Detailed Mechanism Funding and Narrative

Details for Mechanism ID: 10484
Country/Region: Rwanda
Year: 2009
Main Partner: Columbia University
Main Partner Program: NA
Organizational Type: University
Funding Agency: HHS/CDC
Total Funding: $1,230,000

Funding for Treatment: Adult Treatment (HTXS): $0

This PHE activity, Evaluating adherence to antiretroviral therapy among HIV care and treatment patients in

Rwanda: A retrospective cohort study, was approved for inclusion in the COP. The PHE tracking ID

associated with this activity is RW.07.0198.

Note: This PHE is funded by carry over funds from 2007. There does not appear to be a narrative in 2008,

therefore we could not mark this activity as continuing. -NComella

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Human Capacity Development

Public Health Evaluation

Estimated amount of funding that is planned for Public Health Evaluation $0

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.09:

Funding for Care: Pediatric Care and Support (PDCS): $125,000

ACTIVITY UNCHANGED FROM FY 2008:

The USG, in collaboration with the GOR and Columbia University, has provided funding for the

development of two pediatric HIV care and treatment Centers of Excellence (COE) located at the Kigali

Hospital Center (Centre Hospitalier de Kigali or CHK) and the Butare University Hospital Center (Centre

Hospitalier Universitaire de Butare or CHUB). CHK and CHUB are the two largest referral centers in the

country; the only medical school in the country is located at CHUB. Renovations at the CHK pediatric HIV

center of excellence were completed earlier in 2008 and it is now fully operational; 5 physicians, 5 trained

pediatric HIV nurses, one data manager and one administrator staff this out-patient clinic that provides

services to 163 HIV-infected children of which 119 are currently receiving ART. Approximately, 192 HIV-

exposed infants are also followed at this site. Approximately, 293 children are in care at CHUB (161 on

ART). Personnel from both CHK and CHUB COEs provide PITC services for children at various pediatric

entry points and work to link these children and their families to care and treatment services at the COEs, or

at ART facilities closer to their homes. In FY08, both COEs will be fully operational and will be instrumental

in providing clinical services for complicated pediatric HIV cases referred from District Hospitals, in providing

long-distance patient management advice and on-sites staff mentoring, and so will constitute a major

training resource for the national pediatric HIV program.

In FY 2009, the COE will be supported to greatly expand its role in supporting the national pediatric HIV

program in Rwanda in coordination with the MOH, the CIDC, and other implementing partners. The COEs

in Kigali and Butare will be used to support training of physicians in pediatric HIV management. The cadre

of pediatric nurses will be used to train staff from clinical sites on issues related to testing children in various

clinical settings as well as on counseling children's parents' and on HIV diagnosis disclosure for older

children. A group of physicians from the COEs will provide long-distance mentoring support,, discuss

management of difficult cases with district hospitals staff, and and serve as on-site training resources for

health care providers from the various districts hospitals and health centers, in order to improve their

pediatric HIV clinical skills. ICAP will also work with CIDC and CHUK to train and supervise a cadre of

highly trained CIDC mentors who will be critical in harmonizing the approach of pediatric HIV care best

practices for all the sites, and continuously improve overall pediatric care quality throughout the country.

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Health-related Wraparound Programs

* Child Survival Activities

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $125,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.10:

Funding for Treatment: Pediatric Treatment (PDTX): $325,000

This is a continuing activity from FY 2008. No narrative required.

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Health-related Wraparound Programs

* Child Survival Activities

* TB

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $175,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.11:

Funding for Care: TB/HIV (HVTB): $780,000

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS:

The overall goal of this activity is to build capacity at central level for to support TB/HIV integration at all

levels. TB/HIV capacity building includes development, revision or updating of TB/HIV guidelines for adults

and children, creating training materials and job-aids, sharing best practices, improving TB diagnosis, and

enhancing supervision and monitoring evaluation of TB/HIV integration activities.

In FY 2009, Columbia University will continue to support TB/HIV collaborative activities at central level

through continuation of support for a long-term advisor and four national supervisors seconded to the

national TB program to oversee collaborative activities. These include providing support to the national

TB/HIV working group for revising and updating guidelines, curriculums, and tools. It also includes providing

support for supervision of quality TB and HIV service delivery to co-infected patients - particularly to

strengthen the implementation of routine HIV counseling and testing, prevention education, and referral for

HIV care (if needed) for all patients with TB at the TB/DOT clinics. Additionally, it includes implementation of

standardized symptom-based TB screening and intensified TB case-finding for patients living with HIV at

the ART clinics. In addition, Columbia is supporting the PNILT with the implementation of an electronic TB

register at selected sites. Support for two model centers established in FY 2005 will continue, Columbia

(through its agreement with PNILT and NRL) is strengthening TB capacity throughout the Rwandan

laboratory network. Lower-tier laboratories will use basic Ziel-Nielsen staining of specimens, and three

reference laboratories located in NRL, Kigali University Teaching Hospital (KUTH), and Butare University

Teaching Hospital will perform more complex assays such as TB culture, TB molecular diagnostics (PCR),

TB drug susceptibility testing, diagnostics for Mycobacterium Avium Complex (MAC) and other atypical

mycobacterium. In addition, the three reference laboratories will oversee the training and supervision of TB-

related activities in the lower tier labs to improve the quality of microscopy-based diagnostic tests. A strong

referral system will be developed to transport specimens from the lower tier labs to the reference

laboratories for TB culture and other specialized tests.

Quality assurance systems were strengthened by providing TA to the NRL for the development of an

external quality assurance (EQA) program for TB-related diagnostics. The CHK pathology lab will be up-

graded to accommodate the increasing volume of TB-related anatomical pathology and clinical pathology

specimens. Finally, these funds supported the drafting of a national strategic plan for TB lab diagnostics and

lab network strengthening in coordination with the overall national plan for integrated TB and HIV activities.

In addition to the TB laboratory activities, ICAP will strengthen TB/HIV integration in three prisons currently

providing ART services in Rwanda (ICAP-supported sites). Priority will be placed on assuring that systems

are in place for effective data collection and tracing as prisoners with HIV and prisoners with TB and HIV

are released into the community. ICAP will hire staff to work with the prisons on these aspects of TB/HIV

integration and assist with the coordination of these activities with KUTH, BUTH, NRL and PNILT. ICAP will

procure all equipment and contract with a local company to renovate laboratories in the Butare University

Hospital.

In addition, Columbia University will support additional staff positions and training at NRL, for TB culture

molecular diagnostics (PCR), TB resistance testing, MAC and other atypical mycobacterium diagnostics as

the demand is expected to grow in FY 2009 with scale-up active TB case findings among PLWA , smear

negative suspect TB clients and their families. Columbia will continue to support the network of TB labs with

transportation of specimens from low tier lab to the main three labs NRL, CHK and Butare University lab. In

FY 2009 Columbia will support the decentralization of TB quality assurance to decrease the workload on

NRL. These activities will reinforce timely diagnosis of extra pulmonary and smear negative TB thus

decreasing the high mortality currently associated with delayed diagnosis of these types of TB disease.

Columbia University was awarded the UTAP follow-on in August 2008, thus there will be continuity in the

activities outlined above.

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $150,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.12:

Funding for Laboratory Infrastructure (HLAB): $0

ACTIVITY HAS BEEN MODIFIED IN THE FOLLOWING WAYS

1. Elaboration of activities

In FY 2009, Columbia will continue its TA and capacity building activities at NRL by supporting technical

activities as well as strengthening the institutional infrastructure and management capacity critical to sustain

the national network of laboratories for the Rwandan HIV care and treatment program. Direct TA will

continue to be provided through long-term advisors and periodic short-term consultants as needed. Two

long-term technical advisor positions will be continued in FY 2009. The first provides support for HIV-

related quality laboratory services, including evaluations of new technologies, technician trainings and

guidance on technical and policy issues. The second advisor, a local hire senior lab technician will remain

responsible for development and implementation of national standards, QA systems and training. These

two technical advisors will continue to transfer skills, knowledge and capacity, ensuring a sustained impact.

Columbia will continue to support laboratory TA to the NRL and CHUB TB laboratories to ensure reliable

AFB and high quality smear microscopy, liquid culture and drug sensitivity testing capability at the health

facility level. These TB diagnostic and treatment capabilities are essential in order to provide PLWHA

adequate access to comprehensive quality TB-related services. These capabilities are also essential for

the support of patients with MDR TB. Extrapulmonary TB diagnostics will be available through continued

support to CHUB and CHUK anatomical pathology laboratories.

Atelier Central de Maintenance (ACM) and NRL maintenance units for laboratory equipment will be

strengthened through training and staffing to guarantee the quality of results within the national laboratory

network. Also, small laboratory renovations will be performed to assure building sustainability inside the

national laboratory network.

Columbia will also continue to strengthen and integrate QA/QC/QI at the NRL into all HIV-related laboratory

areas serology, biochemistry, hematology, CD4, TB and malaria. New QA/QC approaches will continue to

be explored in those HIV specific areas. National specimen transportation systems will continue to be

strengthened. Specific laboratory target evaluations on new technical alternatives and new technologies

will be supported to improve the accessibility and reliability of care and treatment programs. For example,

new alternative technologies will focus on specific HIV areas like, CD4 or TB infant diagnostics. Protocols

and/or indicators should be designed to evaluate laboratory performance impacts on care and treatment

programs.

In collaboration, CDC, APHL and Columbia will support NRL to develop a highly functional national

laboratory information system for NRL, and will work, utilizing existing funds, to extend this system to district

hospitals. The laboratory information system will manage financial record keeping, as well as specimen

tracking, inventory control and programmatic indicators.

All of these activities are consistent with Rwanda's five-year strategic goals of strengthening NRL's capacity

to manage a national network of laboratories, standardize technical approaches and support QA of HIV-

related services throughout the national laboratory network.

New/Continuing Activity: New Activity

Continuing Activity:

Emphasis Areas

Human Capacity Development

Estimated amount of funding that is planned for Human Capacity Development $100,000

Public Health Evaluation

Food and Nutrition: Policy, Tools, and Service Delivery

Food and Nutrition: Commodities

Economic Strengthening

Education

Water

Table 3.3.16:

Cross Cutting Budget Categories and Known Amounts Total: $550,000
Public Health Evaluation $0
Human Resources for Health $125,000
Human Resources for Health $175,000
Human Resources for Health $150,000
Human Resources for Health $100,000