Detailed Mechanism Funding and Narrative

Years of mechanism: 2008 2009

Details for Mechanism ID: 288
Country/Region: Kenya
Year: 2009
Main Partner: University of California at San Francisco
Main Partner Program: NA
Organizational Type: University
Funding Agency: HHS/CDC
Total Funding: $7,800,000

Funding for Biomedical Prevention: Prevention of Mother to Child Transmission (MTCT): $550,000

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS FROM COP 2008:

+ Reaching Men As Partners by targeting 4,893 spouses of pregnant women

+ Providing Antiretroviral treatment for all infants and young children below 18 months who test HIV positive

by DNA PCR and initiating pregnant women in WHO stage 3 & 4 and those with CD 4 count of less than

350 on HAART.

+ The program will support and strengthen functional lab networks, decentralization and task shifting in

initiation and provision of ART within MCH for mothers and their HIV infected infants in an effort to improve

access to HIV care and treatment services including ART and will pilot extended HAART to cover the

breastfeeding period.

SECONDARY CROSS-CUTTING BUDGET ATTRIBUTIONS

This activity supports key attributions in human capacity development through the training of health care

service providers on PMTCT and other HIV prevention and care topics in order to equip them with

knowledge and skills to provide quality PMTCT services. These service providers include Doctors, Nurses,

Clinical Officers, Nutrition Officers and Health Record clerks. Other personnel targeted for training are the

mentor mothers and other peer counselors.

COP 2008

1. LIST OF RELATED ACTIVITIES

This activity relates to activities in HIV/AIDS treatment/ARV services and, TB/HIV.

2. ACTIVITY DESCRIPTION

University of California at San Francisco (UCSF) has been supporting palliative care and treatment services

in Nairobi and Nyanza provinces. The UCSF approach through its FACES program promotes family-

centered care for HIV rather than individuals with HIV. This innovative approach has ensured equity and

greater disclosure within families. Current PMTCT coverage is 33 out of 68 sites in Migori and 4 sites in

Kisumu. UCSF will implement comprehensive integrated PMTCT services in all facilities in Migori district

starting with high volume facilities offering Antenatal care, delivery and postnatal services, and will take up

some private facilities in Kisumu. Community peer support groups involving People Living with HIV (PLHIV)

will be formed and supported. In FY 2009, UCSF will implement integrated comprehensive PMTCT service

in accordance with the National Comprehensive PMTCT guidelines. Comprehensive integrated PMTCT

services include, but are not limited to counseling and testing of pregnant women and their partners in

antenatal clinics, delivery units and postnatal clinics using the opt-out approach, clinical staging of all HIV

positive women using WHO guidelines, CD4 testing of all HIV positive pregnant women, use of appropriate

antiretroviral regimens including HAART for maternal health, extended HAART to make breast feeding

safer, combined ARV prophylaxis in accordance to the National Antiretroviral therapy guidelines, postnatal

follow-up for the mother and exposed infants, initiation of cotrimoxazole prophylaxis to all exposed infants at

6 weeks, Early Infant Diagnosis (EID) at six weeks via PCR on Dry Blood Spots (DBS) from all exposed

infants and successful antiretroviral treatment of HIV-positive mothers, and infected infants. All infants who

test HIV positive by DNA PCR below 18 months of age will be started on antiretroviral treatment. UCSF will

provide counseling and testing to 24,463 (93%) of 26,189 pregnant women and provide antiretroviral

prophylaxis to 4,341 (93%) of 4647 HIV-positive women identified. Of the 4,341 HIV infected women 868

will be put on HAART, 2,171 on AZT+sdNVP and 1,302 sdNVP. Early Infant Diagnosis (EID) using Dry

Blood Spots (DBS) at six weeks and cotrimoxazole prophylaxis will target 2,605 HIV exposed infants. UCSF

will counsel and test 5,436 Men as Partners targeting 4893 spouses of pregnant women and Prevention

with Positives will be rolled out in health facilities to encourage knowledge of status, partner testing and

identification of discordant couples, supporting disclosure, risk reduction counseling and encouraging

condom use, adherence counseling, supporting STI diagnosis and treatment. Some PLWHAs who have

successfully gone through PMTCT will be trained as "Mother to Mothers" to enhance PMTCT advocacy and

community follow up of women and their infant to promote adherence, return for EID, FP and exclusive

breastfeeding for 6 months. In FY 09, 90 health care providers will be trained on comprehensive PMTCT,

and some health workers will be trained on PITC, family planning and counseling (numbers trained

depending on availability of funds). In total, UCSF will train and update skills of 120 service providers in

comprehensive HIV management for HIV-positive pregnant mothers, their infants and their families.

2. CONTRIBUTIONS TO OVERALL PROGRAM AREA

This activity will contribute to 1.9% of the overall 2009 Emergency Plan PMTCT targets for Kenya.

Community participation, male involvement, prevention with positives and mentor mother initiatives will

significantly contribute to PEPFAR goals for primary prevention, access to care and treatment, and support

of those affected and infected. Technical assistance to the Ministry of health facilities will contribute to

improvement of the quality of services. UCSF will facilitate capacity building of DHMTs for improved

management of health services and set up of referral networks and linkages for a continuum of care from

facilities to Home-based care within the community and among various programs within the district. This

activity will contribute to increased awareness, demand creation and stigma reduction leading to increased

utilization of services towards the goal of universal access to prevention, care and treatment services.

3. LINKS TO OTHER ACTIVITIES

This activity relates to KEMRI activities in HIV/AIDS treatment/ARV services and, TB/HIV. Linkages to HIV

care and treatment and to Family Planning services will be strengthened, to ensure immediate appropriate

care for the woman and exposed infants, and family members and thus optimize utilization of

complementary services created through Emergency Plan funding.

4. POPULATIONS BEING TARGETED

This activity targets children less than five years, adolescents of reproductive age 15-24, adults, pregnant

women and people living with HIV. Health care providers including doctors, nurses, and other health care

workers will be targeted for training on PMTCT using the national NASCOP CDC/WHO based curriculum.

5. KEY LEGISLATIVE ISSUES ADDRESSED

This activity will increase gender equity in HIV/AIDS programming through provision of HIV counseling and

testing services of pregnant women, and improved access to other HIV care programs for the HIV infected

Activity Narrative: woman, her infant and other family members. It will also reduce violence and coercion through stigma at the

community level.

6. EMPHASIS AREAS This activity includes emphasis on quality assurance and supportive supervision as

well as emphasis on Development of Network/Linkages/Referral Systems; Community

Mobilization/Participation, wrap around programs with Food/Nutrition, PMI through distribution of insecticide

treated nets at the MCH, safe motherhood through focused antenatal care, other Family planning initiatives

and TB screening and referral for treatment and care.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15020

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15020 8653.08 HHS/Centers for University of 7011 288.08 $550,000

Disease Control & California at San

Prevention Francisco

8653 8653.07 HHS/Centers for University of 4295 288.07 $340,000

Disease Control & California at San

Prevention Francisco

Emphasis Areas

Gender

* Increasing gender equity in HIV/AIDS programs

* Reducing violence and coercion

Health-related Wraparound Programs

* Child Survival Activities

* Family Planning

* Malaria (PMI)

* Safe Motherhood

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $30,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.01:

Funding for Biomedical Prevention: Prevention of Mother to Child Transmission (MTCT): $100,000

This PHE activity,"Integration of HIV Care and Treatment into MCH in Migori District, Kenya," was approved

for inclusion in the COP. The PHE tracking ID associated with this activity is KE.07.0055. A copy of the

progress report is included in the Supporting Documents section.

New/Continuing Activity: Continuing Activity

Continuing Activity: 17821

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

17821 17821.08 HHS/Centers for University of 7011 288.08 $100,000

Disease Control & California at San

Prevention Francisco

Emphasis Areas

Human Capacity Development

Public Health Evaluation

Estimated amount of funding that is planned for Public Health Evaluation $100,000

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.01:

Funding for Biomedical Prevention: Voluntary Medical Male Circumcision (CIRC): $520,000

Updated April 2009 Reprogramming. Increased by $270,000. Partnership Framework: UCSF is currently in

2 district hospital and 3 health centers. However, with additional support they can scale up outreach MC

services to outlying health centers and dispensaries.

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS FROM COP 2008:

+Specific AB messages will target both adult men and women with the aim to reduce multiple concurrent

partners.

COP 2008

1. ACTIVITY DESCRIPTION

University of California San Francisco (UCSF) has been supporting palliative care and treatment services in

Nairobi and Nyanza provinces, and PMTCT in Nyanza province. The UCSF approach through its FACES

program promotes family-centered care for HIV rather than individuals with HIV. This innovative approach

has ensured equity and greater disclosure within families. Current PMTCT coverage is 28 out of 68 sites in

Migori and 4 sites in Kisumu. In FY 2008, UCSF, in collaboration with the Kenya Ministry of Health (MOH)

will implement service delivery of male circumcision (MC) services in Migori and Rongo Districts in

accordance with the National and International Male Circumcision guidelines. FACES will roll out an

expanded pilot program to circumcise eligible men and boys, as well as neonatal infant boys. In addition to

medical service provision, MC services will include, but are not limited to linking with HIV counseling and

testing services for young men as a means to identify HIV-uninfected men who might choose male

circumcision, promotion of male circumcision at the clinic, and in the community as a means to prevent HIV

acquisition, promotion of other preventive methods for men (e.g. male condom, limiting number of sexual

partners, etc.), and promotion of infant male circumcision as a long-term strategy to decrease HIV incidence

in the population. Pregnant women presenting for ANC services will be counseled on the risk and benefits

of infant male circumcision. Printed materials will be given to expectant mothers to be shared with the

father. The materials will also outline the risk and benefits of male circumcision for the father. All men who

undergo male circumcision will be given information about the risk and benefits of having their sons undergo

the procedure, in addition to other risk reduction messages. Additional information will be available post-

natal at the MCH clinics where most children come for well-baby check-ups and vaccinations, and male

circumcision services will be provided for children whose parents consent. In FY 2008, 90 health care

providers will be trained to counsel parents about the risk and benefits of male circumcision, and 20

nurse/clinical officer teams will be trained to perform adult and infant male circumcision. 3,000 individuals

will be reached through this intervention. 10 condom outlets will be established.

2. CONTRIBUTIONS TO OVERALL PROGRAM AREA

Community participation and male involvement will significantly contribute to PEPFAR goals for primary

prevention, access to care and treatment, and support of those affected and infected. Technical assistance

to the Ministry of Health facilities will contribute to improvement of the quality of services. UCSF will facilitate

capacity building of DHMTs for improved management of health services and set up of referral networks

and linkages to ensure integration of prevention and care services at facilities, within the community and

among various related programs within the districts. This activity will contribute to increased awareness,

demand creation and stigma reduction leading to increased utilization of services towards the goal of

universal access to prevention, care and treatment services.

3. LINKS TO OTHER ACTIVITIES

Linkages to PMTCT and VCT, in particular, and HIV care and treatment services will be strengthened, to

increase demand for male circumcision and thus optimize utilization of complementary services created

through Emergency Plan funding. This activity relates to activities in HIV/AIDS treatment/ARV services

(#6945), PMTCT (#6949) and, TB/HIV (#6944). This activity will also link closely with IMPACT Research

programs in HVAB, HVOP, HVCT, HVSI, and OPHS, and will leverage training provided by IMPACT to

complement FACES' service delivery interventions.

4. POPULATIONS BEING TARGETED

This activity targets adults, pregnant women, HIV-positive pregnant women, HIV affected families, men and

boys, with a particular focus on adolescent males, and all male infants. Health care providers including

doctors, nurses and other health care workers will be targeted for training on prevention (including male

circumcision) counseling and performance of adult and infant male circumcision using the national

guidelines.

5. EMPHASIS AREAS / KEY LEGISLATIVE ISSUES ADDRESSED

This activity will address gender equity in HIV/AIDS programs through improved prevention service delivery

at health care facilities including ANC and MCH clinics. Male norms and behaviors will be addressed by

encouraging men to take responsibility in their sexual behavior, as well as by encouraging the participation

of men in helping to make decisions regarding their infant son's health. Community Health workers will

conduct community mobilization activities regarding prevention that will help increase uptake of male

circumcision and other prevention methods as well as address issues of stigma and discrimination at

community level. Human capacity development will be addressed through training of health workers; and

local organization capacity building will occur through technical assistance to the Ministry of Health to

strengthen the quality of their service delivery.

New/Continuing Activity: Continuing Activity

Continuing Activity: 17296

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

17296 17296.08 HHS/Centers for University of 7011 288.08 $200,000

Disease Control & California at San

Prevention Francisco

Emphasis Areas

Gender

* Addressing male norms and behaviors

* Increasing gender equity in HIV/AIDS programs

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $50,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.07:

Funding for Care: Adult Care and Support (HBHC): $750,000

Updated April 2009 Reprogramming. Decreased by $450,000. Funds moved to KEMRI (HBHC).

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS FROM COP 2008:

+ New activity emphasis on prevention with positives among patients coming for care and treatment

services.

COP 2008

1. LIST OF RELATED ACTIVITIES

This activity relates to activities in ARV Services, Counseling and Testing, TB/HIV, ART training, PMTCT,

pediatric care and support and pediatric ARV services.

2. ACTIVITY DESCRIPTION

The University of California at San Francisco (UCSF) will increase and strengthen its support at its existing

sites in Nairobi and Nyanza, as well as substantially expand services in 4 districts in Nyanza to include 10

sites in Kisumu East, 16 in Suba, 6 in Rongo and 14 in Migori. These activities will support palliative care

services for 46,500 people with HIV. Services will include diagnostic testing, ongoing counseling with a

particular focus on counseling for couples (including those with discordant HIV results), and prevention,

diagnosis, and management of opportunistic infections. Funds will support salaries for health care workers

and infrastructure through renovation in accordance with Emergency Plan guidance. In addition 50

individuals will be trained to provide HIV-related palliative care services. An area of emphasis for the UCSF

supported program is to manage families rather than individuals with HIV. The programs supported by

UCSF make extensive efforts to identify and provide treatment to family members of enrolled patients and

have structured care provision to optimize the provision of care to families. UCSF also works closely with

partners providing HIV prevention services to youth, and will provide youth-friendly HIV treatment services

to individuals referred from those programs. Other areas of focus include identification and provision of care

for children; integration of treatment with other services like TB, MCH and family planning, greater

involvement of PLWHAs as peer educators and strengthening commodity management system. UCSF is

collaborating with the National AIDS and STD Control Program (NASCOP) to develop a system for

telephone consultation that will allow care providers in rural areas to access HIV expertise. Additional

activities will include community mobilization and dissemination of informational materials to patients. UCSF

will maintain data concerning the numbers of people served and will report both nationally and through the

Emergency Plan.

Because of the geographic foci of the HIV epidemic in the United States, UCSF has vast experience

providing HIV care and has long been recognized as one of the premier institutions providing HIV care in

the United States (U.S.). The faculty of UCSF also has extensive experience developing training materials

and implementing HIV care and treatment programs in resource limited settings, including Kenya. Given

that UCSF has a long-standing research presence in Kenya, these activities will capitalize on the resulting

knowledge of Kenya as well as technical expertise in care and treatment. By March 2008, the established

patient care centers in Nairobi and Nyanza were providing palliative care services to more than 28,703

people with HIV.

3. CONTRIBUTIONS TO OVERALL PROGRAM AREA

These activities will contribute to the expansion of palliative care services for clinically qualified HIV-positive

patients, strengthened human resource capacity to deliver care services, and a strengthened referral

network for provision of those services. The activities will specifically support improved quality of care,

particularly for difficult to manage patients.

4. LINKS TO OTHER ACTIVITIES

This activity relates to Adult treatment, pediatric care and treatment activities, Counseling and Testing,

TB/HIV, PMTCT programs, OVC and to ART training.

5. POPULATIONS BEING TARGETED

These activities target people (adults, children, infants) living with HIV/AIDS, including participants in U.S.

government sponsored research programs, couples with HIV, discordant couples, and families. Services for

children with HIV are being established or expanded at all sites. Public health care providers, including

doctors, nurses, pharmacists, and laboratory workers are targeted for increased HIV care and treatment

knowledge and skills.

6. KEY LEGISLATIVE ISSUES ADDRESSED

This activity addresses legislative issues related to stigma and discrimination through involvement of

PLWHAs in service provision and community sensitization activities.

7. EMPHASIS AREAS

This activity includes minor emphasis in commodity procurement, development of networks, human

resources, local organization capacity building, logistics, community mobilization, information, education,

and communication, quality assurance and supportive supervision, and training.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15021

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15021 4137.08 HHS/Centers for University of 7011 288.08 $732,056

Disease Control & California at San

Prevention Francisco

7089 4137.07 HHS/Centers for University of 4295 288.07 $250,000

Disease Control & California at San

Prevention Francisco

4137 4137.06 HHS/Centers for University of 3219 288.06 $105,000

Disease Control & California at San

Prevention Francisco

Table 3.3.08:

Funding for Treatment: Adult Treatment (HTXS): $4,500,000

Updated April 2009 Reprogramming. Decreased by $300,000. Funds moved to KEMRI (HTXS).

ACTIVITY UNCHANGED FROM COP 2008

1. LIST OF RELATED ACTIVITIES

This activity relates to activities in Basic Care and Support, Counseling and Testing, TB/HIV, pediatric care

and support, pediatric ARV services, and PMTCT.

2. ACTIVITY DESCRIPTION

The University of California at San Francisco (UCSF) will increase and strengthen its support at its existing

sites in Nairobi and Nyanza Province. It will also substantially expand services within 4 districts in Nyanza to

include 10 sites in Kisumu East, 6 in Rongo, 16 in Suba and 14 in Migori. These activities and expansion

will support adult treatment services for 20,000 people with HIV (10,000 new patients). Services will include

diagnostic testing, ongoing counseling with a focus on counseling for couples (including those with

discordant HIV results), prevention, diagnosis, management of opportunistic infections and community

activities that strengthen the linkage between community care and treatment facilities. Funds will support

salaries for health care workers in accordance with Emergency Plan guidance, and will improve

infrastructure through renovation. An area of emphasis for the UCSF supported program is to manage

families rather than individuals with HIV. The programs supported by UCSF make extensive efforts to

identify and provide treatment to family members of enrolled patients, and are structured to optimize the

provision of care to families. UCSF also works closely with partners providing HIV prevention services to

youth and will provide youth-friendly HIV treatment services to individuals referred from those programs.

Other areas of focus include integration of treatment with other facility services like TB and OPD,

decentralization of services, greater involvement of PLWAs as peer educators, and strengthening the

commodity management system. In addition, UCSF will provide high-level technical assistance to sites in

Nyanza Province and will collaborate with the National AIDS and STD Control Program (NASCOP) in the

development of a system for telephone consultation that will allow care providers in rural areas to access

HIV expertise. Funding will be used to provide 50 health care workers with antiretroviral treatment (ART)

training. Additional activities will include community mobilization and dissemination of educational materials

to patients. UCSF will maintain data concerning the numbers of people served and will report both nationally

and through the Emergency Plan.

Because of the geographic distribution of the HIV epidemic in the United States (U.S.), UCSF has vast

experience in providing HIV care and has long been recognized as one of the premier institutions providing

HIV care in the U.S. The faculty of UCSF also has extensive experience in developing training materials

and implementing HIV treatment programs in resource limited settings, including Kenya. UCSF has a long-

standing research presence in Kenya and these activities will capitalize on their technical expertise in

treatment. By March 2008, the established centers in Nairobi and Nyanza were providing ARV treatment to

more than 9,000 people.

3. CONTRIBUTIONS TO OVERALL PROGRAM AREA

These activities will contribute to expansion of ART for clinically qualified HIV-positive patients,

strengthened human resource capacity to deliver ART, and an improved referral network for the provision of

ART. The activities will specifically support improved quality of care, particularly for difficult to manage

patients.

4. LINKS TO OTHER ACTIVITIES

This activity relates to other UCSF, KEMRI and International Medical Corps activities in Palliative Care,

Counseling and Testing, TB/HIV and PMTCT Pediatric care and support and Pediatric ARV services.

5. POPULATIONS BEING TARGETED

These activities target people (adults, children, infants) living with HIV/AIDS, including participants in U.S.

government sponsored research programs, couples with HIV, discordant couples, and families. Services for

children with HIV are being established or expanded at all sites. Public health care providers, including

doctors, nurses, pharmacists, and laboratory workers are targeted for increased HIV care and treatment

knowledge and skills.

6. KEY LEGISLATIVE ISSUES ADDRESSED

This activity addresses legislative issues related to stigma and discrimination through community

sensitization activities.

7. EMPHASIS AREAS

This activity includes minor emphasis in commodity procurement, development of networks, human

resources, local organization capacity building, logistics, quality assurance and supportive supervision and

targeted evaluation.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15023

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15023 4138.08 HHS/Centers for University of 7011 288.08 $4,500,006

Disease Control & California at San

Prevention Francisco

7090 4138.07 HHS/Centers for University of 4295 288.07 $2,572,607

Disease Control & California at San

Prevention Francisco

4138 4138.06 HHS/Centers for University of 3219 288.06 $1,680,825

Disease Control & California at San

Prevention Francisco

Table 3.3.09:

Funding for Care: Pediatric Care and Support (PDCS): $130,000

ACTIVITY UNCHANGED FROM COP 2008:

1. LIST OF RELATED ACTIVITIES

This activity relates to activities in Adult treatment, pediatric care and treatment, Counseling and Testing,

TB/HIV, and PMTCT.

2. ACTIVITY DESCRIPTION

The University of California at San Francisco (UCSF) will increase and strengthen its support at its existing

sites in Nairobi and Nyanza, as well as substantially expand services in 4 districts in Nyanza to include 10

sites in Kisumu, 16 in Suba, 6 in Rongo and 14 in Migori. These activities will support palliative care

services for 5,200 children exposed or with HIV. Services will include diagnostic testing; ongoing

counseling; and prevention, diagnosis, and management of opportunistic infections. Funds will support

salaries for health care workers and infrastructure through renovation in accordance with Emergency Plan

guidance, in addition to training 50 individuals to provide HIV-related care and support services. An area of

emphasis for the UCSF supported program is to manage families rather than individuals with HIV. The

programs supported by UCSF make extensive efforts to identify and provide treatment to family members of

enrolled patients and have structured care provision to optimize the provision of care to families. UCSF also

works closely with partners providing HIV prevention services to youth, and will provide youth-friendly HIV

treatment services to individuals referred from those programs. Other areas of focus include identification

and provision of care for children; integration of treatment with other services like TB, Pediatric filter clinics,

MCH and family planning; greater involvement of PLWHAs as peer educators and strengthening commodity

management system. UCSF is collaborating with the National AIDS and STD Control Program (NASCOP)

to develop a system for telephone consultation that will allow care providers in rural areas to access HIV

expertise. Additional activities will include community mobilization and dissemination of informational

materials to patients. UCSF will maintain data concerning the numbers of people served and will report both

nationally and through the Emergency Plan. Because of the geographic foci of the HIV epidemic in the

United States, UCSF has vast experience providing HIV care and has long been recognized as one of the

premier institutions providing HIV care in the United States. The faculty of UCSF also has extensive

experience developing training materials and implementing HIV care and treatment programs in resource

limited settings, including Kenya. Given that UCSF has a long-standing research presence in Kenya, these

activities will capitalize on the resulting knowledge of Kenya as well as technical expertise in care and

treatment. By March 2008, the established patient care centers in Nairobi and Nyanza were providing care

and support services to over 700 children exposed or with HIV.

3. CONTRIBUTIONS TO OVERALL PROGRAM AREA

These activities will contribute to the expansion of palliative care services for clinically qualified HIV-positive

patients, strengthened human resource capacity to deliver care services, and a strengthened referral

network for provision of those services. The activities will specifically support improved quality of care,

particularly for difficult to manage patients.

4. LINKS TO OTHER ACTIVITIES

This activity relates to Adult treatment, pediatric care and treatment activities, Counseling and Testing,

TB/HIV, PMTCT programs, OVC and to ART training.

5. POPULATIONS BEING TARGETED

These activities target people (adults, children, infants) living with HIV/AIDS, including participants in US

government sponsored research programs, couples with HIV, discordant couples, and families. Services for

children with HIV are being established or expanded at all sites. Public health care providers, including

doctors, nurses, pharmacists, and laboratory workers are targeted for increased HIV care and treatment

knowledge and skills.

6. KEY LEGISLATIVE ISSUES ADDRESSED

This activity addresses legislative issues related to stigma and discrimination through involvement of

PLWHAs in service provision and community sensitization activities.

7. EMPHASIS AREAS

This activity includes minor emphasis in commodity procurement, development of networks, human

resources, local organization capacity building, logistics, community mobilization, information, education,

and communication, quality assurance and supportive supervision, and training.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15021

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15021 4137.08 HHS/Centers for University of 7011 288.08 $732,056

Disease Control & California at San

Prevention Francisco

7089 4137.07 HHS/Centers for University of 4295 288.07 $250,000

Disease Control & California at San

Prevention Francisco

4137 4137.06 HHS/Centers for University of 3219 288.06 $105,000

Disease Control & California at San

Prevention Francisco

Table 3.3.10:

Funding for Treatment: Pediatric Treatment (PDTX): $550,000

ACTIVITY UNCHANGED FROM COP 2008:

1. LIST OF RELATED ACTIVITIES

This activity relates to activities in ARV Services (#7090, #6945), Counseling and Testing (#6941, #6907),

TB/HIV (#9054, #6944), ART training (#6991), PMTCT (#6949), pediatric care and support and pediatric

ARV services.

2. ACTIVITY DESCRIPTION

The University of California at San Francisco (UCSF) will increase and strengthen its support at its existing

sites in Nairobi and Nyanza provinces. It will also substantially expand services in 4 districts in Nyanza to

include 10 sites in Kisumu East, 2 Rongo, 13 in Suba and 7 in Migori. These activities will support pediatric

treatment services for 1,500 children (810 new patients) exposed and/or with HIV. This results in a total of

1,800 ever receiving treatment. Services will include diagnostic testing, prevention, diagnosis, management

of opportunistic infections and community activities that strengthen the linkage between community care

and treatment facilities. Funds will support salaries for health care workers in accordance with Emergency

Plan guidance, and will improve infrastructure through renovation. An area of emphasis for the UCSF

supported program is to manage families rather than individuals with HIV. The programs supported by

UCSF make extensive efforts to identify and provide treatment to family members of enrolled patients, and

are structured to optimize the provision of care to families. UCSF also works closely with partners providing

HIV prevention services to youth and will provide youth-friendly HIV treatment services to individuals

referred from those programs. Other areas of focus include integration of treatment with other facility

services like TB and OPD, decentralization of services, greater involvement of PLWAs as peer educators,

and strengthening the commodity management system. In addition, UCSF will provide high-level technical

assistance to sites in Nyanza Province and will collaborate with the National AIDS and STD Control

Program (NASCOP) in the development of a system for telephone consultation that will allow care providers

in rural areas to access HIV expertise. Funding will be used to provide 50 health care workers with

antiretroviral treatment (ART) training. Additional activities will include community mobilization and

dissemination of educational materials to patients. UCSF will maintain data concerning the numbers of

people served and will report both nationally and through the Emergency Plan. Because of the geographic

distribution of the HIV epidemic in the United States (U.S.), UCSF has vast experience in providing HIV care

and has long been recognized as one of the premier institutions in providing HIV care in the U.S. The

faculty of UCSF also has extensive experience developing training materials and implementing HIV

treatment programs in resource limited settings, including Kenya. UCSF has a long-standing research

presence in Kenya and the activities will capitalize on their technical expertise in treatment. By April 2008,

the established centers in Nairobi and Nyanza were providing ART to more than 700 children.

3. CONTRIBUTIONS TO OVERALL PROGRAM AREA

These activities will contribute to expansion of ART for clinically qualified HIV-positive patients,

strengthened human resource capacity to deliver ART, and an improved referral network for the provision of

ART. The activities will specifically support improved quality of care, particularly for difficult to manage

patients.

4. LINKS TO OTHER ACTIVITIES

This activity relates to other UCSF, KEMRI and International Medical Corps activities in care and support,

Counseling and Testing, TB/HIV, and PMTCT.

5. POPULATIONS BEING TARGETED

These activities target people (adults, children, infants) living with HIV/AIDS, including participants in U.S.

government sponsored research programs, couples with HIV, discordant couples, and families. Services

for children with HIV are being established or expanded at all sites. Public health care providers, including

doctors, nurses, pharmacists, and laboratory workers are targeted for increased HIV care and treatment

knowledge and skills.

6. KEY LEGISLATIVE ISSUES ADDRESSED

This activity addresses legislative issues related to stigma and discrimination through community

sensitization activities.

7. EMPHASIS AREAS

This activity includes minor emphasis in commodity procurement, development of networks, human

resources, local organization capacity building, logistics, quality assurance and supportive supervision and

targeted evaluation.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15023

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15023 4138.08 HHS/Centers for University of 7011 288.08 $4,500,006

Disease Control & California at San

Prevention Francisco

7090 4138.07 HHS/Centers for University of 4295 288.07 $2,572,607

Disease Control & California at San

Prevention Francisco

4138 4138.06 HHS/Centers for University of 3219 288.06 $1,680,825

Disease Control & California at San

Prevention Francisco

Table 3.3.11:

Funding for Care: TB/HIV (HVTB): $400,000

Updated April 2009 Reprogramming. Decreased by $150,000. Funds moved to KEMRI (HVTB).

ACTIVITY UNCHANGED FROM COP 2008

1. LIST OF RELATED ACTIVITIES

This activity relates to activities in Adult ARV Services , Counseling and Testing , and PMTCT , pediatric

care and support, Pediatric ARV services.

2. ACTIVITY DESCRIPTION

University of California at San Francisco (UCSF) will support TB/HIV services at 6 sites in Nairobi and

Nyanza Provinces. TB screening for 12,000 HIV patients and HIV screening for 1,600 TB suspects/patients

will be offered as a standard of care in all the facilities; approximately 1,000 patients will be identified as

being infected with both TB and HIV. Funds will support refresher training of laboratory staff and

improvement of basic laboratory microbiology capacity in order to meet the increased needs for TB testing.

Twenty-five health care workers will be trained to provide clinical prophylaxis and/or treatment for TB to HIV

-infected individuals. Additional activities will include community mobilization and follow up, dissemination of

educational materials to patients. UCSF will maintain data concerning the numbers of people served and

will report both nationally and through the Emergency Plan. Because of the geographic foci of the HIV

epidemic in the United States, UCSF has vast experience providing HIV care and has long been recognized

as one of the premier institutions providing HIV care in the US. The faculty of UCSF also has extensive

experience developing training materials and implementing HIV treatment programs in resource limited

settings, including Kenya. UCSF has a long-standing research presence in Kenya whose activities will

capitalize on their technical expertise in treatment.

3. CONTRIBUTIONS TO OVERALL PROGRAM AREA

These activities will contribute towards the provision of integrated HIV/TB services for dually infected

patients care by reducing TB morbidity and mortality in HIV-infected individuals and also reducing HIV

related morbidity and mortality in TB patients co-infected with HIV. These activities will strengthen referral

systems, improve diagnostics and treatment of TB among HIV-positive patients and strengthen capacity of

health workers to provide integrated HIV and TB service.

4. LINKS TO OTHER ACTIVITIES

The overall program activity links closely to Adult Care and Support, Pediatric Care and Support, Adult and

Pediatric ARV Services currently supported by this partner, Counseling and Testing provided by KEMRI and

IMC, and PMTCT.

5. POPULATIONS BEING TARGETED

These activities target people living with HIV/AIDS. Public health care providers, including doctors, nurses,

pharmacists, laboratory workers will receive training in the diagnosis and management of TB using

government guidelines.

6. KEY LEGISLATIVE ISSUES ADDRESSED

This activity addresses legislative issues related to stigma and discrimination through community

sensitization activities.

7. EMPHASIS AREAS

This activity includes minor emphasis in commodity procurement, development of networks/linkages/referral

systems, community mobilization, human resources, local organization capacity development, quality

assurance, quality improvement and supportive supervision, and training.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15022

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15022 9054.08 HHS/Centers for University of 7011 288.08 $350,614

Disease Control & California at San

Prevention Francisco

9054 9054.07 HHS/Centers for University of 4295 288.07 $175,000

Disease Control & California at San

Prevention Francisco

Table 3.3.12:

Funding for Testing: HIV Testing and Counseling (HVCT): $100,000

ACTIVITY UNCHANGED FROM COP 2008

1. ACTIVITY DESCRIPTION & EMPHASIS AREAS

University of California San Francisco (UCSF), through its Family AIDS Care and Education Services

(FACES) program, promotes family-centered, comprehensive HIV/AIDS care in Nyanza and parts of

Nairobi. UCSF partners with the Ministry of Health and other local health facilities to provide services with

an emphasis on strengthening local capacity for long-term local sustainability. In 2008, UCSF received

PEPFAR funding though the US Centers for Disease Control and Prevention (CDC) to initiate provider

initiated HIV testing and counseling (PITC) in Migori, Rongo and Kisumu districts of Nyanza province and in

Nairobi.

PITC will be provided as part of routine care within outpatient and inpatients departments in all the health

facilities in the said districts. Also, USCF will promote HIV counseling and testing for the sexual partners

and family members of the patients enrolled in the care and treatment services in the facility. UCSF will aim

to offer HIV testing to every patient visiting a health facility regardless of the attending illness. This will lead

to an increase in HIV case identification, HIV status knowledge, and enrollment into care and treatment

services. UCSF will encourage HIV counseling and testing in TB, OPD, in-patient wards, male circumcision

service departments, and in the community in keeping with the Kenya MOH community strategy. They will

strengthen linkages between testing sites and HIV care and treatment. PLWHA will be involved in patient

counseling, HIV education, and non-medical clinic work to inspire testing, positive living, and reduce

perceived stigma.

Linkages from PITC to palliative care and treatment will optimize utilization of complementary services

created through Emergency Plan funding. Patients testing positive in integrated care and treatment sites will

enroll in palliative care within that department to streamline services and prevent unmet referral loss. At

non-integrated HIV sites, HIV positive patients will be referred to the closest care and treatment department

or facility for palliative care enrollment. When possible, staff will escort patients to the HIV care service

point.

As part of the family model of care, the Family Information Table will be used at HIV care encounters with

index patients to boost recruitment for testing, and to identify and enroll partners and family members at HIV

risk. Counseling and Prevention with Positives activities will emphasize partner and child testing, provide

assisted disclosure counseling, as well as provide risk reduction services. Concentrated pediatric

counseling and testing strategies will increase pediatric case identification and uptake of services.

UCSF will also provide training, mentorship, and supportive supervision for all the PITC providers in the

respective regions. Health care providers previously trained in HIV counseling and testing will receive

sensitization training on PITC to update, sensitize, and increase PITC skills. UCSF will support MOH

supportive supervision, allowing a nurse counselor to visit sites three days per month for structured

mentorship.

By March 2010, the UCSF Counseling and Testing support will provide PITC services to more than 25,000

individuals in 50 health facilities in Nyanza and Nairobi. To facilitate this, UCSF will train at least 300 health

care workers.

2. CONTRIBUTIONS TO OVERALL PROGRAM AREA

These activities will significantly contribute to national prevention and treatment goals by averting new

infections and pro-longing life through palliative care enrollment and ART treatment; strengthen local human

resource capacity to provide quality health care services; and strengthen referral networks and linkages for

integration of prevention and care services at facilities.

3. LINKS TO OTHER ACTIVITIES

This activity is associated with ART (adult and pediatric), Prevention of Mother to Child Transmission, Male

Circumcision and TB-HIV.

4. POPULATIONS BEING TARGETED

These activities target infants, children, and adults living with HIV/AIDS, including participants in U.S.

government sponsored research programs, couples with HIV, discordant couples, and families. HIV testing

services for exposed infants and children are emphasized at all supported sites. Public health care

providers, including doctors, nurses, and lay health workers are targeted for increased HIV care and

treatment knowledge and skills.

5. SECONDARY CROSS-CUTTING BUDGET ATTRIBUTIONS

There are no secondary cross-cutting budget attributions in this activity.

New/Continuing Activity: Continuing Activity

Continuing Activity: 19411

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

19411 19411.08 HHS/Centers for University of 7011 288.08 $100,000

Disease Control & California at San

Prevention Francisco

Emphasis Areas

Gender

* Increasing gender equity in HIV/AIDS programs

Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.14:

Funding for Strategic Information (HVSI): $200,000

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS FROM COP 2008:

+ Revision of the protocol in compliance with the OGAC guidelines on conducting multi-country targeted

evaluations. This SI component of this activity remains the same as indicated in COP 2008.

SECONDARY CROSS-CUTTING BUDGET ATTRIBUTIONS

This activity supports key cross-cutting attributions in human capacity development by training health

workers and data handling staff on the use of reporting tools and monitoring and evaluation.

COP 2008

The only changes since approval in 2007 COP are:

+Activities initiated in '07 will continue in '08, but this will be transitioned to UCSF since the UTAP

mechanism is no longer available in '08.

+Technical assistance in cost-effectiveness analyses will be an expanded component of this activity in '08,

together with the translation of evaluation findings into relevant policy.

+In addition to technical support for the comprehensive trial, this activity will involve capacity building in data

analysis, writing, and policy translation support. This activity will support current PEPFAR partners to

analyze and use existing program data to improve program quality and inform policy development. Through

a series of trainings and workshops, this activity will help to develop Kenyan professional capacity for

epidemiological analysis and translation into policy.

+In '08 this activity will also involve the translation of study instruments, particularly Standard Operating

Procedures (SOPs) into programmatic tools that implementing partners can use.

1. ACTIVITY DESCRIPTION

This activity will continue work initiated in '07 under the UCSF/UTAP mechanism to provide technical

assistance for several plus-up activities. To support development and implementation of the Comprehensive

Package Study, UCSF is supporting KEMRI, NASCOP and CDC-Kenya to develop a study protocol, study

instruments, and procedure manual for this important Public Health Evaluation. This evaluation, which is a

collaboration of KEMRI, NASCOP, and the USG PEPFAR team will assess the population-level impact on

HIV incidence of a prevention package that includes VCT and Male Circumcision. The evaluation will also

assess the population-level impact on mortality and morbidity of widespread provision of care and treatment

within the CDC/KEMRI Demographic Surveillance System. In addition, UCSF staff are providing technical

assistance for training and supervision of study staff and overall supervision of the project. A key

component of the technical assistance will be the training of Kenyan counterparts in all components of

epidemiological evaluation. This human capacity development is a key component of this project.

2. CONTRIBUTIONS TO OVERALL PROGRAM AREA [

This program will provide important information needed to assess the effectiveness of the prevention

interventions on HIV incidence in the DSS area. The epidemiological data will inform the design of

prevention packages and referral mechanism to care and treatment.

3. LINKS TO OTHER ACTIVITIES

This activity will link to SI support to NASCOP and KEMRI as well as to Public Health Evaluation activities.

4. POPULATIONS BEING TARGETED

This activity will provide training for adult men and women.

5. EMPHASIS AREAS / KEY LEGISLATIVE ISSUES ADDRESSED

Emphasis areas for this national activity include human capacity development, training, in-service training,

retention strategies, local organization capacity building and strategic information strengthening.

6. TARGETS

Number of organizations offered TA- 3

Number of individuals trained on surveillance, HMIS and/or M&E - 20

New/Continuing Activity: Continuing Activity

Continuing Activity: 19426

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

19426 19426.08 HHS/Centers for University of 11996 11996.08 UTAP $635,000

Disease Control & California at San

Prevention Francisco

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $75,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.17:

Cross Cutting Budget Categories and Known Amounts Total: $255,000
Human Resources for Health $30,000
Public Health Evaluation $100,000
Human Resources for Health $50,000
Human Resources for Health $75,000