Detailed Mechanism Funding and Narrative

Years of mechanism: 2007 2008 2009

Details for Mechanism ID: 5739
Country/Region: Uganda
Year: 2008
Main Partner: Baylor College of Medicine
Main Partner Program: Children's Foundation-Uganda
Organizational Type: University
Funding Agency: HHS/CDC
Total Funding: $7,272,603

Funding for Sexual Prevention: Abstinence/Be Faithful (HVAB): $200,000

The program will support the expansion of comprehensive HIV/AIDS prevention, care and treatment

services to HIV-infected children and their families and provide pediatric HIV training opportunities for

clinical and ancillary health professionals.

Comprehensive HIV services will include antiretroviral therapy (ART); adherence counseling; tuberculosis

(TB) diagnosis and treatment; diagnosis and treatment of opportunistic infections (OI); provision of basic

preventive care package (BCP); confidential HIV counseling and testing; family support interventions

including prevention with positives and discordant couple counseling for parents; family psycho-social

support; and related interventions for orphans and vulnerable children (OVC). Following national pediatric

treatment guidelines and strategies, in FY08 program initiatives will continue the care and treatment of

pediatric and family member patients and expand quality pediatric care to additional clients using a family

centered approach to ensure the pediatric patients and their families receive related services and support

required for OVCs.

In support of national services and satellite sites and to ensure full access to high-quality pediatric care and

treatment services throughout the country, initiatives to train and mentor doctors, nurses, counselors, and

allied health care providers in the public and private sector will be established to support basic preventive

palliative care, and antiretroviral provision to children living with HIV/AIDS. The program will participate in

the development of the Uganda national Positive prevention curriculum and provide leadership in area of

adolescent care, e.g. disclosure, sex and sexuality, adolescent counseling.

Activities to integrate prevention messages into all care and treatment services will be developed for

implementation by all staff. Specific interventions to support adolescent care, treatment, adherence, and

prevention message will be developed and integrated into clinical and family services. Regular abstinence

being faithful (AB) messages will be provided for Adolescent and Youth peer support groups. Health

education sessions including "Positive Prevention" (PP) messages will be provided both in-clinic and

through home counseling. These messages will target children over 12 years of age and their family

members especially parents. For older children 13 years and above and youth, AB will be supplemented by

condom skills building during support group meetings with counselors. Condoms (for those that are sexually

active) will be distributed to adolescents and their adult family members through in-clinic counselors, the

home health team, and clinicians following age-appropriate counseling. Through community outreaches

caretakers of children will be mobilized and provided with health education sessions with special focus on

AB messages. Pediatric health professional trainings will include pediatric HIV counseling issues as part of

its curriculum, whereby abstinence/being faithful messages are discussed. The counseling training will

support health workers; however, the beneficiaries of the PP trainings will be health workers, community

members, and the adolescents and youths themselves. To ensure equitable access to high-quality pediatric

HIV services, satellite sites will be established in peri-urban and rural health care facilities.

Funding for Sexual Prevention: Other Sexual Prevention (HVOP): $350,000

The program will support the expansion of comprehensive HIV/AIDS prevention, care and treatment

services to HIV-infected children and their families and provide pediatric HIV training opportunities for

clinical and ancillary health professionals. Comprehensive HIV services will include antiretroviral therapy

(ART); adherence counseling, TB screening and treatment; diagnosis and treatment of opportunistic

infections (OI); provision of basic preventive care package (BCP); confidential HIV counseling and testing;

family support interventions including prevention with positives and discordant couple counseling for

parents; family psycho-social support; and related interventions for orphans and vulnerable children (OVC).

Following national pediatric treatment guidelines and strategies, in FY08 program initiatives will continue the

care and treatment of pediatric and family member patients and expand quality pediatric care to additional

clients using a family centered approach to ensure the pediatric patients and their families receive related

services and support required for OVCs.

Activities to integrate prevention messages into all care and treatment services will be developed for

implementation by all staff. Specific interventions to support adolescent care, treatment, adherence, and

prevention message will be developed and integrated into clinical and family services. Programming for

‘Other prevention' will be primarily supported through home-based HIV counseling and testing (HBHCT),

health education and "Positive Prevention" messages provided by the health workers either in the home or

the clinic. Health education, counseling and distribution of condoms are components of this prevention

initiative which will focus on the families of HIV-infected children. Condom will be offered through all clinics

and only made available to youth through a counselor or other health professional after a counseling

session. Family Planning (FP) will be provided to women of reproductive age attending the clinics and any

adolescent female identified as sexually active. HBHCT supports family HIV testing and HIV status

disclosure, as well as behavior change and harm reduction counseling. Through Community Care Support

Programs caretakers of children will be mobilized and provided with prevention messages. Measures will

be taken to increase access and utilization of FP services among PIDC adolescents and caretakers.

Sexually Transmitted Diseases (STD) diagnosis and treatment and cervical cancer screening services will

be made available through this program.

The program will support health professional trainings for all cadres (nurses, doctors, counselors etc) to

include pediatric HIV counseling issues as part of its curriculum, and other prevention messages will be

included in the training. It is estimated that such training initiatives will reach no less than 360 health

professionals in the coming year. To ensure equitable access to high-quality pediatric HIV services, satellite

sites will be established in peri-urban and rural health care facilities.

Funding for Care: Adult Care and Support (HBHC): $600,000

The program will support the expansion of comprehensive HIV/AIDS prevention, care and treatment

services to HIV-infected children and their families and provide pediatric HIV training opportunities for

clinical and ancillary health professionals. Comprehensive HIV services will include antiretroviral therapy

(ART); adherence counseling; tuberculosis (TB) diagnosis and treatment; diagnosis and treatment of

opportunistic infections (OI); provision of basic preventive care package (BCP); confidential HIV counseling

and testing; family support interventions including prevention with positives and discordant couple

counseling for parents; family psycho-social support; and related interventions for orphans and vulnerable

children (OVC). Following national pediatric treatment guidelines and strategies, in FY08 program initiatives

will continue the care and treatment of pediatric and family member patients and expand quality pediatric

care to additional clients using a family centered approach to ensure the pediatric patients and their families

receive related services and support required for OVCs. In support of national services and satellite sites

and to ensure full access to high-quality pediatric care and treatment services throughout the country,

initiatives to train and mentor doctors, nurses, counselors, and allied health care providers in the public and

private sector will be established to support basic preventive palliative care, and antiretroviral provision to

children living with HIV/AIDS. The program will participate in the development of the Uganda national

Positive prevention curriculum and provide leadership in area of adolescent care, e.g. disclosure, sex and

sexuality, adolescent counseling.

Through this program, palliative basic HIV care will be provided to all HIV infected children in care (majority

of whom are not yet receiving antiretroviral therapy), HIV exposed infants (infants born to HIV infected

women) for whom a definite HIV diagnosis will be made at 18 months of age, and family members of HIV

infected children. All of these children require regular monitoring for potential disease progression and HIV

disease transmission in the case of the exposed infants. Palliative care services provided will include

prevention and treatment of opportunistic infections, provision of basic preventive care package (comprising

of daily cotrimoxazole for prophylaxis of OIs, insecticide treated mosquito nets for malaria prevention, safe

water systems for diarrhea prevention, micronutrient nutritional supplementation), diagnosis and treatment

of sexually transmitted infections, TB care, and regular assessment of immunological status for ART

eligibility using CD4 testing. HIV exposed infants will be offered HIV testing using DNA-PCR through the

‘early infant diagnosis' program implemented by the MOH. All these children will receive basic palliative

care and will be followed up closely until a definitive HIV diagnosis is made. Children found to be infected

will continue to receive palliative care plus ART if eligible and those found HIV- will be discharged from

these clinics. Staffing, ongoing clinical services (including monitoring investigations, medical supplies and

medications) and training are the primary palliative care/basic care activities. Investigations provided to

children with a definitive HIV diagnosis will include, but are not limited to, baseline TB screening, a baseline

CD4+ count, and follow-up CD4+ counts every 6 months. Additionally, these children benefit from in-clinic

food, food supplements, psychosocial support, cotrimoxazole prophylaxis, multi-vitamins, basic care

package, and any other medications and interventions necessary to reduce opportunities for disease

progression or infection.

In FY08, palliative care/basic care funds will be used to support the activities described above. Home-based

follow-up and HBHCT services will be expanded to include all children and families in care, and not only

those children who are on ART. This expansion will allow for better follow-up of all missing patients and

could potentially lead to reduced mortality. Additionally, linkages and training opportunities with other NGOs

and service organizations developing their pediatric HIV care and treatment capacity will be conducted.

Trainings will take a three-pronged approach, including didactic trainings, practical clinical attachments to

high volume pediatric clinics, and on-site support supervision. It is estimated that no less than 600 health

professionals will participate in these training exercises.

Funding for Care: TB/HIV (HVTB): $300,000

The program will support the expansion of comprehensive HIV/AIDS prevention, care and treatment

services to HIV-infected children and their families and provide pediatric HIV training opportunities for

clinical and ancillary health professionals.

Comprehensive HIV services will include antiretroviral therapy (ART); adherence counseling, TB screening

and treatment; diagnosis and treatment of opportunistic infections (OI); provision of basic preventive care

package (BCP); confidential HIV counseling and testing; family support interventions including prevention

with positives and discordant couple counseling for parents; family psycho-social support; and related

interventions for orphans and vulnerable children (OVC). Following national pediatric treatment guidelines

and strategies, in FY08 program initiatives will continue the care and treatment of pediatric and family

member patients and expand quality pediatric care to additional clients using a family centered approach to

ensure the pediatric patients and their families receive related services and support required for OVCs.

Activities to integrate prevention messages into all care and treatment services will be developed for

implementation by all staff. Specific interventions to support adolescent care, treatment, adherence, and

prevention message will be developed and integrated into clinical and family services. To ensure equitable

access to high-quality pediatric HIV services, satellite sites will be established in peri-urban and rural health

care facilities. In support of national services and satellite sites and to ensure full access to high-quality

pediatric care and treatment services throughout the country, initiatives to train and mentor doctors, nurses,

counselors, and allied health care providers in the public and private sector will be established to support

basic preventive palliative care, and antiretroviral provision to children living with HIV/AIDS.

TB screening and treatment services will be provided for HIV-exposed children, newly diagnosed HIV

infected children, and existing pediatric patients receiving regular palliative care and/ or antiretroviral

therapy (ART). TB screening including a PPD will be performed on all newly diagnosed HIV infected

children. Available data suggests a ~16% PPD reactive rate among newly diagnosed HIV infected pediatric

patients in the existing clinics. Children with reactive PPD but without evidence of active disease will be

provided with isoniazid (INH) preventive treatment (IPT) and followed up closely to ensure adherence and

minimize side effects. During the first 100 days of ART, available clinic data revealed that the risk of

unmasking TB-IRIS at the Pediatric Infectious Diseases clinic (PIDC) increased 2.7 fold compared to pre-

ART (95% CI=2.1 to 2.5; P<.001) and immune reconstitution post-antiretroviral within 6 month of initiating

ART occurred in 6.2% (104/1669) of all patients on ART. Children on ART will therefore be closely

monitored on a monthly basis and evaluated for development of TB. Children with CD4 counts <200 cells/ul

at initiation of ART will have a second PPD placed 6 months later as evidence has shown that such children

had a 41% longer time to TB unmasking, implying a longer time was needed for restoration of antigen-

specific immunity. Transport reimbursement will be provided to needy clients to return for PPD reading at

the clinic (It is estimated that 22% [~555] patients will need such assistance). TB screening will be extended

to family members of all PPD reactive children.

Children who are symptomatic for TB will be actively evaluated using clinical assessment, sputum smears,

and radiological examination. Children found to have active TB will be treated according to the national

guidelines provided by MOH/NTLP for management of TB in children. Anti-TB drugs/ medications will be

provided through the National TB and Leprosy Program. At the same time, children will be assessed for

ART eligibility using WHO clinical staging and CD4 where available. For those that are co-infected with TB

and HIV, ART will be initiated at CD4 <350 in line with the revised National ART guidelines. For patients

requiring concurrent administration of anti-TB and antiretroviral therapy, precautions will be taken to

minimize toxicity and drug interactions and ensure adherence. For children with TB and HIV who are not yet

ART eligible, treatment for TB will be administered and the patient revaluated at the end of treatment for

ART eligibility. All children will receive cotrimoxazole prophylaxis as part of basic palliative basic care and

will be followed up regularly. In FY08, palliative TB/HIV care activities will continue at the existing Mulago

PIDC and its satellite clinics in Kampala and services will be expanded to reach rural district clinics and

health centers to provide TB screening and treatment services. It is estimated that >2500 children will have

a PPD performed in FY08. Approximately 16% of those screened with a PPD will be reactive or have

symptoms suggestive of TB and will, therefore, have chest x-rays performed. Of the existing 5000 HIV

infected children in active follow-up by end of June 2007, plus the patients recruited by March 2008, it is

estimated that >336 will require TB treatment.

No less than 360 health professionals will be trained in TB/HIV through this program. Training will strive to

enhance the knowledge and expertise of health professionals in diagnosis, care, and treatment of children

co-infected with TB/HIV as TB has a significant effect on morbidity, mortality and ARV drug treatment

options and outcomes. Appropriate pediatric diagnostic techniques and treatment options/interactions will

be emphasized through these training efforts.

Funding for Care: Orphans and Vulnerable Children (HKID): $300,000

The program will support the expansion of comprehensive HIV/AIDS prevention, care and treatment

services to HIV-infected children and their families and provide pediatric HIV training opportunities for

clinical and ancillary health professionals.

Comprehensive HIV services will include antiretroviral therapy (ART); adherence counseling, TB screening

and treatment; diagnosis and treatment of opportunistic infections (OI); provision of basic preventive care

package (BCP); confidential HIV counseling and testing; family support interventions including prevention

with positives and discordant couple counseling for parents; family psycho-social support; and related

interventions for orphans and vulnerable children (OVC). Following national pediatric treatment guidelines

and strategies, in FY08 program initiatives will continue the care and treatment of pediatric and family

member patients and expand quality pediatric care to additional clients using a family centered approach to

ensure the pediatric patients and their families receive related services and support required for OVCs.

Activities to integrate prevention messages into all care and treatment services will be developed for

implementation by all staff. Specific interventions to support adolescent care, treatment, adherence, and

prevention message will be developed and integrated into clinical and family services. To ensure equitable

access to high-quality pediatric HIV services, satellite sites will be established in peri-urban and rural health

care facilities. In support of national services and satellite sites and to ensure full access to high-quality

pediatric care and treatment services throughout the country, initiatives to train and mentor doctors, nurses,

counselors, and allied health care providers in the public and private sector will be established to support

basic preventive palliative care, and antiretroviral provision to children living with HIV/AIDS.

Majority of children attending pediatric HIV care clinics are orphaned (~54% of the children seen at the

PIDC have lost one or more biological parent). Additionally, 66% have baseline weight and height less than

the 2.5th centile indicating inadequate nutrition, while others are deemed vulnerable simply due to their HIV

positive status, guardian's low household income, and lack of access to education. Hence, all children

attending pediatric HIV care clinics are considered vulnerable. This program will support provision of

specialized OVC services including play therapy, psychosocial support, health care, and nutritional support.

In FY08, more than 9,000 HIV+ children will benefit from OVC services. Vulnerable adolescents will benefit

services such as nutritional support, technical and life skills training. Children in need of OVC services that

may not be available through this program for example legal services and school fees support will be

referred to other providers.

Funding for Testing: HIV Testing and Counseling (HVCT): $250,000

The program will support the expansion of comprehensive HIV/AIDS prevention, care and treatment

services to HIV-infected children and their families and provide pediatric HIV training opportunities for

clinical and ancillary health professionals.

Comprehensive HIV services will include antiretroviral therapy (ART); adherence counseling, TB screening

and treatment; diagnosis and treatment of opportunistic infections (OI); provision of basic preventive care

package (BCP); confidential HIV counseling and testing; family support interventions including prevention

with positives and discordant couple counseling for parents; family psycho-social support; and related

interventions for orphans and vulnerable children (OVC). Following national pediatric treatment guidelines

and strategies, in FY08 program initiatives will continue the care and treatment of pediatric and family

member patients and expand quality pediatric care to additional clients using a family centered approach to

ensure the pediatric patients and their families receive related services and support required for OVCs.

Activities to integrate prevention messages into all care and treatment services will be developed for

implementation by all staff. Specific interventions to support adolescent care, treatment, adherence, and

prevention message will be developed and integrated into clinical and family services. To ensure equitable

access to high-quality pediatric HIV services, satellite sites will be established in peri-urban and rural health

care facilities. In support of national services and satellite sites and to ensure full access to high-quality

pediatric care and treatment services throughout the country, initiatives to train and mentor doctors, nurses,

counselors, and allied health care providers in the public and private sector will be established to support

basic preventive palliative care, and antiretroviral provision to children living with HIV/AIDS.

HIV Counseling and Testing (HCT) will be provided in several forms: 1) early diagnosis of children below 18

months of age with DNA-PCR; 2) Voluntary Counseling and Testing (VCT) for children 18 months to 18

years using EIA antibody testing; 3) in clinic HIV counseling and testing of family/household members of

clients attending the clinic ;4) home-based HIV counseling and testing of family/household members

(HBHCT) of index patients; and, 5) Community-based HIV counseling and testing in the rural eastern and

western regional districts where such services are currently lacking. DNA-PCR testing at the regional

referral hospitals will be supported through the MOH in collaboration with JCRC and is aimed at improving

early infant diagnosis of HIV nationwide. The target populations that will benefit from these services include

vulnerable infants, children and youth, and adults in HIV/AIDS-affected families. The MOH has developed

infant and early HIV diagnosis guidelines and monitoring tools that are going to be disseminated to all

providers in the coming year. HIV exposed infants are identified in the postnatal, immunization, and other

child clinics are screened for HIV infection at 6 weeks (or earliest contact between 6 weeks and 18 months)

using DNA-PCR testing. Blood specimens for DNA-PCR are collected using Dried Blood Spot (DBS)

technique and transported to the regional referral laboratories for testing. HIV infected infants are linked to

palliative and ART services while the HIV negative have enhanced prevention messages during post test

counseling. Specialized infant feeding counseling messages are provided to HIV+ mothers who continue to

breastfeed their HIV- infants to reduce future possibilities for HIV transmission to the infant.

In FY08, it is estimated that approximately 38,000 children and adults will be screened for HIV through

various urban and rural clinics. More than 9,500 of the 38,000 screened are anticipated to be infants <18

months. These infants will require DNA-PCR testing. In line with HIV counseling and testing (HCT) policy of

2005, the program will also support the roll-out of Pediatric HIV routine counseling and testing (RCT) in all

the facilities in Uganda. Additionally, linkages and training opportunities with other NGOs and service

organizations to assist in the development of pediatric HIV counseling and testing capacity will be

conducted. For these capacity building initiatives, it is estimated that approximately 600 health professionals

will be trained. The program will contribute to the development of pediatric counseling and testing expertise

throughout the country. Health professionals will benefit from pediatric-specific HIV/AIDS training and

capacity building in the form of didactic trainings, support supervision, and clinical attachments to high

volume pediatric HIV specialty centers like the Mulago PIDC. Through the UNICEF/Clinton Foundation

collaboration, IEC materials aimed at informing the population on linking PMTCT to HIV care and infant

feeding are being designed.

Funding for Treatment: ARV Drugs (HTXD): $2,706,832

The program will support the expansion of comprehensive HIV/AIDS prevention, care and treatment

services to HIV-infected children and their families and provide pediatric HIV training opportunities for

clinical and ancillary health professionals.

Comprehensive HIV services will include antiretroviral therapy (ART); adherence counseling, TB screening

and treatment; diagnosis and treatment of opportunistic infections (OI); provision of basic preventive care

package (BCP); confidential HIV counseling and testing; family support interventions including prevention

with positives and discordant couple counseling for parents; family psycho-social support; and related

interventions for orphans and vulnerable children (OVC). Following national pediatric treatment guidelines

and strategies, in FY08 program initiatives will continue the care and treatment of pediatric and family

member patients and expand quality pediatric care to additional clients using a family centered approach to

ensure the pediatric patients and their families receive related services and support required for OVCs.

Activities to integrate prevention messages into all care and treatment services will be developed for

implementation by all staff. Specific interventions to support adolescent care, treatment, adherence, and

prevention message will be developed and integrated into clinical and family services. To ensure equitable

access to high-quality pediatric HIV services, satellite sites will be established in peri-urban and rural health

care facilities. In support of national services and satellite sites and to ensure full access to high-quality

pediatric care and treatment services throughout the country, initiatives to train and mentor doctors, nurses,

counselors, and allied health care providers in the public and private sector will be established to support

basic preventive palliative care, and antiretroviral provision to children living with HIV/AIDS.

HIV Counseling and Testing (HCT) will be provided in several forms: 1) early diagnosis of children below 18

months of age with DNA-PCR; 2) Voluntary Counseling and Testing (VCT) for children 18 months to 18

years using EIA antibody testing; 3) in clinic HIV counseling and testing of family/household members of

clients attending the clinic ;4) home-based HIV counseling and testing of family/household members

(HBHCT) of index patients; and, 5) Community-based HIV counseling and testing in the rural eastern and

western regional districts where such services are currently lacking. DNA-PCR testing at the regional

referral hospitals will be supported through the MOH in collaboration with JCRC and is aimed at improving

early infant diagnosis of HIV nationwide. The target populations that will benefit from these services include

vulnerable infants, children and youth, and adults in HIV/AIDS-affected families. The MOH has developed

infant and early HIV diagnosis guidelines and monitoring tools that are going to be disseminated to all

providers in the coming year. HIV exposed infants are identified in the postnatal, immunization, and other

child clinics are screened for HIV infection at 6 weeks (or earliest contact between 6 weeks and 18 months)

using DNA-PCR testing. Blood specimens for DNA-PCR are collected using Dried Blood Spot (DBS)

technique and transported to the regional referral laboratories for testing. HIV infected infants are linked to

palliative and ART services while the HIV negative have enhanced prevention messages during post test

counseling. Specialized infant feeding counseling messages are provided to HIV+ mothers who continue to

breastfeed their HIV- infants to reduce future possibilities for HIV transmission to the infant.

In FY08, it is estimated that approximately 38,000 children and adults will be screened for HIV through

various urban and rural clinics. More than 9,500 of the 38,000 screened are anticipated to be infants <18

months. These infants will require DNA-PCR testing. In line with HIV counseling and testing (HCT) policy of

2005, the program will also support the roll-out of Pediatric HIV routine counseling and testing (RCT) in all

the facilities in Uganda. Additionally, linkages and training opportunities with other NGOs and service

organizations to assist in the development of pediatric HIV counseling and testing capacity will be

conducted. For these capacity building initiatives, it is estimated that approximately 600 health professionals

will be trained. The program will contribute to the development of pediatric counseling and testing expertise

throughout the country. Health professionals will benefit from pediatric-specific HIV/AIDS training and

capacity building in the form of didactic trainings, support supervision, and clinical attachments to high

volume pediatric HIV specialty centers like the Mulago PIDC. Through the UNICEF/Clinton Foundation

collaboration, IEC materials aimed at informing the population on linking PMTCT to HIV care and infant

feeding are being designed.

Funding for Treatment: Adult Treatment (HTXS): $2,065,771

The program will support the expansion of comprehensive HIV/AIDS prevention, care and treatment

services to HIV-infected children and their families and provide pediatric HIV training opportunities for

clinical and ancillary health professionals.

Comprehensive HIV services will include antiretroviral therapy (ART); adherence counseling, TB screening

and treatment; diagnosis and treatment of opportunistic infections (OI); provision of basic preventive care

package (BCP); confidential HIV counseling and testing; family support interventions including prevention

with positives and discordant couple counseling for parents; family psycho-social support; and related

interventions for orphans and vulnerable children (OVC). Following national pediatric treatment guidelines

and strategies, in FY08 program initiatives will continue the care and treatment of pediatric and family

member patients and expand quality pediatric care to additional clients using a family centered approach to

ensure the pediatric patients and their families receive related services and support required for OVCs.

Activities to integrate prevention messages into all care and treatment services will be developed for

implementation by all staff. Specific interventions to support adolescent care, treatment, adherence, and

prevention message will be developed and integrated into clinical and family services. To ensure equitable

access to high-quality pediatric HIV services, satellite sites will be established in peri-urban and rural health

care facilities. In support of national services and satellite sites and to ensure full access to high-quality

pediatric care and treatment services throughout the country, initiatives to train and mentor doctors, nurses,

counselors, and allied health care providers in the public and private sector will be established to support

basic preventive palliative care, and antiretroviral provision to children living with HIV/AIDS.

Only 30 out of 220 accredited antiretroviral therapy (ART) sites provide pediatric services (report of National

Strategic Framework evaluation 2001-2006 of June 2007). Challenges related to pediatric ART include high

cost of pediatric ARVs, inadequate skills, and limited resources for diagnosis of HIV in children. This activity

will strengthen capacity for pediatric ART scale-up to several rural districts. The program will conduct

training for capacity building in ART delivery through didactic methods, clinical attachment, and mentoring

and support supervision to reach 600 health care providers. The program will work closely with the PMTCT

program and the national early infant diagnosis to identify HIV infected children. ARV Services will

emphasize clinical support and care and treatment monitoring to an estimated 5000 children and their

parents already receiving care at the various established pediatric clinics. ARV services will include

screening for ART eligibility using WHO and MOH national guidelines. Eligible patients and their carers will

then receive preparatory counseling focusing on adherence to ART and regular follow-up of patients

ensured. Commodity procurement, opportunistic infection treatment and ART monitoring investigations,

adherence support and follow-up, personnel, quality assurance and monitoring and evaluation of

programming associated with the children and family members on ART will also be covered under this

funding. Adherence follow-up and monitoring will be accomplished through enhanced in-clinic counseling

and home health services.

It is estimated that no less than 360 health professionals will participate in pediatric-specific training

activities supported through this program. Increased numbers of children and families will benefit from

quality pediatric HIV care and treatment services through these trainings and capacity building sharing of

best practices.

Funding for Laboratory Infrastructure (HLAB): $500,000

The program will support the expansion of comprehensive HIV/AIDS prevention, care and treatment

services to HIV-infected children and their families and provide pediatric HIV training opportunities for

clinical and ancillary health professionals. Comprehensive HIV services will include antiretroviral therapy

(ART); adherence counseling, TB screening and treatment; diagnosis and treatment of opportunistic

infections (OI); provision of basic preventive care package (BCP); confidential HIV counseling and testing;

family support interventions including prevention with positives and discordant couple counseling for

parents; family psycho-social support; and related interventions for orphans and vulnerable children (OVC).

Following national pediatric treatment guidelines and strategies, in FY08 program initiatives will continue the

care and treatment of pediatric and family member patients and expand quality pediatric care to additional

clients using a family centered approach to ensure the pediatric patients and their families receive related

services and support required for OVCs. Activities to integrate prevention messages into all care and

treatment services will be developed for implementation by all staff. Specific interventions to support

adolescent care, treatment, adherence, and prevention message will be developed and integrated into

clinical and family services.

The program will support the strengthening of laboratory services for diagnosis of HIV, diagnosis of

opportunistic infections (OI), assessment for ART eligibility, immunological monitoring for antiretroviral

therapy (ART), diagnosis of sexually transmitted infections, and evaluation of patients in care through

hematological and chemistry testing. Several HIV testing initiatives will be supported in order to identify

more children and link them to appropriate HIV care services. These will include VCT for those referred to

the clinics, home based HIV testing attending clinics, Home based HIV testing offered to family members of

HIV infected children (HBHCT), and routine HIV tesing and counseling (RTC) for hospitalized children.

Children below 18 months of age will be tested for HIV using virologic DNA-PCR techniques that will be

made available at the regional referral hospital laboratories through support from the MOH. The MOH has

developed guidelines for the implementation of the ‘early infant diagnosis program' that aims at identifying

HIV-infected infants and linking them to palliative care services at the earliest opportunity. Dried Blood spot

(DBS) blood specimens collected from infants at 6 weeks of age attending post-natal or immunization clinics

will be transported to the regional laboratories for testing. For older children above 18 months of age and

family members of HIV- infected children will be tested for HIV using EIA tests or rapid test kits. The

program will support laboratory services for 5000 children in the existing clinics at PIDC Kampala and

several other satellites located in rural and urban areas as pediatric services are scaled up. All clinics will

provide services in HIV palliative care, tuberculosis (TB) care, (ART), OI care and management of sexually

transmitted infections (STI).

To ensure equitable access to high-quality pediatric HIV services, satellite sites will be established in peri-

urban and rural health care facilities. In support of national services and satellite sites and to ensure full

access to high-quality pediatric care and treatment services throughout the country, initiatives to train and

mentor doctors, nurses, counselors, and allied health care providers in the public and private sector will be

established to support basic preventive palliative care, and antiretroviral provision to more children living

with HIV/AIDS. A minimum of 12 health workers will be trained in the provision of laboratory services.