Detailed Mechanism Funding and Narrative

Years of mechanism: 2008 2009

Details for Mechanism ID: 3640
Country/Region: Mozambique
Year: 2009
Main Partner: To Be Determined
Main Partner Program: NA
Organizational Type: Implementing Agency
Funding Agency: HHS/CDC
Total Funding: $0

Funding for Biomedical Prevention: Prevention of Mother to Child Transmission (MTCT): $0

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

(1) HIV and malaria in pregnancy component reprogrammed to JHPIEGO in FY08; no new funding for FY09

(2) Central level support component to be reprogrammed for implementation in FY09

April08 Reprogramming Changes: This reprogramming request is to split the TBD, with $135,000 for HIV

and malaria in pregnancy activities to JHPIEGO.

This activity, which is new in the PMTCT program area, represents initial steps for strengthening the

linkages between HIV and malaria prevention, diagnosis and treatment services. Experience from this

activity can be used to create the foundation for improved linkages between HIV and malaria components.

Objectives: A) Strengthen the linkages between HIV and malaria prevention, diagnosis and treatment

services; B) Improve coordination of PMTCT and malaria mitigation activities.

Main Activities will be: (1) Complete HIV and malaria health services assessment, including documentation

of current malaria and HIV prevention, diagnosis and treatment services conducted in PMTCT settings in

selected provinces, with additional focus on linkages between services; (2) Complete analysis of

assessment findings, develop and disseminate recommendations; (3) Develop updated service delivery

guidelines for malaria, HIV/AIDS, and reproductive health; (4) Based upon results of assessment, create

plan for next steps for development/adaptation and pilot test of materials and recommendations for

strengthening of linkages between malaria and HIV prevention, diagnosis and treatment services.

This activity is composed of two distinct pieces: the first focusing on HIV and malaria in pregnancy

[$135,000], and the second focusing on central-level support for PMTCT policy development, including

mother support groups and integration with child health [$203,000].

HIV and malaria in pregnancy

It is well-known that malaria and HIV are devastating global health problems. Less is known about the

interaction of the diseases or treatment choices for co-infected individuals; however, the current information

reveals a very serious public health problem given the wide geographic overlap of the diseases in sub-

Saharan Africa. HIV and malaria are highly endemic in Mozambique. HIV prevalence is 16.2%, and more

than 90% of the population is exposed to malaria. Malaria is the largest single cause of mortality in

hospitals: it is responsible for over 40% of outpatient visits and for 30% of recorded hospital deaths. The

population is thus not only at severe risk of ill-effects of each disease, but for co-infection by both of them.

Pregnant women are especially vulnerable to these diseases. Malaria during pregnancy increases the risk

of maternal anemia, spontaneous abortion, still birth, low birth weight, and neonatal death. It is responsible

for the death of approximately 10,000 African women and 200,000 infants each year.

This activity, which is new in the PMTCT program area, represents initial steps for strengthening the

linkages between HIV and malaria prevention, diagnosis and treatment services. Experience from this

activity can be used to create the foundation for improved linkages between HIV and malaria components.

Objectives: A) Strengthen the linkages between HIV and malaria prevention, diagnosis and treatment

services; B) Improve coordination of PMTCT and malaria mitigation activities.

Main Activities will be: (1) Complete HIV and malaria health services assessment, including documentation

of current malaria and HIV prevention, diagnosis and treatment services conducted in PMTCT settings in

selected provinces, with additional focus on linkages between services; (2) Complete analysis of

assessment findings, develop and disseminate recommendations; (3) Develop updated service delivery

guidelines for malaria, HIV/AIDS, and reproductive health; (4) Based upon results of assessment, create

plan for next steps for development/adaptation and pilot test of materials and recommendations for

strengthening of linkages between malaria and HIV prevention, diagnosis and treatment services.

The activity described so far will provide a foundation for future revision of training materials and service

delivery guidelines beyond the PMTCT setting, with latest evidence relating to the interaction between HIV

& Malaria.

Central-level PMTCT support

This is a new activity designed to strengthen national PMTCT leadership and guidance by creating

opportunities with a TBD partner with central-level influence and experience in Mozambique, such as

UNICEF or other potential applicants. The TBD partner will be in a unique position to influence MOH policy

at central level, including finalization of outstanding PMTCT norms and standards, as well as a systematic

approach to integrating PMTCT and child health (IMCI) activities, thereby creating a stronger link between

PMTCT and child survival efforts.

Key activities will include A) Support for central-level finalization and dissemination of PMTCT norms and

standards; B) Support for coordination of PMTCT and child health integration, including IMCI; C)

Collaborate with I-TECH in development and implementation of mother support groups for PMTCT.

Coordination between stakeholders started in FY07 with planning for a support group assessment activity,

and FY08 activities will include development of a standard model, pilot phase, and implementation.

New/Continuing Activity: Continuing Activity

Continuing Activity: 16309

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

16309 16309.08 HHS/Centers for To Be Determined 6412 3640.08 TBD

Disease Control & Cooperative

Prevention Agreement

Table 3.3.01:

Funding for Sexual Prevention: Abstinence/Be Faithful (HVAB): $0

This is a new activity. The Families Matter! Program (FMP) is an evidence-based, parent focused

intervention designed to promote positive parenting and effective parent-child communication about

abstinence, sexuality, decision-making and sexual risk reduction for parents of 9-12 year olds. FMP is an

adaptation of the US-based "Parents Matter" curriculum which CDC has implemented and evaluated in the

US with various partners. This community-based family prevention program strives to foster enhanced

protective parenting practices and promote parent-child discussions about abstinence, sexuality, decision-

making and sexual risk reduction. The ultimate goal of FMP is to support sexual abstinence and reduce

sexual risk behaviors among adolescents, including delayed onset of sexual debut, by giving parents tools

to deliver primary prevention to their children.

FY09 funds will be used to conduct a formative assessment to culturally adapt and pilot test the program

materials that are currently being used in Kisumu, Kenya. We propose to implement the FMP in the

province of Zambézia and the Beira and Maputo corridors, where HIV prevalence among women aged 15 -

14 years old is high and above the national prevalence with some surveillance sites showing rates close to

20% - 25% or more in 2007. The 2003 DHS data suggest that high HIV prevalence in Zambézia and Beira

corridor may be associated with factors such as early sexual debut (15.7% vs 16.1% nationally) and high

level of women engaged in intergenerational sexual relations. In Maputo and Gaza provinces (Maputo

corridor) HIV incidence continues to increase and have high levels of reported risk behaviors among young

women and men like multiple sex partnerships and low level of condom use. Activities promoting abstinence

and delay of sexual debut in young people have been key in a multi-component intervention program to

improve adolescents' sexual and reproductive health in areas such as those proposed for Mozambique. A

preliminary analysis of an assessment conducted in Kenya 15 months post-intervention, found sustained

positive effect in terms of parenting and communication skills reported by participants and their children

separately.

Following the formative assessment and material adaptation, the TBD partner implementing FMP will train

facilitators to deliver the five consecutive, three-hour sessions for parents and caregivers. The intervention

curriculum focuses on: raising awareness about the sexual risks many teens face today; encouraging

general parenting practices (e.g., relationship building, monitoring) that increases the likelihood that children

will not engage in risky sexual behaviors; and improving parents' ability to effectively communicate with their

children about abstinence, sexuality and sexual risk reduction. An additional emphasis will be placed on

training parents to address the role of gender-based norms in adolescent sexual decision-making and risks

associated with transgenerational sex for girls. FMP uses a mixture of structured learning experiences,

discussion, audiotapes, role plays, and group exercises. In addition, a combination of both verbal and

visual instruction techniques was incorporated in the program in an attempt to address auditory versus

visual learning preferences.

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Gender

* Addressing male norms and behaviors

* Reducing violence and coercion

Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.02:

Funding for Sexual Prevention: Other Sexual Prevention (HVOP): $0

Alcohol consumption and its consequences together with HIV/AIDS are major public health burdens in

many parts of the world. There is overlap between persons at risk for alcohol-related problems and

individuals at risk for HIV infection. Regardless of the level consumed, alcohol is likely to influence the

health status and behaviors of persons infected with HIV and those whose behaviors place them at risk for

acquiring the virus.

As HIV/AIDS research becomes more focused, there is growing evidence that alcohol consumption may

play an important role in sexual transmission, susceptibility to infection, and progression of HIV disease. In

addition to being a possible risk factor in the transmission and progression of HIV disease, alcohol misuse is

likely to impact adherence to complex HIV medication regimens and to physician advice.

There is a growing evidence that alcohol consumption in African countries is becoming an important public

health problem and year 2000 estimates from World Health Organization (WHO), 2004) indicate that the

eastern and southern Africa have the highest consumption of alcohol per drinker in the world associated

with the prevalence of hazardous drinking patterns.

It is therefore important to conduct an assessment which seeks to clarify the role of alcohol in HIV

transmission and disease progression, and to develop and test preventive interventions which both reduce

the risk of alcohol-related HIV transmission and improve the treatment of HIV infected alcohol abusing

and/or alcohol dependent individuals.

To date, there are no data on the magnitude and patterns of alcohol consumption in Mozambique that can

be used for planning HIV prevention and control activities. In order to establish effective interventions that

address the role of alcohol in HIV transmission and control, there is a need to evaluate the current pattern of

alcohol consumption and explore related sexual risks contributing to HIV transmission in the country. In

April 2006, the Mozambique's National AIDS Council convened the first meeting in the country to start

addressing alcohol consumption, where besides generalized alcohol consumption different stakeholders

expressed their concerns regarding high level of consumption of locally brewed beverages mainly in peri-

urban and rural areas. It has however stressed that the real magnitude of this problem as well as the

associated HIV risk behaviors are unknown.

In order to start establishing effective interventions that address the role of alcohol in HIV transmission and

control, there is a need to evaluate the current pattern of alcohol consumption and substance abuse, and

explore related sexual risks contributing to HIV transmission in the country.

New/Continuing Activity: New Activity

Continuing Activity:

Table 3.3.03:

Funding for Sexual Prevention: Other Sexual Prevention (HVOP): $0

This is a new activity in that it is organized as its own separate activity, but is a continuation of the

subactivity listed as Activity 4993.08 in COP 08.

Mozambique has not yet implemented a round of Behavioral Surveillance. A pre-formative project was

conducted in FY08 to help the Government of Mozambique and other stakeholders to identify and prioritize

key risk groups (Phase 1). Current groups proposed for inclusion in BSS include female commercial sex

workers, young women involved in transactional sex, miners and their partners, and long distance truck

drivers. This will be followed by the formative phase to develop plans and protocol for BSS+

implementation (Phase 2). Ultimately 3-4 groups will be included in the BSS; final selection of these groups

will be dependent on Phase 2 activities including an assessment of feasibility of inclusion of each group.

Phase 2 will be followed by Phase 3, the survey implementation phase. Currently it is planned that the

survey will include a biomarker to estimate HIV prevalence for these groups. Funds will be used for

technical assistance needed to plan and implement Phase III, required commodities and lab supplies for

BSS implementation, contracting of local field teams for data collection and entry, and technical assistance

for data analysis and dissemination.

Some funds were allocated for BSS with 07 Plus-up monies ($422,000) and COP 08 monies ($578,000).

However, based on the experiences of other countries implementing BSS (including Angola), and that fact

that some characteristics of Mozambique including limited physical infrastructure compounded with the

need to coordinate a complex survey in Portuguese, we anticipate that a minimum of $2.225 million will be

needed to implement a survey that includes four groups.

$450,000 is being requested in COP 09 through the Other Prevention program area to support this activity.

New/Continuing Activity: New Activity

Continuing Activity:

Table 3.3.03:

Funding for Sexual Prevention: Other Sexual Prevention (HVOP): $0

Data collected in the United States and throughout Africa consistently demonstrates that many HIV-infected

persons continue to engage in high-risk sexual behaviors that may transmit HIV, despite knowledge of their

HIV infection. Anecdotal evidence suggests that the same is true in Mozambique; however, there are only

limited efforts implementing prevention techniques in HIV care settings and capitalizing upon provider

interactions with HIV-infected patients in order to stop the transmission of HIV.

These reprogrammed funds ($500,000) will be used to scale-up and expand existing, pilot Postive

Prevention (PP) efforts in Mozambique. The goals of the PP intervention are to prevent morbidity among

persons living with HIV/AIDS (PLHA), prevent HIV transmission to sexual partners and children of PLHA,

and reduce stigma for PLHA in service settings. The PP project is targeted toward providers within clinical

and community-based sites in Mozambique to encourage them to address the prevention and care needs of

those living with HIV in Mozambique. Working under the assumption that the patient-provider relationship

contains vast opportunities to carry-out HIV transmission interventions, existing partners developed provider

and patient specific goals and objectives to track behavior changes in both populations. This includes

discussions about:

HIV risk behavior (risk reduction techniques)

Encourage partner testing

Counseling and support

How to disclose HIV to partners and family members

How to produce or maintain healthy families

Individualized prevention plans and risk reduction techniques

The TBD partner would use existing, Mozambique-specific materials developed by the University of

California at San Francisco (UCSF) to implement PP activities in high prevalence provinces of the country.

This partner and activity will complement the ongoing work of UCSF by expanding to additional provinces

and/or districts and focusing more extensively on community-based PP efforts. The focus of the program is

to provide healthcare workers at facility-based sites and PLWHA and counselors at community-based sites

with competencies, comfort and skills to discuss risk behavior, risk reduction techniques and prevention

needs, thereby decreasing HIV transmission and encourage partner and family testing.

The additional funds will be used to expand the PP program to two additional provinces, Gaza and Manica,

which have high HIV prevalence.

Deliverables and Products

Number of sites supported and activities developed in the sites and number of existing PLWHA groups

supported

Number of staff trained from Clinical Care & Treatment partners

Number of staff trained from HBC/community Care partners

Number of staff from Mozambican PLWHA Organizations or groups trained and received some mentorship

on PP with these organizations

M&E for scale -up of PP activities: (1) Routine monitoring of basic process indicators (e.g. # partners

involved, # sites, # staff trained); (2) Program evaluations (TBD, possibly annually)

Collaboration with MATRAM, by integrating PP messages in the treatment education/literacy activities

New/Continuing Activity: New Activity

Continuing Activity:

Table 3.3.03:

Funding for Treatment: Pediatric Treatment (PDTX): $0

THIS IS A NEW ACTIVITY

Until October 2008, Early Infant Diagnosis (EID) capacity was limited to a single reference laboratory (INS)

in the capital city of Maputo, in the southernmost region of the country. Testing capacity was expanded in

October 2008, when a second laboratory in the Northern region of the country was opened. Dried Blood

Spot specimens from every Province in the country are referred to one or the other of these laboratories for

testing. As a result, long delays often occur in getting test results back to health facilities for communication

to patients and follow up. To improve the timeliness and access to EID, FY09 funds will support expansion

of EID to an additional laboratory in the Central region of the country. FY09 funding to TBD-Brazilian

Partner will support a laboratory mentor for the new laboratory for one year. This laboratorian, with expertise

in DNA PCR and specimen management will support Mozambican laboratory technicians who will be

trained to perform testing. Mentor will ensure good laboratory practices are being followed, including use of

SOPs and internal quality assurance. Mentor will also facilitate participation of the laboratory in the EQA

program with INS. Mentor will monitor activities, identify problems, and seek solutions as needed. S/He will

transfer skills and knowledge and build capacity in technical staff through on the job training and coaching.

New/Continuing Activity: New Activity

Continuing Activity:

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

13208 8547.08 HHS/Centers for JHPIEGO 8784 8784.08 $1,047,000

Disease Control &

Prevention

8547 8547.07 HHS/Centers for To Be Determined 4879 3640.07 TBD

Disease Control & Cooperative

Prevention Agreement

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.11:

Funding for Testing: HIV Testing and Counseling (HVCT): $0

ACTIVITY UNCHANGED FROM FY2008 (No new funds for FY09)

This PHE activity, "The validation, acceptability and feasibility of oral fluid based rapid antibody testing in

Mozambique", was approved for inclusion in the COP. The PHE tracking ID associated with this activity is

MZ.07.0075

Continuing activity - FY 07 COP activity number: 8633 - Title: The validation, acceptability and feasibility of

oral fluid based rapid antibody testing in Mozambique.

Principal Investigators:

Cynthia Sema - National Institute of Health, Ministry of Health (MOH)

Kenete Mabjaia - Counseling and Testing (CT) Program, MOH

Project description: The purpose of this study is to evaluate the performance, acceptability and the

feasibility of two HIV 1/2 oral fluid test (Oraquick® and Calypte Advance) in Mozambique. The tests'

performance, as compared to the gold standard, will be evaluated in a first stage with specimens collected

from clients at selected Counseling and Testing (CT) centers in Maputo City and processed at the

Mozambique National Health Institute reference laboratory for HIV testing. After this validation, the test's

acceptability and feasibility will be assessed in remote areas and communities within the context of

youthfriendly

HIV/AIDS services and community-based CT (CCT).

Progress to-date: Turnover of staff at the Ministry of Health including a new CT Program Director delayed

the development of this protocol during the first year. Substantial progress has been made since new MOH

Principal Investigators have been identified, and support for development of the study protocol been

providing through USG supported consultancies and fellowships. The protocol and tools are now in final

stages and expected to be submitted for reviews in the US as well as the Mozambican Bioethics Committee

in country late September/early October 2007. An in-country working group has been formed, composed of

MOH laboratory and CT program staff, USG supported CT stakeholders (JHPIEGO, PSI and Pathfinder),

and USG technical staff. Preliminary preparations at sites selected and identification of staff to be involved

has started and will be in place for implementation once approval has been obtained.

Lessons Learned: Frequent changes and transfers of MoH personnel require constant re-briefing of new CT

personnel coming from a variety of professional backgrounds and potentially limited prior CT experience.

Recruitment for a USG study coordinator is in process and expected to be completed by end of FY07. This

staff will ensure continuity of activities, briefing of new MOH personnel and working group members, and

helping to move this activity forward without major delays in the future.

Information Dissemination Plan: Stakeholders that are also part of the MOH lead study working group will

participate in the planning and presenting of the data at meetings and conferences. Results of the study will

be disseminated to all participants including counselors in the study. Possibilities to publish results in a peer

reviewed journal will be explored.

Planned FY08 activities: The study will be comprised of two phases. The first phase will consist of a

laboratory-based evaluation of the test performance of the two oral HIV tests, i.e., its sensitivity, specificity

and predictive values. Approximately 400 HIV-positive samples will be required and will be collected at

Counseling and Testing (CT) sites in Maputo City. Two sites with high client volumes have been selected as

sites for collection of samples. Besides the oral fluid test, to be performed at the facility, whole blood

samples will collected using Dried Blood Spots (DBS) and sent to the National reference laboratory for HIV

testing. It is anticipated that this phase will take approximately 3 months. The second phase will entail taking

the test into communities with little or no access to facility-based HIV testing as well as to youth services.

Qualitative methods, specifically group interviews and semi-structured individual interviews will be

conducted in order to obtain in-depth information about community members' and youths' views regarding

rapid oral HIV testing. It is estimated that this second phase will take approximately 4 months, including the

analysis of the qualitative data collected.

Budget Justification for FY08 monies: While funding from previous years will contribute to completion of the

1st phase of this study and cover expenditures such as the procurement and importation of Oraquick® test

kits, procurement of supplies for testing and implementation of adequate biosafety measures, transport of

samples between sites and the reference laboratory, training and contracting of short-term laboratory

personnel for study-related HIV testing; funding requested for FY08 will cover costs for the second

qualitative phase such as training and contracting of interviewers for the qualitative assessment, travel and

per diems for in-country travel, short-term local contracts for transcription, translations, data entry and data

analysis.

Activity Narrative: Salary/fringe benefits: not applicable (na)

Equipment: $ 15.000

Supplies: $ 20.000

Travel: $ 30.000

Participant incentives: na

Laboratory testing: na (covered through previous years funding)

Other: $ 25.000 (Meetings and results dissemination)

Total: $90,000

New/Continuing Activity: Continuing Activity

Continuing Activity: 15737

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

15737 15737.08 HHS/Centers for To Be Determined 6412 3640.08 TBD

Disease Control & Cooperative

Prevention Agreement

Table 3.3.14:

Funding for Laboratory Infrastructure (HLAB): $0

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

PARTNER IS SOUTH TO SOUTH PARTNER TBD. Activity in 2008 was 12276.08 (Mech ID: 6128.08).

Below is a modified version of the COP08 Narrative:

This activity is related to lab capacity building activities implemented by APHL, ASM, MoH, and SCMS.

This activity has several different components of continuing and new activities with emphasis on in-service

training, capacity building at Central and Provincial Levels, and technical assistance to support quality

assurance and biosafety at Central Level. This support will utilize partnership through South to South (S to

S) collaboration, taking advantage of Portuguese language proficiency and experience developing

laboratory capacity in resource-limited settings. The goal of this activity is to provide laboratory expertise to

the Mozambican Ministry of Health to improve national laboratory service capacities. Activities will be

implemented through a Cooperative Agreement to a "To Be Determined" South to South Collaboration

Partner This TBD partner will support the Ministry of Health to implement its Strategic Plan for Laboratory in

collaboration with other PEPFAR partners working in the area of laboratory strengthening. FY2009 funding

will support the following activities:

1 - Continuation of technical training for Mozambican Lab Technicians in Brazil.

This training will provide a four month technical/practical training in immunology, biochemistry, hematology,

microbiology, as well as laboratory and quality management training for 15 (superior and medium level)

Mozambican Lab technicians. Training will be conducted in laboratories using modern instrumentation and

information management systems to provide trainees with optimal conditions to learn good laboratory

practice, work flow, quality assurance, information management, and professionalism. Training will be

supervised by specialized professionals and will include participation in daily/weekly laboratory sessions of

lecturing, case studies (including preparation of case studies by Mozambican trainee for presentation to the

group), and laboratory results review and interpretation. Post-training, Mozambican lab technicians will be

assigned to work in renovated and/or specialized laboratories within the Laboratory Network and will play

increasingly greater roles in the development and facilitation of in-country trainings in their area of expertise.

As technical capacity is built within this cadre of superior and medium level staff, and physical infrastructure

improvements at Provincial Hospital laboratories and Health Science Institute training labs is improved,

more of the technical training that is currently taking place outside of Mozambique can be shifted back to

Mozambique.

2 - Continuation of technical assistance (TA) to the National Immunology Reference Laboratory (INS) to

maintain and expand the national HIV rapid test serology External Quality Assurance (EQA) Program. Four

rounds of proficiency test (PT) panels (liquid) for HIV serology have been completed. Starting in round

three, samples positive for hepatitis B antigen (HBsAg) were included. Blood banks and clinical laboratories

routinely perform HBsAg testing and the addition of this parameter is essential to monitor quality of

screening and diagnostic procedures for Hepatitis B antigen. Starting with the next round of PT, dried tube

spots will be included along with liquid samples and an assessment of results using this alternative sample

type will be performed. In FY2009, TA will focus on scale up and decentralization of HIV serology EQA to

Provincial Level, including transfer of capacity and responsibility for HIV rapid test serology sight

supervision and training to Provincial Level laboratory staff. This will support the MoH's desire to increase

the routine training of staff performing HIV rapid tests as well as the efficiency and frequency of intervention

and re-training for testing sites that fail a given PT panel. TBD partner will collaborate with APHL, who will

receive FY09 funds to continue support to the logistics system to distribute panels and collect reports from

the provinces. Finally, TA will focus on simplified HIV sub typing methodologies to be transferred to INS

lab. This is to address the discrepancy whereby distribution of HIV-1 sub-type in Mozambique is very

heterogeneous and yet, most HIV rapid test technology is based on sub-type B. An important goal of TA

will be to address whether PT panel samples of different sub-types will perform equally well across the

country. As the INS lab maintains responsibility and expertise for characterization of samples which are

selected for PT panels, building capacity for sub-typing in the INS lab is crucial.

3 - Continuation of the In Country Project Manager (ICPM)

Two portuguese-speaking laboratory professional will be stationed in Mozambique as In Country Program

Managers (ICPMs). Their responsibilities will include: liaising between MoH, the US Government (USG),

USG Treatment Partners, and Project Directors in Brazil to ensure activities are implemented and results

are being achieved; preparing and facilitating Mozambican lab technicians for technical training in Brazil and

organizing training and mentoring by Brazilian experts in Mozambique; supervision visits to laboratories to

monitor performance of staff that have participated in the technical training in Brazil and/or been trained and

mentored through the laboratory mentorship program; participation in laboratory training activities with other

PEPFAR lab partners through curriculum development, course facilitation, and lecturing; and support to

MoH lab section in planning and implementation of National Strategic Plan.

4 - Continuation of Laboratory Mentorship in MoH laboratories performing CD4 lymphocyte count by flow

cytometry, biochemical and hematological tests. Three trainings for a period of 6-9 months will be

conducted with FY09 funding with 45 people trained. The goal of this program is build capacity through on-

the-job training in technical skills, biosafety, quality assurance processes, communication skills,

organization of work flow, lab inventory management, lab information management, daily equipment

maintenance and troubleshooting, time management and professionalism. Mentors will give weekly

seminars on relevant laboratory topics and encourage lab staff to participate in discussion and debate.

5 - Conduct a workshop to promote collaboration between clinicians and laboratorians. Results of previous

mentorships revealed that provision of quality laboratory testing services was impeded by the lack of

communication and collaboration between clinicians requesting lab tests and laboratorians performing tests.

Workshop organization will be lead by Mozambican physician being trained in clinical pathology who has: a

passion and understanding for the need to improve communication, respect among Mozambican

physicians, and the necessary experience to lead this effort. A small working group including clinical lab

Activity Narrative: directors, hospital medicine directors, and medical school faculty will be formed to develop scientific

program and follow up on impact, post-workshop. Participants in workshop will include laboratories,

physicians, medical school students and faculty, and laboratory training faculty from Health Science

Institutes.

6- FY2009 funds to TBD partner will support a technical advisor position within the MoH Laboratory section,

to build capacity of the department in strategic program planning and implementation. The Laboratory

Section staff are promising, but relatively inexperienced with little laboratory training and no laboratory

management or quality assurance management training. The proposed advisor will be a senior level

person with several years experience managing a laboratory network and will work with Laboratory Section

Head and his/her staff to define roles and responsibilities, processes, tools, and communication channels to

effectively manage the quality of the national laboratory network, in line with the National Laboratory

Strategic Plan.

Other activites to be implemented by this partner in other program areas include: $56,250 to laboratory

mentor for new Early Infant Diagnosis laboratory in Beira; $200,000 to support Counseling and Testing

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.16:

Funding for Strategic Information (HVSI): $0

THIS IS A NEW ACTIVITY

Many care and treatment sites in Mozambique have been scaled up with the support of one of 6

USG/PEPFAR-supported care and treatment partners as well as two non-USG funded external partners.

While many sites are using the standardized MOH-developed tools for data collection and reporting, in

some cases, these tools have substituted and/or additional paper based tools have been introduced by

partners. In some sites, only paper-based systems are used, while in other cases, partners have introduced

electronic systems for data management and reporting.

To better support MOH in improving quality of care, integrating HIV care and treatment services, and

ensuring sustainability of systems, USG PEPFAR is conducting an assessment with COP 08 funds to

generate recommendations so that PEPFAR-supported sites are better aligned with MOH systems and

standards, including the use of standardized MOH tools, flow of data from PEPFAR-supported sites through

national reporting systems, and more cost/resource-effective use of electronic patient monitoring systems.

Furthermore, activities currently under discussion by MOH to review and update the national M&E system

provide an opportunity to develop national guidelines or standardized operating procedures related to M&E

for care and treatment services, as well as a set of national standards for electronic data systems for HIV

care and treatment.

This activity will help to generate recommendations on:

1) New or modified data elements to be included as part of the minimum data set for patient monitoring in

Mozambique;

2) Best practices or recommended standards for paper-based and electronic data systems in Mozambique.

COP 09 funds are requested to support implementation of recommended priorities generated from the

assessment. Recommendations from the assessment with be reviewed and prioritized in consultation with

USG, implementing partners, and the Ministry of Health. These might include development of national

standards for electronic HIV information (e.g. HL7 standards for ART minimal data set), development and

dissemination of national protocols on data quality protocols, and/or technical assistance in modifying

existing partner systems to be more in line with the national standards and guidelines. It is expected that

preliminary recommendations will be generated by mid-FY09, at which point the partner and specific scope

of work will be determined.

New/Continuing Activity: New Activity

Continuing Activity:

Table 3.3.17:

Funding for Strategic Information (HVSI): $0

THIS IS A NEW ACTIVITY

BACKGROUND AND SUMMARY

Measurement of mortality is an important aspect of HIV surveillance. The Government of Mozambique is

working to improve mortality surveillance systems through strengthening of the hospital based reporting

systems, by improving collaboration between ministry of justice, national statistics institute, and ministry of

health, by revising the official death certificate, by implementing health and demographic surveillance sites,

by increased participation in WHO mortality reporting activities, and conducting special surveys. The

current process by which death registration moves from community, to health facility, to civil registry, to vital

statistics is not well understood. Further, these processes vary from province to province, with Maputo

demonstrating death registration rates ten times higher than Nampula in 2001, and with no estimates

available of registration rates in rural areas. This activity will cover expenses related to coordination

between these various activities.

ACTIVITIES and EXPECTED RESULTS:

Funds may be used to assess how death certificates currently flow through the health system and civil

registry system. Funds may be used for diverse activities related to death registration, including to increase

collaboration between ministries by sponsoring meetings and workshops on death and birth registration,

and to sponsor participation by local counterparts in regional and international meetings related to vital

statistics.

Through this activity it is expected that there will be both increased awareness of the limitations of traditional

vital registration among ministry technical staff, and improvements in registration rates leading to better

estimation of cause and age-specific mortality.

New/Continuing Activity: New Activity

Continuing Activity:

Table 3.3.17:

Funding for Strategic Information (HVSI): $0

Continuing Activity: (No new funds in FY09)

SUMMARY AND BACKGROUND:

This activity is associated with Mozambique's SI five year strategy to technically and financially support

surveillance to monitor HIV/AIDS-related illnesses, understand the behaviors that influence transmission,

improve access to and use of care and treatment services, strengthen the effectiveness of program

activities, and ensure a supportive environment for USG efforts.

MOH, in coordination with donor and technical assistant partners, began implementing routine HIV sentinel

surveillance among pregnant women in 1998 in 10 sites. Since 2001, CDC has provided complete financial

and technical support for sentinel surveillance activities in Mozambique. In 2007 during the latest round,

sentinel surveillance was conducted at 36 sites throughout the country and dry blood spot (DBS)

technology, BED incidence assays, and threshold ARV resistance monitoring were introduced.

ACTIVITIES and EXPECTED RESULTS:

Funds will be used to train survey personnel including maternal and child health nurses, laboratorians,

district and provincial supervisors, as well as prepare data collection instruments, move supplies to and

from surveillance sites, and conduct site assessments and supervision for the 2009 sentinel surveillance

round. This activity is related to activities 15916.08 and 8639.08.

New/Continuing Activity: Continuing Activity

Continuing Activity: 19911

Continued Associated Activity Information

Activity Activity ID USG Agency Prime Partner Mechanism Mechanism ID Mechanism Planned Funds

System ID System ID

19911 19911.08 HHS/Centers for To Be Determined 6412 3640.08 TBD

Disease Control & Cooperative

Prevention Agreement

Table 3.3.17:

Funding for Strategic Information (HVSI): $0

THIS IS A NEW ACTIVITY

SUMMARY AND BACKGROUND:

Mozambique will conduct its first population-based AIDS Indicator Survey (AIS) in early 2009. Further, this

is the Ministry of Health's first attempt to conduct a national seroprevalence survey. Conducting this survey

in Mozambique is presenting many challenges that lead to uncertainty regarding budgeted activities. These

uncertainties are due in part to fluctuating fuel prices, delays which have led to implementation during the

rainy season, lack of infrastructure, concerns about social mobilization, and the need to produce materials

in English and Portuguese.

While the survey fieldwork is funded via the NAC, and technical assistance and laboratory support,

including procurement, is funded in COP08, this activity will provide additional funding to cover unexpected

expenses associated with the survey.

ACTIVITIES and EXPECTED RESULTS:

Activities to be conducted with these funds include translations, development of informational materials,

purchase of test kits and reagents, travel expenses related to supervision, dissemination activities and a

national prevalence estimation workshop to combine results from ANC sentinel surveillance and the AIS.

Through this activity it is expected that the AIS survey will be successfully completed leading to improved

national and provincial HIV prevalence estimates and updated behavioral data that is critical to assessing

prevention activities in Mozambique.

This activity is related to activity 10211.08.

New/Continuing Activity: New Activity

Continuing Activity:

Table 3.3.17:

Funding for Strategic Information (HVSI): $0

THIS IS A NEW ACTIVITY

In previous years, all administrative and logistical support for in country surveys, including surveillance

systems, have been done through the General Services Office (GSO). The volume of these purchase

orders (PO) has increased drastically in the last year and these POs have become increasingly complex

and complicated to award through the GSO. We anticipate the work load to further increase in FY09 as

described below.

The Ministry of Health, with technical assistance from the Centers for Disease Control and Prevention

(CDC), is currently working on the implementation of several surveys, and surveillance activities.

Currently, the MOH with assistance from its partners have 17 surveys in progress , and the PEPFAR team

has applied for 8 multi country public health evaluations (PHEs), and 3 Mozambique specific PHEs.

The Mozambique program needs a flexible and quick mechanism that will enable the USG to help the

Ministry of Health implement the above mention surveys and PHEs in a timely fashion. To help with the

logistical and administrative support for Mozambique's multiple surveys, surveillance activities (including

BSS) and potential PHEs, the CDC is developing a new competitive indefinite delivery, indefinite quantity

(IDIQ) contract. An IDIQ contract works through task orders that can be awarded with a short turn around

allowing for services to be delivered in a timely manner.

The contractor is expected to coordinate and implement all logistical and administrative aspects of the

surveys (including, surveillance systems, BSS, PHEs and additional assessments needed such as a

national alcohol assessment). Some of the funds will be used for start up expenses of a local contractor;

the rest of the funds will be used for first year programmatic expenses which include:

- data collection services for surveys, including PHEs

- data cleaning, management, analysis, and entry

- rapid turn around translations

- logistical support for multiple surveys in multiple sites (i.e. coordination of staff and questionnaires,

coordination and overseeing of data transport, data entry, cleaning, etc)

- potential transport of survey and admin coordinators

- survey instrument development and validation

- statistical support

- other logistical and administrative services as needed

Expected deliverables: identification of local contractor to provide services covered in the activities above.

contractor may also need to subcontract with other smaller local service providers to address needs in

different provinces.

New/Continuing Activity: New Activity

Continuing Activity:

Table 3.3.17:

Funding for Health Systems Strengthening (OHSS): $0

This is a new activity but received initial start-up money in COP 08 as activity 19910.08.

As noted in other sections in this COP, a key focus for COP 09 is increasing SI capacity, specifically

building a cadre of Mozambicans with appropriate and adequate skills to carry out necessary strategic

information activities in Mozambique. The USG team is using a variety of shorter- and longer-term

strategies and activities to support this capacity. While some other SI capacity building activities (e.g.

strengthening M&E curriculum at Masters of Public Health Program at the University of Eduardo Mondlane

and Field Epidemiology Training Program) will be expected to increase the number of and skills of

Mozambicans in Strategic Information, the M&E Fellowships Program recently initiated as part of South

Africa's PEPFAR Program provides an opportunity to increase M&E and other SI related skills among

Mozambicans in the shorter term (1-2 year timeframe.)

The University of Eduardo Mondlane School of Medicine has the only MPH program in Mozambique. It

began in 2001 and typically has enrollment of 30 students from Mozambique and other African countries.

The program received support from NORAD to develop an informatics track but that support has ceased.

Emory University also provides support in the form of student scholarships around the area of injury

prevention.

There is a need for a cadre of health care workers trained in public health and UEM is currently the sole

source of a degree in this field. In years previous, CDC was approached by UEM to provide support to this

program but there was instability within the organizational capacity of the program making it difficult for them

to develop an list of areas where they needed support. The faculties were all part time and therefore no one

of them was able to focus more than part of their time on the program. In FY08, CDC met with the

University of Eduardo Mondlane -MPH program to discuss the status of the program, their needs and how

we might work with them. Given favorable progress on the limited scope of FY08 activities, in FY09, we will

seek to provide support directly.

In FY09, funds will be used to develop a sole source RFA for continuing support to the MPH program. The

use of these funds will be defined according to the scope of the RFA and needs of the program.

Deliverables:

RFA developed and awarded

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Estimated amount of funding that is planned for Education

Water

Table 3.3.18:

Funding for Health Systems Strengthening (OHSS): $0

This is a new activity.

This activity will contribute to capacity building of the MoH staff, with the goal of producing highly qualified

medical personnel to provide health care services and assume leadership roles within the health system

particularly with respect to Tuberculosis, HIV, malaria and other infectious diseases.

The Ministry of Health provides in service training in HIV/AIDS and management for medical doctors

immediately after the general medical training. This is a 3 week intensive course that covers several

aspects of HIV such as virology, nutrition, PMTCT, M&E and prevention. Upon completion, the medical

doctor is certified to provide ARV therapy in the health facilities. There is no infectious diseases

specialization program in place at any of the medical schools in Mozambique. The Ministry of Health has

been exploring possibilities of sending students abroad to receive this training.

The proposed activity is to support the development of an infectious diseases fellowship program that would

be offered at post-graduate level to medical doctors. This activity will help build clinical capacity in

Mozambique with respect to management and leadership in the three main endemic diseases (HIV, malaria

and TB), as well as other infectious diseases of public health significance in the country.

The USG will collaborate with the Ministry of Health, Medical Council of Mozambique (Ordens dos

Medicos), Universities and other partners to develop and implement a training program defining the

curriculum content, target group and duration of the program.

During FY09, the following will be achieved with the funding proposed: an assessment to define curriculum,

and complete the training curriculum and materials for a post graduate Infectious disease fellowship

program for Mozambique. Funding in subsequent years will be used for implementation of actual training

courses, course evaluations and expansion as appropriate.

Products/Deliverables

Assessment concluded

Fellowship plan developed

Curricula content defined

Training material developed

Partnerships with relevant Mozambican and other (Brazilian, Portuguese, USA) training institutions

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Estimated amount of funding that is planned for Education

Water

Table 3.3.18:

Funding for Health Systems Strengthening (OHSS): $0

This is a new activity.

As noted in other sections in this COP, a key focus for COP 09 is increasing SI capacity, specifically

building a cadre of Mozambicans with appropriate and adequate skills to carry out necessary strategic

information activities in Mozambique. The USG team is using a variety of shorter- and longer-term

strategies and activities to support this capacity. While some other SI capacity building activities (e.g.

strengthening M&E curriculum at Masters of Public Health Program at the University of Eduardo Mondelane

and Field Epidemiology Training Program) will be expected to increase the number of and skills of

Mozambicans in Strategic Information, the M&E Fellowships Program recently initiated as part of South

Africa's PEPFAR Program provides an opportunity to increase M&E and other SI related skills among

Mozambicans in the shorter term (1-2 year timeframe). Furthermore, Mozambique's participation in the

South Africa Fellowship program provides an opportunity for Mozambique to determine if and how a

Mozambique-specific Fellowship can be developed within Mozambique in the coming years.

In this six-month fellowship program, graduates of Masters in Public Health programs are matched with

PEPFAR partners that are in particular need of M&E support. This program is aimed to create opportunities

for Masters of Public Health students to gain practical experience in monitoring and evaluation within a

mentorship work environment. This is a strategy to provide career development opportunities that help to

improve retention of local (Mozambican) staff with these "scarce skills" sets.

These Mozambican M&E Fellows will be placed with South African PEPFAR Partners during their Masters

degree study period in order to gain practical experience. These practical skills may then be ploughed back

into Mozambique when Fellows return home after study completion.

This activity is currently listed out as TBD until the appropriate mechanisms can be worked out with the

PEPFAR South Africa office, and the Foundation for Professional Development (FPD) who is administrating

the Program on behalf of PEPFAR South Africa.

In accordance with the policy used in the South Africa Fellowship Program, each Fellow will have to enter

into a contract that will oblige them to a specific period of skills transfer and capacity building within

Mozambique. The criteria developed for an individual receiving a scholarship for long term education will be

referred to in developing this contract.. This could be done by means of an intra-african parallel transfer by

a PEPFAR Partner within South Africa to their relevant branch in other African countries as part of the

Africans Building Human Capacity in Africa "scarce skills" retention initiative.

Funds requested will cover the logistical costs related to such fellowship placements for African students.

With $100,000 in COP 09 funds, we anticipate that approximately 5 Mozambican fellows can participate in

this critical capacity building project.

Deliverables:

Establish mechanism for M&E fellowships

Select and send 5 Mozambicans to begin their fellowship

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Estimated amount of funding that is planned for Education

Water

Table 3.3.18:

Funding for Health Systems Strengthening (OHSS): $0

This is a new activity.

In 2007, the sentinel surveillance results in Mozambique estimated that the HIV prevalence among women

and men aged 15-49 to be 16% overall with actual provincial figures ranging from 20%-9%. Surveillance

results also showed that the epidemic is still on the rise in most provinces. According to other national and

regional analyses show that the key driver for Mozambique is the pervasive practice of multiple and

concurrent partners. Other drivers of the epidemic include early sexual debut, low condom use, low rates of

male circumcision, high level of women engaged in intergenerational sexual relations, low level of HIV

knowledge and gender-based violence.

In Mozambique, there are a number of pre-service training institutions where teachers and health care

workers receive their initial training. These institutions are located in urban and rural settings and tend to

serve more than one province. In order to gain education, young people may travel a significant distance

from their homes for up to 30 months in order to attend a pre-service education institution. The quality of

infrastructure and resources available at each training institution varies with some possessing renovated

accomodations, classrooms and humanistic lab while others are still in need of much repair. Recreational

facilities are scarce among the training institutions so students must either make due with what is at the

training institution or travel to a nearby town for recreational opportunities.

Although students are being prepared to educate others either in the classroom or as clinicans, they are not

recepients of HIV prevention education while in pre-service education. While frequently there are provisions

to prevent students from catching malaria in the form of mosquito nets for their beds, there seems to be a

dearth of information and resources around HIV/AIDS, TB, and OIs. Given the social mores in Mozambique,

the percentage of HIV+ individuals in the general population and the huge need for health care workers and

teachers, it does not seem prudent to fail educating students as they attend pre-service, typically for 18-30

months. Also PEPFAR partners have anecdotally reported that they have seen first year nurses and

teachers die from AIDS related illnesses.

This RFA would look at how a TBD partner could work across ministries (Minstry of Health, Ministry of

Education and Ministry of Defense) to assess suitability of educational campaigns educating students on

abstience and being faithful; HIV/AIDS, TB, OIs; identify sites for testing and treatment and developing a

system for condom distribution. Information from the health worker KAP study, where knowlege, behavior

and attitudes was measured in existing health care workers along with assessment results from the Ministry

of Education and Military will be utilized as background information.

Products/deliverables

Assessment of suitablilty of educational campaigns/activities and feasibility of providing testing and

treatment services for students at pre-service institutions

Developing an implementation plan for moving this overall project from concept to implementation

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Estimated amount of funding that is planned for Education

Water

Table 3.3.18:

Funding for Health Systems Strengthening (OHSS): $0

Funds will be reprogrammed as programmatic need arises in the systems strengthening technical area.

Possible uses of funds include additional support for newly competed country managed co-ags, Field

Epidemiology and Laboratory Program, and support for emergent Ministry of Health priorities.

New/Continuing Activity: New Activity

Continuing Activity:

Table 3.3.18: