Detailed Mechanism Funding and Narrative

Years of mechanism: 2008 2009

Details for Mechanism ID: 483
Country/Region: Kenya
Year: 2009
Main Partner: University of Washington
Main Partner Program: NA
Organizational Type: University
Funding Agency: HHS/CDC
Total Funding: $4,614,213

Funding for Care: Adult Care and Support (HBHC): $467,698

This PHE activity, "Impact of Cryotherapy versus Loop Electrosurgical Excision Procedure (LEEP) on

Recurrence of Cervical Intraepithelial Neoplasia and HIV-1 Cervical Shedding among HIV-positive Women"

was approved for inclusion in the COP. The PHE tracking ID associated with this activity is KE.09.0238.

This PHE is NEW in COP 09.

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Human Capacity Development

Public Health Evaluation

Estimated amount of funding that is planned for Public Health Evaluation $467,698

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.08:

Funding for Care: Adult Care and Support (HBHC): $426,515

This PHE activity, "Empiric therapy of helminth co-infection to reduce HIV-1 disease progression," was

approved for inclusion in the COP. The PHE tracking ID associated with this activity is KE.07.0039. A copy

of the progress report is included in the Supporting Documents section.

New/Continuing Activity: Continuing Activity

Continuing Activity: 17845

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

17845 17845.08 HHS/Centers for University of 7020 483.08 $160,000

Disease Control & Washington

Prevention

Emphasis Areas

Human Capacity Development

Public Health Evaluation

Estimated amount of funding that is planned for Public Health Evaluation $426,515

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.08:

Funding for Care: Adult Care and Support (HBHC): $370,000

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS FROM COP 2008:

+ New activity emphasis on prevention with positives among patients coming for care and treatment

services.

COP 2008

1. LIST OF RELATED ACTIVITIES

This activity relates to activities in TB/HIV, Pediatric ARV services, Pediatric Care and Support, Prevention,

and ARV Services.

2. ACTIVITY DESCRIPTION

The University of Washington (UW) will expand a long standing research collaboration with the University of

Nairobi to provide HIV care to 7,000 people with advanced HIV at 3 care sites, and support the training of

30 individuals in the provision of HIV-related palliative care services. UW will support treatment services at

Coptic Hospital, a faith-based facility in Nairobi that provides services to both the general population and

individuals identified through research programs at the University of Nairobi. In addition, UW will support

treatment services to two "daughter" clinics (clinics supported by the Coptic Church at facilities in Nyanza

Province and in the industrial area of Nairobi). Other important aspects of the UW/Coptic Hospital program

support behavior change and risk reduction for people with HIV/AIDS, with specific emphasis on patients

with less advanced HIV, in whom rates of discordant partnerships have been found to be high and also

Positive Prevention. Funds will be used to support salaries of health care providers in accordance with

Emergency Plan guidance, logistics (primarily pharmacy management), dissemination of informational

materials (about ARVs and adherence) to patients, and procurement of commodities such as laboratory

reagents. This partner will maintain data concerning the numbers of clients served and will report this

information both nationally and through the Emergency Plan.

UW has a long presence in Kenya and extensive experience in HIV prevention and treatment both in the

United States (U.S.) and internationally. The University has a long standing research collaboration with the

University of Nairobi and has provided extensive capacity building in immunology and epidemiology,

including supporting long-term training for University of Nairobi staff in the U.S. University of Nairobi staff

have also donated their time to support the establishment of HIV care services at Coptic Hospital.

3. CONTRIBUTIONS TO OVERALL PROGRAM AREA

These activities will contribute to expansion of access to palliative care services for people with HIV,

strengthened human resource capacity to deliver care services, and an improved referral network for

provision of these services.

4. LINKS TO OTHER ACTIVITIES

These services will link closely to adult ARV treatment services provided at Coptic Hospital, Pediatric care

and support, Pediatric ARV services, TB/HIV services and also link directly to the Nairobi network center at

Kenyatta National Hospital and to other services provided through the expanding partnerships between

other US-based Universities and the University of Nairobi.

5. POPULATIONS BEING TARGETED

These programs target adults living with HIV/AIDS.

6. KEY LEGISLATIVE ISSUES ADDRESSED

This activity addresses legislative issues related to stigma and discrimination through community.

7. EMPHASIS AREAS

This activity includes minor emphases in commodity procurement, development of network/linkages/referral,

human resources, information, education, and communication, local organization capacity building, logistics,

strategic information, training, and quality assurance and supportive supervision.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15036

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15036 4231.08 HHS/Centers for University of 7020 483.08 $549,769

Disease Control & Washington

Prevention

7099 4231.07 HHS/Centers for University of 4301 483.07 $200,000

Disease Control & Washington

Prevention

4231 4231.06 HHS/Centers for University of 3253 483.06 $100,000

Disease Control & Washington

Prevention

Table 3.3.08:

Funding for Treatment: Adult Treatment (HTXS): $2,750,000

ACTIVITY UNCHANGED FROM COP 2008

1. LIST OF RELATED ACTIVITIES

This activity relates to activities in Palliative Care: HBHC, PDCS, TB/HIV, Counseling and Testing and

PMTCT.

2. ACTIVITY DESCRIPTION

University of Washington (UW) will expand a long-standing research collaboration with the University of

Nairobi to provide HIV care, including antiretroviral therapy to 8,600 adults with advanced HIV (3,000 new),

bringing the total ever treated to 10,320. UW will support treatment services at Coptic Hospital, a faith-

based facility in Nairobi that provides services to both the general population and to individuals identified

through research programs at the University of Nairobi. Funding will also support the training of 30

individuals. In addition, UW will support treatment services to two "daughter" clinics (clinics supported by the

Coptic Church at facilities in Nyanza Province and in the industrial area of Nairobi). Other important aspects

of the UW/Coptic Hospital program support behavior change and risk reduction for people with HIV/AIDS,

with specific emphasis on patients with less advanced HIV, in whom rates of discordant partnerships have

been found to be high. Funds will be used to support salaries of health care providers in accordance with

Emergency Plan guidance, logistics (primarily pharmacy management), dissemination of informational

materials (about ARVs and adherence) to patients, and procurement of commodities such as laboratory

reagents. This partner will maintain data concerning the numbers of clients served and will report this

information both nationally and through the Emergency Plan. UW has an established presence in Kenya

and extensive experience in HIV prevention and treatment both in the United States and internationally. The

University has long-standing research collaboration with the University of Nairobi, and has provided

extensive capacity building in immunology and epidemiology, including supporting long-term training for

University of Nairobi staff in the United States. University of Nairobi staff has also donated their time to

support the establishment of care services at Coptic Hospital.

3. CONTRIBUTIONS TO OVERALL PROGRAM AREA

These activities will contribute to the results of expansion of ARV treatment for clinically qualified HIV-

positive patients, strengthen human resource capacity to deliver adult ARV treatment, tighten linkages

between prevention, care, and treatment activities, and strengthen referral networks for AIDS services.

4. LINKS TO OTHER ACTIVITIES

This activity relates to testing and treatment activities at the Nairobi network center at Kenyatta National

Hospital currently supported by and University of Nairobi, and to other services provided through the

expanding treatment partnerships between other US-based universities such as University of Manitoba,

University of California at San Francisco, and the University of Nairobi.

5. POPULATIONS BEING TARGETED

These programs target adults living with HIV. Included among the populations served by these services will

be participants in US government funded research programs.

6. KEY LEGISLATIVE ISSUES ADDRESSED

This activity addresses legislative issues related to stigma and discrimination through community.

7. EMPHASIS AREAS

This activity includes minor emphases in commodity procurement, development of network/links/referral

systems, human resources, local organization capacity building, logistics, information, education, and

communication, and quality assurance and supportive supervision, targeted evaluation, and training.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15039

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15039 4232.08 HHS/Centers for University of 7020 483.08 $3,100,000

Disease Control & Washington

Prevention

7100 4232.07 HHS/Centers for University of 4301 483.07 $2,883,938

Disease Control & Washington

Prevention

4232 4232.06 HHS/Centers for University of 3253 483.06 $1,270,000

Disease Control & Washington

Prevention

Table 3.3.09:

Funding for Care: Pediatric Care and Support (PDCS): $60,000

ACTIVITY UNCHANGED FROM COP 2008:

1. LIST OF RELATED ACTIVITIES

This activity relates to activities in TB/HIV (#8830), Adult Care and Support, ARV Services (#7100),

Pediatric ARV Services, and PMTCT.

2. ACTIVITY DESCRIPTION

University of Washington (UW) will expand long-standing research collaboration with the University of

Nairobi to provide HIV care to 1,000 children at 3 care sites, and support the training of 30 individuals in the

provision of HIV-related palliative care services. UW will support treatment services at Coptic Hospital, a

faith-based facility in Nairobi that provides services to both the general population and to individuals

identified through research programs at the University of Nairobi. In addition, UW will support treatment

services to two "daughter" clinics (clinics supported by the Coptic Church at facilities in Nyanza Province

and in the industrial area of Nairobi. Other important aspects of the UW/Coptic Hospital program support

behavior change and risk reduction for people with HIV/AIDS, with specific emphasis on patients with less

advanced HIV, in whom rates of discordant partnerships have been found to be high. Funds will be used to

support salaries of health care providers in accordance with Emergency Plan guidance, logistics (primarily

pharmacy management), dissemination of informational materials (about ARVs and adherence) to patients,

and procurement of commodities such as laboratory reagents. This partner will maintain data concerning

the numbers of clients served and will report this information both nationally and through the Emergency

Plan. UW has a long presence in Kenya and extensive experience in HIV prevention and treatment both in

the United States and internationally. The University has a long standing research collaboration with the

University of Nairobi, and has provided extensive capacity building in immunology and epidemiology,

including supporting long-term training for University of Nairobi staff in the United States. University of

Nairobi staff has also donated their time to support the establishment of HIV care services at Coptic

Hospital.

3. CONTRIBUTIONS TO OVERALL PROGRAM AREA

These activities will contribute to expansion of access to palliative care services for people with HIV,

strengthened human resource capacity to deliver care services, and a strengthened referral network for

provision of these services.

4. LINKS TO OTHER ACTIVITIES

These services will link closely to ARV treatment services provided at Coptic Hospital (#7100), Palliate

Care: TB/HIV services (#8830) and also link directly to the Nairobi network center at Kenyatta National

Hospital and to other services provided through the expanding partnerships between other US-based

Universities and the University of Nairobi.

5. POPULATIONS BEING TARGETED

These programs target children living with HIV/AIDS including infants (0 - 5 years) and children (6 - 14

years).

6. KEY LEGISLATIVE ISSUES ADDRESSED

This activity addresses legislative issues related to stigma and discrimination through community.

7. EMPHASIS AREAS

This activity includes minor emphases in commodity procurement, development of network/linkages/referral,

human resources, information, education, and communication, local organization capacity building, logistics,

strategic information, training, and quality assurance and supportive supervision.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15036

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15036 4231.08 HHS/Centers for University of 7020 483.08 $549,769

Disease Control & Washington

Prevention

7099 4231.07 HHS/Centers for University of 4301 483.07 $200,000

Disease Control & Washington

Prevention

4231 4231.06 HHS/Centers for University of 3253 483.06 $100,000

Disease Control & Washington

Prevention

Table 3.3.10:

Funding for Treatment: Pediatric Treatment (PDTX): $310,000

ACTIVITY UNCHANGED FROM COP 2008:

1. LIST OF RELATED ACTIVITIES

This activity relates to activities in Palliative Care: TB/HIV (#8830) and Palliative Care: Basic Health Care

and Support (#7099)

2. ACTIVITY DESCRIPTION

The University of Washington (UW) will expand a long standing research collaboration with the University of

Nairobi to provide HIV care, including antiretroviral therapy to 800 children with advanced HIV (500 new),

bringing the total ever treated to 960. UW will support treatment services at Coptic Hospital, a faith-based

facility in Nairobi that provides services to both the general population and to individuals identified through

research programs at the University of Nairobi. In addition, UW will support treatment services to two

"daughter" clinics (clinics supported by the Coptic Church at facilities in Nyanza Province and in the

industrial area of Nairobi. Funding will also support the training of 30 individuals. Other important aspects of

the UW/Coptic Hospital program support behavior change and risk reduction for people with HIV/AIDS, with

specific emphasis on patients with less advanced HIV, in whom rates of discordant partnerships have been

found to be high. Funds will be used to support salaries of health care providers in accordance with

Emergency Plan guidance, logistics (primarily pharmacy management), dissemination of informational

materials (about ARVs and adherence) to patients, and procurement of commodities such as laboratory

reagents. This partner will maintain data concerning the numbers of clients served and will report this

information both nationally and through the Emergency Plan. UW has an established presence in Kenya

and extensive experience in HIV prevention and treatment both in the United States and internationally. The

University has long-standing research collaboration with the University of Nairobi, and has provided

extensive capacity building in immunology and epidemiology, including supporting long-term training for

University of Nairobi staff in the United States. University of Nairobi staff have also donated their time to

support the establishment of care services at Coptic Hospital.

3. CONTRIBUTIONS TO OVERALL PROGRAM AREA

These activities will contribute to the results of expansion of ARV treatment for clinically qualified HIV-

positive patients, strengthen human resource capacity to deliver pediatric ARV treatment, tighten linkages

between prevention, care, and treatment activities, and strengthen referral networks for AIDS services.

4. LINKS TO OTHER ACTIVITIES

This activity relates to testing and treatment activities at the Nairobi network center at Kenyatta National

Hospital currently supported by and University of Nairobi, and to other services provided through the

expanding treatment partnerships between other US-based universities such as University of Manitoba,

University of California at San Francisco, and the University of Nairobi.

5. POPULATIONS BEING TARGETED

These programs target children living with HIV. Included among the populations served by these services

will be participants in US government funded research programs.

6. KEY LEGISLATIVE ISSUES ADDRESSED

This activity addresses legislative issues related to stigma and discrimination through community.

7. EMPHASIS AREAS

This activity includes minor emphases in commodity procurement, development of network/links/referral

systems, human resources, local organization capacity building, logistics, information, education, and

communication, and quality assurance and supportive supervision, targeted evaluation, and training.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15039

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15039 4232.08 HHS/Centers for University of 7020 483.08 $3,100,000

Disease Control & Washington

Prevention

7100 4232.07 HHS/Centers for University of 4301 483.07 $2,883,938

Disease Control & Washington

Prevention

4232 4232.06 HHS/Centers for University of 3253 483.06 $1,270,000

Disease Control & Washington

Prevention

Table 3.3.11:

Funding for Care: TB/HIV (HVTB): $80,000

ACTIVITY UNCHANGED FROM COP 2008

1.LIST OF RELATED ACTIVITIES

This activity relates to activities in Adult Care and Support, Pediatric Care and Support, Adult and Pediatric

ARV Services, PMTCT, and ARV Services.

2. ACTIVITY DESCRIPTION

The University of Washington (UW) will expand a long-standing research collaboration with the University of

Nairobi in the support of TB/HIV services at 3 delivery sites within Kenya. UW will offer TB screening to

6,500 HIV-infected patients and HIV testing for 300 TB patients; approximately 150 will be diagnosed with

TB/HIV. UW will support treatment services at Coptic Hospital, a faith-based facility in Nairobi that provides

services to both the general population and to individuals identified through research programs at the

University of Nairobi. In addition, UW will support treatment services to two "daughter" clinics (clinics

supported by the Coptic Church at facilities in Nyanza Province and in the industrial area of Nairobi). Funds

will be used to support improved screening and diagnosis. Refresher training of laboratory staff will be

initiated and basic laboratory microbiology capacity improved in order to meet the increased needs of TB

testing. 30 health care workers will be trained to provide clinical prophylaxis and/or treatment for TB to HIV-

infected individuals.

3. CONTRIBUTIONS TO OVERALL PROGRAM AREA

These activities will contribute towards the provision of integrated TB/HIV care by reducing TB morbidity

and mortality in HIV-infected individuals and also reducing HIV related morbidity and mortality in TB patients

co-infected with HIV. These activities will strengthen referral systems, improve diagnostics and treatment of

TB among HIV-positive patients, and strengthen capacity of health workers to provide integrated HIV and

TB services.

4. LINKS TO OTHER ACTIVITIES

The overall program activity links closely to Adult Care and Support, Pediatric Care and Support, Adult and

Pediatric ARV Services, PMTCT, and ARV Services currently supported by UW, and ART services

coordinated by and supported through the National AIDS and STD Control Program (NASCOP).

5. POPULATIONS BEING TARGETED

These activities target people living with HIV/AIDS. Public health care providers, including doctors, nurses,

pharmacists, laboratory workers will receive training in the diagnosis and management of TB using

government guidelines. .

6. KEY LEGISLATIVE ISSUES ADDRESSED

This activity addresses legislative issues related to stigma and discrimination through community

sensitization activities.

7. EMPHASIS AREAS

This activity includes minor emphases in commodity procurement, human resources, development of

networks/linkages/referral systems, local organization capacity development, quality assurance, quality

improvement and supportive supervision, and training.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15037

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15037 8830.08 HHS/Centers for University of 7020 483.08 $80,000

Disease Control & Washington

Prevention

8830 8830.07 HHS/Centers for University of 4301 483.07 $75,000

Disease Control & Washington

Prevention

Table 3.3.12:

Funding for Care: Orphans and Vulnerable Children (HKID): $150,000

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS FROM COP 2008:

+ The activity will be enhanced to include post disclosure support to normalize the experience of HIV in the

family, with a focus on households looking after HIV positive children under the Muangalizi model.

+ The activity will also support the evaluation of the Muangalizi pilot in collaboration with the other 4 USG

supported and participating sites to facilitate lessons learnt and identification and documentation of the

effectiveness of different approaches to facilitate scale up.

COP 2008

1. LIST OF RELATED ACTIVITIES

This activity relates to activities in Adult care and support, Adult ARV services, PMTCT, pediatric care and

support, Pediatric ARV services.

2. ACTIVITY DESCRIPTION

This activity was begun with 2007 plus-up funds and is part of a five-site effort to strengthen the link

between clinical and household settings for HIV+ children. All sites meet regularly with a sixth entity,

AED/Capable Partners, for real-time sharing of lessons learned and review the effectiveness of different

approaches in preparation for scale-up. The Muangalizi model is being tested in response to concern

expressed by clinicians that assuring optimal care for HIV+ OVC was difficult in many instance because

they were accompanied to different clinic visits by different relatives or community members, necessitating

constant re-education of adults managing care of children. Central to the approach is recruitment of adult

patients who are successfully managing their own care to accompany pediatric patients to all clinic visits

when a consistent caregiver from the household is not available. A total of 32 "accompagnateurs" will be

trained to be on watch for 150 children for development of side effects or complications, remunerated for

their time, and expected to perform home visits to monitor medication consumption. They will also be

expected to develop an ongoing and supportive relationship with the OVC household, assess the social

environment and refer for needed services, and seek wherever possible to identify a household or

community contact who can be prepared to assume the long-term responsibility of being a treatment

advocate for the child. Sites were carefully selected to represent a cross section of Nairobi and coastal

urban slum (Eastern Deanery, Coptic, and Bomu), peri-urban (AMPATH/Eldoret, Bomu) and rural (Kericho

District Hospital) communities. Standard measures of household and clinician satisfaction with the value-

added by the accompagnateur, accompagnatuer satisfaction with the experience, and clinical progress of

OVC participating in the program will be tracked. Numbers of OVC served are captured under care and

treatment activities.

3. CONTRIBUTIONS TO OVERALL PROGRAM AREA

These activities will contribute to the results of expansion of ART for clinically qualified HIV-positive children,

and strengthen referral networks for AIDS services.

4. LINKS TO OTHER ACTIVITIES

These activities link to non-ART services supported by University of Washington, referral to pediatric HIV

services provided at Coptic Hope Center and ART services coordinated by and supported through the

National AIDS and STD Control Program (NASCOP).

5. POPULATIONS BEING TARGETED

These activities target, children living with HIV/AIDS. A key focus of the family clinic is the provision of

services to children with HIV, and the identification of children with HIV as a way of reaching entire families

that are affected by HIV. Treatment services for diagnosis and treatment of very young children will be

established through a relationship with Kenya Medical Research Institute (KEMRI), whereby filter paper

samples are transported to the KEMRI lab for polymerase chain reaction (PCR) infant testing. Public health

care providers, including doctors, nurses, pharmacists, and laboratory workers are targeted for increased

HIV care and treatment knowledge and skills. Included among the populations served by these services will

be participants in U.S. government funded research programs.

6. KEY LEGISLATIVE ISSUES ADDRESSED

This activity addresses legislative issues related to stigma and discrimination through community

sensitization activities.

7. EMPHASIS AREAS

This activity includes minor emphasis in community mobilization, development of networks/linkages/referral

systems, human resources, and training.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15038

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15038 12475.08 HHS/Centers for University of 7020 483.08 $150,000

Disease Control & Washington

Prevention

12475 12475.07 HHS/Centers for University of 4301 483.07 $150,000

Disease Control & Washington

Prevention

Table 3.3.13:

Subpartners Total: $0
Coptic Hospital: NA
Cross Cutting Budget Categories and Known Amounts Total: $894,213
Public Health Evaluation $467,698
Public Health Evaluation $426,515