Detailed Mechanism Funding and Narrative

Years of mechanism: 2008 2009

Details for Mechanism ID: 3568
Country/Region: Mozambique
Year: 2009
Main Partner: Columbia University
Main Partner Program: NA
Organizational Type: University
Funding Agency: HHS/CDC
Total Funding: $17,224,418

Funding for Biomedical Prevention: Prevention of Mother to Child Transmission (MTCT): $0

This PHE activity, "Moving from single dose Nevirapine to more complex antiretroviral prophylactic

regimens in PMTCT programs: assessing implementation successes and barriers", was approved for

inclusion in the COP. The PHE tracking ID associated with this activity is MZ.07.0087.

Continuing Activity: Replacement Narrative

The Columbia University International Center for AIDS Care and Treatment Programs (ICAP) will complete

implementation of the PHE, "Moving from single dose Nevirapine to more complex antiretroviral prophylactic

regimens in PMTCT programs: assessing implementation successes and barriers." This activity was

previously titled "Assessment of access, uptake and adherence to single-dose nevirapine (sdNVP)

prophylaxis among HIV-infected pregnant women." Since this project was conceptualized for FY06

planning, rapid changes have occurred in international standards for PMTCT practice, and MOH guidelines

have been revised. The protocol has been updated accordingly, and the scope has been expanded to move

beyond sdNVP to include complex ARV prophylaxis regimens.

This activity was conceptualized in FY06; new MOH PMTCT program direction and staff reorganization in

the PMTCT program has significantly delayed progress during the first year. At this time, these institutional

issues have stabilized. ICAP has significantly expanded their Mozambique-based research team.

At the moment the protocol is under final revision with headquarter & Mozambique in-country teams. The

protocol is planned to be submitted to appropriate local and US-based IRBs in October 2007. The

implementation is expected to be concluded in January 2009. Principal investigators are Dra. Lilia Jamisse,

MOH Adjunct National Health Director, and Dra. Elsa Jacinto, MOH Reproductive Health Program Director

and PMTCT Program Coordinator.

The main objectives of the study are: 1) To identify patient-level determinants of maternal and pediatric

PMTCT outcomes; 2) To identify contextual, programmatic and site-level determinants of maternal and

pediatric PMTCT outcomes; 3) To identify facility and program level characteristics that are associated with

HIV care and treatment outcomes, after adjusting for patient-level characteristics.

This study will include retrospective and prospective cohort follow-up with data from medical records and

interviews with women as well as a descriptive study of site and program characteristics. This work is vital

to identifying important programmatic aspects of HIV care and PMTCT programs for use in planning future

programs and improving existing ones in Mozambique and elsewhere.

Work will start in the field in January 2008. Findings will be shared with participants, study sites and ICAP

supported sites involved. It is also in the public interest that findings be made available to a broader range

of HIV/AIDS health care providers.

Stakeholders (MOH, USG, ICAP) will participate in the planning and presenting of the data at meetings and

conferences, as well as disseminating information through routine channels within the USG PMTCT

partners community and MOH organizational structure. Results will be submitted for publication in an

appropriate peer reviewed journal.

The estimated costs are USD 220,000; USD 70,000 will be continue to be rolled over from the FY06 budget,

and in FY08 an additional USD 150,000 is requested to fund completion of the project.

Budget justification: 1) Personnel: USD 90,000; 2) Equipment: USD 18,000; 3) Supplies: USD 10,000 4)

Travel: USD 40,000; 5) Dissemination of findings: USD 12,000; 6) Training (material development and

courses), USD 15,000; 7) Other: USD 35,000.

Participant incentives will not be issued as per current MOH guidance.

New/Continuing Activity: Continuing Activity

Continuing Activity: 16288

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16288 16288.08 HHS/Centers for Columbia 7403 3568.08 Track 1 ARV $150,000

Disease Control & University Moz

Prevention Supplement

Emphasis Areas

Human Capacity Development

Public Health Evaluation

Estimated amount of funding that is planned for Public Health Evaluation $0

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.01:

Funding for Biomedical Prevention: Prevention of Mother to Child Transmission (MTCT): $0

This PHE activity, "Evaluation of eligibility for ART in Mozambique by clinical staging performed for HIV-

infected pregnant women by ANC/PMTCT personnel and comparison to CD4 and total lymphocyte count",

was approved for inclusion in the COP. The PHE tracking ID associated with this activity is MZ.07.0086.

Continuing activity: Replacement narrative

Evaluation of eligibility for Anti-Retroviral Therapy (ART) in Mozambique by clinical staging performed for

HIV-infected pregnant women by antenatal care / prevention of mother-to-child (ANC/PMTCT) personnel

and comparison to CD4 and total lymphocyte count (TLC)

This project aims to evaluate techniques used for determining ART eligibility among pregnant women by

comparing various algorithms of clinical staging, CD4 count, total lymphocyte count, and

hemoglobin/hematocrit. Sensitivity and specificity of these tools will be compared when used by maternal

child health (MCH) nurses in the context of ANC PMTCT services in Mozambique. The study will help

determine the best method for evaluating eligibility for ART among pregnant women, in particular for sites

with limited or no access to laboratory services.

The Mozambican Ministry of Health (MOH) National PMTCT protocols currently recommend initiation of

ART for pregnant women if they are stage III or IV, or have a CD4 of less than 250/mm3 . While a network

of laboratories is being established with PEPFAR support that will in the future increase access to CD4

testing, many remote PMTCT sites will not have easy access to laboratory services for the next years. This

fact, coupled with the scarcity of skilled and trained personnel available to clinically assess patients leads to

a large contingent of HIV-infected pregnant women who are not adequately assessed for ART eligibility.

As part of conducting this PHE, training in clinical staging will be provided for participating nurses.

This activity was conceptualized in FY06 but protocol has not yet been finalized. New MOH PMTCT

program direction and staff reorganization in the PMTCT program has significantly delayed progress during

the first year. At this time, these institutional issues have stabilized. ICAP, the proposed USG implementing

partner, has significantly expanded their Mozambique-based research team. Money will be reprogrammed

from FY06 to Columbia University International Center for AIDS Care and Treatment Programs (ICAP) to

collaborate and facilitate study administration and logistics. Additional FY08 funding will also be allocated to

support completion of this activity. CDC Mozambique is actively recruiting a study coordinator who is

expected to be in place by late September or early October, 2007, to function as the lead for this activity.

To date, discussions to refine study design and implementing issues have taken place. A draft protocol has

been developed and will be presented and shared with implementing partners and other MOH staff

involved. The protocol and instruments will be vetted through the appropriate ethical reviews in the US as

well as the Mozambican Bioethics Committee in country. Principal investigators are Dra. Lilia Jamisse,

MOH Adjunct National Health Director, and Dra. Elsa Jacinto, MOH Reproductive Health Program Director

and PMTCT Program Coordinator.

Stakeholders (MOH, USG, ICAP) will participate in the planning and presenting of the data at meetings and

conferences, as well as disseminating information through routine channels within the USG PMTCT

partners community and MOH organizational structure. Results will be submitted for publication in an

appropriate peer reviewed journal.

After the protocol has been cleared by the appropriate ethics boards, the assessment will take place in two

ICAP-supported PMTCT sites, with laboratory support available either on site or within proximity at the

provincial hospital laboratory. Three potential sites are currently under evaluation, and initial site

assessments have taken place. Staff will be trained in assessing patients in clinical staging according to

WHO guidelines; initial development of materials has started and is expected to be completed by

September-October 2007.

Study activities and data analysis are expected to be complete by the end of FY08.

Budget Justification: $150,000 will be rolled over from FY06/FY07 and reprogrammed to Columbia. To

enable completion of the project, $37,500 in additional funds will be allocated for FY08.

Cost centers will be 1) Personnel support, $68,000; 2) Equipment, $26,000; 3) Supplies, $12,000; 4) Travel

and specimen transport, $38,000; 5) Training (material development and courses), $23,500; 6)

Dissemination meetings, $12,000; 7) Other, $8,000.

Participant incentives will not be issued as per current MOH guidance.

New/Continuing Activity: Continuing Activity

Continuing Activity: 16286

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16286 16286.08 HHS/Centers for Columbia 7403 3568.08 Track 1 ARV $37,500

Disease Control & University Moz

Prevention Supplement

Table 3.3.01:

Funding for Biomedical Prevention: Prevention of Mother to Child Transmission (MTCT): $4,950,000

Summary and background ($4,950,000)

In FY09 Columbia University (CU) / ICAP will continue PMTCT support at 41 existing sites (including 2

model centers) and expand to absorb 24 USG-supported facilities with PMTCT services in Maputo City,

Zambezia and Gaza. Transition between USG partners will start following planning meetings including

CDC and district-level MOH (DPS). In addition ICAP support for comprehensive PMTCT services will

expand to 13 sites in Maputo City, Inhambane and Nampula.

CU will emphasize Health System Strengthening (HSS) at provincial (DPS) and DDS levels, developing

capacity in PMTCT Clinical Mentoring and management of district teams. CU will work with DPS and DDS

to support supervision and, in turn, scale up comprehensive PMTCT care at all sites. CU will roll out

counseling and testing at sites and strengthen linkages between PMTCT & ART services. CU will enhance

infant & child initiatives to increase enrollment and retention in care, ART initiation, access to adequate

infant feeding, and counseling and support services. Activities will include building maternal and child health

(MCH) staff capacity, strengthening coordination with the early infant diagnosis (EID) program, developing

infant feeding tools, piloting the provision of micronutrients, implementing infant feeding support groups and

revitalizing the Baby Friendly Hospital Initiative.

(1) Support for comprehensive PMTCT Activities - continuation and expansion ($3,235,000)

Integration of PMTCT into HIV care & treatment services is critical to provide more effective PMTCT

interventions for HIV-infected pregnant women. CU will continue to emphasize this comprehensive

approach, building on MCH services, focusing on access to ART and more complex PMTCT regimens, as

well as cotrimoxazole (CTX) prophylaxis for women in ANC. CU will also enhance MCH services, including

training for providers in CTX prophylaxis based on WHO guidelines, provision of malaria prophylaxis to

pregnant women including ITNs in coordination with PMI, strengthening TB screening, continued support for

dual protection and integrating HIV counseling and testing (CT) into family planning (FP) services.

Integration and uptake of FP services has been weak in Mozambique, and has not been a focus of USG

Mozambique. ICAP will increase efforts to improve access to FP services for HIV-infected women,

particularly post-partum (including coordination of postpartum visits and FP services).

In order to increase ART initiation amongst pregnant women, CU will continue to build a PMTCT network

focused on integrated services in ART clinics, as well as strengthening referral systems between PMTCT

and ART services. At model centers, HIV treatment will be integrated into PMTCT services, coordinated

through an MCH-focused ART committee to facilitate rapid initiation of ART for pregnant women.

In FY09, the proportion of women initiating ART will increase to 20% (2673) from 8% in FY08, among all

women receiving ARV's for PMTCT. Consequently the proportion of women receiving single-drug regimens

with sdNVP and AZT will decrease from 28% to 20%, and 62% to 60%, respectively. Activities to optimize

adherence and retention in care include enhancing patient support by training MCH staff in skills and quality

of care with a focus on adherence monitoring and counseling, group management skills, and psychosocial

support. CU will expand mother support groups to 24 sites (8 in Maputo, 5 in Zambezia/Gaza, 4 in

Inhambane). In Nampula, mothers2mothers will implement their model in 17 support groups. IEC

materials for patients & health care staff to guide group sessions will be developed.

Promotion of male-friendly models of care in MCH will be expanded by distributing written invitations to all

pregnant women at ANC & increasing MCH staff motivation to involve men by conducting sensitization

sessions during regular monitoring meetings.

Peer educators will be trained in outreach services/defaulter tracing to improve adherence and increase

treatment literacy. Activities will include capacity building of expert patients in PMTCT and HIV care and

treatment, designing materials appropriate for low-literacy audiences and PMTCT training of trainers for

peer educators.

Traditional birth attendants (TBAs) will continue to promote mother-infant follow up and ensure linkages

between the community & MCH sector. Four trainings will be held in Nampula and Inhambane to build TBA

capacity. Supervision and stipend/incentives for home-based care will be provided.

Support for infant/child health care initiatives will also be incorporated as part of the PMTCT continuum.

Regular follow up of women & children is required to promote safe infant feeding practices and improve

infant outcomes. To optimize adherence and retention in care, CU will provide nutrition education and

counseling targeted at pregnant women and infants, micronutrient sprinkles for porridge fortification, and

linkage to supplementation and food security programs. In addition new infant feeding support groups will

be developed at 16 sites and continued at 14. Promotion of early initiation of breastfeeding and good

practices in HIV context will continue at all sites by training 80 health staff at ANC and Maternities. The

Baby Friendly Hospital Initiative will be revitalized at 48 maternities and daily breastfeeding group sessions

for all women delivering in maternity will be promoted.

Infant and child health care initiatives will be prioritized by rapid identification of HIV exposed infants,

implementation of a referral system, and early consistent follow up of HIV exposed infants in at-risk child

consultations (CCR). EID training and mentoring of health staff on linkages between EID and MCH services

will be coordinated to improve patient follow-up. "Family days" will be supported at facilities with both

PMTCT and ART services.

(2) Supporting and strengthening MOH district health teams to scale up PMTCT and expand PMTCT

coverage ($420,000)

Using a district team approach, CU will expand support to PMTCT in 8 districts in Nampula, Inhambane,

Zambezia and Gaza. Funds will be used for on-site mentor training to enhance supervisory skills, as well

as site assessments to improve patient services and flow. Support will also be provided to ensure

consistent stock of ARV drugs and other necessary materials by strengthening the link between PMTCT

and pharmacy services. CU will work with SCMS to develop feedback systems for supply management at

DDS/DPS level. In the shift from direct site support to district level health systems strengthening, CU will be

lead partner in Nampula, Inhambane and Maputo City and proposes PMTCT TA positions for Nampula and

Inhambane to strengthen DPS capacity.

CU will continue to build capacity by supporting district and facility level trainings in all districts to improve

quality of M&E for PMTCT. At a national level, in collaboration with the MOH PMTCT Technical team, CU

will support review of program registers & assist in strengthening data links between PMTCT, care &

treatment, and infant follow up services. National M&E support will emphasize quality assurance. CU will

provide a fully seconded technical advisor to the MOH, as well as develop an electronic patient tracking

system & implement a national database.

Activity Narrative: CU will continue FY08 activities, including development and piloting of the PMTCT patient database to track

HIV+ mothers across health systems (ANC, maternity, care & treatment and CCR).

(3) Human capacity development ($1,095,000)

PMTCT Clinical Mentoring was launched in FY08 at model centers, which will continue to serve as

reference centers providing support at a provincial level. Trained mentors will conduct routine supervisory

visits at sites in order to ensure delivery of quality services consistent with national PMTCT guidelines.

Additionally, CU will start Clinical Mentoring in 8 more districts. A total of 50 staff from district teams will be

trained as mentors/supervisors to oversee PMTCT program implementation at district level, and 92 nurses

from peripheral sites will participate in the mentoring rotation. During FY09, CU will continue collaboration

with I-TECH to evaluate and revise PMTCT clinical mentoring tools.

CU will support DPS level trainings to increase number of MCH staff trained in PMTCT, including CT, infant

follow-up. and safer infant feeding practices.

(4) Central-level MOH Personnel Support ($200,000)

CU will support the MOH by providing direct TA to PMTCT M&E activities as mentioned above. Efforts will

also focus on improving district-level utilization of data, including feedback to site level. Due to the lack of

PMTCT support within the MOH, CU will continue to provide a data entry clerk to help with PMTCT program

monitoring as well as an admin assistant to facilitate internal MISAU coordination and communication

between MISAU and partners and program implementers.

New/Continuing Activity: Continuing Activity

Continuing Activity: 16284

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16284 5208.08 HHS/Centers for Columbia 7403 3568.08 Track 1 ARV $3,165,000

Disease Control & University Moz

Prevention Supplement

8567 5208.07 HHS/Centers for Columbia 4859 3567.07 UTAP $2,603,125

Disease Control & University

Prevention

5208 5208.06 HHS/Centers for Columbia 3567 3567.06 UTAP $1,091,000

Disease Control & University

Prevention

Emphasis Areas

Gender

* Addressing male norms and behaviors

* Increasing gender equity in HIV/AIDS programs

Health-related Wraparound Programs

* Malaria (PMI)

Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Estimated amount of funding that is planned for Food and Nutrition: Policy, Tools $300,000

and Service Delivery

Food and Nutrition: Commodities

Estimated amount of funding that is planned for Food and Nutrition: Commodities $75,000

Economic Strengthening

Education

Water

Table 3.3.01:

Funding for Care: Adult Care and Support (HBHC): $177,585

THIS ACTIVITY SHEET WAS MODIFIED IN THE FOLLOWING WAYS:

Columbia University's (CU) scale-up of treatment services is supported by USG and guided by

Mozambique's national HIV strategic plan. In collaboration with the Ministry of Health (MoH), CU will

continue support 42 HIV care and treatment facilities at various stages of development and expansion in

Maputo City, Gaza Province, Inhambane Province, Nampula Province, and Zambezia Province. CU also

plans to initiate support at 12 additional facilities. Expansion plans are in accordance with MoH policy.

Special emphasis will be maintained on the decentralization/integration process with special regard to urban

settings. Major urban treatment facilities will be enabled to down refer stable patients on treatment and

urban Health Centers will be able to start new patients on TARV. Complicated cases and treatment failures

will be managed at bigger facilities. This is a part of a national process of decentralization that, according to

initial MoH chronogram should be completed by December 2009.

Support to clinical services includes technical support to diagnosis, prophylaxis and treatment of

opportunistic infections including pain management. On the job training activities and formal training at site

and provincial level includes the OI component. At facilities where CU is supporting major renovations, the

physical space allows areas for cytostatics preparation and administration for SK. CU supports the training

of staff on cystostatic preparation and on Kaposi Saroma treatment.

CU will continue to facilitate the nutritional assessment and distribution of nutritional supplements to patients

through mechanisms to be determined in partnership with USAID on the basis of MoH approved clinical

criteria at Maputo Military Hospital. (420 beneficiaries)

CU will maintain and expand the monitoring and evaluation system that captures valuable information on

opportunistic infections and will continue to work with clinical staff to improve the quality of filling in forms.

This will be done through periodic site visits to sites from the provincial data officers and with the support

from M&E technical staff from the central office.

Educational activities carried out through peer educators and support groups will include messages

regarding CTX prophylaxis, nutrition and hygiene education.

CU will work to establish partnerships with community organizations working on Home Base Care to link

health facility services with home care.

Total: $177,585

FY08: Columbia University works in 7 provinces in Mozambique (Maputo, Gaza, Inhambane, Nampula,

Zambezia, Maputo City, and Tete province where Columbia works with the military to provide services. In all

these sites, support is provided for the implemention of HIV care and treatment programs that include staff

training and mentoring, infrastructure improvements, procurement of materials and supplies needed at

facility level, hiring of staff to support service provision and program monitoring and evaluation, as well as

technical and clinical advisors. These activities are also described in other parts of this document.

During FY08 Columbia University-ICAP will continue to support and expand HIV related care activities at

these sites with a view of decentralising services to remote facilities while improving patient follow up,

referral and initiation of ART services. The following activities will be implemented:

1. Strengthen the management OI drugs at supported Care and treatment facilities through: training of

pharmacy staff in OI management including how to monitor adherence; implementation of drug

management systems (computer and paer based), support provincial warehouse to strenghthen referral

systems, logistics systems and staff training in drug managment; Procurement of OI medication for

treatment of adults, infants and children in case of stock outs at CU supported sites: additionally CU will

continue to work with the MOH and SCMS in ensuring that sites implement recommended drug mangment

procedures to strenghthen the current logistics system.and Implement logistic systems to help ensure

continuous supply of medications (in coordination with CMAM/SCMS);

2. Support the diagnosis and treatment of Opportunistic Infections: Implement syndromic approach for

treatment of STIs and screening for HPV/cervical cancer through training and procurement of equipment

and supplies;. Implement case-finding, prevention and treatment of Malaria through training and in

collaboration with PMI and the PSI programs, procurement of bed nets and other supplies; Support

improvement and expansion in the detection and treatment of Kaposi's Sarcoma through training health

staff in chemotherapeutic agents preparation/KS treatment, renovation and outfitting of treatment areas, and

implementation of an M&E system to track incidence and prevalence of KS; Implement patient follow up for

patients not yet initiating ART ensuring that they receive cotrimoxazole, have access to nutrition programs

(World Food Program) are followed up regularly and initiated on ART once they are eligible for treatment

3. Improve links with community HIV care programs through development of Memoranda of understanding,

sub-agreements, with Comunity based organistaions and PLWHA support groups.

Support diagnosis, treatment and prevention of opportunistic infections: Implement syndromic approach for

treatment of STIs and screening for HPV/cervical cancer; Provide training, lab testing, and procurement of

equipment and supplies for diagnosis and t

Strengthening OI management by providing training to pharmacists, implementation of software ,

monitoring of adherence , continued education for health staff, supervision and M & E and procurement of

essential Oi drugs

New/Continuing Activity: Continuing Activity

Continuing Activity: 16283

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16283 5198.08 HHS/Centers for Columbia 7403 3568.08 Track 1 ARV $640,000

Disease Control & University Moz

Prevention Supplement

8566 5198.07 HHS/Centers for Columbia 4859 3567.07 UTAP $680,000

Disease Control & University

Prevention

5198 5198.06 HHS/Centers for Columbia 3567 3567.06 UTAP $380,000

Disease Control & University

Prevention

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $75,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Estimated amount of funding that is planned for Food and Nutrition: Policy, Tools $20,000

and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.08:

Funding for Treatment: Adult Treatment (HTXS): $0

This PHE activity, "Identifying optimal models of HIV care and treatment in Mozambique", was approved for

inclusion in the COP. The PHE tracking ID associated with this activity is MZ.07.0079

Continuing activity from FY06 - activity number 5250.06

Columbia University will continue to conduct the PHE called "Identifying Optimal Models of HIV Care and

Treatment in Mozambique" (this study was entitled "Assessment of influence of quality of services on

clinical outcomes" in COP 2006) approved by local and Columbia University IRB in June 2007, and

expected to be concluded in June 09. The study will be submitted to CDC Atlanta IRB in Sept 2007. The

estimated costs are 50,000 USD. 54% of the total amount will be expended by February 2008. The local

coinvestigators

are: Dr Americo Assane, Chief of Department of Medical Assistance, Mozambican Ministry of

Health; Dr. Florindo Mudender, Department of Medical Assistance, Mozambican Ministry of Health. The

main objectives of the study are: 1) To assess the degree of variation in patient outcomes across HIV care

and treatment delivery sites, independent of the differences in patient-level characteristics across sites; 2)

To identify facility and program level characteristics that are associated with HIV care and treatment

outcomes, after adjusting for patient-level characteristics; 3) To assess the costs and clinical benefits of

modifying facility and program-level characteristics that appear to influence HIV care and treatment

outcomes and quality adjusted life years (QALYs). Secondary analysis of routinely collected patient data

combined with data from routine assessments of facility and program level characteristics will be used. This

work is vital to identifying important programmatic aspects of HIV care and treatment programs for use in

planning future programs and improving existing ones in Mozambique and elsewhere. Current status: the

first round of data collection is expected to start in October 2007. Findings will be shared with participants,

study sites and ICAP supported sites involved. It is also in the public interest that findings be made available

to a broader range of HI/AIDS health care providers. For FY08 is expected to continue the following rounds

of data collection. Budget justification: 1) Salaries: USD 22,400; 2) Equipment: USD 11,600; 3) Travel: USD

16,000. Total: USD 50,000>

Note: This evaluation in one of three PHEs that come from activity 5250.06. The total amount of funds for

these evaluations remain at USD 500,000, although individual studies have changed their initial budget

totals (in agreement with CDC GAP Mozambique).

New/Continuing Activity: Continuing Activity

Continuing Activity: 16278

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16278 16278.08 HHS/Centers for Columbia 7403 3568.08 Track 1 ARV $0

Disease Control & University Moz

Prevention Supplement

Table 3.3.09:

Funding for Treatment: Adult Treatment (HTXS): $0

This PHE activity, "Assessing the acceptability, effectiveness and cost benefit of two interventions to

improve long-term adherence to ART among adults receiving HIV care and treatment in Mozambique", was

approved for inclusion in the COP. The PHE tracking ID associated with this activity is MZ.07.0080.

Continuing activity from FY06 - Activity number 5250.06; FY08 Act. ID 16279

Columbia University will continue to conduct the PHE called "Assessing the acceptability, effectiveness and

cost benefit of two interventions to improve long-term adherence to ART among adults receiveing HIV care

and treatment in Mozambique" (it was designated as "Assessment of the effectiveness of peer-based

adherence support in maintaining and improved adherence to ART" in COP 06). The analysis regarding

cost effectiveness will conducted by CDC Atlanta. The protocol is in development and should be submitted

to Local, Columbia University and CDC Atlanta IRBs in October 2007. The estimated costs are USD

150,00. 54% of the total amount will be expended by February 2008. The local co-investigators are: Dr

Americo Assane Chief of Department of Medical Assistance, Mozambican Ministry of Health; Dr. Florindo

Mudender, Department of Medical Assistance, Mozambican Ministry of Health. The main objectives of the

study are to: 1) assess the effectiveness of two adherence support interventions, 2) identify factors

associated with sub-optimal adherence to ART at 3, 6, and 12 months after ART initiation, 3) estimate the

costs and clinics benefits and determine the acceptability of these two adherence support interventions.

Design: A two-pronged separate sample pre-post design will be used to assess the impact of a two

adherence support intervention. Both adherence interviews with patients enrolled in pre and

postinterventions

cohorts and data abstraction of routinely collected immunological and virological data for all

patients (i.e. those enrolled and not enrolled in the cohorts) before and after the intervention's

implementation will be conducted.This work is vital to identifying relevant programmatic enablers and

barriers for long term ART adherence in adults. Current status: the protocol is in final phase of development

and should be submitted to local, Columbia University and CDC Atlanta IRBs in October 2007. Findings will

be shared with participants, study sites and ICAP supported sites involved. It is also in the public interest

that findings be made available to a broader range of HIV/AIDS health care providers. Budget justification:

1) Salaries: USD 137,000; 2) Equipment: USD 4,000; 3) Travel: USD 6,000; 3) Office supplies: USD 3,000,

Total: USD 150,000

Note: This evaluation in one of three PHEs that come from activity 5250.06. The total amount of funds for

these evaluations remain at USD 500,000, although individual studies have changed their initial budget

totals (in agreement with CDC GAP Mozambique).

New/Continuing Activity: Continuing Activity

Continuing Activity: 16279

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16279 16279.08 HHS/Centers for Columbia 7403 3568.08 Track 1 ARV $0

Disease Control & University Moz

Prevention Supplement

Table 3.3.09:

Funding for Treatment: Adult Treatment (HTXS): $0

This PHE activity, "Establishment of sentinel cohorts of patients in HIV care and treatment services in

Mozambique", was approved for inclusion in the COP. The PHE tracking ID associated with this activity is

MZ.07.0081.

Continuing activity - FY06 Activity number 5250.06

Columbia University will continue to conduct the PHE called "Establishment of sentinel cohorts of patients in

HIV care and treatment services in Mozambique" (it was nominated as "Assessment of Viral load as a

predictor of therapeutic failure as compared to CD4 Count) and future clinical outcomes " in COP 06). At the

moment the protocol is under NY & in-country team revision. It should be submitted to Mozambican,

Columbia University and CDC Atlanta IRB in October 2007. The study is expected to be completed by

December 09. The estimated costs are 300,000 USD. 65% of the total amount will be expended by

February 2008. The local co-investigators are: Dr Americo Assane, Chief of Department of Medical

Assistance, Mozambican Ministry of Health; Ilesh Jani, Department of Immunology, National Institute of

Health. The main objective of the study is to characterize the clinical, immunologic and virologic

characteristics and keys short-term (early) program outcomes among adult (= 15y) and pediatric (<15y)

patients with confirmed HIV infection who are enrolled in HIV care and treatment programs in Mozambique.

It will be a multi-site, prospective cohort study. This work is vital to identifying important programmatic

aspects of HIV care and treatment programs for use in planning future programs and improving existing

ones in Mozambique and elsewhere. Current status: to be sent to local, Columbia University and CDC

Atlanta IRBs in October 2007. Findings will be shared with participants, study sites and ICAP supported

sites involved. It' is also in the public interest that findings be made available to a broader range of HI/AIDS

health care providers. For FY08 is expected to continue the next rounds of data collection. Budget

justification: 1) Personnel: USD 71,000; 2) Equipment: USD 4,000; 3) Travel: USD 10,000; 4) Supplies:

USD 215,000. Total: 300,000

Note: This evaluation in one of three PHEs that come from activity 5250.06. The total amount of funds for

these evaluations remain at USD 500,000, although individual studies have changed their initial budget

totals (in agreement with CDC GAP Mozambique).

New/Continuing Activity: Continuing Activity

Continuing Activity: 16281

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16281 16281.08 HHS/Centers for Columbia 7403 3568.08 Track 1 ARV $0

Disease Control & University Moz

Prevention Supplement

Table 3.3.09:

Funding for Treatment: Adult Treatment (HTXS): $5,546,101

April09 Reprogramming: Increased $1,273,019.

This is a continuing activity: Update to an existing narrative

This activity is a continuation of treatment activities that were initiated in FY04-7 as part of Columbia

University Track 1.0 supplemental funding. Funding will be used to continue supporting 30 ART sites

(including 3 military facilities and initiate support to 4 new ART facilities), as well as training of health

workers, technical assistance to the district and provincial and central level MOH and ensure quality of

services provided through continuous program monitoring and evaluation, site supervision and linkage with

Community Based Organizations. Funding during FY08 will be used for the recruitment of doctors,

counselors and nurses, and to support the provision of a broad range of technical services directly to

Provincial and District Health Authorities.

Support will be provided to pediatric treatment scale up at all CU supported ART sites as well as specifically

to the pediatric Day Hospitals in Maputo and Nampula Central hospitals. CU will support the logistics

required to undertake PCR using DBS at site level, train, mentor and provide supervision for staff in

pediatric HIV care and treatment, develop linkages to PMTCT, pediatric Counseling and testing services

and general health services for children to increase the number of children receiving HIV care and

treatment.

Additional activities that will be included with this funding are:

1) Develop sub- agreements to finance community organizations to implement patient follow up and provide

adherence support

2) Support establishment of "moonlight" ART Pilot site(s) to increase access to ARV treatment for

vulnerable populations (such as drug users and commercial sex workers), improving access and services

for these particular groups at selected sites in Maputo and Nacala (Nampula province).

This activity will be informed by results from a qualitative assessment (I-RARE) conducted in November

2007, providing information about needs and barriers to access for HIV counseling and testing, and ART for

HIV-infected high-risk-group populations. Community-based and CT activities that will contribute to

increased identification and referal of high-risk group members in need of services are described in other

parts of the plan. It will be of crucial importance for ART sites to be prepared and provide services that are

open and user-friendly from the perspective of this particular group.

3) Include funding for a Provincial Treatment Coordinator support for Inhambane Province - (includes office

costs, vehicle, fuel, maintenance, security, driver and recruitment of a Technical Advisor). This will allow

Columbia University/ICAP to provide province-wide support to the ART scale up in Inhambane, ensuring

provision of quality ART services as well as program reporting. Inhambane Province currently provides

approximately 5% of CU's total number of people enrolled on ART)

4) Follow up military personnel identified as HIV positive during the prevalence study and ensure they are

referred and enrolled into HIV/AIDS care and treatment services. This will include training nurses working at

military bases on follow up of patients receiving ART (under supervision of Military doctor), management of

opportunistic infections and treatment adherence.

5) Pilot a comprehensive HIV care and treatment program in the Civil Prison targeting men, women and

their children, guards, and their families. This intervention includes provision of HIV counseling and testing

(CT), risk reduction and behavior change interventions, PMTCT services for female inmates, screening and

treatment for Sexually Transmitted Diseases (STDs), TB and other Opportunistic Infections (OIs), and ART

services for eligible HIV-infected persons identified.

Once released from prison, HIV positive in-mates will be provided with referrals and assigned a case

manager to assure that they have been able to access care and treatment within the general community.

Funding to support this activity will be used to provide training for doctors, nurses and other health staff

working in the two selected pilot sites, as well as to ensure availability of necessary supplies; to support

program monitoring, a peer educator program and treatment support groups, disseminate IEC materials for

treatment literacy including PwP messages.

FY07:Follow up the military personnel identified as HIV positive during the prevalence study and make sure

they are all enrolled in HIV/AIDS treatment sites. Train nurses working at military bases on ART prescription

and identification of OIs. These nurses will be responsible to provide CT, collect the drugs for each ART

eligible soldier in his unit at the nearest treatment site, and assist them on how to take the drugs. To ensure

TB/HIV treatment adherence, they will be trained using already existing treatment adherence materials

including those being newly developed by Columbia University. The nurses will report to the military doctor

in each location.

Provincial TX Coordinator Support for Inhambane - office costs, vehicle, fuel, maintenance, security, driver

and Technical Advisor

New/Continuing Activity: Continuing Activity

Continuing Activity: 16276

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16276 16276.08 HHS/Centers for Columbia 7403 3568.08 Track 1 ARV $13,825,000

Disease Control & University Moz

Prevention Supplement

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $880,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Estimated amount of funding that is planned for Food and Nutrition: Policy, Tools $100,000

and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.09:

Funding for Care: Pediatric Care and Support (PDCS): $259,104

ICAP-MZ-Mozambique is committed to full and equitable access for HIV infected and exposed children into

HIV care and treatment services. Four main areas of specific pediatric focus have been identified for the

next year activities: 1) early identification of infected infants/children, 2) early initiation of treatment, 3)

quality of care delivery to children in care and 4) retention of patients into care and treatment.

At the end of June 2008 (PEPFAR report) ICAP supported Pediatric care and treatment at 40 sites in

Maputo City, Gaza Province, Inhambane Province, Nampula Province, and Zambezia Province including

two referral Hospitals for HIV infected children in Maputo and Nampula. Approximately 12,200 children were

enrolled in care and 3,000 are on ARVs (879- 30% in the age group 0-1y; 958-32% in the age group 2-4y;

1125- 38% in the age group 5-14y).

Of all patients enrolled at sites supported by ICAP-MZ approximately 8% are children. The target for next

year is to reach a proportion of 10% of children enrolled in care.

To achieve the target described above CU will continue to support HIV care and treatment services at the

two Pediatric ART reference Hospitals at Maputo and Nampula and at the other existing sites and will

expand pediatric services to 12 new more sites.

This support includes procurement of equipment, supplies and medication, support for strategic information

and local staff mentoring in management of pediatric HIV care and treatment by regular Clinical officer visits

and activities planned together with the Provincial directorate (DPS) in order to build capacity of the on site

Multidisciplinary team.

Training will also target Medical assistants according to MOH "task shifting" recommendations in order to

expand pediatric care to rural areas and health centres. Clinicians will offer regular mentoring of medical

assistants at sites and support the Provincial and District Health Directorate (DPS and DDS) to build

capacity in managing, planning and supervising the HIV Pediatric program linking HIV pediatric care to the

Mother and Child Health Provincial Program.

A Pediatric HIV Advisor will coordinate CU pediatric support for all CU-supported sites; two pediatricians will

support two focal provinces (Zambezia and Nampula) and four nurses will strengthen the link with the

PMTCT and MCH programs at provincial level.

Identification of infected children will be strengthened by implementation of routine Provider Initiated Testing

and Counseling offered to all children admitted in the Pediatric ward and accessing Pediatric care at any

entry point in 50% of the services CU is supporting (all central, provincial and rural hospital) according to the

MOH recommendations.

CU is also supporting Early Infant Diagnosis (EID) though PCR DBS in 16 PMTCT sites (Maputo city,

Inhambane, Nampula) and 20 HIV Clinic and infants follow up offering a minimum package of care (growth

and neurological development monitoring, CTX prophylaxis, OIs treatment, infant feeding counseling and

support,confirmatory test at 9-18 months).

EID program will be also supported by strengthening Lab capacity in managing PCR DBS samples/results,

supplies chain and distribution. Support to the Central Immunology Laboratory by a laboratory nurse

supporting the National EID logistics throughout the Country will continue and support to Provincial

Laboratories (Gaza, Inhambane, Nampula) will start. At provincial level, close supervision will be provided

by the lab advisor and cooperation between laboratory advisor, the provincial laboratory technician and the

provincial clinical advisor will be encouraged. A Lab M&E system, including computer supply, development

and training of an M&E package, will be implemented and continuously supervised by the Lab Advisor and

M&E advisor.

Retention of children into care and treatment services will be another main goal for year 2009, with a

particular focus on children not yet started on ARV treatment.

Activities to optimize adherence/retention in care include enhancing patient support by training MCH staff in

skills & quality of care with a focus on adherence monitoring & counseling, group management skills &

psychosocial support.

Follow up of children in care and on ARV will also be improve by strengthening Home based care activities

by creating partnership with local and international NGOs that are supporting peers-educators and home

based care activities.

CU will strengthen linkages between existing OVC care and support programs and clinical care.Working

through community-based organizations and other partners with programs targeting OVC and their families,

CU will ensure that OVC have access not only to HIV care and treatment as needed, but are also referred

to psychosocial support and food and economic assistance, where possible.

Efforts will also be done to asure provision of ITN, safe water and food support, through linkages with

comunity based organizations and other PEPFAR partners.

Advocacy at MOH level to focus on the children and adolescent age groups for the psychosocial component

of the HIV National program will continue and support in developing training curriculum and material on

pediatric/adolescent testing and counseling and disclosure will be provided.

Quality of care delivered to exposed infants followed up at CCR consultation will be supported by

strengthening the ongoing comprehensive strategy of linking PMTCT program and CCR services at the 36

existing sites (Maputo, Inhambane, Nampula) and at new 13 PMTCT/CCR sites (Zambezia and Gaza

Province).

Capacity building of existing staff and enrollment of new MCH nurses will be CU focus.

Strong linkages between CCR consultation and Pediatric HIV care & treatment services is critical to provide

more effective interventions for early diagnosed infants and start them on ARVs. CU will continue to

emphasize this comprehensive approach, building on MCH and PMTCT services, focusing on follow up of

exposed infants, offering care, early diagnosis tests and prompt referral to HIV Clinic.

Regular monitoring of quality of care delivery for children in care and on ARVs have been done for the main

Provincial and General Hospital supported by CU (Mavalane GH, Jose'Macamo GH, Military H, Inhambane

PH, Quelimane PH, Mocuba RH, Marrere GH, Xai Xai PH) implementing a Quality control tool, called

Activity Narrative: Pediatric Standard of Care (Ped SOC) adapted and adopted by the MOH. The regular implementation of

the tool together with MDT discussion of results, identification of obstacles and problem solving showed an

increase in quality care delivered to children and their families by that service. The plan for year 2009 is to

continue using the PED SOC at sites where is already well established and expand to 6 more sites (Gaza,

Zambezia, Inhambane) as a routine monitoring of the performance of the site in offering quality care to

children.

CU will continue to support monitoring and evaluation activities at sites and capacity will be created at DPS

and DDS level to monitor ongoing activities and results for the pediatric component of the program,

including regular evaluation of quality of service delivery (pediatric Standard Of Care and Pediatric HIV

QUAL).

New/Continuing Activity: Continuing Activity

Continuing Activity: 16283

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16283 5198.08 HHS/Centers for Columbia 7403 3568.08 Track 1 ARV $640,000

Disease Control & University Moz

Prevention Supplement

8566 5198.07 HHS/Centers for Columbia 4859 3567.07 UTAP $680,000

Disease Control & University

Prevention

5198 5198.06 HHS/Centers for Columbia 3567 3567.06 UTAP $380,000

Disease Control & University

Prevention

Emphasis Areas

Construction/Renovation

Health-related Wraparound Programs

* Child Survival Activities

* Malaria (PMI)

* Safe Motherhood

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $30,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Estimated amount of funding that is planned for Food and Nutrition: Policy, Tools $15,000

and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Estimated amount of funding that is planned for Water $6,000

Table 3.3.10:

Funding for Treatment: Pediatric Treatment (PDTX): $1,893,476

April09 Reprogramming: Increased $121,242.

This is a continuing activity.

ICAP-MZ-Mozambique is committed to full and equitable access for HIV infected children into HIV care and

treatment services.

Three main areas of specific pediatric focus have been identified for the next year activities: 1) early

initiation of treatment for infected infants and children, 2) quality of care delivery to children on ART and 3)

retention of patients into treatment.

At the end of June 2008 (PEPFAR report) ICAP supported Pediatric care and treatment at 40 sites in

Maputo City, Gaza Province, Inhambane Province, Nampula Province, and Zambezia Province including

two referral Hospitals for HIV infected children in Maputo and Nampula. Approximately 3,000 children are

on ARVs (879- 30% in the age group 0-1y; 958-32% in the age group 2-4y; 1125- 38% in the age group 5-

14y).

Of all patients on ART approximately 10% are children; the target for next year is to reach a proportion 11%

of children on ART.

To achieve the target described above CU will continue to support HIV care and treatment services at the

two Pediatric ART reference Hospitals at Maputo and Nampula and at the other existing sites and will

expand pediatric services to 12 new sites.

This support includes procurement of equipment, supplies and medication, support for strategic information

and local staff mentoring in management of pediatric HIV care and treatment by regular clinical officer visits

and activities planned together with the Provincial directorate (DPS) in order to build capacity of the on-site

multidisciplinary team.

Training will also target Medical assistants according to MOH "task shifting" recommendations in order to

expand pediatric care to rural areas and health centres. Training will focus on the new MOH/WHO

guidelines for initiation of children on treatment in order to decrease morbidity and mortality including WHO

new staging. Clinicians will offer regular mentoring of medical assistants at sites and support the Provincial

and District Health Directorate (DPS and DDS) to build capacity in managing, planning and supervising the

HIV Pediatric program linking HIV pediatric care to the Mother and Child Health Provincial Program.

A Pediatric HIV Advisor will coordinate CU pediatric support for all CU-supported sites; two pediatricians will

support two focal provinces (Zambezia and Nampula) and four nurses will strengthen the link with the

PMTCT and MCH programs at provincial level.

The plan is to strengthen EID at sites where it's already operational and expand it to 9 more sites continuing

training staff in collecting DNA via DBS.

Strong linkages between CCR consultation and Pediatric HIV care & treatment services is critical to provide

more effective interventions for infants early diagnosed and start them on ARVs. CU will continue to

emphasize this comprehensive approach, building on MCH and PMTCT services, focusing on follow up of

exposed infants, offering care, early diagnosis tests and prompt referral to HIV Clinic.

The referral system between the CCR and the ARV Clinic will be strengthened, especially for infected

infants that need early initiation according to new MOH and WHO guidelines, by up-dating staff on the new

guidelines and reinforcing the role of peer educator and activists in building this link. The expected

proportion of positive infants less than 12 months of age started on ART is 100% at all sites providing

ARVs; at the moment it varies from 15% to 50% depending on site and province.

Identification of infected children will be strengthened by implementation of routine Provider Initiated Testing

and Counseling (PICT) offered to all children admitted in the Pediatric ward and improve access to ART.

Regular monitoring of quality of care delivery for children on ARV have been done for the main Provincial

and General Hospital supported by CU (Mavalane GH, Jose Macamo GH, Military H, Inhambane PH,

Quelimane PH, Mocuba RH, Marrere GH, Xai Xai PH) implementing a Quality control tool, called Pediatric

Standard of Care (Ped SOC) adapted and adopted by the MOH. The regular implementation of the tool

together with Multi-disciplinary Team (MDT) discussion of results, identification of obstacles and problem

solving showed an increase in quality care delivered to children and their families by that service. The plan

for year 2009 is to continue using the PED SOC at sites where is already well established and expand to 6

more sites (Gaza, Zambezia, Inhambane) as a routine monitoring of the performance of the site in offering

quality care to children.

CU will continue to support monitoring and evaluation activities at sites and capacity will be created at DPS

and DDS level to monitor ongoing activities and results for the pediatric component of the program,

including regular evaluation of quality of service delivery (Pediatric Standard Of Care and Pediatric HIV

QUAL).

The overall retention of patients into ART care is around 85%, but more specific date on the pediatric

population are needed.

Retention of children into care and treatment services will be another main goal for year 2009; activities to

optimize adherence/retention in care include enhancing patient support by training MCH staff in skills &

quality of care with a focus on adherence monitoring & counseling, group management skills & psychosocial

support.

Follow up of children on ARV will also be improve by strengthening Home-based care activities by creating

partnership with local and international NGOs that are supporting peer educators and home based care

activities.

Advocacy at MOH level to focus on the children and adolescent age groups for the psychosocial component

of the HIV National program will continue and support in developing training curriculum and material on

pediatric disclosure will be provided.

New/Continuing Activity: Continuing Activity

Continuing Activity: 16276

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16276 16276.08 HHS/Centers for Columbia 7403 3568.08 Track 1 ARV $13,825,000

Disease Control & University Moz

Prevention Supplement

Table 3.3.11:

Funding for Care: TB/HIV (HVTB): $785,792

Continuing Activity:

All PEPFAR clinical partners will support core TB/HIV collaborative activities in accordance with the WHO

Interim Policy (2004) in all districts and facilities that are supported for other clinical activities. This includes

(1) active participation in TB/HIV coordinating mechanisms at national, provincial, and local level, supporting

MOH TB/HIV planning and supervisory activities, and assisting with TB/HIV monitoring and evaluation

activities. In addition, clinical partners assist national TB programs with activities to reduce the burden of

TB in HIV-infected persons under their care through comprehensive and routine TB screening, isoniazid

preventive therapy (IPT) for those without symptoms or contraindications, and facility-level infection control

measures. Finally, all clinical partners support activities by the TB program to reduce the burden of HIV

through provider-initiated counseling and testing (PICT) for all TB patients (including children),

cotrimoxazole preventive therapy (CPT) (provided in TB clinics) for all TB patients, and referrals or on-site

provision of ART to coinfected patients. In accordance with new WHO guidance and with experience in

Mozambique that some activities (e.g. HIV-testing, CPT and ART) have advanced faster than others, all

partners will be encouraged to strengthen activities related to the 3 I's: intensified TB case finding, IPT, and

infection control. This includes support for routine (and WHO and NTP-recommended) contact tracing.

Partner-specific activities are described below.

At Columbia university- supported sites the Columbia university- staff has been working to provide a

package of TB/HIV integrated activities according who recommended TB/HIV collaborative activities, the

Mozambican MOH recommendations and Mozambican TB strategic plan.

Columbia university will continue to implement TB/HIV collaborative activities and to emphasize the

implementation of the "three I's": intensified case finding (ICF), Isoniazid prophylaxis (IPT) and infection

control (IC). Although the implementation of the "three I's" should be owned by HIV program, there is a

need to strengthen the TB treatment sites support where the implementing partners are working.

Columbia University will continue to support provider-initiated HIV counseling and testing for TB patients

who arrive at the TB clinics linked to art clinic with unknown HIV status, expanding it also at other peripheral

TB units and strengthen referral system with ART clinics.

This will include provincial refresh training on HIV counseling & testing for TB nurses, supervision &

mentoring, implementation of M&E and referral systems, TB/HIV staff, supplies and equipments.

Columbia university will strengthen TB intensified case finding among HIV patients enrolled in ART

supported facilities -through the TB screening tool developed by ICAP and recently adopted by the national

TB program - as well as the referral system of co-infected patients and comprehensive care and follow-up of

co-infected patients. The use of the TB screening tool will be improved in terms of regularity of its use, the

way of patient's information is recorded, quality of diagnostic process, timeless and completeness.

This will be through training staff, continuous supervision/mentoring, strengthening of the M&E systems,

TB/HIV staff, supplies and equipments.

Provincial update training on clinical management of TB/HIV for clinical staff, including clinical officers

("técnicos de medicina") will be organized.

Furthermore Columbia University will expand TB active case finding in pediatric HIV patients through the

implementation of the adopted WHO "guidance for national tuberculosis programmes in the management of

tuberculosis in children", training and technical assistance.

Both the TB program and the HIV program should be an entry point for the prompt identification and the

best possible case-management of co-infected patients.

Columbia University has been promoting functional and scalable linkages and referral systems between TB

and HIV services for patients with known or suspected co-infection.

Cotrimoxazole prophylaxis is provided for co-infected patients at both TB and HIV services and CU will

promote its correct and regular implementation at supported sites.

TB prevention and infection control also will be promoted at supported facilities through promotion of IPT for

eligible HIV patients and through administrative-personal- environment basic measures to reduce the risk of

TB infection transmission.

IPT is recommended and promoted by the national TB program but is not regularly and completely

implemented yet. This is due to the clinicians' concern in selecting eligible patients and in ensuring their

regular follow up.

Moreover, national stock out of Isoniazid led to a delay in the implementation of the activity nationwide.

At Columbia university-supported facilities IPT has been progressively implemented and it will be expanded

and strengthened through training staff, continuous supervision/mentoring, strategies to truck patients and

improve their adherence and follow up.

At national level CU has been collaborating with the national TB program and the national TB/HIV Task

Force through technical assistance, regular participation to the meetings, review of guidelines and manuals,

development of tools and forms.

Support and technical assistance at national level will be continued as well as logistical support for revising,

translating and reproducing manuals, tools and any instruments for TB/HIV integration (that includes a

"pocket guide"on TB/HIV collaborative activities based on the national recommendations) and regular

participation to meetings of the TB/HIV Task Force to enhance partnerships and coordination of TB/HIV

activities.

Support health system strengthening and collaboration between programs from national level to service

delivery level will be offered through:

- Support provincial health directorates in organizing provincial meetings on TB/HIV integration for TB staff

and HIV representative staff from all the districts;

- support integrated supervision of TB/HIV activities and DOTS at provincial and district level;

- support regional training on TB program management for key TB staff;

- close collaboration of CU staff and the provincial and district health directorates

New/Continuing Activity: Continuing Activity

Continuing Activity: 16282

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16282 5201.08 HHS/Centers for Columbia 7403 3568.08 Track 1 ARV $875,000

Disease Control & University Moz

Prevention Supplement

8565 5201.07 HHS/Centers for Columbia 4878 3568.07 Track 1 ARV $1,100,000

Disease Control & University Moz

Prevention Supplement

5201 5201.06 HHS/Centers for Columbia 3567 3567.06 UTAP $563,000

Disease Control & University

Prevention

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $195,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.12:

Funding for Testing: HIV Testing and Counseling (HVCT): $923,800

Continuing Activity:

To date Columbia University (CU) has supported HIV Care and Treatment in districts in Zambezia, Nampula

and Gaza Provinces as well as in Maputo City. CU provides supervision, clinical mentoring, and technical

assistance to include training, infrastructure development, capacity building to Provincial Health Directorates

(DPS). For FY09 PEPFAR Mozambique team has undergone a clinical partner rationalization exercise in

order to streamline support to cover all clinical services in a whole district by one clinical care partner. For

FY09 CU will receive budget allocations to cover facility based counseling and testing interventions -

Provider Initiated Counseling and Testing and CT in Health. CU will assume and continue CT services in

sites supported to other USG partners and include PICT in all sites where treatment is being implemented.

CU will continue to support activities related to C&T and disclosure for children in partnership with CDC and

Mozambican Ministry of Health and provider initiative counseling and testing (PICT) strategy. For the COP

09 CU will finalize training material, and will support national TOT and provincial trainings.

As a new programatic area CU will hire one C&T technical advisor to be based in Maputo headquarter to

oversee all C&T activities and operationalize a national plan that includes PICT and VCT according to MoH

guidance. To achieve its goals CU will take advantage of its adherence and psycho social support staff

already based in the provinces (Maputo City, Gaza, Inhambane, Zambezia and Nampula Province), and

peer educators groups, support groups and health providers in a comprehensive package of psycho social

support. The pshycho social structure already existing will serve as a backbone of counseling and testing

related activities in all CU supported districts.

CU will use subagreements established with Pathfinder International and TDB NGO with Track 1.0 funds to

identify and refer to C&T household/family members and potential new HIV infected individuals.

Aiming the objectives of the transition plan CU designed a plan to take over (including human resources,

technical assistance, training and supervision on a monthly bases) the exisiting VCT according to the

following plan:

1. first quarter - 8 sites

2. second quarter - plus 10 sites

3. third quarter - plus 13 sites

4. fourth quarter - plus 15 sites

In addition to that, CU will enhance providers skills to conduct PICT in 4 CU supported sites, in special for

pediatric and adults wards/outpatients units through mentorship system in Nampula and Maputo City or

Zambezia Province. Anticipated components of the mentorship system will include assessing each site's

set up for PITC implementation and supply chain management and interacting with the trained and

untrained PITC health care workers in different departments where PITC is being implemented. Mentorship

will also involve observation of pretest information and post test counseling sessions guided by a checklist,

mentoring of specified skills especially on testing and counseling procedures and observing procedures in

conducting HIV testing using national testing algorithm. The final area of emphasis will be ensuring that

quality PITC data is recorded properly in HIV testing and counseling registers."

New/Continuing Activity: Continuing Activity

Continuing Activity: 16274

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16274 16274.08 HHS/Centers for Columbia 7403 3568.08 Track 1 ARV $80,000

Disease Control & University Moz

Prevention Supplement

Table 3.3.14:

Funding for Laboratory Infrastructure (HLAB): $340,000

THIS IS A NEW ACTIVITY

Laboratory services are an integral service component to support optimal care and treatment to HIV

patients. Columbia University (ICAP) has standardized laboratory services in different sites throughout the

Provinces in which we work. The main activity in the area of lab strengthening has been to assess

adequacy of laboratory sites and to adjust working environments to optimize laboratory services and

practices within available resources. This has included laboratory renovations in some districts to ensure

that laboratory infrastructure was such that new equipment, provided by APHL, could be placed.

ACTIVITIES AND EXPECTED RESULTS

Treatment Program Lab Advisor: The laboratory Technical Advisor based at the ICAP National Office level

will be responsible for overseeing the laboratory component of the PMTCT and Care and Treatment

Program within the ICAP supported districts and supporting ICAP staff in providing supervision of laboratory

services within the program. In addition, (s)he will function as a counterpart for the Laboratory Technical

Advisor based in DPS of each province.

The Laboratory Advisor will liaise and coordinate activities related to laboratory services with NGO's and

partners assisting the MOH in laboratory issues such as Clinton Foundation, SCMS, and APHL. The

Laboratory Advisor will identify weaknesses in laboratory processes, procedures, and logistics, propose

adequate strategies for improvement, and contribute to a plan towards building capacities at national,

provincial and district levels. He will give specific attention to realities and problems emanating from field

level, communicate needs and priorities identified and channel solutions to adequate forum and authorities.

The work of the laboratory advisor shall be integrated with on-going or new MOH national and provincial

laboratory activities and policies. (S)He shall also respond to priorities identified by ICAP teams or other

direct implementers in the Province. Overall, the ICAP Laboratory Technical Advisor will improve laboratory

services as a crucial component of quality care in the provinces supported by ICAP.

Provincial Lab Advisors: The MOH has requested that USG Partners support 4 technical advisor positions

within the Provincial Directorate for Health Offices (DPS) each of the 11 Provinces. One of these technical

advisors is a Laboratory Technical Advisor. As lead Clinical Partner in three Provinces, ICAP will support

salary and benefits for three of the Provincial lab technical advisors. Provincial Lab Technical Advisors will

report directly to the DPS and will oversee laboratory activities across the Province, irrespective of what, if

any, partner support is given. The Provincial level Lab Tech Advisors will create a link between the central

level Laboratory Section and the Province to facilitate communication and information flow and to implement

policies and practices established by central level MOH. Advisors will work with implementing partners,

DPS, and other donors to strengthen laboratory commodity logistics, quality assurance, monitoring and

evaluation of lab services, and human capacity development.

Total Budget: $340,000 (85,000 each for 4 technical advisors)

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $170,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.16:

Funding for Strategic Information (HVSI): $129,111

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

This is a new activity in that it is organized as its own separate activity, but is a continuation of the

subactivity listed as Activity 8639.08 in COP 08 (Provincial M&E Officers).

This is related to the following activities in COP 09:

Ministry of Health has placed increasing focus on strengthening human and technical resources at the

provincial level to improve the coordination and delivery of services in the province. In FY08, Ministry of

Health developed a standard set of technical advisor positions to be placed at the Provincial level; these

four positions included advisors in Clinical Care, Laboratory, Pharmacy, and Monitoring and Evaluation.

USG was asked to assist with the funding and recruitment of these positions at the provincial level. The

primary partner responsible for providing technical assistance in the area of clinical services in a province

will also be responsible for the recruitment and support of the four technical advisor positions, including this

Monitoring and Evaluation Technical Advisor position.

The M&E Provincial Advisor will provide support in the cooridnation of routine activities related to monitoring

and evaluation at the Provincial Directorate of Health, giving priority to endemic diseases, including HIV.

This advisor will help to reinforce adn support the implementation of the decentralization of HIV services

including related data collection systems. S/he will provide leadership in the supervision and management

of data to ensure the quality of data at the district and site level, help to strengthen the flow of data to the

district, provincial, and central levels. Additionally this person will support the Provincial Directorate of

Health in the analysis and dissemination of data (for example, to the site level, Ministry of Health, and

partners.) This person will sit within the Provincial Department of Planning and Cooperation at the

Provincial Directorate of Health.

Columbia University/ICAP has been asked to place 3 M&E Advisor in Maputo City, Nampula, and

Inhambane as part of their overall support to clinical services in these Provinces.

New/Continuing Activity: New Activity

Continuing Activity:

Table 3.3.17:

Funding for Strategic Information (HVSI): $150,000

THIS IS A NEW ACTIVITY

The Ministry of Health uses an MS Access-based database (Modulo Basico) to collect, manage, and report

routine (monthly) aggregate facility level information at the provincial and national level. This program was

developed for Mozambique by an expatriate programmer in 2004 and has been supported by the

programmer who is seconded to the Ministry of Health's Department of Health Information since then. This

position has been supported by funds from another donor, but these funds are being discontinued. USG

has agreed to provide salary support for the continuation of this position, which is being competed in

October 2008, to ensure continued basic support of this critical system.

A key focus of this technical advisor is capacity building and systems strengthening within the Department

of Health Information. The advisor will actively participate in the training of his Mozambican counterparts, at

all levels of the Health System of the Republic of Mozambique and will assist with the integration of National

Health Information System with other diverse vertical programs.

Discussions are in progress with the Ministry of Health to identify a specific individual to work on modulo

basico. Mentorship of this Mozambican counterpart would be a prioirity for PEPFAR Mozambique.

This advisor will participate in a different but related activity (currently funded with existing funds through I-

TECH) to develop recommendations for modifications and enhancements to the Modulo Basico system. It

is expected that this advisor would play a key role helping to prioritize enhancements that are needed in the

system as well as to participate in the implementation of these enhancements.

New/Continuing Activity: New Activity

Continuing Activity:

Table 3.3.17:

Funding for Strategic Information (HVSI): $150,000

THIS IS A NEW ACTIVITY

This is listed as a new activity in COP 09 but was funded in previous COPs under a different program area.

The Ministry of Health's Department of Health Information (DIS) is responsible for the overall coordination

and strengthening of health information systems in the Ministry of Health. Currently, DIS faces a dire

shortage of human resources in terms of number of qualified staff needed to carry out key tasks. Since

2007, CDC has funded a technical advisor secunded to the MOH's DIS to assist with strategic planning and

implementation of key activities in the DIS annual workplan.

A key focus of this technical advisor is capacity building and systems strengthening within the Department

of Health Information. The advisor will actively participate in the training of Mozambican counterparts, at all

levels of the Health System of the Republic of Mozambique and will assist with the integration of National

Health Information System with other diverse vertical programs.

New/Continuing Activity: New Activity

Continuing Activity:

Table 3.3.17:

Funding for Health Systems Strengthening (OHSS): $1,919,449

April09 Reprogramming: Increased $331,465.

This is a new activity.

This activity will contribute to strengthening health system at the provincial level with the goal of developing

a more sustainable health care system.

The Ministry of Health is vitally interested in developing a cadre of technical advisors, preferably

Mozambicans, where possible. The USG shares this goal and will be working with all treatment partners to

develop ways of preparing Mozambicans for these positions such as on-the-job mentoring and education. 4

Pharmacy advisors will be hired by Columbia University will support Provincial and District Health

Directorates to create capacity in the area of drugs and consumables. Advisors will work closely with DPS

parmacy technicians, warehouses incharges and HIV/TB/Malaria coordinators in order to avoid stock outs

and to reinforce the links between facilities, provincial and central level. Emhasis will be put on forecasting

capacity.

:In COP09 will for the first time treat infrastructure development as a discrete rather than embedded

program area, with appropriate budgetary provision, and a program structure designed to improve the

speed, quality, and cost effectiveness of implementation. Two mechanisms will be employed to deal with

large- and medium-scale construction. Treatment partners will be relieved of the burden of having to

manage activities that are somewhat removed from their primary fields of excellence. However there will

still be cases where it is more efficient and appropriate for these partners to organize minor building repairs

and improvements locally rather than through a central mechanism. CU will support minor renovations of

pharmacy areas at new facilities where the assessment will show the need.

CU plans funds to support salary for freshly graduated professionals to cover the period between end of

studies and the entry in the National Health Service. Provinces where CU will be the lead partner will be

prioritized for this activity and this will anyway be done according to the needs and requests of MoH. It is

expected that this gap year funding will retain graduates at their work while the national health services and

other ministeries finalize their recruitment process to become those new health workers as public servants

integrated in the national health services. An estimate of 15-20 professionals could be supported through

this activity. In calendar year 2009, it is anticipated that the MOH will institute salary reform and therefore

raise salaries so the number of staff supported may change.

Given the urgent need for increasing the number health care workers at all levels, PEPFAR funds will be

used to pay for course fees associated with attending a pre-service institution. The goal of this activity is to

both increase the production of health care workers and lessen the numbers who drop out due to financial

constraints. CU will support about sixty students for the course of Health Technician and Nurse in Nampula

Province at Instituto de Ciencias da Saude. The planned amount of 200,000 USD will cover the first 12

months of the courses for a total of 90 students.

CU will offer Counseling module (ATS and Adhrence) for pre-service training to health technician, basic

nurse and preventive medicine technician (30 health tecnicians and 30 nurses) at Instituto de Ciências da

Saúde da Zambézia

CU will work with districts to health managment teams to build on planning and managment capacity.

CU will support coordination activities at District level with the aim of widening the support from site to

district support. This activity will have particular emphasis in Provinces were CU will be the lead partner

(about 20 districts). This will include a broad range of activities like technical and financial support for

integrated supervisions, planning exercises, managment meetings and district health information systems.

Products/deliverables

It is expected to have 30 professionals trained in CT.

90 students will be supported for the first year the three courses for Health technician and Nurses.

10 Health facilities will receive rehabilitation according to DPS priorities for a total amount of 450,000 USD

15-20 professional receive salary up to 12 months

4 Pharmacy Technical Advisor for Provincial Health Directorate hired

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $1,097,984

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Estimated amount of funding that is planned for Education $300,000

Water

Table 3.3.18:

Subpartners Total: $1,549,000
Pathfinder International: $850,000
Mothers2mothers: $150,000
Zambezia Provincial Health Directorate: $99,000
Delgado Health Secretariat: $196,000
Ministry of National Defense: $190,000
Delgado Health Secretariat: $64,000
Cross Cutting Budget Categories and Known Amounts Total: $3,263,984
Public Health Evaluation $0
Food and Nutrition: Policy, Tools, and Service Delivery $300,000
Food and Nutrition: Commodities $75,000
Human Resources for Health $75,000
Food and Nutrition: Policy, Tools, and Service Delivery $20,000
Human Resources for Health $880,000
Food and Nutrition: Policy, Tools, and Service Delivery $100,000
Human Resources for Health $30,000
Food and Nutrition: Policy, Tools, and Service Delivery $15,000
Water $6,000
Human Resources for Health $195,000
Human Resources for Health $170,000
Human Resources for Health $1,097,984
Education $300,000