basic care and support) as well as community

outreach to high-risk populations to encourage HIV counseling and testing (HCT) and healthy behaviors,

including recommendations for partner notification and condom use. For HIV-negative individuals, trained

counselors will provide education on HIV/AIDS transmission, risks, and risk reduction strategies including

HIV testing.

A community awareness strategy will also be employed to serve catchment areas of the hospital facilities,

which will be linked with community mobilization efforts promoting HCT. During static and mobile HCT

services, counselors will be disseminating balanced ABC messages to recipient communities and clients

through focused group discussions and interpersonal communication. Key messages that will be conveyed

include: delay in sexual debut, secondary abstinence, mutual fidelity, prompt and complete treatment of all

STIs, and promotion of need to ascertain HIV serostatus through HCT.

APIN sites will target most at risk populations (MARPs), including outpatient STI patients, border traders,

young male market agents, and motor mechanics. APIN's HCT site at PHC-Iru on Victoria Island serves the

Kuramo area, a community with a large number of MARPs where most residents are sex- and bar-workers,

and have HIV prevalence greater than 60%. Prevention activities at these clinics provide condoms and

educational materials targeting the risks faced by this population in particular. In addition to comprehensive

counseling on HIV prevention and risk reduction, HIV-infected individuals identified through this activity will

be referred for palliative care and evaluation for ART eligibility. An emphasis on men with high-risk

behaviors through these community-based efforts will also enhance prevention efforts and facilitate access

to their partners.

A focus of the program in COP09 will be continued improvement of the integration of prevention activities

into the HIV care and treatment settings; specifically, healthcare providers and lay counselors in care and

treatment settings will be trained to appropriately deliver integrated ABC prevention messages and

incorporate the messages into routine clinic visits using IEC materials and job aids. An appropriate balance

of ABC will be tailored to the needs and social situation of each individual client in its presentation. In

addition to the integration of such services into the HIV-specific treatment setting, prevention activities will

be assimilated into other points of service in each health facility (general outpatient clinics, emergency

services, etc.), particularly into reproductive health services including family planning counseling, STI

Activity Narrative: management and counseling, and risk-reduction counseling.

This funding will also be used to support the procurement and distribution of written prevention messages

and condoms. The materials will provide patients and clients with HIV prevention information using the

"ABC" model, including information about healthy behaviors, safer sexual practices, PMTCT, and condom

usage. Prevention messages will also include information about other STIs. Condoms will be offered to all

individuals at all sites and will be provided to APIN by the Society for Family Health (SFH).

The target for the AB messaging campaign is 3,645 individuals. In addition, age-appropriate abstinence

only messaging and secondary abstinence messaging will be conveyed to children and adolescents,

particularly focused on those orphans and vulnerable children receiving both facility- and home-based

support. The target for this intensive activity campaign (condom and other prevention) is 7,197 individuals.

Additional staffing and training of counselors will also be provided by this funding, including a dedicated full-

time staff person. This activity will provide support for training of 112 individuals in AB messaging. An

additional 99 individuals will be trained to promote HIV/AIDS prevention through other behavior change

beyond abstinence and/or being faithful, including condom promotion and STD prevention.

EMPHASIS AREAS

ABC programming emphasizes local organization capacity building, human capacity development and

efforts to increase gender equity in HIV/AIDS programs. These activities also promote a rights-based

approach to prevention among positives and other vulnerable members of society and equal access to

information and services. Reduction of stigma and discrimination are also key to the program. Through ABC

activities, we place major emphasis on community mobilization and participation, as an element of outreach

for prevention efforts. Additionally, we place major emphasis on training as well as infrastructure and human

resources in order to build the capacity of counselors and providers in a full range of prevention strategies.

We also reinforce that information, education and communication are essential elements of outreach to high

-risk populations, and that developing networks for linking these activities to HCT, PMTCT, and other ART

activities serves as a source of prevention information.

These activities address gender equity issues by providing equal access to prevention services for men and

women. In some cases, our activities seek to target men who may be at high risk for HIV in order to

promote condom use as a means of prevention and access to services for their sexual partners. Male-

targeted counseling seeks to address male norms and behaviors in order to encourage safer sexual

practices. Strong prevention programs that accommodate the array of societal and cultural norms can also

help reduce stigma and discrimination. The provision of such services at the community level will serve as

an important platform from which general HIV/AIDS information can be provided and risk reduction

strategies discussed.

POPULATIONS TARGETED:

Key populations targeted are the healthcare community in treatment facilities, PLWHA, youths and adults

accessing HCT services at either static or mobile within catchment areas of the treatment sites, high-risk

populations, support group members and immediate families of PLWHA. Other target populations include

discordant couples, pregnant women and religious leaders. Targeting these populations is important to

encourage safe sexual practices, HCT and other prevention measures. Health care workers will also be

targeted for training on the most effective prevention measures for various risk groups.

CONTRIBUTION TO OVERALL PROGRAM AREA

These prevention activities are consistent with PEPFAR's goals for Nigeria, which aim to support a number

of prevention strategies as a comprehensive prevention package. In order to be maximally effective, the

prevention messages developed at different sites will be tightly targeted to various high-risk groups that they

serve. Furthermore, these activities are consistent with the PEPFAR 5-year strategy, which seeks to scale-

up prevention services, build capacity for long-term prevention programs, and encourage testing and

targeted outreach to high-risk populations. The establishment of networks and referral systems from

prevention efforts at the community level to PMTCT and HIV care and treatment will help facilitate the scale-

up of the overall program. Additionally, the long term sustainability of the prevention portfolio is more

assured as APIN, a Nigerian organization, assumes management responsibility for more sites previously

managed by Harvard.

LINKS TO OTHER ACTIVITIES:

ABC activities relate to HCT, by increasing awareness of HIV. They also relate to adult and pediatric care

and support activities through dissemination of information by home-based care providers and ultimately by

decreasing demand on care services through decreased prevalence. Linkages also exist to OVC

programming by targeting OVC. The provision of such services at the community level will serve as an

important platform from which general HIV/AIDS information can be provided and risk reduction strategies

discussed. This program area also links to Strategic Information (SI) as all progress will be monitored by the

SI programming and to Gender as specific programs will be targeted to be gender-appropriate.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22511

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22511 22511.08 HHS/Centers for AIDS Prevention 9692 9692.08 $90,000

Disease Control & Initiative, LTD

Prevention

Emphasis Areas

Gender

* Addressing male norms and behaviors

* Increasing gender equity in HIV/AIDS programs

Health-related Wraparound Programs

* Family Planning

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $64,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.02:

Funding for Sexual Prevention: Other Sexual Prevention (HVOP): $254,715

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

In COP09, the Harvard School of Public Health (Harvard) plans to move over four of its PEPFAR supported

sites to APIN, Ltd (APIN). The sites include Lagos University Teaching Hospital (LUTH), Nigerian Institute

of Medical Research (NIMR), Onikan Women's Hospital (OWH), and Mushin General Hospital (MGH). The

activity narrative reflects the transfer of targets from Harvard to APIN. The activities will build on the

structure and systems put in place through Harvard. APIN will maintain a strong collaboration with Harvard

University. Since HVAB and HVOP activities are combined, the narratives for the 2 corresponding sections

have been merged.

During COP08, APIN assumed management responsibility for 2 sites (Sacred Heart Catholic Hospital in

Lantoro, Ogun State and Primary Health Center-Iru on Victoria Island, Lagos) and is adding 4 additional

sites (LUTH, NIMR, OWH, and MGH) during COP09. APIN will continue sexual prevention programming

activities at all 6 sites in line with the overall PEPFAR Nigeria goal of providing a comprehensive package of

prevention services to individuals reached, thereby improving the effectiveness of this messaging, through a

balanced portfolio of prevention activities, including abstinence and be faithful messaging (AB) along with

condoms and other prevention (C&OP; ABC in combination). APIN will assist PEPFAR Nigeria in extending

its reach of ABC services through the APIN supported sites. Through its other program areas, APIN has a

large population of HIV-positive adults, adolescents and children to which it is already providing services;

this group forms part of the core target population for age appropriate ABC messaging that is provided by

APIN through its prevention with positives (PwP) activities including sexually-transmitted infection (STI)

screening and management, condom provision, sexual risk reduction, disclosure, adherence, reduction of

alcohol consumption, and testing of sex partners and children in the HIV clinic setting. In addition, APIN will

target activities to HIV-negative persons in its catchment areas in order to minimize their risk behaviors and

contribute to an overall reduction in HIV prevalence.

In COP09, APIN will implement ABC activities at both the facility and community levels utilizing the

minimum prevention package strategy as contained in the National Prevention Plan. This package includes:

1) community outreach campaigns; 2) peer education; 3) infection control activities; and 4) STI

management/treatment. The goal of the program is to focus on targeted communities and saturate those

communities with messages conveyed in multiple fora. Utilizing such a methodology, a large number of

people will be reached with messages received via one method or another; however, the target group will

be those individuals that will have received C&OP messaging: (1) on a regular basis; and, (2) via at least 3

of the 4 strategies employed by APIN.

AB activities conducted at the local level by APIN will be reinforced through national-level mass media

campaigns by other USG partners, such as the successful Zip-Up campaign. AB messages promoting

abstinence and mutual fidelity, and addressing issues of concurrent and multiple sexual partnerships will be

balanced with concurrent condoms and other prevention messaging, where appropriate and will be

integrated with treatment and care services in our 6 sites.

A key age group for AB activities is youth/young adults aged 15-24 years as this encompasses the highest

prevalence age group. This age cohort, for both men and women, represents the working age group in

Nigeria; it is expected that a combination of prevention messaging approaches will ensure they are reached

with appropriate interventions.

APIN will collaborate with community-based organizations (CBOs) and PLWHA support groups at its

facilities and surrounding communities in other PEPFAR programming activities. These support groups will

utilize peer education model and community awareness campaigns to disseminate ABC messaging to other

PLWHA and to wider audiences. Support group activities will include the dissemination of prevention

information for HIV-infected individuals (funded under basic care and support) as well as community

outreach to high-risk populations to encourage HIV counseling and testing (HCT) and healthy behaviors,

including recommendations for partner notification and condom use. For HIV-negative individuals, trained

counselors will provide education on HIV/AIDS transmission, risks, and risk reduction strategies including

HIV testing.

A community awareness strategy will also be employed to serve catchment areas of the hospital facilities,

which will be linked with community mobilization efforts promoting HCT. During static and mobile HCT

services, counselors will be disseminating balanced ABC messages to recipient communities and clients

through focused group discussions and interpersonal communication. Key messages that will be conveyed

include: delay in sexual debut, secondary abstinence, mutual fidelity, prompt and complete treatment of all

STIs, and promotion of need to ascertain HIV serostatus through HCT.

APIN sites will target most at risk populations (MARPs), including outpatient STI patients, border traders,

young male market agents, and motor mechanics. APIN's HCT site at PHC-Iru on Victoria Island serves the

Kuramo area, a community with a large number of MARPs where most residents are sex- and bar-workers,

and have HIV prevalence greater than 60%. Prevention activities at these clinics provide condoms and

educational materials targeting the risks faced by this population in particular. In addition to comprehensive

counseling on HIV prevention and risk reduction, HIV-infected individuals identified through this activity will

be referred for palliative care and evaluation for ART eligibility. An emphasis on men with high-risk

behaviors through these community-based efforts will also enhance prevention efforts and facilitate access

to their partners.

A focus of the program in COP09 will be continued improvement of the integration of prevention activities

into the HIV care and treatment settings; specifically, healthcare providers and lay counselors in care and

treatment settings will be trained to appropriately deliver integrated ABC prevention messages and

incorporate the messages into routine clinic visits using IEC materials and job aids. An appropriate balance

of ABC will be tailored to the needs and social situation of each individual client in its presentation. In

addition to the integration of such services into the HIV-specific treatment setting, prevention activities will

be assimilated into other points of service in each health facility (general outpatient clinics, emergency

services, etc.), particularly into reproductive health services including family planning counseling, STI

Activity Narrative: management and counseling, and risk-reduction counseling.

This funding will also be used to support the procurement and distribution of written prevention messages

and condoms. The materials will provide patients and clients with HIV prevention information using the

"ABC" model, including information about healthy behaviors, safer sexual practices, PMTCT, and condom

usage. Prevention messages will also include information about other STIs. Condoms will be offered to all

individuals at all sites and will be provided to APIN by the Society for Family Health (SFH).

The target for the AB messaging campaign is 3,645 individuals. In addition, age-appropriate abstinence

only messaging and secondary abstinence messaging will be conveyed to children and adolescents,

particularly focused on those orphans and vulnerable children receiving both facility- and home-based

support. The target for this intensive activity campaign (condom and other prevention) is 7,197 individuals.

Additional staffing and training of counselors will also be provided by this funding, including a dedicated full-

time staff person. This activity will provide support for training of 112 individuals in AB messaging. An

additional 99 individuals will be trained to promote HIV/AIDS prevention through other behavior change

beyond abstinence and/or being faithful, including condom promotion and STD prevention.

EMPHASIS AREAS

ABC programming emphasizes local organization capacity building, human capacity development and

efforts to increase gender equity in HIV/AIDS programs. These activities also promote a rights-based

approach to prevention among positives and other vulnerable members of society and equal access to

information and services. Reduction of stigma and discrimination are also key to the program. Through ABC

activities, we place major emphasis on community mobilization and participation, as an element of outreach

for prevention efforts. Additionally, we place major emphasis on training as well as infrastructure and human

resources in order to build the capacity of counselors and providers in a full range of prevention strategies.

We also reinforce that information, education and communication are essential elements of outreach to high

-risk populations, and that developing networks for linking these activities to HCT, PMTCT, and other ART

activities serves as a source of prevention information.

These activities address gender equity issues by providing equal access to prevention services for men and

women. In some cases, our activities seek to target men who may be at high risk for HIV in order to

promote condom use as a means of prevention and access to services for their sexual partners. Male-

targeted counseling seeks to address male norms and behaviors in order to encourage safer sexual

practices. Strong prevention programs that accommodate the array of societal and cultural norms can also

help reduce stigma and discrimination. The provision of such services at the community level will serve as

an important platform from which general HIV/AIDS information can be provided and risk reduction

strategies discussed.

POPULATIONS TARGETED:

Key populations targeted are the healthcare community in treatment facilities, PLWHA, youths and adults

accessing HCT services at either static or mobile within catchment areas of the treatment sites, high-risk

populations, support group members and immediate families of PLWHA. Other target populations include

discordant couples, pregnant women and religious leaders. Targeting these populations is important to

encourage safe sexual practices, HCT and other prevention measures. Health care workers will also be

targeted for training on the most effective prevention measures for various risk groups.

CONTRIBUTION TO OVERALL PROGRAM AREA

These prevention activities are consistent with PEPFAR's goals for Nigeria, which aim to support a number

of prevention strategies as a comprehensive prevention package. In order to be maximally effective, the

prevention messages developed at different sites will be tightly targeted to various high-risk groups that they

serve. Furthermore, these activities are consistent with the PEPFAR 5-year strategy, which seeks to scale-

up prevention services, build capacity for long-term prevention programs, and encourage testing and

targeted outreach to high-risk populations. The establishment of networks and referral systems from

prevention efforts at the community level to PMTCT and HIV care and treatment will help facilitate the scale-

up of the overall program. Additionally, the long term sustainability of the prevention portfolio is more

assured as APIN, a Nigerian organization, assumes management responsibility for more sites previously

managed by Harvard.

LINKS TO OTHER ACTIVITIES:

ABC activities relate to HCT, by increasing awareness of HIV. They also relate to adult and pediatric care

and support activities through dissemination of information by home-based care providers and ultimately by

decreasing demand on care services through decreased prevalence. Linkages also exist to OVC

programming by targeting OVC. The provision of such services at the community level will serve as an

important platform from which general HIV/AIDS information can be provided and risk reduction strategies

discussed. This program area also links to Strategic Information (SI) as all progress will be monitored by the

SI programming and to Gender as specific programs will be targeted to be gender-appropriate.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22512

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22512 22512.08 HHS/Centers for AIDS Prevention 9692 9692.08 $50,000

Disease Control & Initiative, LTD

Prevention

Emphasis Areas

Gender

* Addressing male norms and behaviors

* Increasing gender equity in HIV/AIDS programs

Health-related Wraparound Programs

* Family Planning

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $32,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.03:

Funding for Care: Adult Care and Support (HBHC): $1,447,947

Several new CDC partners have recently been identified through a competetive funding opportunity

announcement as approved under COP08. Many of these partners are new to the PEPFAR and/or CDC

planning and implementation processes. The amounts awarded differ significantly from the original

proposal amounts submitted by these new partners. The difference now requires the new partners, working

in conjunction with the in-country CDC office and interagency technical working groups, to revise the action

plans for FY08 and FY09. CDC is currently working closely with the new partners to assure their effective

understanding of the PEPFAR planning process and that action plans for FY08 and FY09 COP submissions

are in accordance with funding awards as well as PEPFAR goals and objectives. Detailed narrative

changes will be submitted in the January 2009 reprogramming submission.

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

In COP09, the Harvard School of Public Health (Harvard) plans to move four of the HSPH PEPFAR

supported sites to APIN Ltd. (APIN). The sites include Lagos University Teaching Hospital, Nigerian

Institute of Medical Research, Onikan Women's Hospital, and Mushin General Hospital. This activity

narrative reflects the transfer of targets from Harvard to APIN. The activities will build on the structure and

systems put in place through Harvard. APIN will maintain a strong collaboration with Harvard.

ACTIVITY DESCRIPTION

In COP08 APIN+ provided comprehensive adult care and treatment (ACT) services in 1 site and care and

support at a second site. In COP09, APIN will take over the provision of high quality ARV and basic care

and support services to eligible adult patients at a total of 6 sites; 5 comprehensive ART sites (2, tertiary

and 3 secondary facilities and 1 PHC located in three states of Lagos and Ogun. This will provide ART

services to a total of 13100 adults (8200 new) at the end of the reporting period. Facility-based palliative

care services will be provided to approximately 8250 ART ineligible PLWHA and 13100 ART eligible

PLWHA making a total of 21350 PLWHA clients. People Affected By HIV/AIDS (PABAs) will be reached

through the community and home based care (HBC) of the PLWHA clients.

Patients are identified through HCT services. All HIV-infected individuals are clinically pre-assessed for

eligibility for ARV treatment (ART). Patients who are ineligible for ART are provided with continuous clinical

monitoring and basic care and support services. ART-eligible patients are provided with ART services, in

accordance with a standardized programmatic protocol, which follows the current National ART guidelines.

All HIV+ patients are provided with palliative care services, which are consistent with the Nigerian Palliative

Care Guidelines. A network model of care will be used for service delivery.

ART-ineligible individuals that are enrolled in care will have periodic follow-up to identify changes in

eligibility status. Scheduled physician visits for all are at 3, 6, and 12 months and every 6 months thereafter.

ART patients follow the same clinical visit schedule with more intensified monitoring and pick up drugs

monthly. For all patients, at each visit, clinical exams, hematology, chemistry, viral load, and CD4

enumeration are performed when indicated. All tertiary site labs perform the necessary lab assays.

Secondary and primary sites with limited lab capability send samples to an affiliated tertiary site lab for

analysis. Electronic clinic and lab records provide data for high quality patient care and centrally coordinated

program monitoring. As additional medical needs of patients are identified through clinic visits, they will be

provided with clinical services by clinicians or referred for specialty care as necessary. HIV+ individuals will

be provided with cotrimoxazole prophylaxis according to national guidelines. Diagnostics for common OIs

may include bacterial infections, fungal infections, and protozoal infections. All HIV+ patients will be also

symptomatically screened for TB and confirmed with laboratory and radiological diagnostics as indicated

APIN will support integration of syndromic management of STIs and risk reduction interventions into care.

All PLWHA will be provided with a basic care kit including clean water kits, ITN, and IEC materials on

positive living. Pain assessment will also be conducted by clinicians and HBC providers and analgesics will

be provided. Commodities distributed as a part of the palliative care services are procured centrally through

the APIN Abuja program office and APIN Central Medical Stores in Lagos. Distribution of commodities to

individual sites is coordinated through supply chain mechanisms in place for laboratory test kits and ART

drugs. During COP09, APIN will collaborate with Harvard and SCMS for the procurement and distribution of

specified OI drugs.

Activities will also focus on PWP services. All enrolled into care will receive risk assessment and behavioral

counseling to achieve risk reduction. Condoms will also be provided to prevent STIs and re-infection.

Patients are also encouraged to refer family members for HCT. ART patients are provided ART education &

adherence counseling prior to and during ART provision, which follows the National Curriculum for

Adherence Counseling. ART patients are encouraged to have a treatment support partner to whom he/she

had disclosed status to improve adherence and to optimize care.

APIN will encourage support groups and CBOs to mobilize communities to provide HBC services. Site HBC

activities will be supervised by a hospital team. Facility-based and community-based HBC teams partner to

provide a continuum of HBC services depending on client needs. When ART patients miss scheduled clinic

visits or bed ridden clients are reported by the community HBC team, the site HBC team provides follow-up

according to a program based SOP, utilizing a HBC kit provided to these outreach teams. The provider HBC

kit includes ORS, bleach, cotton wool, gloves, soap, calamine lotion, vaseline, gentian violet etc. The team

will provide basic medical assessment and management of symptoms, basic nursing care, nutritional

assessments, domestic support and psychosocial support and make appropriate referrals. HBC teams will

also provide refills of cotrimoxazole, paracetamol, additional clean water kits and additional ITNs to patients

and their families.

All sites focus on the integration of adult care and treatment (ACT) services for all patients regardless of the

source of funding for different components of treatment. TB diagnosis and treatment is provided to all

patients via facility co-location of DOTS centers and/or referral of HIV+ patients into ART from DOTS sites.

ART-eligible patients identified through HCT conducted for all TB patients at DOTS sites will be provided

with ART.

Activity Narrative: Clinical staff at APIN and Harvard sites meet monthly for updates and training. Each site has a clinic

coordinator and senior clinical officer who are responsible for approving drug regimen switching. As clinical

training needs are identified for new sites or new staff at existing sites, through Harvard, APIN provides

training on regimen switching and other relevant topics. In COP09, APIN will make use of the

comprehensive Quality Improvement (QI) Plan incorporated by Harvard using standardized quality

indicators. This includes periodic external site assessments and chart reviews as well as quarterly internal

reviews, based on electronic databases. This QI Plan has been harmonized with HIVQual activities for

participating sites and will continue to be implemented in COP09.

For patients enrolled through the GON National ART Program, we anticipate GON provision of 1st line ARV

drugs and PEPFAR support for ACT services. As patients require alternative or 2nd line drugs, they will

receive PEPFAR provided drugs. GON provision of 1st line drugs allows for additional ACT targets. APIN

will partner with Harvard, Clinton Foundation and Global Fund as appropriate to leverage resources for

providing ARVs to patients. The site investigators and project managers will actively participate in the GON

National ART program. Harmonization of data collection for M&E will be coordinated with USG and GON

efforts. APIN will continue to participate in the USG coordinated Clinical Working Group to address

emerging topics in ARV service provision and to ensure harmonization with other IPs and the GON.

The program will identify, collaborate with and strengthen the capacities of support groups and CBOs, to

deliver palliative care and home based care services. Supported CBOs will provide a range of facility and

HBC services, including prevention for positives, clinical care, prophylaxis and management of OIs,

adherence counseling, psychosocial and spiritual support, and active linkages between hospitals, health

centers, and communities. Through counselors and clinicians at all sites, APIN will provide referrals for TB,

family planning, safe motherhood, and other wrap-around services as appropriate.

APIN will provide training to HCWs and lab scientists working at GON and GF supported sites. APIN will link

up with Harvard in the use of its training lab and linkages with the National Public Health Lab to train them in

ARV lab monitoring. This will serve to increase the quality and sustainability of ACT outside of PEPFAR-

supported sites. APIN will support policy development and implementation of task shifting to improve

access to care and treatment services for PLWHAs. A total of 197 health care and non-health care workers

will be trained in palliative care, including HBC, in line with the National Palliative Care Guidance and the

USG Palliative Care policy.

This funding will support the personnel, clinic and lab services for training of 253 people in ART, monitoring

of 21,350 adults at the end of COP09, which includes 8,200 new adult patients.

EMPHASIS AREAS

This program seeks to increase gender equity in programming through counseling and educational

messages targeted at vulnerable women and girls. Furthermore, through gender sensitive programming and

improved quality services the program will contribute to reduction in stigma and discrimination and address

male norms and behaviors by encouraging men to contribute to care and support in the families.

POPULATIONS BEING TARGETED

The care and treatment components of these activities target HIV-infected adults for clinical monitoring and

ART treatment. The operational elements of these activities (M&E, health personnel training, infrastructural

supports, technical assistance and quality assurance) target public and private program managers, doctors,

nurses, pharmacists and lab workers at PEPFAR sites. The expansion of ART services to secondary health

facilities will increase access to necessary services in poor communities.

CONTRIBUTION TO PROGRAM

ACT activities are consistent with the PEPFAR goal of scaling up capacity to provide ARV drugs, care and

treatment services and lab support to serve more HIV+ people. APIN will continue to support the expansion

of ARV services into more local areas by developing a network of secondary or primary health care clinics

providing ART services that are linked to tertiary health care facilities. These networks will ensure that

facilities are able to develop linkages, which permit patient referral from primary health centers and the

provision of specialty care support. In addition, palliative care services will be provided to 21,350 PLWHA

and 42,700 PABA for a total of 64,050 people served. The program will also contribute to strengthening

human capacity through training of health workers, community workers and PLWHAs and their families.

Additionally, as part of our sustainability building efforts, APIN will receive technical assistance and support

from Harvard to assume program management responsibility for the adult care and treatment Activities.

This will include the implementation of a plan to transition site oversight, management and training over to

APIN. The goal of such efforts is to provide for greater assumption of responsibility for management and

implementation of PEPFAR programming by Nigerian nationals through an indigenous organization.

LINKS TO OTHER ACTIVITIES

This activity is linked to ART drugs, OVC and Pediatric ART Care and Treatment for pediatric care, PMTCT,

TB/HIV to provide ART to patients with TB, Lab to provide ART diagnostics, HCT as an entry point to ART,

and SI (HVSI) will provide the GON with crucial information for use in the evaluation of the National ARV

program and recommended drug regimens. This program is linked to PMTCT services to optimize the

PMTCT by providing ART to eligible pregnant women.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22513

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22513 22513.08 HHS/Centers for AIDS Prevention 9692 9692.08 $100,000

Disease Control & Initiative, LTD

Prevention

Emphasis Areas

Gender

* Addressing male norms and behaviors

* Increasing gender equity in HIV/AIDS programs

Health-related Wraparound Programs

* Malaria (PMI)

* TB

Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Estimated amount of funding that is planned for Food and Nutrition: Commodities $11,780

Economic Strengthening

Education

Water

Estimated amount of funding that is planned for Water $21,178

Table 3.3.08:

Funding for Treatment: Adult Treatment (HTXS): $3,444,198

Several new CDC partners have recently been identified through a competetive funding opportunity

announcement as approved under COP08. Many of these partners are new to the PEPFAR and/or CDC

planning and implementation processes. The amounts awarded differ significantly from the original

proposal amounts submitted by these new partners. The difference now requires the new partners, working

in conjunction with the in-country CDC office and interagency technical working groups, to revise the action

plans for FY08 and FY09. CDC is currently working closely with the new partners to assure their effective

understanding of the PEPFAR planning process and that action plans for FY08 and FY09 COP submissions

are in accordance with funding awards as well as PEPFAR goals and objectives. Detailed narrative

changes will be submitted in the January 2009 reprogramming submission.

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

In COP09, the Harvard School of Public Health (Harvard) plans to move four of the HSPH PEPFAR

supported sites to APIN Ltd. (APIN). The sites include Lagos University Teaching Hospital, Nigerian

Institute of Medical Research, Onikan Women's Hospital, and Mushin General Hospital. This activity

narrative reflects the transfer of targets from Harvard to APIN. The activities will build on the structure and

systems put in place through Harvard. APIN will maintain a strong collaboration with Harvard.

ACTIVITY DESCRIPTION

In COP08 APIN+ provided comprehensive adult care and treatment (ACT) services in 1 site and care and

support at a second site. In COP09, APIN will take over the provision of high quality ARV and basic care

and support services to eligible adult patients at a total of 6 sites; 5 comprehensive ART sites (2, tertiary

and 3 secondary facilities and 1 PHC located in three states of Lagos and Ogun. This will provide ART

services to a total of 13100 adults (8200 new) at the end of the reporting period. Facility-based palliative

care services will be provided to approximately 8250 ART ineligible PLWHA and 13100 ART eligible

PLWHA making a total of 21350 PLWHA clients. People Affected By HIV/AIDS (PABAs) will be reached

through the community and home based care (HBC) of the PLWHA clients.

Patients are identified through HCT services. All HIV-infected individuals are clinically pre-assessed for

eligibility for ARV treatment (ART). Patients who are ineligible for ART are provided with continuous clinical

monitoring and basic care and support services. ART-eligible patients are provided with ART services, in

accordance with a standardized programmatic protocol, which follows the current National ART guidelines.

All HIV+ patients are provided with palliative care services, which are consistent with the Nigerian Palliative

Care Guidelines. A network model of care will be used for service delivery.

ART-ineligible individuals that are enrolled in care will have periodic follow-up to identify changes in

eligibility status. Scheduled physician visits for all are at 3, 6, and 12 months and every 6 months thereafter.

ART patients follow the same clinical visit schedule with more intensified monitoring and pick up drugs

monthly. For all patients, at each visit, clinical exams, hematology, chemistry, viral load, and CD4

enumeration are performed when indicated. All tertiary site labs perform the necessary lab assays.

Secondary and primary sites with limited lab capability send samples to an affiliated tertiary site lab for

analysis. Electronic clinic and lab records provide data for high quality patient care and centrally coordinated

program monitoring. As additional medical needs of patients are identified through clinic visits, they will be

provided with clinical services by clinicians or referred for specialty care as necessary. HIV+ individuals will

be provided with cotrimoxazole prophylaxis according to national guidelines. Diagnostics for common OIs

may include bacterial infections, fungal infections, and protozoal infections. All HIV+ patients will be also

symptomatically screened for TB and confirmed with laboratory and radiological diagnostics as indicated

APIN will support integration of syndromic management of STIs and risk reduction interventions into care.

All PLWHA will be provided with a basic care kit including clean water kits, ITN, and IEC materials on

positive living. Pain assessment will also be conducted by clinicians and HBC providers and analgesics will

be provided. Commodities distributed as a part of the palliative care services are procured centrally through

the APIN Abuja program office and APIN Central Medical Stores in Lagos. Distribution of commodities to

individual sites is coordinated through supply chain mechanisms in place for laboratory test kits and ART

drugs. During COP09, APIN will collaborate with Harvard and SCMS for the procurement and distribution of

specified OI drugs.

Activities will also focus on PWP services. All enrolled into care will receive risk assessment and behavioral

counseling to achieve risk reduction. Condoms will also be provided to prevent STIs and re-infection.

Patients are also encouraged to refer family members for HCT. ART patients are provided ART education &

adherence counseling prior to and during ART provision, which follows the National Curriculum for

Adherence Counseling. ART patients are encouraged to have a treatment support partner to whom he/she

had disclosed status to improve adherence and to optimize care.

APIN will encourage support groups and CBOs to mobilize communities to provide HBC services. Site HBC

activities will be supervised by a hospital team. Facility-based and community-based HBC teams partner to

provide a continuum of HBC services depending on client needs. When ART patients miss scheduled clinic

visits or bed ridden clients are reported by the community HBC team, the site HBC team provides follow-up

according to a program based SOP, utilizing a HBC kit provided to these outreach teams. The provider HBC

kit includes ORS, bleach, cotton wool, gloves, soap, calamine lotion, vaseline, gentian violet etc. The team

will provide basic medical assessment and management of symptoms, basic nursing care, nutritional

assessments, domestic support and psychosocial support and make appropriate referrals. HBC teams will

also provide refills of cotrimoxazole, paracetamol, additional clean water kits and additional ITNs to patients

and their families.

All sites focus on the integration of adult care and treatment (ACT) services for all patients regardless of the

source of funding for different components of treatment. TB diagnosis and treatment is provided to all

patients via facility co-location of DOTS centers and/or referral of HIV+ patients into ART from DOTS sites.

ART-eligible patients identified through HCT conducted for all TB patients at DOTS sites will be provided

with ART.

Activity Narrative: Clinical staff at APIN and Harvard sites meet monthly for updates and training. Each site has a clinic

coordinator and senior clinical officer who are responsible for approving drug regimen switching. As clinical

training needs are identified for new sites or new staff at existing sites, through Harvard, APIN provides

training on regimen switching and other relevant topics. In COP09, APIN will make use of the

comprehensive Quality Improvement (QI) Plan incorporated by Harvard using standardized quality

indicators. This includes periodic external site assessments and chart reviews as well as quarterly internal

reviews, based on electronic databases. This QI Plan has been harmonized with HIVQual activities for

participating sites and will continue to be implemented in COP09.

For patients enrolled through the GON National ART Program, we anticipate GON provision of 1st line ARV

drugs and PEPFAR support for ACT services. As patients require alternative or 2nd line drugs, they will

receive PEPFAR provided drugs. GON provision of 1st line drugs allows for additional ACT targets. APIN

will partner with Harvard, Clinton Foundation and Global Fund as appropriate to leverage resources for

providing ARVs to patients. The site investigators and project managers will actively participate in the GON

National ART program. Harmonization of data collection for M&E will be coordinated with USG and GON

efforts. APIN will continue to participate in the USG coordinated Clinical Working Group to address

emerging topics in ARV service provision and to ensure harmonization with other IPs and the GON.

The program will identify, collaborate with and strengthen the capacities of support groups and CBOs, to

deliver palliative care and home based care services. Supported CBOs will provide a range of facility and

HBC services, including prevention for positives, clinical care, prophylaxis and management of OIs,

adherence counseling, psychosocial and spiritual support, and active linkages between hospitals, health

centers, and communities. Through counselors and clinicians at all sites, APIN will provide referrals for TB,

family planning, safe motherhood, and other wrap-around services as appropriate.

APIN will provide training to HCWs and lab scientists working at GON and GF supported sites. APIN will link

up with Harvard in the use of its training lab and linkages with the National Public Health Lab to train them in

ARV lab monitoring. This will serve to increase the quality and sustainability of ACT outside of PEPFAR-

supported sites. APIN will support policy development and implementation of task shifting to improve

access to care and treatment services for PLWHAs. A total of 197 health care and non-health care workers

will be trained in palliative care, including HBC, in line with the National Palliative Care Guidance and the

USG Palliative Care policy.

This funding will support the personnel, clinic and lab services for training of 253 people in ART, monitoring

of 21,350 adults at the end of COP09, which includes 8,200 new adult patients.

EMPHASIS AREAS

This program seeks to increase gender equity in programming through counseling and educational

messages targeted at vulnerable women and girls. Furthermore, through gender sensitive programming and

improved quality services the program will contribute to reduction in stigma and discrimination and address

male norms and behaviors by encouraging men to contribute to care and support in the families.

POPULATIONS BEING TARGETED

The care and treatment components of these activities target HIV-infected adults for clinical monitoring and

ART treatment. The operational elements of these activities (M&E, health personnel training, infrastructural

supports, technical assistance and quality assurance) target public and private program managers, doctors,

nurses, pharmacists and lab workers at PEPFAR sites. The expansion of ART services to secondary health

facilities will increase access to necessary services in poor communities.

CONTRIBUTION TO PROGRAM

ACT activities are consistent with the PEPFAR goal of scaling up capacity to provide ARV drugs, care and

treatment services and lab support to serve more HIV+ people. APIN will continue to support the expansion

of ARV services into more local areas by developing a network of secondary or primary health care clinics

providing ART services that are linked to tertiary health care facilities. These networks will ensure that

facilities are able to develop linkages, which permit patient referral from primary health centers and the

provision of specialty care support. In addition, palliative care services will be provided to 21,350 PLWHA

and 42,700 PABA for a total of 64,050 people served. The program will also contribute to strengthening

human capacity through training of health workers, community workers and PLWHAs and their families.

Additionally, as part of our sustainability building efforts, APIN will receive technical assistance and support

from Harvard to assume program management responsibility for the adult care and treatment Activities.

This will include the implementation of a plan to transition site oversight, management and training over to

APIN. The goal of such efforts is to provide for greater assumption of responsibility for management and

implementation of PEPFAR programming by Nigerian nationals through an indigenous organization.

LINKS TO OTHER ACTIVITIES

This activity is linked to ART drugs, OVC and Pediatric ART Care and Treatment for pediatric care, PMTCT,

TB/HIV to provide ART to patients with TB, Lab to provide ART diagnostics, HCT as an entry point to ART,

and SI (HVSI) will provide the GON with crucial information for use in the evaluation of the National ARV

program and recommended drug regimens. This program is linked to PMTCT services to optimize the

PMTCT by providing ART to eligible pregnant women.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22509

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22509 22509.08 HHS/Centers for AIDS Prevention 9692 9692.08 $290,000

Disease Control & Initiative, LTD

Prevention

Emphasis Areas

Gender

* Addressing male norms and behaviors

* Increasing gender equity in HIV/AIDS programs

Health-related Wraparound Programs

* Malaria (PMI)

* TB

Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Estimated amount of funding that is planned for Food and Nutrition: Commodities $5,890

Economic Strengthening

Education

Water

Estimated amount of funding that is planned for Water $21,178

Table 3.3.09:

Funding for Care: Pediatric Care and Support (PDCS): $180,411

Several new CDC partners have recently been identified through a competetive funding opportunity

announcement as approved under COP08. Many of these partners are new to the PEPFAR and/or CDC

planning and implementation processes. The amounts awarded differ significantly from the original

proposal amounts submitted by these new partners. The difference now requires the new partners, working

in conjunction with the in-country CDC office and interagency technical working groups, to revise the action

plans for FY08 and FY09. CDC is currently working closely with the new partners to assure their effective

understanding of the PEPFAR planning process and that action plans for FY08 and FY09 COP submissions

are in accordance with funding awards as well as PEPFAR goals and objectives. Detailed narrative

changes will be submitted in the January 2009 reprogramming submission.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22515

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22515 22515.08 HHS/Centers for AIDS Prevention 9692 9692.08 $50,000

Disease Control & Initiative, LTD

Prevention

Emphasis Areas

Gender

* Addressing male norms and behaviors

* Increasing gender equity in HIV/AIDS programs

Health-related Wraparound Programs

* Child Survival Activities

* Malaria (PMI)

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $20,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.10:

Funding for Treatment: Pediatric Treatment (PDTX): $370,470

If continuing, paste your COP08 narrative here and put one of the following at the beginning of your

narrative:

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

In COP09, the Harvard School of Public Health (Harvard) plans to move over four of its PEPFAR supported

sites to APIN Ltd. (APIN). The sites include Lagos University Teaching Hospital, Nigerian Institute of

Medical Research, Onikan Women's Hospital, and Mushin General Hospital. The activity narrative reflects

the transfer of targets from Harvard to APIN. The activities will build on the structure and systems put in

place through Harvard. APIN will maintain a strong collaboration with Harvard University.

ACTIVITY DESCRIPTION

In COP08 APIN+ provided comprehensive pediatric care and treatment (PCT) services in 1 site. In COP09,

APIN will take over provision of high quality ARV and basic care and support services to eligible pediatric

patients at a total of 5 sites; 5 comprehensive ART sites (2 tertiary and 3 secondary facilities) located in two

states of Lagos and Ogun. This will provide ART services to a total of 1050 children (700 new) at the end of

the reporting period. Facility-based palliative care services will be provided to approximately 413 ART

ineligible children and 1050 ART eligible children for a total of 1463 pediatric PLWHA clients. People

Affected By HIV/AIDS (PABAs), including caregivers of pediatric PLWHA, will be reached through the

community and home based care (HBC) services; therefore, it is expected that a total of 4389 individuals

will access services (1463 pediatric PLWHA and 2926 PABA).

Patients are identified through PMTCT and HCT services including facility based, mobile, and family

centered strategies. Early infant diagnosis (EID) is performed for children =18 months utilizing DNA PCR at

2 tertiary level sites, Secondary and primary sites send samples to an affiliated tertiary site lab for analysis.

All HIV+ children are clinically pre-assessed for eligibility for ARV treatment (ART). Patients who are

ineligible for ART, are provided with continuous clinical monitoring and basic care and support services.

ART-eligible patients are provided with ART services, in accordance with a standardized programmatic

protocol, which follows the 2005 revised National ART guidelines. All HIV+ patients are provided with

palliative care services, which are consistent with the Nigerian Palliative Care Guidelines.

ART-ineligible children that are enrolled in care will have periodic follow-up to identify changes in eligibility

status. Scheduled physician visits for all are at 3, 6, and 12 months and every 6 months thereafter. ART

patients follow the same clinical visit schedule with more intensified monitoring and pick up drugs monthly.

For all patients, at each visit, clinical and lab exams. All tertiary site labs perform the necessary lab assays.

Secondary and primary sites with limited lab capability send samples to an affiliated tertiary site. Electronic

clinic and lab records provide data for high quality patient care and centrally coordinated program

monitoring. As additional medical needs are identified through clinic visits, patients will be provided with

clinical services by clinicians or referred for specialty care as necessary. HIV+ children will be provided with

a package of preventative care services, including cotrimoxazole prophylaxis according to national

guidelines and referrals to the National Vaccination program for childhood vaccinations. Diagnostics for

common OIs may include: Candida albicans, protozoal infections, and gastrointestinal parasites. All HIV+

children will be also symptomatically screened for TB and confirmed with TST, laboratory and radiological

diagnostics as indicated. HIV+ children are also provided with nutritional counseling and supplements,

including multivitamins, growth monitoring, and care for childhood illnesses. All HIV+ children and their

caregivers will be provided with a basic care package including clean water kits, ITN, and IEC materials.

Pain management assessments will also be conducted by clinicians and HBC providers and analgesics will

be provided. All HIV+ children are linked into the system of OVC services in order to ensure a continuum of

care.

Commodities distributed as a part of the palliative care services are procured centrally through the APIN

Abuja program office and Central Medical Stores in Lagos. Distribution of commodities to individual sites is

coordinated through supply chain mechanisms in place for laboratory test kits and ART drugs. During

COP09, APIN will collaborate with Harvard, SCMS for the procurement and distribution of specified

pediatric OI drugs.

All enrolled into care will receive risk assessment and behavioral counseling to achieve risk reduction.

Caregivers for HIV+ children are provided ART EAC prior to and during ART provision, which follows the

National Curriculum for Adherence Counseling. ART EAC is reinforced with PLWHA support groups at each

site, which serve all HIV+ patients and their families. APIN will partner with support groups and CBOs to

mobilize communities provide HBC activities.

Facility-based and community-based HBC teams partner to provide a continuum of HBC services

depending on client needs. When ART patients miss scheduled clinic visits or bed ridden clients are

reported by the community HBC team, the site HBC team provides follow-up according to a program based

SOP, utilizing a HBC kit provided to these outreach teams. The HBC includes ORS, bleach, cotton wool,

gloves, soap, calamine lotion, vaseline, gentian violet. The team will provide basic medical assessments of

signs and symptoms, basic nursing care, nutritional assessments and psychosocial support and make

appropriate referrals. HBC teams will also provide refills of cotrimoxazole, paracetamol, additional clean

water kits and additional ITNs to patients and their families. Site HBC activities will be supervised by a

hospital team.

All sites focus on the integration of PCT services for all patients regardless of the source of funding for

different components of treatment. At each site support is provided for the management of electronic data

and patient medical records for use in the provision of clinical care. TB diagnosis and treatment is provided

to all patients via facility co-location of DOTS centers and/or referral of HIV+ patients into ART from DOTS

sites. ART-eligible patients identified through HCT conducted for all TB patients at DOTS sites will be

provided with ART.

Clinical staff at APIN and Harvard sites meets monthly for updates and training. Each site has a clinic

coordinator and senior clinical officer who is responsible approving drug regimen switching. As clinical

training needs are identified for new sites or new staff at existing sites, through APIN, Harvard provides

training on regimen switching and other relevant topics. During COP09 APIN will scale up the Harvard

initiated QA/QI activities to all supported sites using standardized quality indicators. This will include

Activity Narrative: periodic external site assessments and chart reviews as well as quarterly internal reviews, based on

electronic databases.

For pediatric patients enrolled through the GON National ART Program, we anticipate GON provision of 1st

line ARV drugs and PEPFAR support for PCT services. As patients require alternative or 2nd line drugs,

they will receive PEPFAR provided drugs. GON provision of 1st line drugs allows for additional PCT targets.

APIN will partner with Harvard, SCMS, Clinton Foundation as appropriate to leverage resources for

providing ARVs to patients. The site investigators and project managers will actively participate in the GON

National ART program. Harmonization of data collection for M&E will be coordinated with USG and GON

efforts. APIN will provide technical assistance and training expertise to the National ART program's training

program in 2009. APIN will continue to participate in the USG coordinated Clinical Working Group to

address emerging topics in ARV service provision for children and to ensure harmonization with other IPs

and the GON.

The program will identify and strengthen the capacities of support groups and CBOs to deliver pediatric

palliative care, OVC services and HBC services. Through counselors and clinicians at all sites, APIN will

provide referrals for TB, wraparound services and child survival programs as appropriate.

APIN will support training of site-based HCWs and lab scientists working at GON and GF supported sites in

EID techniques. A total of 103 health care and non-health care workers will be trained in PCT services in

line with the National Pediatric ART Guidelines and the National Training Curriculum.

This funding will support the personnel, clinic and lab services for training of 106 people, monitoring of 1463

pediatric patients at the end of COP09, which includes 700 new pediatric patients. A total of 1050 patients

will be provided with pediatric ART services.

EMPHASIS AREAS

Through the provision of ITNs, provision of malaria smears, TB screening and linkages to TB DOTS

programs, we also provide focus on malaria and TB wrap-arounds. We will also provide emphasis on child

survival wrap-around programming, through the provision of clean water kits, growth monitoring, nutritional

supports, treatment of OIs and other illnesses, and counseling for caregivers on hygiene and nutrition for

HIV-infected children.

POPULATIONS BEING TARGETED

The care and treatment components of these activities target HIV+ children for clinical monitoring and ART.

The operational elements of these activities (M&E, health personnel training, infrastructural supports,

technical assistance and quality assurance) target public and private program managers, doctors, nurses,

pharmacists and lab workers at PEPFAR sites. The expansion of PCT to secondary health facilities will

increase access to necessary services in poor communities.

CONTRIBUTION TO PROGRAM

PCT activities are consistent with the PEPFAR goal of scaling up capacity to provide ARV drugs, care and

treatment services and lab support to serve more HIV+ children. APIN will continue to support the

expansion of PCT services into more local areas by developing a network model. These networks will

ensure that facilities are able to develop linkages, which permit patient referral from primary health centers

and the provision of specialty care support. A tiered structure for ARV provision and monitoring established

through Harvard provides a model for additional expansion efforts in COP09 in order to meet PEPFAR

treatment goals. In addition, pediatric palliative care services will be provided to 1463 HIV+ children and

2926 PABA for a total of 4389 people served. The program will also contribute to strengthening human

capacity through training of health workers, community workers and HIV+ children and their families.

Additionally, as part of our sustainability building efforts, APIN will receive technical assistance and support

from Harvard to assume program management responsibility for the PCT Activities. This will include the

implementation of a plan to transition site oversight, management and training over to APIN. The goal of

such efforts is to provide for greater assumption of responsibility for management and implementation of

PEPFAR programming by Nigerian nationals through an indigenous organization.

LINKS TO OTHER ACTIVITIES

This activity is linked to ART drugs (HTXD), OVC (HKID) and Adult ART Care and Treatment (HTXS) for

pediatric care, PMTCT (MTCT), TB/HIV (HVTB) to provide ART to patients with TB, Lab (HLAB) to provide

ART diagnostics, HCT (HVCT) as an entry point to ART, and SI (HVSI) will provide the GON with crucial

information for use in the evaluation of the National ARV program and recommended drug regimens. This

program is linked to PMTCT services to optimize the PMTCT by providing ART to eligible pregnant women.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22509

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22509 22509.08 HHS/Centers for AIDS Prevention 9692 9692.08 $290,000

Disease Control & Initiative, LTD

Prevention

Emphasis Areas

Gender

* Addressing male norms and behaviors

* Increasing gender equity in HIV/AIDS programs

Health-related Wraparound Programs

* Child Survival Activities

* Malaria (PMI)

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $20,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.11:

Funding for Care: TB/HIV (HVTB): $502,905

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

In COP09, the Harvard School of Public Health (Harvard) plans to move over 4 of its PEPFAR supported

sites to APIN Ltd. (APIN). The sites include Lagos University Teaching Hospital, Nigerian Institute of

Medical Research, Onikan Women's Hospital, and Mushin General Hospital. The activity narrative reflects

the transfer of targets from Harvard to APIN. The activities will build on the structure and systems put in

place through Harvard. APIN will maintain a strong collaboration with Harvard University.

ACTIVITY DESCRIPTION:

In COP09, APIN sites will identify HIV infected patients through PMTCT, HCT centers and ART centers and

hospitals and outreaches. These sites constitute a network of delivery points in 3 states (Lagos, Ogun and

Oyo) and include 2 tertiary hospitals, 3 secondary hospitals, 1 PHC and 43 DOTS centers. In COP9, APIN

plans to execute a universal coverage strategy in Oyo state, by providing support for TB-HIV services in all

state government supported DOTS centers throughout the state. This is an essential step toward universal

access to TB/HIV services, and will focus on developing programming at the secondary and primary level.

All HIV-infected individuals are clinically pre-assessed for eligibility for ART treatment; it is expected that

700 HIV positive clients will be screened for TB in COP09. TB screening by sputum examination is

conducted according to national guidelines. The13,100 new and maintenance patients already on ART will

also be monitored for TB. All 852 HIV infected women from our 5 treatment sites will be assessed for ART

eligibility and screened for TB. The TB clinics at 2 of our sites are National TB centers offering the

government DOTS program. At all of our associated DOTS clinics, we will implement HCT for 9,700 clients

presenting to the DOTS center. In all, it is expected that 2,825 TB/HIV co-infected patients will be identified

and will receive treatment for TB and be linked to Harvard and APIN ART clinics for evaluation of eligibility

for ART and provision of care and treatment.

The National Tuberculosis Reference Laboratory (NTRL) will provide an important resource to APIN sites in

strengthening their capacity for TB diagnosis and cross-training of health care workers in TB/HIV. The

NTRL will provide screening for MDR-TB. TB services provided at these clinics will be integrated with ART

services and HCT in order to promote the development of a comprehensive system of care for individuals

with HIV/TB co-infection. This will be part of the 148 health care workers in both HIV and TB clinical and

laboratory settings to be trained in COP09. APIN TB/HIV program officers and facility staff will be provided

with formal TB/HIV training to enhance their productivity, including retraining on x-ray diagnostic skills and

co-management of TB/HIV for clinicians; and retraining on good sputum specimen collection and laboratory

AFB sputum smear diagnosis for laboratory technicians. There will also be training on TB infection control

and HCT. A dedicated TB program officer provides TB expertise to all Harvard and APIN sites and is

responsible for training efforts and reporting of TB patients to the NTPLCP.

APIN will implement the global 3 "I"s strategy in COP09 through intensive TB/HIV case finding amongst HIV

positive patients, TB infection control in all ART sites and INH Prophylaxis Therapy (IPT). APIN will prevent

nosocomial transmission of TB to HIV+ patients through such measures and principles such as basic

hygiene, proper sputum disposal, and good cross ventilation at clinics. Facility co-location of TB/HIV

services is preferred to clinic co-location. The national guidelines on TB infection control on co-located sites

will be implemented in all sites. Patient and staff education on infection control measures will be routinely

carried out to ensure program success. APIN will upgrade facilities as needed through infrastructure support

such as basic renovations and space modification to ensure effective infection control, upgrading equipment

and procuring supplies and consumables (e.g. sputum containers).

To date, more than 30% of APIN+ clinic attendees present with pulmonary tuberculosis. Depending on

clinical status, many patients will be treated for TB prior to receiving ART, following the NTBLCP Guidelines.

Concurrent ART and TB treatment follows the National guidelines. All co-infected patients will receive co-

trimoxazole according to national guidelines. IPT will be provided through the ART clinics following the

global 3 "I"s principle and the national guidelines. The TB DOTS sites will be supported to provide holistic

patient care according to National and IMAI guidelines. Cross-referrals and linkages between TB and HIV

programs will be strengthened.

APIN home-based care providers will track family members and contacts of TB patients who are at risk of

developing TB and get them screened for TB, as well as HIV. This will result in higher TB case detection

and increased HCT uptake. They will also provide adherence support for TB and ARV drug treatment. Site

support groups will be involved in community mobilization and will include TB education in their outreach

messages.

At NIMR, APIN will provide technical assistance in the implementation of MDR-TB and XDR-TB surveillance

activities in Nigeria. TB diagnostic capacity will include culture, PCR, and sequencing for resistance testing.

In COP09, APIN will work with 43 DOTS centers at secondary sites in all LGAs of Oyo state. These DOTS

centers will be linked with two tertiary care sites for specialty care. At each DOTS center, we will provide

HCT for TB patients and support the provision of broad HIV/TB services for all patients served, including

referrals to ART centers for patients identified as HIV infected. To ensure continuous availability of drugs

and commodities in supported sites, APIN will partner with Harvard and other USG PEPFAR team members

to strengthen logistics management within the states where it works.

EMPHASIS AREAS:

Emphasis areas include gender and health-related wrap around activities. This activity will increase gender

equity by focusing on strategies which seek to reach an equitable number of co-infected men and women.

Furthermore, it seeks to provide additional focus on support for pregnant women who have TB/HIV.

Through data collection and patient surveillance from this activity, APIN will be able to show the breakdown

of men and women who are accessing TB diagnostics and treatment services. Outreach activities and

patient counseling also seek to address stigma and discrimination and increase access to information,

education and TB diagnosis and treatment for women and girls with HIV. In addition, APIN will focus on

providing linkages to wrap around services for TB, which will focus on MDR-TB detection and treatment.

Focus will also be places on intensified case detection through developing linkages with community based

Activity Narrative: health care facilities to build capacity for TB screening.

POPULATIONS BEING TARGETED:

This activity targets adults and children with HIV and TB co-infection by providing a mechanism for critically

important TB diagnosis and treatment both prior to the initiation of ART and also during the course of ART

therapy. Newly enrolling ART patients will be prescreened for TB in COP09 and TB that develops in

patients who are currently on ART therapy will be diagnosed and treated. All HIV infected pregnant women

participating in APIN PMTCT programs will also be eligible for TB diagnosis and treatment under this

program. TB patients at DOTS clinics will be screened for HIV. Their family members and contacts will also

be targeted for TB and HIV screening.

CONTRIBUTION TO OVERALL PROGRAM:

The provision of TB diagnostics and treatment within participating ART facilities is consistent with the

PEPFAR goal of ensuring that all facilities offering ART develop the ability to diagnose TB and provide

nationally accepted DOTS sites within their facility. There will a deliberate attempt to locate HCT in DOTS

centers so as to increase detection of co-infected TB/HIV patients. At these facilities, APIN estimates that it

will provide clinical treatment for TB to 2825 patients with HIV/TB co-infection either prior to or during their

ART therapy, thus contributing significantly to the 2009 PEPFAR goals. At all APIN sites referral to TB

DOTS sites that are co-located will be provided. The provision of TB diagnosis and treatment, infrastructure

building and health care personnel training under this program will work towards building and maintaining

Nigerian National tuberculosis treatment capacity.

Additionally, as part of the sustainability building efforts, APIN will receive technical assistance and support

from Harvard to assume program management responsibility for the TB/HIV Activities. This will include the

implementation of a plan to transition site oversight, management and training over to APIN. The goal of

such efforts is to provide for greater assumption of responsibility for management and implementation of

PEPFAR programming by Nigerian nationals through an indigenous organization.

LINKS TO OTHER ACTIVITIES:

This activity also relates to activities in HCT, Adult Care and Treatment, Pediatric Care and Treatment,

PMTCT and OVC. Through this activity linkages between participating treatment sites and the National

Tuberculosis Reference Laboratory will be provided. Additionally, linkages to potential patient populations

through outreach initiatives, HCT activities, and ART services will improve utilization of care opportunities

created through PEPFAR funding. This activity is linked to care and support and ART services because TB

diagnosis and treatment are provided as a part of patient palliative care and support at sites which also

provide ART. A high TB co-infection rate has a major impact on ART management.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22514

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22514 22514.08 HHS/Centers for AIDS Prevention 9692 9692.08 $510,000

Disease Control & Initiative, LTD

Prevention

Emphasis Areas

Gender

* Increasing gender equity in HIV/AIDS programs

Health-related Wraparound Programs

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $60,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.12:

Funding for Care: Orphans and Vulnerable Children (HKID): $192,476

Several new CDC partners have recently been identified through a competetive funding opportunity

announcement as approved under COP08. Many of these partners are new to the PEPFAR and/or CDC

planning and implementation processes. The amounts awarded differ significantly from the original

proposal amounts submitted by these new partners. The difference now requires the new partners, working

in conjunction with the in-country CDC office and interagency technical working groups, to revise the action

plans for FY08 and FY09. CDC is currently working closely with the new partners to assure their effective

understanding of the PEPFAR planning process and that action plans for FY08 and FY09 COP submissions

are in accordance with funding awards as well as PEPFAR goals and objectives. Detailed narrative

changes will be submitted in the January 2009 reprogramming submission.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22515

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22515 22515.08 HHS/Centers for AIDS Prevention 9692 9692.08 $50,000

Disease Control & Initiative, LTD

Prevention

Table 3.3.13:

Funding for Testing: HIV Testing and Counseling (HVCT): $45,102

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

In COP09, the Harvard School of Public Health (Harvard) plans to move over four of its PEPFAR-supported

sites to APIN Ltd. (APIN) an indigenous NGO. The sites include Lagos University Teaching Hospital,

Nigerian Institute of Medical Research, Onikan Health Center, and Mushin General Hospital. The activity

narrative reflects the transfer of targets from Harvard to APIN. The activities will build on the structure and

systems put in place through Harvard. APIN will maintain a strong collaboration with Harvard.

ACTIVITY DESCRIPTION:

In COP09, APIN plans to support provision of comprehensive HIV counseling and testing (HCT) services to

at-risk individuals, delivered through 49 service outlets (5 comprehensive sites, 1 Primary Health Care

(PHC) and 43 Directly Observed Treatment (DOT) centers) in 3 states (Lagos, Ogun and Oyo). When

including TB sites, 10,200 individuals (3,774 males and 6,426 females) will receive HCT and receive their

results; when excluding TB sites, the number that will be counseled, tested and receive results is 4,500

(1,665 males and 2,835 females). Targeted populations include most-at-risk populations (MARPs), clients

presenting to the health care facilities, blood donors, and family members of PLWHA. Provider-initiated HIV

testing is utilized as an additional strategy to reach clients at the health care facilities. The sites will include

DOT centers in at least one health facility in every local government area (LGA) in Oyo State. In COP09 the

APIN HCT site and community level activities will stress: (1) providing technical assistance, particularly in

identifying most at risk persons in need of HCT, and (2) working with sites to identify and obtain additional

resources (from the GON, other donors, Global Fund, etc.) to provide commodities and increase uptake of

HCT services.

In COP08, APIN supported provision of comprehensive HIV counseling and testing (HCT) services to at-risk

individuals, delivered through 45 service outlets (1 comprehensive site, 1 PHC and 43 DOT centers) in 3

states (Lagos, Ogun and Oyo).

Individuals identified as positive at APIN sites will be referred to PMTCT and ART clinics for treatment and

palliative care services. Prevention for HIV positive individuals will be incorporated into HCT activities

including promotion of HCT for family members and sex partners, counseling for discordant couples,

counseling on healthy lifestyles and positive living, prevention messages and Information, Education &

Communication (IEC) materials on disclosure. APIN sites use family counseling sessions and "love letter"

strategies to encourage partners of HIV-infected patients to access HCT so that couples receive HIV

counseling and testing together. Counselor training will include couple HIV counseling and testing (CHCT)

to strengthen this program. Pediatric patients that are identified at testing points of service will be enrolled

into the APIN supported OVC program and ART as necessary. HCT will also be offered to patients

receiving TB services at each of the APIN-supported sites throughout TB/HIV program activities. HCT is

offered to blood donors as per Blood Safety activities. Patients identified as HIV-infected are provided with

referrals to ART and palliative care services.

APIN will use the National "Heart to Heart" logo at supported HCT sites so as to reflect the integration within

the national program. At all HCT outlets, patients are provided with IEC materials on HIV prevention and

referrals for ART services and palliative care as appropriate. The materials will address HIV prevention

using the "ABC" model, providing information about healthy behaviors, safer sexual practices, STI

prevention, PMTCT, and condom usage. The sites will also provide HIV testing as well as pre- and post-test

counseling and condom distribution.

HCT services are also provided in community settings in conjunction with projects in Lagos state that serve

specific MARPs including: outpatient STI patients, bar workers, and sex workers. Mobile HCT services

coordinated through PHC-Iru will be used to reach these populations. Activities targeting these populations

are linked with APIN sites to provide referral linkages to PMTCT, Palliative HIV/TB and ART services

depending on eligibility for ART.

Condoms will be made available at all HCT sites in conjunction with the delivery of ABC messages. The

Society for Family Health (SFH) will supply condoms. Training of 20 individuals in counseling and testing

will use the new National serial testing algorithm and will educate trainees on appropriate counseling

messages specific to the different high risk groups with which they work. Refresher training will be provided

to a subset of the target trained during the year, particularly after final revision of the National training

curriculum. HIV testing is performed with rapid test assays and same day results are given. Following HIV

diagnosis with the National testing algorithm, immunoblot confirmation will be provided during assessment

for ART in line with the national algorithm. This is done by HIV laboratories at APIN-supported

comprehensive ART treatment centers.

To meet up with the increase demand for services, non-laboratorians, including nurses, counselors and lay

counselors will be trained to provide counseling and testing services at one visit using finger prick. These

will be supervised by laboratory scientists and the quality of testing would be ensured by proficiency testing

and quarterly supervisory visits. The University College Hospital (UCH) Virology lab supported through

Harvard will establish and coordinate a regular QA/QC program to insure that HIV serologic testing at APIN-

supported HCT centers meets national and international standards. This lab will also ensure coordination of

HIV testing standard operating procedures (SOPs) and provide regular training for new lab personnel. The

USG team will be providing APIN with rapid test kits that will be managed by the pharmacy logistics team in

Lagos and stored and distributed from the APIN central medical stores warehouse. APIN in collaboration

with Harvard will continue to harmonize the logistics process with GON Logistics Management Information

System (LMIS) and Inventory Control System (ICS) activities.

EMPHASIS AREAS:

These activities will also address gender equity issues by providing equitable access to HCT services for

men and women. In some cases, the activities seek to target men who may be at high risk for HIV in order

to provide a mechanism for HCT as a means of prevention and access to services for their sexual partners.

Male targeted counseling seeks to address male norms and behaviors in order to encourage safer sexual

practices. Counseling also seeks to address sexual norms and issues of HIV related stigma and

Activity Narrative: discrimination.

TARGET POPULATIONS:

These activities target adults for HIV counseling and testing, particularly those from MARPs, as described

above. Targeting these populations is important to encourage utilization of HCT services and provide ART

for eligible HIV-infected individuals. Counseling provided through these activities also seeks to target

PLWHA who are newly diagnosed by encouraging them to bring their partners and other family members in

for HCT. In addition, target populations include orphans and vulnerable children.

CONTRIBUTION TO OVERALL PROGRAM AREA:

APIN HCT activities are consistent with the PEPFAR 2009 goals for Nigeria, which aim to increase uptake

of HCT by supporting HCT centers, which are linked to treatment and care services, to target MARPs. By

continuing to support and build the capacity of HCT centers and provide linkages to treatment and care

centers, these activities will be able to meet the increasing utilization of these services, expected to result

from HCT outreach initiatives identifying infected individuals. The network of HCT centers linked to HIV

services and care will provide a sustainable network for infected and affected individuals in APIN

catchments areas.

Additionally, as part of the sustainability building efforts, APIN will receive technical assistance and support

from Harvard to assume program management responsibility for these HCT activities. This will include the

implementation of a plan to transition site oversight, management and training over to APIN. The goal of

such efforts is to provide for greater assumption of responsibility for management and implementation of

PEPFAR programming by Nigerian nationals through an indigenous organization.

LINKS TO OTHER ACTIVITIES:

This activity also relates to activities in Adult Care and Treatment, Pediatric Care and Treatment, Sexual

Prevention, TB/HIV, and OVC. APIN will link with the Harvard's network of community, research-based, and

tertiary care institutions, which should provide sustainable and high quality HIV and related services to the

communities served. Furthermore, both primary and satellite APIN sites are linked in order to provide

laboratory and specialty care support, as related to the HCT activities.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22516

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22516 22516.08 HHS/Centers for AIDS Prevention 9692 9692.08 $140,000

Disease Control & Initiative, LTD

Prevention

Emphasis Areas

Gender

* Addressing male norms and behaviors

* Increasing gender equity in HIV/AIDS programs

Health-related Wraparound Programs

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $1,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.14:

Funding for Treatment: ARV Drugs (HTXD): $3,455,563

If continuing, paste your COP08 narrative here and put one of the following at the beginning of your

narrative:

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

In COP09, the Harvard School of Public Health (Harvard) plans to move over four of its PEPFAR supported

sites to AIDS Prevention Initiative Nigeria, Limited. (APIN Ltd). The sites include Lagos University Teaching

Hospital, Nigerian Institute of Medical Research, Onikan Women's Hospital, and Mushin General Hospital.

The activity narrative reflects the transfer of targets from Harvard to APIN Ltd. APIN Ltd. will support the

management of the Central Medical Store (CMS) for both Harvard and APIN Ltd. supported sites. The

activities will build on the structure and systems put in place through Harvard. APIN Ltd. will maintain a

strong collaboration with Harvard.

ACTIVITY DESCRIPTION:

Through these activities, APIN Ltd. will provide antiretroviral (ARV) drugs to 13,100 adult and 1,050

pediatric patients at six APIN Ltd. sites in three states (Lagos, Ogun and Oyo), all of which are

comprehensive antiretroviral treatment (ART) sites serving pregnant women, adults and children. Two of

the six sites are also supported by the Government Of Nigeria (GON) with close to 14% of patients

receiving ARV drugs from GON. At all sites APIN Ltd. will provide prevention of mother to child treatment

(PMTCT) drugs including all prophylaxis options and triple drug ART regimens for eligible pregnant women

consistent with the national PMTCT and ART guidelines. Thus, a total of six APIN Ltd. sites will be providing

ARV drugs through ART or PMTCT services.

All drug orders are based on projections of patient numbers as determined by annual forecasts conducted

in August 2008 in conjunction with the Harvard/APIN Ltd country team, SCMS and USG Logistics Technical

Working group. The determining factors were rate of patient enrollment, weight class of patients affecting

drug dosage, gender, rates of toxicity, and rates of failure. Our rates of drug ordering and estimation of

buffer stock needs have been informed by our experience with lengthy and variable order to delivery times,

global shortages, splitting of most orders, delays in National Agency for Food, Drug Administration and

Control (NAFDAC) registration and lengthy clearance of drugs in country. As a result, our drug forecasts

and orders had been adjusted to accommodate with an increase in buffer stocks. This year, we have buffer

stocks for approximately 3-5 months for all of the requisite PMTCT, first and second line ARV drugs. Based

on patient baseline data, fixed dose combinations (FDC) of CBV+EFV/NVP will be used for first line

regimen; patients with anemia or Hepatitis B/C will be placed on TDF+FTC+NVP/EFV. Other first line

alternative regimens and second line regimens will be dictated based on individual patient data or history.

FDC and generic drugs will be used preferentially. Currently 7% of patients on ART are on second-line and

93% on first line regimens. APIN Ltd. will receive technical assistance from Harvard and Northwestern

University for drug ordering and supply chain management. Drug usage updates are provided to all APIN

Ltd. and Harvard investigators by email on a monthly basis.

APIN Ltd. will purchase the drugs in accordance with USG, FDA and National Agency for Food and Drug

Administration and Control (NAFDAC) regulations as well as with the 2007 National Standard Treatment

Guidelines. In COP09, APIN Ltd. will continue to collaborate with the Clinton Foundation for the receipt of

second line adult and all the pediatric drugs. APIN LTD. will also work closely with the Government of

Nigeria to leverage resources for the sites supported by both PEPFAR and GON. All purchases of Truvada

(TDF/FTC) and ZDV-3TC-NVP Fixed Dose will be procured via pooled procurement mechanism by SCMS

in line with OGAC's recommendation. The rest of the drugs will be purchased via IDA and other

procurement mechanisms. Drugs will be shipped to APIN Ltd.'s Central Medical Stores (CMS) in Lagos,

from where they will be distributed to sites in accordance with the internal supply chain management

system, which is collaboratively managed by APIN Ltd. and Harvard. APIN Ltd. maintains a subcontract with

Fed-Ex to provide monthly distribution to all site pharmacies. An electronic bin card system is utilized to

track and monitor drug stores and the distribution..

APIN Ltd. has developed standard operating procedures (SOPs) for supply chain management, drug usage,

drug regimen tracking, drug distribution, warehouse storage, waste management and individual pharmacy

site management. These SOPs are also used for procurement and distribution of opportunistic infection (OI)

drugs and certain lab supplies and test kits.

Capacity building and training for individual site pharmacies is ongoing to support pharmacy management

and implementation of the National ART Program. APIN Ltd. and Harvard are participating in the ART

harmonization process with the GON. The goal of these activities is to facilitate the pharmacies' ability to

scale up capacity as patient utilization of ARV increases. Assessments of all facilities to determine

infrastructure needs have been conducted in COP07 and COP08 and will continue in COP09 for new sites.

These site capacity assessments have been the basis for efforts to strengthen the supply chain

management system for new sites. Ongoing assessments ensure sustainability of pharmacies and supply

chain management at the sites. All site pharmacists have participated in regular training sessions and work

with site data managers in providing regular supply chain information electronically to our central pharmacy.

The computerized supply chain information system linked through APIN Ltd. to patient clinical records also

provides reporting data for monitoring & evaluation (M&E) efforts at each site. In COP08, additional

logistician and supply chain management staff were hired to provide additional support in the

implementation of the supply chain management system.

Our long-term goal is to support a sustainable supply chain management system for ART program that

incorporates and bolsters existing Nigerian institutional structures. Continued collaboration with the GON

procurement efforts contribute to this goal. APIN Ltd. will also continue its efforts in systems strengthening

the existing pharmacies by sending technical staff from APIN Ltd. and Harvard to assess procedures within

these units. Recommendations for drug storage, equipping of pharmacies and minor renovations will be

considered. All APIN Ltd. pharmacists will complete the IDA ARV training program. Pharmacists hold

meetings on a quarterly basis and training updates are provided. Pharmacists and their data entry staff also

participate in the electronic data tracking system; regular training in computer entry and database

management are also provided by in country and US-based program management staff.

Activity Narrative: EMPHASIS AREAS

Emphasis areas include proper commodity and logistics system management and development of the

human capacity. Training initiatives have been incorporated into these activities in order to build the local

human resource capacity to manage a sustainable drug procurement and distribution system.

POPULATIONS BEING TARGETED

The primary target of these activities are health care workers, including program managers doctors, nurses,

and pharmacists who are involved in the drug procurement and distribution process. Furthermore, by

building mechanisms for drug procurement, these activities seek to target people living with HIV/AIDS

(PLWHA), both adults and children, who are in need of or already receiving ART care.

CONTRIBUTION TO OVERALL PROGRAM AREA

Through these activities we will have provided ARV drugs to 14,150 patients at 6 ART service outlets. In

addition, we have scaled up our PMTCT activities with 6 points of service providing access to PMTCT

services for 852 women. Through these activities, we will continue to strengthen the structure of the APIN

Ltd. ARV drug procurement system, as described above, in accordance with PEPFAR goals in order to

ensure cost effective and accountable mechanisms for drug procurement and distribution. Such capacity

building activities will focus on the transition of supply chain management from Harvard to APIN Ltd..

Furthermore, efforts to build local capacity through infrastructure building and training mechanisms are

consistent with PEPFAR 5-year goals to enhance the capacity of supply chain management systems to

respond to rapid treatment scale-up. Additionally, through procurement via SCMS, we seek to provide

support to efforts to build national capacity related to drug procurement and distribution.

Additionally, as part of our sustainability building efforts, APIN Ltd. will receive technical assistance and

support from Harvard to assume program management responsibility for the ARV Drug activities. This will

include the implementation of a plan to transition site oversight, management and training over to APIN Ltd..

The goal of such efforts is to provide for greater assumption of responsibility for management and

implementation of PEPFAR programming by Nigerian nationals through an indigenous organization.

LINKS TO OTHER ACTIVITIES

This activity also relates to activities in TB/HIV, Adult Care and Treatment, Pediatric Care and Treatment,

and Strategic Information. Through this activity, we will maintain significant linkages with PMTCT and Adult

and Pediatric Care and Treatment through the procurement of ART drugs for individuals served by these

programs. Additionally, we will develop and maintain linkages to TB/HIV activities, with expansion focusing

on co-locating ARV sites with existing DOTS sites. The supply chain management system will serve to

provide drugs to ART sites that are providing TB services in conjunction with ART services. SI activities will

provide crucial information for M&E as well as efficacy of the drug regimens, which may impact drug

procurement decision-making.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22509

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22509 22509.08 HHS/Centers for AIDS Prevention 9692 9692.08 $290,000

Disease Control & Initiative, LTD

Prevention

Table 3.3.15:

Funding for Laboratory Infrastructure (HLAB): $1,366,051

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

In COP09, the Harvard School of Public Health (Harvard) plans to move over 4 of its PEPFAR supported

sites to APIN Ltd. (APIN). The sites include Lagos University Teaching Hospital (LUTH), Nigerian Institute

of Medical Research (NIMR), Onikan Health Center, and Mushin General Hospital. The activity narrative

reflects the transfer of targets from Harvard to APIN. The activities will build on the structure and systems

put in place through Harvard. APIN will maintain a strong collaboration with Harvard University.

ACTIVITY DESCRIPTION:

In COP09, APIN will take over 4 APIN+/Harvard labs at a tertiary care institution and research institute. We

also propose to add additional expansion sites by building the infrastructure and capacities of 1 lab in

secondary health facilities in Lagos state to have capabilities for hematology, automated chemistry

analyzers, and laser-based lymphocyte subset enumeration. In COP08, we will expand the capacity of 1

lab in a primary health facility in Lagos state. We also expanded the capacity of the lab at Sacred Heart

Catholic Hospital, a secondary health facility in Ogun state, to have capabilities for hematology, automated

chemistry analyzers, laser-based lymphocyte subset enumeration and viral load assay.

By the end of COP09, HIV rapid testing will be performed at the HCT centers with the labs providing

supervisory roles. All 5 ART sites will have western blot capacity to confirm HIV status prior to initiation of

ART. HIV serology, hematology, chemistries, and CD4 enumeration will be supported at all secondary

hospitals with referral to the tertiary labs for PCR diagnostics and viral loads. Primary health care facilities

are closely partnered with secondary and tertiary care facilities, allowing for baseline and periodic

evaluation with full lab monitoring. The primary facilities provide limited lab monitoring with basic clinical,

hematologic and CD4 assays. We will screen for TB by sputum and/or pulmonary X-ray at all ART sites. We

will also provide screening for STIs, including Syphilis and Chlamydia at all of our sites. Our 2 labs with

infant PCR diagnostic capabilities (NIMR, LUTH) will continue to assist other PEPFAR IPs, using dried

blood spots (DBS) to test specimens from distant satellite sites.

Standardized lab protocols were developed in previous COP years by Harvard to accompany the clinical

protocols. Computerized lab results were also linked with patient records. In order to ensure continuity of

care and services, these protocols will continue to be implemented at APIN sites. These protocols include

provisions for the disposal of biomedical waste in accordance with good laboratory practices. Quality

assurance /quality control (QA/QC) policies have been developed and detailed annual assessments of all

lab activities are conducted. Quarterly QA/QC lab site visits are conducted by the APIN project

management team with technical assistance from Harvard and will use a standardized assessment tool

developed in Nigeria by the Lab Technical Working Group (LTWG). Results from the proficiency testing and

site visits will be sent into a centralized system within Nigeria, developed and supported by the PEPFAR

LTWG. External Quality Assurance (EQA) for lab tests was established in COP07 by Harvard and is

operational for CD4, HIV, HCV and HBV serology, chemistries, VL and HIV DNA PCR diagnostics through

individual lab registration with UK-NEQAS and CAP. We intend to continue this with all APIN labs. All PCR

labs will participate in the CDC Atlanta DBS DNA PCR proficiency program (EID QA). We provide support

for lab staff persons (based at sites), responsible for implementation of lab protocols, data entry and

performance of lab tests. In addition, we provide support for 3 APIN staff who provide technical assistance

to sites. We will continue our efforts to increase our laboratory technical staff in order to address increased

training and laboratory needs for the overall PEPFAR program.

Regular lab training allows the development of high quality lab standards in our PEPFAR labs and this has

been networked to our secondary and primary labs with specific tailoring to the needs and skills at each

level. In conjunction with Harvard Lab Infrastructure activities, staff at APIN sites will be linked to biannual

trainings provided on specific techniques/topics integrating QA/QC, good lab practices and lab safety.

Through Harvard, competency monitoring/evaluations and refresher trainings will be provided within

individual labs. APIN also provides support for a lab at NIMR (Lagos) which is a comprehensive hand-on

training center with lecture room capacity and personnel skilled in training. This training center provides

training in all areas, with special focus on viral load and drug resistance testing. Post Exposure Prophylaxis

(PEP) protocols have been implemented at each of our labs, supported under our ART drugs activities. In

COP09, we will continue our efforts to increase our laboratory technical staff in order to recruit staff

responsible for lab QA, lab training and monitoring for APIN.

A laboratory information system (LIS) will be implemented at sites, with appropriate capabilities, to

streamline the capture of lab data to minimize transcription errors and facilitate data entry and results

output.

We will participate in LTWG monthly meetings to ensure harmonization with other IPs and the GON,

including the development of a common lab equipment platform (appropriate for each lab level).

Procurement of lab reagents is structured in two ways. Reagents available in Nigeria will be procured

directly by the sites from specific distributors. Labs will be advised to maintain a 3 month reagent buffer.

Most reagents needing importation will be ordered at Harvard and shipped to the APIN Central Medical

Stores warehouse in Lagos. PEPFAR funding supports procurement of lab equipment, generators and

water purifiers necessary for lab work at APIN sites. Equipment costs for labs can be high in the first year,

but represents significant infrastructure development. Maintenance costs include minimal renovation costs

for some labs, replacement of small lab equipment and training costs for additional personnel.

APIN will perform 267,086 tests in COP09, including HIV diagnosis and tests for disease monitoring

including CD4 enumeration, PCR diagnosis of infants and VL, which provide support for ARV treatment for

13,100 adult and 1,050 pediatric patients at APIN sites in Lagos and Ogun states. In addition, we seek to

train199 lab staff members in COP09.

EMPHASIS AREAS:

This program seeks to address gender equity by building the capacity of labs at affiliated sites to conduct

Activity Narrative: testing related to PMTCT. Increased lab capacity will permit the sites to provide equitable treatment for both

women and men. We also place emphasis on TB services as our lab activities include the provision of

support for TB and HIV diagnostics at 43 TB DOTS sites in Oyo state.

POPULATIONS BEING TARGETED:

This program targets public and private health care workers with training to maintain high quality lab

standards. Laboratory diagnostics and monitoring supported through these activities also target PLWHAs

who are provided with treatment through our Adult and Pediatric Care and Treatment activities.

CONTRIBUTION TO OVERALL PROGRAM AREA:

These activities contribute to the goal of maintaining high quality services as the PEPFAR program

expands. Training lab staff will assist in building the human resource capacity of our sites to provide

sustainable lab support to sites providing high quality HCT and ART treatment. Two labs at a tertiary care

hospital and research institute will have the capacity to perform early infant diagnosis (EID) by HIV DNA

PCR. These labs are also linked to PMTCT sites, to provide a mechanism for EID as a part of the PEPFAR

supported national scale-up plan (consistent with 2009 PEPFAR objectives for Nigeria). APIN will partner

with Harvard, GON and Clinton Foundation for procurement of EID test kits and specimen collection

supplies and transportation of DBS/results to and from testing labs. The NIMR PCR lab will provide QA

support for the EID program in the southern half of Nigeria (through retesting). Through a tiered system of

labs at tertiary, secondary and primary sites we are able to ensure that patients at community based

primary facilities are provided with a full complement of lab monitoring as a part of ART treatment and care.

Our training activities include management and competency training, which seeks to build sustainability.

Additionally, as part of our sustainability building efforts, APIN will receive technical assistance and support

from Harvard to assume program management responsibility for our Lab Infrastructure activities. This will

include the implementation of a plan to transition site oversight, management and training over to APIN. The

goal of such efforts is to provide for greater assumption of responsibility for management and

implementation of PEPFAR programming by Nigerian nationals through an indigenous organization.

LINKS TO OTHER ACTIVITIES:

These activities relate to activities in PMTCT, Counseling & Testing, Palliative Care TB/HIV, Adult Care and

Treatment, Pediatric Care and Treatment and OVC. Our labs are crucial in providing adequate HIV

diagnostics in PMTCT, HCT, OVC, Palliative care and ART services. Furthermore the lab provides other

diagnostics such as OIs. As a part of this activity, we seek to build linkages between labs and our patient

care sites in order to ensure that lab information is fed back into patient records for use in clinical care. Our

SI activities provide support in M&E, including data management of testing results.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22507

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22507 22507.08 HHS/Centers for AIDS Prevention 9692 9692.08 $200,000

Disease Control & Initiative, LTD

Prevention

Emphasis Areas

Gender

* Increasing gender equity in HIV/AIDS programs

Health-related Wraparound Programs

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $85,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.16:

Funding for Strategic Information (HVSI): $391,372

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

In COP09, the Harvard University plans to move over four of its PEPFAR supported sites to APIN, Ltd

(APIN). The sites include Lagos University Teaching Hospital (LUTH), Nigerian Institute of Medical

Research (NIMR), Onikan Women's Hospital (OWH), and Mushin General Hospital (MGH). Forty-three DOT

(Directly Observed Treatment) centers in Oyo State will also be supported. The activity narrative reflects the

transfer of targets from Harvard to APIN. The activities will build on the structure and systems put in place

through Harvard. APIN will maintain a strong collaboration with Harvard University.

NARRATIVE:

During COP08, APIN assumed management responsibility for 2 Harvard sites, Sacred Heart Catholic

Hospital in Lantoro, Ogun State and Primary Health Center-Iru on Victoria Island, Lagos. In COP09, APIN

will take over provision of OVC services at an additional 4 sites (LUTH, NIMR, OWH, and MGH). In COP09,

APIN will provide support for SI activities at all 6 sites (3 ARV, 2 PMTCT sites, 1 PHC, and 43 DOT sites).

The activities include: data management and data quality assurance, monitoring and evaluation (M&E),

health management information systems (HMIS) and operational research studies in all supported sites.

Funds will also be utilized to continue building the capacity of site staff in the above areas in order to

promote effective use of data to improve services and programs as well as influence policy. In addition, a

major goal in the coming year is to further achieve sustainability. In order to attain that goal, APIN will

receive technical assistance from Harvard in the area of data expertise. APIN staff, which includes a

database specialist, IT specialist, an M&E Officer, and an M&E Consultant, will assist the sites with on-site

clinical, pharmacy, laboratory and project reporting. In line with the PEPFAR-Nigeria indigenous capacity-

building strategy, APIN, in collaboration with Harvard, will strengthen local capacity at primary, secondary

and tertiary health facilities. A major goal of our activities this coming year is to further: 1) build M&E

capacity at the local level; 2) promote increased utilization of data in evidence-based decision making; 3)

evaluate clinical outcomes and intervention efforts; and 4) evaluate program outcomes.

The APIN program will utilize a relational database system developed through Harvard PEPFAR. The

database is linked by a unique patient ID number and contains data required for patient management and

monitoring (PMM). The electronic database is functional and fully harmonized to the GON PMM forms to

allow for full integration into the broader Nigerian national health information system. The database will be

strengthened to track linkages for prevention-care-treatment or the continuum of HIV services. Throughout

the transition of activities from Harvard to APIN, we will continue to use the APIN+/Harvard forms and

databases which were developed under COP funding to Harvard in previous grant years. The APIN/Harvard

forms collect clinical visit, pharmacy pick-up, laboratory assessment, toxicity, virological/immunological

failure and discontinuation information for adult and pediatric care and treatment as well as PMTCT

services. At present, OVC data are collected using GON registers, but we are working to develop electronic

forms, which are fully harmonized with the GON forms, and will allow for more efficient reporting. The

program has also developed a number of utilities to maximize the efficient use of data for improved patient

management, data quality, reporting and program management. This includes a treatment response utility,

which provides a graphical display of patients' CD4 counts, viral loads (as clinically necessary), and drug

pick-up history, as well as a loss to follow-up utility, which serves as an early warning system for patients

that miss drug pick-ups. Information is generated and used for site and program-specific evaluation of

services, such as assessment of CD4 counts, viral load (as clinically necessary), adherence, and loss to

follow-up.

APIN will continue to maintain computer hardware and software provided by Harvard to support sites as

services are being maintained. SOPs are in place to govern data entry, security, management and reporting

based on the ARV treatment and care protocol. Refinement of instruments and databases is ongoing to

accommodate program reporting requirements from Harvard, USG and the GON. The PMM forms are

stored in the patient hospital folders and kept in locked file cabinets. National registers are also in use at

APIN-supported sites. Data from PMM forms and relevant registers are entered into the databases by

trained data entry staff at the respective sites. The data are then uploaded to a password protected web

server, accessible to authorized personnel and data managers at the Nigerian sites and at APIN/Harvard.

Data managers prepare timely reports for GON and USG using the electronic databases. Facility-based

data are reported using harmonized national reporting system. The Boston and Nigerian data management

team and the M&E officer provide regular feedback on data collected and on reports to the sites. Site M&E

committees are in place to implement an annual M&E plan; M&E results are fed back to the sites to promote

systems improvement.

APIN will continue to improve its good working relationships with state-level M&E staff through regular

communication, on-site monitoring activities, active work at capacity-building, championing the "Three

Ones" at the state level, and participation in routine state-level monitoring and reporting events that include

non-APIN supported sites in the states. These actions are designed to encourage state M&E officers'

participation in strategic information activities and expand their capacity in data collection, management,

reporting and strategic utilization. This involvement will build the capacity of the state-level staff and

promote sustainability. The SI team of APIN and Harvard will continue to participate actively in the National

M&E technical workgroup (TWG) and the USG-Nigeria SI TWG and respond to the goals of the one

national reporting system.

In COP09, APIN will scale up the quality improvement (QI) activities to all the APIN sites, building on the

Harvard supported internal QI initiative, designed at collecting qualitative and quantitative data regarding

indicators on the provision of adult, pediatric and PMTCT services at each site. In order to continually

improve and monitor data quality, each site will be visited regularly by APIN M&E staff throughout COP09;

on-site TA and supportive supervision will be provided. Regular inter-site interactions will be encouraged,

facilitated by APIN+/Harvard personnel. In COP08, all supported sites constituted M&E committees; these

committees meet to evaluate the site M&E data and use the information towards improving quality of care

and making evidence-based clinical decisions. In COP09, sites will work on fully developing QA/QI

committees to conduct quarterly reviews of quality of care. During COP09, we will continue to encourage

and monitor the activities of the site M&E and QA/QI teams. We are also working on developing a database

utility that will allow the sites to quickly pull out data on patients that are lost to follow-up, showing signs of

Activity Narrative: toxicity or failure, or that may require other focused attention, to further improve quality of care. Finally,

HIVQUAL using additional QI indicators is being implemented in six selected APIN supported sites.

In COP09, 49 local organizations will be provided with technical assistance for strategic information

activities and 161 individuals will be trained in database management, monitoring and evaluation (M&E),

surveillance, and HMIS. The APIN central office will conduct 10 training sessions centrally. In addition,

regional data management trainings for personnel working with medical records and patient data will be

conducted on a regular basis. Data management and M&E modules will be incorporated into respective

technical training for other disciplines such as clinicians, nurses, pharmacists and laboratory staff etc.

EMPHASIS AREAS:

These activities emphasize monitoring, evaluation, and reporting through data collection, data analysis, data

use and data dissemination. Emphasis is placed on strategic information, human capacity development and

local organization capacity-building.

This activity will highlight gender issues by providing gender disaggregated data on patients accessing

HIV/AIDS related services. Through this analysis, we will be able to contribute to national surveillance on

utilization of HIV services and impact of HIV intervention on both sexes. This data will be essential to the

development of outreach, treatment programs and education to reach an equitable number of men and

women.

TARGETED POPULATIONS:

The SI activities target program managers and M&E officers, site coordinators and principal investigators to

provide them with skills and tools for programmatic monitoring/evaluation. The data collection and

management components of these activities target medical record staff, data staff, and other health care

workers who are involved in the implementation of these processes. Lastly, the M&E and capacity-building

efforts target implementing organizations, including private, community-based and faith-based organizations

involved in the provision of ART, HCT, pediatric and adult BC&S, TB/HIV and PMTCT services.

CONTRIBUTIONS:

SI activities supported by APIN are consistent with the 2009 PEPFAR goals to build indigenous capacity-

building in the area of SI. APIN SI activities are consistent with these goals in that funding will be used to

strengthen local capacity in the area of database management, data analysis, data use, M&E and QA/QI.

Harvard will also provide SI support to its local administrative office, central pharmacy and warehouse.

Additionally, as part of our sustainability building efforts, APIN with technical assistance and support from

Harvard will assume program management responsibility for the SI activities. The goal of such efforts is to

provide for greater assumption of responsibility for management and implementation of PEPFAR

programming by Nigerian nationals through an indigenous organization.

LINKS TO OTHER ACTIVITIES:

These activities are linked to PMTCT, OVC, TB/HIV, HCT, ART, and Basic Care & Support Services, where

SI is used for M&E and QA/QI. In M&E activities, APIN will link to the National M&E TWG and Nigeria

MEMS. Additionally, through the provision of IT support and data management personnel, APIN will

provide linkages between all supported sites as related to data sharing and HIV surveillance in PEPFAR

program areas. Through operational research studies, APIN will collaborate with Harvard, FMOH, other

GON representatives, NNART committee and the NIAID/NIH.

New/Continuing Activity: Continuing Activity

Continuing Activity: 22506

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

22506 22506.08 HHS/Centers for AIDS Prevention 9692 9692.08 $50,000

Disease Control & Initiative, LTD

Prevention

Emphasis Areas

Gender

* Increasing gender equity in HIV/AIDS programs

Health-related Wraparound Programs

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $20,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.17:

Subpartners Total: $9,686,286
Agbongbon Maternity Centre: $6,098
Alafia Hospital: $6,098
Alhaja Sarat Adesina Health Centre: $6,098
Baptist Medical Centre: $6,098
Baptist Medical Centre: $6,098
Comprehensive Health Center: $6,098
Comprehensive Health Center: $6,098
Iseke Maternity Centre: $6,098
Jaja Clinic: $6,098
Lagos University Teaching Hospital: $3,159,925
Lam Adesina Health Centre: $6,098
Maternity Center: $6,098
Moniya Health Centre: $6,098
Mushin General Hospital: $350,200
Muslim Hospital: $6,098
National Institute for Medical Research - Tanzania: $3,474,145
Nigerian Institute for Medical Research: $833,943
Our Lady of Apostles, Iseyin: $6,098
General Hospital, Onikan: $337,829
Primary Health Care Centre, Adifase, Apata, Ibadan: $6,098
Primary Health Care Centre, Agede, Kisi: $6,098
Primary Health Care Centre, Ago-Are: $6,098
Primary Health Care Centre, Alafara Oje, Ibadan: $6,098
Primary Health Center, Anko Eruwa: $6,098
Primary Health Center, Apete, Ibadan: $6,098
Primary Health Center, Boomi, Igboho: $6,098
Primary Health Care Centre, Ilora: $6,098
Primary Health Care Centre, Igbeda: $6,098
Primary Health Care Centre, SDP Secretariat, Ibadan: $6,098
Primary Health Center, Igbeti: $6,098
Primary Health Center, Ijaye: $6,098
Primary Health Center, Ikereku: $6,098
Primary Health Center, Iwo Road, Ibadan: $6,098
Primary Health Center, Molete, Ibadan: $6,098
Primary Health Center, Ojaigbo, Ogbomoso: $6,098
Primary Health Center, Oja-Oba, Iseyin: $6,098
Primary Health Center, Omi-Adio: $6,098
Primary Health Center, Oyo: $6,098
Primary Health Center, Saki: $6,098
Primary Health Center, Yidi Agunpopo, Oyo: $6,098
Primary Health Center, Igbo-Ora: $6,098
Primary Health Center, Lagelu, Agugu, Ibadan: $6,098
Primary Health Center, Olomi, Ibadan: $6,098
Primary Health Center, Oniyanrin, Ibadan: $6,098
Primary Health Center, Out: $6,098
Primary Health Care Centre, Victoria island, lagos: $181,690
Catholic Lantoro Hospital: $1,028,667
State Hospital, Oyo: $6,098
University of Ibadan: $63,771
University of Ibadan: $6,098
Cross Cutting Budget Categories and Known Amounts Total: $390,026
Human Resources for Health $28,000
Human Resources for Health $64,000
Human Resources for Health $32,000
Food and Nutrition: Commodities $11,780
Water $21,178
Food and Nutrition: Commodities $5,890
Water $21,178
Human Resources for Health $20,000
Human Resources for Health $20,000
Human Resources for Health $60,000
Human Resources for Health $1,000
Human Resources for Health $85,000
Human Resources for Health $20,000