Detailed Mechanism Funding and Narrative

Details for Mechanism ID: 4999
Country/Region: Zambia
Year: 2007
Main Partner: Chest Diseases Laboratory
Main Partner Program: NA
Organizational Type: Host Country Government Agency
Funding Agency: HHS/CDC
Total Funding: $200,000

Funding for Laboratory Infrastructure (HLAB): $200,000

This activities is linked to all TB/HIV activities nationally and TDRC (#9027).

The Chest Diseases Laboratory (CDL), Zambia's national tuberculosis (TB) reference laboratory, has been supported by the Centers for Disease Control and Prevention (CDC) since 2000. This facility is responsible for quality control and quality assurance of TB microscopy and culture and drug susceptibility testing for all sites in Zambia.

In fiscal year (FY) 2006, this activity supported training for district laboratory staff in four provinces complementing similar training provided to districts in the remaining five provinces by Tropical Diseases Research Centre's (TDRC).

Through this activity a National Quality Assurance system is being implemented to improve the quality of diagnosis of TB in HIV-positive individuals. Frequent supervisory visits, blind-slide rechecking of AFB smears selected randomly, and testing a standard panel testing of smears are now taking place. By the end of FY 2006 fifteen laboratory staff will have been trained on bio-safety, techniques for reducing contamination, and twenty staff will have been trained in the use of the fluorescent microscope.

Other services currently provided include Internet support and transport for the reference laboratory to enhance transport of specimens, lab supplies, generator, iso-temp incubators, Revco fridges, ultra flow fridges, fluorescent microscope, and bio-safety cabinets.

In April 2006, the recently renovated administrative office for the CDC and CDL staff opened. This renovation has provided for more laboratory work space in addition to extra room to accommodate management and supervising staff. The renovation has allowed the CDC's technical laboratory experts to provide frequent on-site training and mentoring support to the national laboratory staff. In addition, having the CDC technical lab experts housed in the same compound allows for frequent supervision and monitoring of equipment.

CDL is also supported through the national TB program funded by the Global TB Fund and has a long working relationship with the Zambart Project supported by the Bill and Melinda Gates Foundation. Currently, the laboratory has two rapid TB culture systems provided through this project. The Zambart Project also provides technical support and human resource capacity to the national TB laboratory staff. As a result of this support CDL is well equipped to provide technical assistance to provincial and district laboratories. The USG and contributions of Zambart, and the Gates Foundation complement each other.

In FY 2007, the USG will continue to support the laboratory human resource capacity building for external quality assurance of smear microscopy. The CDC is also supporting the feasibility study for offering liquid culture and rapid first line drug susceptibility testing to support TB control and drug resistance monitoring. Other support will include the following activities; 1) improvement of human resource capacity by the placement of extra staff in the laboratory to properly perform national quality assurance activities and give timely feedback to laboratories within the laboratory network; 2) procurement of computers, training for laboratory staff, and continued support to maintain the local area network within the laboratory to ensure continued access to Internet facilities and the ability to communicate with the Ministry of Health and other Provincial and District centers within the country; 3) training of 260 laboratory staff participating in culture and external quality assurance program to support HIV care and treatment; and 4) and courier transport for specimens from chest clinics within four provinces to the reference laboratory for the drug resistance testing and surveillance monitoring.

USG is working closely with the Ministry of Health and provincial health offices to ensure the training and equipment being provided supports the national system and is sustainable.