Detailed Mechanism Funding and Narrative

Years of mechanism: 2010 2011

Details for Mechanism ID: 12251
Country/Region: Tanzania
Year: 2010
Main Partner: Not Available
Main Partner Program: NA
Organizational Type: NGO
Funding Agency: HHS/HRSA
Total Funding: $0

Goals and Objectives

Routine monitoring of HIV transmission from mothers to their infants gives direct information on the quality of PMTCT programs and number of infections averted. It can serve as feedback for program improvement but also for projection of the burden of disease and for procurement forecasting. In order to monitor the ongoing PMTCT program expansion and quality improvement, we propose to establish 15 sites for HIV-transmission monitoring. All children <1month seen at these sites will be routinely tested for HIV in a standardized way using DNA PCR. Sites identified are already operational, but do not yet test in a standardized way. The activity will largely involve data abstraction at 'well baby clinics'.

Objectives

1. To capture the HIV-exposure status of all children born to HIV+ mothers using Mother-Child Follow-up Registers at the 15 sites.

2. To determine, using Mother-Child Follow-up Registers, the PMTCT intervention received by the mother-child pairs.

3. To establish the HIV-infection status for each HIV-exposed child, using DBS DNA PCR technology.

4. To calculate the mother-to-child transmission rate of HIV at study sites.

5. To compare the effectiveness of different PMTCT interventions at the sites.

Contributions to Health Systems Strengthening

Routine monitoring as part of program management and service provision serves as direct feedback and motivation for health care workers and decision makers. This is true especially in settings where the effectiveness of PMTCT interventions is doubted by many professionals and mothers are counseled accordingly. We expect that timely feedback on quality of interventions will improve motivation and effectiveness of health care staff at facilities as well as at planning level.

Cross-cutting programs and key issues

Establishment of this monitoring system will directly provide information on the effectiveness of PMTCT programs over time, especially in the light of the ongoing PMTCT initiative by OGAC and the Global Fund. However, further expansion of this monitoring platform could provide follow up information on a range of services received during antenatal care and labor and delivery and related to maternal and child health.

IM Strategy to become more cost-efficient over time

Best strategies and most cost-effective interventions will be identified and programs can be directed strategically in order to achieve maximum benefit.

Geographic coverage and target populations

The study will be conducted at 15 sites in 3 regions.

The target population will be all HIV+ pregnant women and their children.

How IM links to PF goals

Goal 1 of the PF is on maintenance and scale-up of quality services. Routine monitoring of HIV-transmission will directly inform decision makers on strategies for best quality scale up and maintenance of programs.

Goal 2 of the PF focuses on prevention, including PMTCT efforts. This project is in line with this goal, as it will directly measure infections averted.

Goal 4 of the PF addresses the HIV drug and commodity supply. Through monitoring transmission and interventions received, CDC TZ and its partners will be better able to better forecast the quantities of HIV drugs required for prophylactic interventions as well as the needs for pediatric HIV care and treatment. Determining which prophylaxis is the most effective will also have implications for future drug and commodity supply calculations.

Goal 6 of the PF aims to ensure evidence-based decision making and strategic planning. The results of this project will feed directly into future decision-making and strategic planning for PMTCT interventions.

M&E Plans

The objectives of this project reflect M&E objectives for PMTCT programming. The results will serve as an ongoing monitoring of the effectiveness of various PMTCT interventions as well as the level of coverage of PMTCT interventions .

Funding for Biomedical Prevention: Prevention of Mother to Child Transmission (MTCT): $0

Routine monitoring of HIV transmission from mothers to their infants gives direct information on the quality of PMTCT programs and number of infections averted. It can serve as feedback for program improvement but also for projection of the burden of disease and for procurement forecasting. In order to monitor the ongoing PMTCT program expansion and quality improvement, we propose to establish 15 sites for HIV-transmission monitoring. All children <1month seen at these sites will be routinely tested for HIV in a standardized way using DNA PCR. Sites identified are already operational, but do not yet test in a standardized way. The activity will largely involve data abstraction at 'well baby clinics'.

Objectives

1. To capture the HIV-exposure status of all children born to HIV+ mothers using Mother-Child Follow-up Registers at the 15 sites.

2. To determine, using Mother-Child Follow-up Registers, the PMTCT intervention received by the mother-child pairs.

3. To establish the HIV-infection status for each HIV-exposed child, using DBS DNA PCR technology.

4. To calculate the mother-to-child transmission rate of HIV at study sites.

5. To compare the effectiveness of different PMTCT interventions at the sites.

Subpartners Total: $0
To Be Determined: NA