Detailed Mechanism Funding and Narrative

Details for Mechanism ID: 4816
Country/Region: Uganda
Year: 2007
Main Partner: Uganda Virus Research Institute
Main Partner Program: NA
Organizational Type: Host Country Government Agency
Funding Agency: HHS/CDC
Total Funding: $675,000

Funding for Testing: HIV Testing and Counseling (HVCT): $350,000

plus ups: To scale up rapid HIV testing services and accompanying External Quality Assurance. Central Public Health Laboratory (CPHL) will expand the training on rapid HIV testing including finger stick techniques to enable non laboratory personnel to provide testing services outside health facilities. EQA will ensure that accurate performance of HIV testing is maintained in all HCT sites and communities

Table 3.3.09:

Funding for Laboratory Infrastructure (HLAB): $325,000

The Ministry of Health (MOH) with support from the international community has continued to scale-up the provision of ART to those who are HIV-infected and eligible for therapy. Recently, MOH in collaboration with the Uganda AIDS Commission (UAC) has launched new preventive strategies to drive the HIV seroprevalence below the current 6.4%. There is now an urgent need to have high-quality HIV serological testing in all the laboratories across the country. The importance MOH places on providing comprehensive, high-quality laboratory services throughout the country is reflected in the newly-established position of Assistant Commissioner to oversee the activities of the Central Public Health Laboratories (CPHL) and in particular, the implementation of a quality assurance program according to the HIV Rapid Test Quality Assurance Manual, Uganda, 2006. Building on the experience built over the past 3 years with USG funding, the HIV Reference and Quality Assurance Laboratory at the Uganda Virus Research Institute has established a national laboratory quality assurance (QA) program focused specifically on HIV-related testing. We were recently awarded another CDC Cooperative Agreement for the period of 09/30/2006 - 09/29/2011 to continue the development and strengthening of this program to assure the quality of HIV testing nationwide. Working with existing programs within MOH, particularly the Quality Assurance Unit, the HIV rapid test training coordination unit at CPHL and regional and district-level laboratory supervisors, we shall identify laboratories currently conducting HIV serological testing and the tests/algorithms used, to include the national blood bank, national HIV surveys, HCT and PMTCT programs, as well as clinical laboratories, in both the private and public sector. Based on the inventory of HIV-testing laboratories, we shall develop a quality assurance plan that takes advantage of supervisory visits conducted by CPHL and the National TB and Leprosy Program to distribute proficiency testing (PT) panels, to collect quality control (QC) samples for testing at UVRI and to meet reporting requirements. Laboratories failing to meet QA criteria will be visited and remedial action taken. Testing algorithms for use in the field and for QC at UVRI will be continuously monitored and new algorithms evaluated.

Support will be required at UVRI to service this expanded QA activity including procurement of equipment to ensure safe-practice and for a specimen repository, test kits for QC testing and commodities for the preparation of PT panels with special emphasis on the latter since QC testing will likely prove a non-sustainable QA activity as the number of sites conducting HIV testing increases. The existing LIMS will be expanded and linked to databases at CPHL and MOH to facilitate reporting, logistics management and training needs. Support will also be required for UVRI staff to conduct laboratory testing, to participate in up-country supervisory visits and in the training/re-training of health-facility staff as part of the national laboratory training team.

UVRI will develop a realistic work-plan with achievable progress indicators and a detailed budget to cover the first year of funding. Special attention will be given to the development of both a laboratory management plan and a plan for monitoring and evaluation All activities will be in line with the Uganda National Quality System Guidelines.

plus ups: QA activities for HIV serology are an essential component of national HIV/AIDS programs. This activity is currently the responsibility of UVRI and is coordinated by CPHL Activities include the preparation and distribution of proficiency panels, quality control testing of specimens from the field, and evaluation of new HIV testing kits and algorithms. Through coordination with other national programs including those for TB and malaria, UVRI staff supported by PEPFAR also contribute to national support supervision; funding of US$ 75,000 is requested to expand and strengthen HIV QA and support supervision activities.