Detailed Mechanism Funding and Narrative

Years of mechanism: 2007 2008 2009

Details for Mechanism ID: 5263
Country/Region: Zambia
Year: 2009
Main Partner: Vanderbilt University
Main Partner Program: NA
Organizational Type: University
Funding Agency: HHS/NIH
Total Funding: $240,000

Funding for Health Systems Strengthening (OHSS): $240,000

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

?Highlights on progress made in FY 2008

Summary: The Vanderbilt University-University of Alabama at Birmingham AIDS International Training and

Research Program (VU-UAB AITRP; 5-D43-TW00135-10), led by Dr. Sten Vermund, has played an

important role in the development and sustainability of research capacity in Zambia. Twenty-nine Zambians

have received Masters of Public Health (MPH) from the University of Alabama at Birmingham or Masters in

Science (MSc) from the London School of Hygiene and Tropical Medicine; all have returned to work in

Zambia. Over 500 Zambians have been trained in-country and over 40 Zambians have been trained in

short courses at UAB. The program has been instrumental in strengthening the ability of Zambian

investigators to take part in large-scale public health evaluation, service, and research projects, take on

leadership positions in initiatives such as PEPFAR, and apply for additional research and public health

service funding. VU-UAB AITRP in-country trainees will continue to sustain the current service, research,

and training efforts, even once the AITRP training funds are exhausted because considerable attention has

been given to sustainability.

Since the program's implementation in 1998, there has been a high demand for additional primary training

as well as continuing education for public health professionals and to continue building institutional capacity

in Zambia. Since the beginning of its collaboration with the University of Zambia (UNZA) and the University

Teaching Hospital (UTH), the VU-UAB AITRP has continued to work closely with these institutions and the

Vanderbilt Institute for Global Health and the UAB Sparkman Center for Global Health to provide

biostatistics and research methods training at the UNZA, to build medical informatics capacity, and to

improve the overall climate for research with donated journals, guest seminars, and research consultation.

Our goal is to develop Zambian clinical investigators who can be leaders in independent investigation,

including research through manuscript submission and grant writing. This is not at all redundant to our

AITRP, but is complementary. Our resources do not support both our long term trainees and continued in-

country programs of this magnitude. Happily, the CDC-Zambia office concurs with this need and has

indicated support for this AITRP supplement to support the ongoing in-country mentorship and training work

outlined below.

1. Specific Aims: 1) Train a new generation of HIV/AIDS research leaders in our partner nations, allied

closely with institutions that are superbly placed to provide national and regional leadership in HIV/AIDS

prevention and care research, emphasizing both physician and nurse-scientist training. 2) Promote the

initiation of new HIV- related research that complements and facilitates existing international research

endeavors between US and foreign investigators and builds long-term collaborative relationships among

international scientists themselves. 3) Track and document the long-term impact of training on Trainee

careers, Research capacity of home institutions and Impact of conducted research at institutional, regional,

national, and global levels.

I.The FY 2009 funding will support the following three activities:

A. Master's of Medicine (MMed) Capacity Building: The UNZA MMed program is a degree taken in parallel

with post-graduate residency training. This degree involved a research project and a full MMed thesis. In

Dr. Vermund's ten-year experience of working in Zambia, the program did not meet its didactic goals in

perhaps 90% of its graduates. This is demonstrated in the overall poor methodology used for MMed

research projects and the inability to get MMed projects published. We aim to hire a Zambian-based

consultant to mentor MMed students during the last six months of the project. The mentor will be a senior

masters-level researcher (MPH or MMed preferred) with expertise in research methods and biostatistics.

We will consult with Dr. K. Bowa, MSc, BSC, MBChB, M Med, FRCS(Glasgow), FCS (ECSA), Assistant

Dean of Postgraduate Affairs at UNZA in the consultant selection process. The mentor will guide the MMed

students through their research design, implementation, analysis, publication of results, and grant

submissions. MMed Tutoring will also be provided by Zambians with masters-level training from universities

such as UAB, Emory, LSHTM, University of Nebraska, and the University of Miami. Advanced MMed

students will be invited to participate in the training outlined in Section III B. Research awards ($2,500) will

be provided to 12 MMed students for their HIV-related research projects. Applications will be vetted and

reviewed by Dr. Vermund, Dr. Kristensen, and three UNZA faculty members.

B. Short-term In-country Training: The Vanderbilt-UAB AITRP has conducted three workshops (May 2005,

April 2006, and January 2008) in Zambia sponsored by FIC-NICHD-CDC entitled, "Advanced Short Course

in Proposal Writing and Manuscript Preparation". The short-courses were focused on upgrading

HIV/AIDS/TB/STI-related research capacity among already-trained, experienced Zambian health

professionals. Many of the trainees have received MPH or MSc degrees from UAB, LSHTM, or other

universities, while others have completed MPH or MMed training at the University of Zambia. All 73

trainees were in positions of academic authority, government service, or non-governmental activity in which

they have opportunity to engage in HIV/AIDS/TB/STI-related research. The most recent short-course in

January 2008 included in-depth training and small group mentorship solely focused on manuscript writing.

Out of the 28 trainees from the 2008 training: 12 manuscripts have been submitted, two are currently in

press, and 22 are in development.

We intend to conduct two short courses in scientific writing in 2009 to support HIV/AIDS-related research

efforts in-country. We will utilize local expertise and other fiscal support as we have done in the past.

Vanderbilt, UAB, and UNZA faculty/staff will lead the short-course training program. We recommend a

maximum of 25 trainees per workshop to enhance the contacts between trainers and trainees.

C. UNZA MPH Curriculum Development: The Department of Community Medicine at UNZA is one of the

departments in the School of Medicine (SoM) that runs several undergraduate and postgraduate courses in

public health. In the MPH program, the department runs, among other modules, the Basic Epidemiology &

Biostatistics, Health System Research and Management modules. The main strategy of the project is to

create a demand-driven graduate public health education program with a well-defined and clear mission to

increase the number of trained public health professionals with specialization in Epidemiology and

Activity Narrative: Biostatistics in Zambia. Our AITRP Co-Investigator Dr. Sybille Kristensen and the UAB administrative staff

will assist our partners at UNZA in developing new courses and updating existing courses. Support will be

provided for four UNZA faculty (MMed and MPH) to attend a month-long training at The Perinatal HIV

Research Unit (PHRU), a research unit of the University of the Witwatersrand in Soweto, South Africa.

UNZA faculty will be provided first-hand training in not only prevention of mother to child transmission but on

many different aspects of HIV prevention, treatment and care including medical and social research.

New/Continuing Activity: Continuing Activity

Continuing Activity: 15621

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15621 9787.08 HHS/National Vanderbilt 7203 5263.08 VU-UAB AITRP $240,000

Institutes of Health University

9787 9787.07 HHS/National Vanderbilt 5263 5263.07 VU-UAB AITRP $50,000

Institutes of Health University

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $240,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.18:

Cross Cutting Budget Categories and Known Amounts Total: $240,000
Human Resources for Health $240,000