Detailed Mechanism Funding and Narrative

Years of mechanism: 2008 2009

Details for Mechanism ID: 673
Country/Region: Ethiopia
Year: 2009
Main Partner: Ministry of Health - Ethiopia
Main Partner Program: Ethiopian Health and Nutrition Research Institute
Organizational Type: Host Country Government Agency
Funding Agency: HHS/CDC
Total Funding: $7,000,000

Funding for Care: TB/HIV (HVTB): $1,000,000

improving Diagnosis of TB in HIV Positive Persons & Introducing Liquid Culture Diagnosis

ACTIVITY UNCHANGED FROM FY2008 (no Update needed)

Tuberculosis (TB) is the most common cause of death among HIV-infected persons, but diagnosis of TB in

these persons is difficult. In addition, the global burden of drug-resistant TB in HIV-infected persons is

increasing and can only be addressed through accurate diagnosis of drug-resistant TB. Improving the

diagnosis of TB in HIV-positive persons was one of Ethiopia's emphasis areas in FY07. Using plus-up

funding from 2007, the Ethiopian Health and Nutrition Research Institute (EHNRI) sought to increase TB

culture capacity in five regional laboratories through renovations of existing facilities, procurement of

appropriate supplies, training of regional staff, and ensuring quality assurance and control. In FY08, EHNRI

will build on that work by implementing liquid TB culture, which is the most rapid and sensitive method for

TB diagnosis, and drug-susceptibility testing at these five regional laboratories. This will maximize the

sensitivity and speed of TB diagnosis and the identification of drug-resistant TB.

EHNRI will work with the Federal Ministry of Health (MOH), regional health bureaus (RHB), and PEPFAR

partners to realize these activities. Activities will include:

1) Site assessments

2) Renovation of existing laboratory facilities for appropriate biosafety precautions

3) Procurement of equipment and reagents

4) Training of regional staff

5) Implementation of liquid-culture diagnosis

6) Transport of specimens from health facilities to regional laboratories

7) Internal and external quality assurance

8) Provision of technical assistance

9) Appropriate monitoring and evaluation

In addition, the national reference laboratory needs support for its work with a network of regional

laboratories to enhance TB culture-capacity. To do this, an additional three staff members will need to be

hired by EHNRI, and their staff should be re-trained in liquid-culture techniques. A study tour that would

bring EHNRI staff to a laboratory with such activities is under consideration.

New/Continuing Activity: Continuing Activity

Continuing Activity: 16652

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16652 12314.08 HHS/Centers for Ethiopian Health 7490 673.08 Expansion of $1,634,280

Disease Control & and Nutrition HIV/AIDS/STI/T

Prevention Research Institute B Surveillance

and Laboratory

Activities in the

FDRE

12314 12314.07 HHS/Centers for Ethiopian Health 5493 673.07 $1,330,000

Disease Control & and Nutrition

Prevention Research Institute

Emphasis Areas

Construction/Renovation

Health-related Wraparound Programs

* TB

Military Populations

Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.12:

Funding for Laboratory Infrastructure (HLAB): $1,800,000

Specimen Management and Referral Services

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

Ethiopia has four-tier public health laboratory system and has started implementation of Maputo consensus

meeting recommendations. EHNRI will lead the coordinated effort of sample transfer in the tier system with

emphasis on integration and capacity development for logistic system and smooth coordination and

collaboration between the testing and referring sites

COP 08 NARRATIVE:

Ethiopia has four a tier public health laboratory system and has started implementing the Maputo

consensus meeting recommendations. Even though it is weak, the laboratories across the tier have been

linked with the specimen referral system. Most health facilities are in the process of being equipped with

basic equipments. Hence referral-testing services are extremely important. In order to offer laboratory-

monitoring services (CD4, and other basic tests) for PLWHA, including children and pregnant women, a

sample referral system was established. Clinical samples are transported from outlying clinics to referral

laboratories where equipment and human resources are available. To enroll patients and monitor the

efficacy of ART, basic and advanced laboratory tests are required: CD4, biochemical and hematology

profiles at specified period of time as per the guidelines for ARV use in Ethiopia. However, most of the

health centers and some peripheral hospitals involved in ART implementation do not have the capacity to

support laboratory services.

The sample referral system in the interim period was supported by University partners. This activity later

has been supported by Ethiopian Health and Nutrition Research Institute (EHNRI). EHNRI with the support

of partners has developed Standard Operating Procedures (SOPs) and guidelines for the specimen

transport and referral testing services nationwide. EHNRI with the Regional Health Bureau/Regional

Reference laboratories has been leading the effort of referral services for peripheral hospitals and health

centers. In addtion, EHNRI provided techncial assistance in quantification and purchasing of laboratory

supplies, including diagnosis and monitoring reagents and distributed them to laboratories for diagnostic

and monitoring tests requested through referral at the facility-based levels. Nonetheless, specimen

management and referrals are still weak and require a reliable courier system as well as strengthened

coordination and communication across the referring labs or sites and testing laboratories.

In FY09, EHNRI will lead the nationwide coordinated effort of specimen referral for CD4, chemistry,

hematology, viral load, and DNA PCR-based early infant diagnosis. EHNRI, with the regional laboratories,

will work to strengthen logistic system for improving TB diagnosis; to support EQA for hospital and health

center laboratories and to ensure ownership and sustainability of the program. EHNRI will procure safety

materials, cold boxes, thermometers and related supplies to address safety and quality for sample referral

testing. As a continuation of COP08 activity, specific training on specimen management, transport, and

storage, recording and reporting will be provided. The specimen management, transport, and referral

system will be followed using the strict guidelines and Standard Operating Procedures (SOP) developed by

EHNRI. Additional SOP and guides will be distributed to the laboratories that are newly initiating the referral

testing services. The National HIV Laboratory will continue providing referral diagnostic services for

HIV/TB/STI drug resistance and EQA including HIV DNA PCR for infant diagnosis, CD4, hematology, and

chemistry tests.

The logistic support for referral testing will be supported through courier system. Within this system non-

laboratory personnel will be trained on sample storage, transportation and safety during sample

transportation. This includes transport of specimens and results to and from health centers to the next level

hospital or regional laboratories and/or to National HIV Reference laboratory. PEPFAR provide technical

support to EHNRI and regional laboratories for effective coordination and implementation of the referral

testing services.

The lab tests done at the hospital laboratories are returned within two days. It is anticipated that the turn-

around time from health center to test sites and back to the clinic will be 2-3 additional days. For better

management of sample transfer and to deliver appropriate results timely, patient tracking numbers and

tracking sheets will be used during receipt and delivery. Samples are collected in test-specific containers

that already contain necessary preparation reagents. After the samples are collected, the laboratory request

form are included in the collection container, sample placed in a cooler, and transported. All the regular

samples are transported in cool gel packs. In order to maintain integrity of samples, the local samples are

delivered within a day using cargo or courier mode.

The facilities that send the sample will work very closely and communicate regularly with the facilities testing

the samples. Commonly agreed upon sample and result delivery schedule will be developed and

coordinated regularly. More than 320 health centers and 25 peripheral hospitals will be linked to the nearby

referral hospitals or regional laboratories for ART monitoring. More than 200 health centers and hospitals

will provide early infant diagnosis through sample referrals to 7 testing sites including the national reference

laboratory.

New/Continuing Activity: Continuing Activity

Continuing Activity: 16653

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16653 10612.08 HHS/Centers for Ethiopian Health 7490 673.08 Expansion of $1,900,000

Disease Control & and Nutrition HIV/AIDS/STI/T

Prevention Research Institute B Surveillance

and Laboratory

Activities in the

FDRE

10612 10612.07 HHS/Centers for Ethiopian Health 5493 673.07 $1,565,550

Disease Control & and Nutrition

Prevention Research Institute

Table 3.3.16:

Funding for Laboratory Infrastructure (HLAB): $100,000

Expansion of Laboratory Information System

ACTIVITY UNCHANGED FROM FY2008

Information, in the form of test results and clinical investigation, is the primary product of the clinical

laboratory. To meet the needs of the laboratory's consumers, it is essential that this information is accurate,

available, and timely. Laboratory Information System (LIS) supports workflow and information flow in all

steps of the laboratory testing process, including patient registration, test ordering, sample collection,

testing, and reporting. LIS enables laboratories to manage their data, to maintain quality, and to improve

efficiency. In developing countries, almost all laboratories meet these needs with a manual information

system, but the scale-up of ART and monitoring programs forces these laboratories to implement a

computer-based LIS to handle the ever-increasing volume of data that they receive and report out. There

are a number of challenges as, piloting and implementing of LIS continues, some of which include the lack

of network availability at different facilities and difficulty in finding facilities that can support the system.

Laboratory Information System (LIS) support has been piloted and the system is functioning at national and

Regional reference laboratories and selected hospital laboratories. Prior to this several trainings were

provided to laboratory technologists and IT managers who use and support the software, respectively.

Strengthening and expansion of activities started in FY08 and will be continued in FY09 at EHNRI and 8

other facilities. Electronic-based LIS will be strengthened to support operations and quality-assurance

activities at the Ethiopian Health and Nutrition Research Institute (EHNRI), regional laboratories, and

PEPFAR-supported ART hospital laboratories. LIS will enable sites to have efficient data and report

exchanges. To achieve this, the following activities will occur (1) procure additional LIS software site and

accessories for 8 sites; (2) procure barcode printers, barcode readers, and barcode printer paper; (3)

provide refresher training to laboratory technicians and receptionists in LIS; (4) procure computers and

accessories; (5) support peer-to-peer network for regional and hospital laboratories including broadband

internet, networking and cabling; (6); support operational cost (7) provide technical and logistic costs; and

(8) local human capacity development.

The planned activities will also include strengthening the paper based LIS in all facilities especially in those

sites where electronic LIS is not established. EHNRI will coordinate and closely work with regional

laboratories, CDC and Association of Public Health Laboratories (APHL).

New/Continuing Activity: Continuing Activity

Continuing Activity: 17828

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

17828 17828.08 HHS/Centers for Ethiopian Health 7490 673.08 Expansion of $350,000

Disease Control & and Nutrition HIV/AIDS/STI/T

Prevention Research Institute B Surveillance

and Laboratory

Activities in the

FDRE

Table 3.3.16:

Funding for Laboratory Infrastructure (HLAB): $1,100,000

Equipment Maintenance and Technical Support for Laboratory Services

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

In FY09, EHNRI will implement the Maputo Declaration on strengthening of laboratory systems with

emphasis on equipment standardization and service contracts for equipments at various levels of the tiered

system. EHNRI will consolidate equipment preventative and curative maintenance mechanism of bundling

with manufacturers. EHNRI will develop a sustainable national system of preventative and curative

maintenance across the tiered laboratory network.

The Ethiopian Health and Nutrition Research Institute (EHNRI) is the technical arm of the Ministry of Health

(MOH) responsible for providing guidance to laboratory services. EHNRI is the lead institution in

coordinating laboratory programs in Ethiopia with a strategic national plan to support integrated disease

laboratory services. Preventive and curative equipment maintenance constitutes a key component of the

national laboratory strategic plan.

EHNRI provided technical assistance to strengthen laboratory quality service at all levels of the laboratory

network: technical assistance including preventive and curative maintenance services of equipment,

inventory laboratory management and on-site practical trainings, follow up and supportive supervision were

provided to all ART hospital laboratories. Equipment preventative maintenance and curative maintenance

play a critical role in ensuring quality laboratory testing and uninterrupted service delivery as ART services

are rolled out.

In FY08, preventive and curative maintenance service was provided for major laboratory equipment at all

expanded 131 hospitals, 240 health centers and ten regional laboratories. Preventive maintenance and

calibration of major equipments including centrifuges, FACS counts, hematology and chemistry analyzers

were provided quarterly at all sites where the equipments were installed. Broken machines repaired and

spare parts changed to prevent/minimize service interruption. Technical assistance included maintenance

and troubleshooting of laboratory equipments (fridges, freezers, microscopes, incubators, autoclaves,

chemistry analyzers, hematology analyzers and FACS count machines) at all ART hospitals and health

centers. PEPFAR also provided technical assistance in developing standard operating procedures for use

during instrument operation, developing preventative maintenance and maintenance logs, training of

laboratory personnel and monitoring them on how to perform preventative maintenance. There are

challenges in the establishment and implementation of a sustainable preventive and curative maintenance

system across the country. Some of these challenges include training, availability of spare parts and

protracted negotiations with vendors on establishing maintenance contracts. The establishment of

maintenance contract is imperative for major and sensitive equipment including thermocycler, centrifuges,

ELISA washer, ELISA reader, centrifuges, chemistry and hematology analyzers, FACS count, FACS

calibur, freezers, refrigerators, incubators, biosafety cabinet, microscopes, biosafety cabinets. EHNRI has

encountered difficulties setting up curative maintenance contracts with major manufacturers of equipments

resulting to a protracted process. EHNRI is pursuing a maintenance mechanism (through SCMS) termed

"Bundling" with one of the manufacturers of an instrument routinely used in Ethiopia. Bundling is the

agreement whereby prices of reagents are negotiated with a manufacturer of equipment to include the

required maintenance of that equipment. Bundling has the added benefit in that it compels the vendor to

maintain equipment in order to consume reagents supplied by vendor.

EHNRI is also committed to the implementation of the "Maputo Declaration on Strengthening of Laboratory

Systems" which emphasizes list of supplies and tests needed at each level of an integrated laboratory

network, standardization of laboratory equipment at each level of the tiered laboratory and considerations to

guide maintenance and service contracts for equipment at various levels of the laboratory network.

During FY09, all the above mentioned activities will continue and be expanded to additional new sites with

emphasis on developing a sustainable national system on preventive and curative maintenance. This will

entail an equipment maintenance policy that addresses national reference, as well as regional, district and

health centers laboratories. Such a policy will inform equipment maintenance which actually begins with the

selection and acquisition of suitable testing platforms as well as equipment inventory. Support will be

provided for purchase of critical spare parts for national and regional laboratories and establishment of the

Equipment Maintenance Center at EHNRI. The technical support will continue and expand to new sites

initiating ART services including health center laboratories. Technical assistance including curative and

preventive maintenance of equipment, functional and structural organization of laboratory, on the job

training in test procedures, specimen management, data recording, and reporting, inventory laboratory

management, on-site practical trainings and follow up and supportive supervision will be provided in

collaboration with other partners. Technical support includes inventory and laboratory management for

maintenance of clinical laboratory services and ensures laboratory standards are implemented at all ART

hospital, health center and VCT laboratories. Review of existing laboratory operating procedures, recording

and reporting at facility levels will be performed. Training of required number of engineers for preventive and

curative maintenance of equipment at the national reference as well as regional, district and health centers

laboratories will be emphasized. Engineers will be trained such that they will be able to identify equipment

fault for appropriate action to be taken as well as perform calibration of common laboratory equipment such

as thermometers, timers, pipettes. Also ensuring proper mechanisms for reporting of damaged equipment

to regional and reference laboratories with proper documentation is in place. Ensuring equipment

maintenance contracts are in place with manufacturers or their local representatives with periodic evaluation

of the service they provide. Support of the above activities will enable a sustainable preventative and

curative maintenance system that addresses an integrated laboratory service for equipment maintenance,

builds local capacity and ensure accurate, reliable and reproducible results are provided to client.

New/Continuing Activity: Continuing Activity

Continuing Activity: 16655

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16655 10607.08 HHS/Centers for Ethiopian Health 7490 673.08 Expansion of $1,500,000

Disease Control & and Nutrition HIV/AIDS/STI/T

Prevention Research Institute B Surveillance

and Laboratory

Activities in the

FDRE

10607 10607.07 HHS/Centers for Ethiopian Health 5493 673.07 $1,021,300

Disease Control & and Nutrition

Prevention Research Institute

Table 3.3.16:

Funding for Laboratory Infrastructure (HLAB): $1,800,000

Laboratory Quality Assurance Program

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS: (insert a maximum of 5000 character

narrative here):

EHNRI will make the QA program comprehensive and include TB and Malaria smear microcopy, DNA-PCR

based early infant diagnosis and viral load assays for advanced clinical monitoring. In addition to the

National External Quality Assessment Schemes (NEQAS), EHNRI will support and strengthen Regional

Quality Assessment Schemes (REQAS). EHNRI will also ensure the implementation of Maputo declaration.

The Ethiopian Health and Nutrition Research Institute (EHNRI) is the technical arm of the Ethiopian Ministry

of Health (MOH) responsible for providing guidance to laboratory services. It is the lead institution in

coordinating laboratory programs in Ethiopia, and has a national plan to support HIV laboratory services. It

also serves as the National Reference Laboratory for the country.

In 2008, EHNRI provided national leadership in strategic planning, laboratory policies, guidelines, standard

operating procedures (SOPs), training, integrated services and testing. The activities are focused on quality

assurance programs, training, referral diagnosis, establishing tiered laboratory services, and referral

linkages. EHNRI supported improvement of laboratory services for the National HIV surveillance program,

development of standard training curricula, training of laboratory personnel in HIV testing and treatment

monitoring, and evaluating of diagnostic technologies. The DNA PCR-based early infant diagnosis of HIV is

expanded to six regional reference laboratories. Regional reference testing services were initiated. EHNRI

worked closely with CDC Ethiopia to maximize support, especially to implement the national quality

assurance program, including training-of-trainers (TOT) program. EHNRI also implemented laboratory

quality assurance process, including the expansion of National External Quality Assurance Scheme

program. However, several challenges still exist in ensuring a sustainable laboratory quality assurance

program including expansion of an integrated EQA programs to more testing sites, implementation of the

WHO checklist or guidelines on accreditation for the different tiered laboratory levels and standardization of

tests and testing platforms across the laboratory network.

The FY09 activity plan will focus mainly on the continuation and expansion of FY08 programmatic areas:

quality assurance programs, training, diagnosis, and strengthening of tiered laboratory services. EHNRI will

continue supporting the strengthening of laboratory standards and will work closely with the regional

laboratories as sub-partners. EHNRI will ensure the implementation of quality-assured tiered laboratory

services from health center to district hospitals, from district to zonal/regional hospitals, and then to

reference laboratories. Regional laboratories will support routine quality assurance and control plan for

voluntary counseling and testing (VCT), diagnosis of opportunistic infections (OI), and laboratory monitoring

of ART at hospitals and health centers.

In FY09, the External Quality Assurance Program established in 52 regional and hospital sites will be

strengthened and the program will be expanded to 131 health networks. In addition to the current tests

(hematology, chemistry, CD4, HIV serology, and molecular diagnostics, DNA-PCR based early infant

diagnosis and viral load), TB and malaria smear microscopy, STI and OI diagnosis will be included in order

to make EQA program comprehensive. EHNRI in collaboration with the regional laboratories will support

strengthening of the Regional External Quality Assessment Schemes (REQAS) including preparation of

proficiency testing (PT) panels for rapid HIV testing. The dried tube spot (DTS) method will be implemented

in all facilities that are enrolled in HIV serology EQA program.

Quality control materials (proficiency panel) will be distributed to the sites thrice annually. External quality

assessment, including site visit reports and proficiency panel test results will be regularly communicated to

sites. EHNRI will develop guidance and will put a sustainable system in place for logistic management of

EQA including but not limited to panel distribution, collection of results and dissemination.

EHNRI, in partnership with CDC and PEPFAR implementing partners, will continue its training activities,

place higher emphasis on TOT of laboratory personnel in: HIV rapid diagnosis; monitoring of ARV therapy;

maintenance of laboratory equipment; laboratory quality management systems; tuberculosis (TB) and OI

diagnosis; and HIV surveillance. EHNRI will ensure that standardized training modules are used for regional

and site-level training programs supported by Regional Reference laboratories and implementing partners

As part of improving quality of services, EHNRI will strengthen the laboratory monitoring and evaluation

activities. A monitoring and evaluation system will be implemented for the effectiveness of EQA, referral

testing and in-service training and continuous quality improvement process in general. EHNRI, in

collaboration with CDC, will strengthen the laboratory monitoring and evaluation activities including, revising

and standardizing recording and reporting forms, registers/logbooks and reporting forms and ensuring

implementation at all sites.

With technical assistance from PEFPAR Ethiopia, EHNRI will support and ensure that National Reference

laboratory is accredited and will prepare regional and hospital laboratories for accreditation. EHNRI will

ensure the implementation of the Maputo declaration: standardization of testing platforms; standardization

of testing across the tier; and integration of laboratory services. EHNRI will closely work and coordinate

activities with regional laboratories, CDC, and implementing partners to strengthen the laboratory system as

per the national laboratory plan and to improve the standards of clinical laboratories. Additionally, EHNRI

will work with partners to implement the WHO checklist/guidelines for accreditation of regional, district and

health center laboratories.

EHNRI will continue supporting eight regional laboratories (Addis Ababa, Adama, Nekmet, Bahir-Dar,

Dessie, Awassa, Mekele and Harar) and the regional hospital laboratories that serve as reference

laboratories in emerging regional states to strengthen the overall quality of laboratory services. EHNRI will

disburse up to 50% of the total budget to laboratories for regional implementation of EQA program regional

training, site supervision and monitoring services and regional capacity development including program

management support. Regional laboratories will continue reporting their activities to EHNRI quarterly.

Activity Narrative: EHNRI will monitor and evaluate the performance of the sub-partners and will ensure regional capacity

developed for long term sustainability

New/Continuing Activity: Continuing Activity

Continuing Activity: 16654

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16654 5610.08 HHS/Centers for Ethiopian Health 7490 673.08 Expansion of $2,100,000

Disease Control & and Nutrition HIV/AIDS/STI/T

Prevention Research Institute B Surveillance

and Laboratory

Activities in the

FDRE

10459 5610.07 HHS/Centers for Ethiopian Health 5493 673.07 $1,500,000

Disease Control & and Nutrition

Prevention Research Institute

5610 5610.06 HHS/Centers for Ethiopian Health 3771 673.06 $800,000

Disease Control & and Nutrition

Prevention Research Institute

Table 3.3.16:

Funding for Strategic Information (HVSI): $1,200,000

Supporting the National HIV/AIDS/STI Surveillance System

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

The Ethiopian Health and Nutrition Research Institute (EHNRI) will continue to serve as the national lead

responsible for all HIV and related surveillance, and will continue to coordinate and finance the regional

Health Bureau's to help them support the related activities. In COP08, EHNRI produced and disseminated

the 7TH AIDS in Ethiopia report that was prepared mainly based on the results of the 2007 round of ANC

based HIV surveillance that involved the participation of ANC providing centers located in 108 of the health

facilities in the country. Support was also provided to all the preparatory works for the 2009 round of ANC

based HIV surveillance including for the selection of additional sites, capacity assessment of existing sites

and the conduct of national and regional review and planning meetings. Guidelines were developed,

finalized, and piloted for TB/HIV and HIV surveillance among blood donors and among commercial sex

workers. Sites for the conduct of TB/HIV and HIV surveillance among blood donors were selected by the

close collaboration between and among EHNRI regional health bureaus and the Ethiopian Red Cross

Society.

Data collection for the 2009 round ANC-based, sentinel- HIV surveillance activities will be supported in all

108 existing sites. Additional rural sites will be identified to increase the representativeness of the data and

assist in producing more valid local HIV estimates and improve the data quality. Over 1000 health workers

drawn from all sentinel sites for the ANC based HIV surveillance will be trained through regional trainers

that will be trained as trainers of trainee (TOT) at the national level. Support will also be continued to other

surveillance activities including: data collection, sample transport, provision of test kits, and other

supplies/equipments to be used by sites. Support will also be provided for supervisory visits and national

and regional review workshops. Dissemination of the ANC based HIV surveillance findings will also be

supported by PEPFAR.

]Support for non ANC-based HIV surveillance systems including TB/HIV surveillance and HIV surveillance

among blood donors will be continued. Activities related to review of the manuals; provision of relevant

trainings, data collection, processing and dissemination will be supported.

Preliminary findings of a study that was conducted to look at the prevalence of HIV and STIs and associated

risk behaviors among Most at Risk Population (MARPs) in Amhara region (official results to be released by

Amhara Health Bureau and HAPCO soon) has shown that some locally relevant MARPs may be driving the

HIV epidemic in the region. The importance of such surveillance programs/studies is now becoming

increasingly important. This is so because the low level generalized HIV epidemic in Ethiopia is more likely

to be driven by factors among locally relevant MARPs. The information currently available on MARPS is

very limited. As the trends of infection and behaviors in these population groups need to be more reliably

and consistently estimated, PEPFAR Ethiopia will continue its support for the design and implementation of

surveillance systems that consistently generate, analyze, and disseminate information that can be used for

making programmatic and policy decisions. In FY09, surveillance systems that monitor levels of HIV

infection and risk behaviors among commercial sex workers will be strengthened and implemented.

Moreover, surveillance systems that monitor levels of HIV infection and risk behaviors among mobile

population and uniformed services will be developed and piloted.

EHNRI will also undertake an HIV surveillance activity (BED assay) to estimate the extent of new HIV

infections in the country. Appropriate protocols related to this will be developed and stored blood samples

collected in previous ANC based HIV surveillance rounds as well as those collected in the 2009 round will

be used for the testing. The results of this assay will help to corroborate the data from other HIV

surveillance sources and to identify trends in new HIV infections.

PEPFAR Ethiopia will also support EHNRI to build the capacity of regions for undertaking surveillance

activities and enable them to better understand HIV surveillance data for decision making. Hence training of

regional and central staff in electronic data processing using EPI info, GIS and other analysis softwares will

be provided. Key surveillance staff will also participate in experience sharing workshops and trainings

abroad and in country to address the challenges and share best practices and lessons learned. (Eight staff

for abroad and 15-20 in country experience sharing events).

COP08 NARRATIVE

The Federal Ministry of Health (MOH) began work on strengthening and supporting the National

HIV/AIDS/STI (sexually transmitted infections) Surveillance system in 2002. Activities have been ongoing;

however, implementation of activities was slowed in the second half of FY06 and first quarter of FY07 due

to organizational changes at the Ministry, at which time the responsibility for implementing and coordinating

HIV/AIDS/STI/TB (tuberculosis) surveillance was given to the Ethiopian Health and Nutrition Institute

(EHNRI). Since then, PEPFAR Ethiopia has been heavily involved in supporting EHNRI in the facilitation

and implementation of most surveillance activities; however, recently EHNRI reorganized itself and has

been better able to handle these activities.

Funds from FY07 have been used for building the capacities of the EHNRI and regional health bureaus

(RHB) to enable them to extend their support to zonal health departments (ZHD), district health desks, and

health facilities that are directly involved and benefiting from HIV/AIDS, TB/ HIV and STI surveillance

programs. Moreover, in FY07, EHNRI, with PEPFAR Ethiopia funding, extended support to RHB to allow

them to support 19 additional health facilities as sites for antenatal clinic (ANC)-based HIV surveillance.

EHNRI will train site staff in the collection, compilation, and reporting of HIV case surveillance data.

IN FY07, communication between and among all the surveillance partners was also enhanced. The

capacity of RHB to provide supportive supervision to all the health facilities involved in surveillance activities

was strengthened. EHNRI, in collaboration with CDC and other relevant partners, also provided support to

RHB to conduct their annual surveillance planning and review meetings with their respective surveillance-

site staff.

RHB, ZHD, district health desks, and health facilities were all supported through EHNRI in their preparations

Activity Narrative: for the planning and execution of the 2007 National HIV/AIDS/STI surveillance activities. EHNRI provided

them with technical guidance in the selection of staff for trainings, selection and preparation of sites, data

and sample collection, sample transportation, supportive supervision, and data management.

In FY08, preparatory work for the 2009 round of ANC-based, sentinel-site HIV surveillance activities will

commence. These activities include: assessment of sites; training of site-level ANC clinic and laboratory

staff; procurement of test kits and other supplies to be used by sites; and conduct of national and regional

review workshops.

PEPFAR will also support EHNRI in the initiation of several new types of surveillance, including HIV case,

STI, and TB/HIV surveillance. These programs will be implemented based on the guidelines developed by

EHNRI and PEPFAR over the past several years. EHNRI will work this year toward building its own capacity

and the capacity of regional laboratories, RHB, and health facilities involved in established and new

surveillance programs.

PEPFAR will also support EHNRI to build a national drug-resistance surveillance system. This will help

PEPFAR partners and the Government of Ethiopia to ensure the generation, analysis, and use of

information that can help develop and maintain effective strategies for ARV use. This activity will help to

produce the evidence to guide national the HIV/AIDS treatment plan and other measures to sustain the

effectiveness of ART among newly infected patients.

Finally, PEPFAR will also support EHNRI to design and implement an HIV/AIDS/STI surveillance system

using selected sites that provide HIV/AIDS/STI services to the most-at-risk populations (MARPs), especially

to commercial sex workers. This will help PEPFAR and the country to generate information that can be

used to guide HIV/AIDS/STI/ programs for MARPs, given the nature of the low-level, generalized HIV

epidemic in the country.

New/Continuing Activity: Continuing Activity

Continuing Activity: 18050

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

18050 18050.08 HHS/Centers for Ethiopian Health 7490 673.08 Expansion of $1,200,000

Disease Control & and Nutrition HIV/AIDS/STI/T

Prevention Research Institute B Surveillance

and Laboratory

Activities in the

FDRE

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $150,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.17:

Subpartners Total: $0
Regional Health Bureaus: NA
Cross Cutting Budget Categories and Known Amounts Total: $150,000
Human Resources for Health $150,000