Detailed Mechanism Funding and Narrative

Years of mechanism: 2010 2011 2012 2013

Details for Mechanism ID: 9438
Country/Region: Cambodia
Year: 2013
Main Partner: National Center for Tuberculosis and Leprosy Control - Cambodia
Main Partner Program: NA
Organizational Type: Host Country Government Agency
Funding Agency: HHS/CDC
Total Funding: $200,000

Goals and Objectives.

This program strengthens the capacity of the National Center for Tuberculosis and Leprosy Control (CENAT) to diagnose tuberculosis (TB) rapidly and reliably in HIV infected patients and prevent spread of multi-drug resistant TB (MDR TB). Objectives are to: implement and evaluate the roll-out of TB diagnostics; support scale up of the Three-Is -- intensified TB/HIV co-infection case-finding, isoniazid prophylaxis, and infection control practices; and build capacity of health care staff nationally to diagnose and treat TB.

Target population and geographic coverage.

This program targets patients with HIV or those suspected to have MDR TB in Cambodia. Implementation and evaluation of diagnostics will be carried out in Phnom Penh and six other provinces.

Cost efficiency. The evaluation will assess feasibility and costs of introducing new laboratory methods in Cambodia. Scale up of activities will utilize Global Fund resources. Activities are coordinated among donors at technical working group meetings to avoid duplication.

Monitoring and Evaluation. Activities are monitored through monthly laboratory reports, quarterly activity reports and joint site visits. The TB technical working group meets bi-monthly to monitor progress. National targets and achievements are reviewed at the annual TB meeting, led by CENAT. National activity plans are developed in collaboration with all donors.

Transition to government partner. The partner is responsible for the national TB program. Operations research completed in 2009 led to policy changes. Initial PEPFAR capital investments in infrastructure and equipment are being scaled up through Global Fund. In-country, regional, and headquarter USG staff provide technical assistance and monitoring to CENAT.

Funding for Care: TB/HIV (HVTB): $200,000

The Ministry of Healths Center for Tuberculosis and Leprosy Control (CENAT) is responsible for tuberculosis (TB) activities in Cambodia. CENAT relies on funding from the Global Fund for program implementation and drug and commodities procurement. TB prevalence decreased between 2006 and 2011 (prevalence survey dissemination 2/2012), but remains among the highest in the region. Tuberculosis is the leading cause of mortality for people living with HIV. As a result of U.S. government support, CENAT initiated an aggressive plan in 2010 to identify patients with TB/HIV co-infection and provide isoniazid preventive therapy to eligible patients in collaboration with the National HIV Program. TB liquid culture and drug susceptibility testing was initiated in 2 laboratories in 2011 and CENAT assumed direct responsibility for implementing multiply drug resistant TB (MDR TB) case finding. Local and international partners working on tuberculosis activities in Cambodia have agreed to use standardized patient registries.

In 2012 the cooperative agreement will support: implementation and scale-up of TB liquid culture; finalization of the TB laboratory strategic plan 2011-2015; and evaluation of the impact of GeneXpert in terms of case finding, treatment outcomes, laboratory workload and cost. Training on the clinical and laboratory protocols for TB/HIV and MDR TB and will be provided to laboratory workers, DOTS providers and nurses and physicians working in 17 provinces. CENAT will finalize and implement laboratory and clinical algorithms for active case finding of MDR TB, and TB/HIV using GeneXpert. An assessment of infection control needs will be carried out in TB clinics and HIV treatment sites. Based on the results, patient and provider educational materials will be developed, and strategies to address infrastructure needs outlined.

Standardized reporting tools will be developed to track patients and link laboratory results to medical records. Joint site visits involving CDC and CENAT staff will be undertaken to monitor program progress and track indicators.

Cross Cutting Budget Categories and Known Amounts Total: $60,000
Human Resources for Health $60,000
Key Issues Identified in Mechanism
Tuberculosis