Detailed Mechanism Funding and Narrative

Years of mechanism: 2010 2011 2012 2013 2014

Details for Mechanism ID: 11708
Country/Region: Botswana
Year: 2013
Main Partner: U.S. Centers for Disease Control and Prevention
Main Partner Program: NA
Organizational Type: Implementing Agency
Funding Agency: HHS/CDC
Total Funding: $175,000

There are differences in TB and HIV prevalence and population dynamics between the Western and Southern areas of Botswana which offer a unique opportunity for the study and comparison of the transmission dynamics of TB and MDR TB in stable/aggregated and dynamic/open populations and determine the effect of HIV on these transmission dynamics. Molecular epidemiology provides unique opportunities to understand crucial aspects of the transmission dynamics of TB in the community that could lead to successful public health interventions.

This Molecular Epidemiology Program will be a collaborative project between the Government of Botswana, the Botswana-University of Pennsylvania Partnership and CDC. We will combine classical epidemiologic methods and molecular epidemiology to determine the transmission dynamics of TB in closed/clustered (Western region) and open/dynamic (Southern region) populations in Botswana and the effect of HIV infection and drug-resistance on TB transmission in these settings. Mathematical models of TB epidemics using real-world data generated will be developed to measure the effectiveness of different public health interventions to interfere with TB transmission and to guide the Ministry of Health to direct infection control measures towards hotspots of TB transmission in the country.

Funding for Laboratory Infrastructure (HLAB): $75,000

The Genotyping Lab is a CDC owned lab that will support CDC studies and protocol and also serve as a training facility for Ministry of Health (MOH) Laboratory staff. The objective is to assist MOH to find alternative, cheaper and more affordable techniques for monitoring patients on ARVs. The fund will be used to procure service and maintenance contracts for equipment and for procurement of reagents and consumbles.

Funding for Prevention: HIV Testing and Counseling (HVCT): $100,000

This is a CDC centrally funded cooperative agreement with Emory University to provide south-to-south technical assistance on couples HIV testing and counseling (CHTC). The Rwanda Zambia HIV Research group has been providing CHTC since 1986 and has also succesfully scaled up these services in both Rwanda and Zambia. Through this coag, they are able to share best practices and lessons learned with other countries seeking to initiate and/or scale-up CHTC programs in antenatal, HIV care and treatment, TB and other settings.

The Government of Botswana is in the process of finalizing the National Couple HIV counseling & testing strategy and an implementation plan to guide the scale up of CHCT serivces in country. Through the Center of Excellence mechanism, Botswana will receive direct technical assistance in couple testin from Emory and support to organize and roll out Couple HIV counseling in a diverse variety of setting in the country. The HTC TWG at CDC HQ will work with the country team to develop specific set of TA deliveries that Emory would be working on.

Cross Cutting Budget Categories and Known Amounts Total: $100,000
Gender: Gender Equality $25,000
Human Resources for Health $75,000
Key Issues Identified in Mechanism
Increase gender equity in HIV prevention, care, treatment and support