Detailed Mechanism Funding and Narrative

Years of mechanism: 2007 2008 2009

Details for Mechanism ID: 5342
Country/Region: Uganda
Year: 2008
Main Partner: Catholic Relief Services
Main Partner Program: NA
Organizational Type: FBO
Funding Agency: HHS/HRSA
Total Funding: $6,264,675

Funding for Treatment: ARV Drugs (HTXD): $3,094,749

AIDSRelief provides a comprehensive care and treatment program emphasizing strong links between

PLHAs, their family, communities and the health institutions. Its goal is to ensure that people living with

HIV/AIDS have access to Antiretroviral Therapy (ART) and quality medical care.

AIDSRelief is a consortium of five organizations which includes Catholic Relief Services (CRS) working as

the lead agency, the Institute of Human Virology (IHV), Constella Futures Group (CF), Catholic Medical

Mission Board (CMMB) and Interchurch Medical Assistance World Health (IMA); AIDSRelief services are

offered through 15 Local Partner Treatment Facilities (LPTFs), distributed throughout Uganda working in

some of the most underserved and rural areas, including Northern Uganda. These include St. Mary's Lacor,

St Joseph Kitgum, Nsambya Hospital, , Kamwokya Christian Caring Community, Family Hope Center

Kampala, Family Hope Center Jinja,, WTC Kololo, Virika Hospital, Villa Maria Hospital, Kabarole Hospital,

Bushenyi Medical Center 1- Katungu, Bushenyi Medical Center 2- Kabwohe, Kyamuhunga Comboni

Hospital, Kasanga Health Centre and Kalongo Hospital. In order to get services closer to the communities it

serves, AIDSRelief supports 26 satellite sites in selected LPTFs. The Children's AIDS Fund is a sub-

grantee in AIDSRelief and manages a number of the LPTFS. AIDSRelief is planning to activate 4 additional

LPTFs and phase out 1 LPTF in this grant year. As of June 30, 2007, AIDSRelief in Uganda was providing

care and support to 46,500 patients and antiretroviral treatment to 12,700 HIV-infected people of which 877

are children.

AIDSRelief has developed and improved the supply chain management capacity of the 15 sites it supports.

AIDSRelief procures Antiretroviral drugs (ARV) through a global procurement mechanism which provides

very competitive pricing, with delivery, warehousing and distribution through Joint Medical Stores (JMS).

This collaboration builds and strengthens the existing distribution network that specifically works for faith-

based healthcare facilities in Uganda. In year 4, AIDSRelief received drugs from Clinton Foundation which

enabled the program to scale up treatment despite the flat-lined budget.

Standard Operating Procedures (SOPs) have been developed in accordance with national guidelines that

guide supply chain activities from product selection, forecasting, procurement and consumption monitoring.

AIDSRelief has ensured excellent supply chain management and uninterrupted ARVs provision through

local capacity building at critical points within the supply management chain. In addition, the program has

implemented an ARV dispensing software developed by MSH RPM Plus enabling LPTFs to track the use of

ARVs; this dispensing tool has enabled LPTFs to enter accurate pharmacy data, forecast drug needs,

monitor patient numbers on ARVs and generate accurate pharmacy reports and initiate appropriate stock

replenishment. These reports, used to track inventory movement through the chain, permit continuous

modulation of patient enrollment to reflect ARV drugs availability and ensure a guaranteed and continuous

supply of drugs for each patient initiated on therapy.

In FY08, AIDSRelief will expand its services to 5 new LPTFs and 11 satellite sites with the goal to reach

23,618 patients on ART, of which 2,834 will be children, and 54,813 patients in care and support. This

request will provide ARVs for 6,608 patients. The program will leverage additional resources for ARVs from

other donors such as the Clinton Foundation, but will cover other ART related support such as purchase of

OI drugs, laboratory supplies and technical assistance to the LPTFs. At the end of Year 5, AIDSRelief will

be supporting a total of 23 LPTFs and 37 satellites.

The program will continue to procure adult 1st line, alternative 1st line, and 2nd line therapies for adults and

children. The AIDSRelief Supply Chain Management Team will assist with capacity building, technical

backstopping and on-going training in supply chain logistic management which includes forecasting, stock

management, standard operating procedures and use of ART Dispensing Tool at the LPTF level. This will

turn the supply situation into a pull system; AIDSRelief has and will continue to support its sites with

frequent on-site mentoring, quarterly partner forums and access to a web based site on which difficult cases

can be discussed. This process is designed to provide LPTFs with ongoing clinical technical assistance

and to keep them abreast with the latest developments in HIV patient care. Therapeutic Drug Committees

will continue to be rolled out from the country program level to all LPTFs and this will further improve

management and forecasting of drugs for better patient outcomes. Technical assistance will also be

provided to laboratory, finance and monitoring and evaluation staff.

The Institute for Human Virology will participate in the periodic review of National Treatment Guidelines in

order to assist in the selection of regimens most appropriate to the Ugandan context. Choice of regimen is

guided by most recent evidence to ensure that the most effective and durable regimen available within the

national guidelines with the possible toxicity and resistance profile is used. The current choice of primary

regimen for AIDSRelief sites consists of Truvada (TVD) combined with Nevirapine (NVP) or Efavirenz (EFV)

for patients on Rifampicin containing tuberculosis protocols or intolerant to NVP. Aluvia (lopinavir/ritonovir)

is used for those who are intolerant to both NVP and EFV. For those who have renal insufficiency,

AZT/3TC will be substituted for TVD. Limited quantities of Stavudine (D4T) to be combined with

Lamivudine (3TC) are also procured to be used for patients with both renal insufficiency and anemia. The

choice of regimen is based on the more favorable pharmacokinetic and safety profile and is supported by

extensive clinical evidence. The choice of regimen is also designed to preserve optimal therapeutic choices

for second line regimens, which in the AR program consists of AZT (or D4T in cases of anemia, or TDF in

patients failing AZT or D4T as their primary regimen) coupled with 3TC and Aluvia. All drugs with exception

of TVD and Aluvia (which are currently not available as generics) are procured in generic form. AIDSRelief

provides AZT, 3TC and NVP for children less than 5 years of age, and D4T, 3TC and EFV/NVP for those

above 5 years and ABC as an alternative for those affected by severe anemia.

AIDSRelief will continue to work closely with the Ugandan Ministry of Health (MOH), the USG team in-

country, and other partners and programs to harmonize and strengthen pharmaceutical supply chain

systems. It will coordinate with other procurement and treatment agencies to ensure that LPTFs have

access to a stable chain of supply and no occurrence of any stock outs.

Coordinated by Constella Futures, strategic information (SI) activities incorporate program level reporting,

enhancing the effectiveness and efficiency of both paper-based and computerized patient monitoring and

management (PMM) systems, assuring data quality and continuous quality improvement, and using SI for

program decision making across all LPTFs. AIDSRelief has built a strong PMM system using in-country

networks and available technology at 15 LPTFs in COP07. In COP08, Constella Futures will work with the

new sites and also carry out site visits to all LPTFs to provide technical assistance that will ensure

continued quality data collection, data entry, data validation and analysis, and dissemination of findings

across a range of stakeholders. It will ensure compilation of complete and valid HIV patient treatment/ARV

data; enhance analysis of required indicators for quality HIV patient treatment and ARV program monitoring

and reporting; and provide relevant, LPTF-specific technical assistance to develop specific data quality

improvement plans. In year 5, AIDSRelief will support LPTFs roll out of IQCare, an electronic data

management software deployed in COP'07, to enhance sustainability of PMM systems. The program will

promote these systems through a Training of Trainers (TOT) and peer to peer training model in SI, where

"expert" LPTF staff will train others in various skills. AIDSRelief will promote the data use culture, to enable

Activity Narrative: LPTFs use data for informed clinical decisions and adaptive management. It will ensure that different data

systems at health facilities are harmonized for effective and efficient reporting.

AIDSRelief developed a sustainability plan in Year 4 focusing on technical, organizational, funding, policy

and advocacy dimensions. To date, the program has been able to increase access to quality care and

treatment, while simultaneously strengthening health facility systems through human resource support,

equipment, financial training and improvements in health management information. In COP08, the program

will further build on this foundation to closely work and collaborate with Makarere University Department of

Nursing and other nursing schools attached to the LPTFs to incorporate comprehensive HIV/AIDS training

modules into existing curricula. The program will also support linkages between LPTFs and the MOH to tap

into locally available training institutions. These approaches will ensure continuity of skills training.

AIDSRelief will particularly focus on its relationship with indigenous organizations such as the Uganda

Catholic Medical Bureau and Uganda Protestant Medical Bureau to build their institutional capacity to

support LPTFs integrate ART and other care and support programs into their health care services. These

strategies will enable AIDSRelief to fully transfer its knowledge, skills and responsibilities to in country

service providers as part of the program's sustainability plan.

Funding for Treatment: Adult Treatment (HTXS): $3,169,926

AIDSRelief provides a comprehensive care and treatment program emphasizing strong links between

PLHAs, their family, communities and health institutions. Its goal is to ensure that people living with

HIV/AIDS have access to Antiretroviral Therapy (ART) and quality medical care.

AIDSRelief is a consortium of five organizations which includes Catholic Relief Services (CRS) working as

the lead agency, the Institute of Human Virology (IHV), Constella Futures Group (CF), Catholic Medical

Mission Board (CMMB) and Interchurch Medical Assistance World Health (IMA); AIDSRelief services are

offered through 15 Local Partner Treatment Facilities (LPTFs), distributed throughout Uganda working in

some of the most underserved and rural areas, including Northern Uganda. These include St. Mary's Lacor,

St Joseph Kitgum, Nsambya Hospital, Kamwokya Christian Caring Community, Family Hope Center

Kampala, Family Hope Center Jinja, Virika Hospital, Villa Maria Hospital, Kabarole Hospital, Bushenyi

Medical Center 1- Katungu, Bushenyi Medical Center 2- Kabwohe, Kyamuhunga Comboni Hospital,

Kasanga Health Centre and Kalongo Hospital. In order to get services closer to the communities it serves,

AIDSRelief supports 26 satellite sites in selected LPTFs. The Children's AIDS Fund is a sub-grantee in

AIDSRelief and manages a number of the LPTFS. AIDSRelief is planning to activate 4 additional LPTFs

and phase out 1 LPTF in this grant year. As of June 30, 2007, AIDSRelief in Uganda was providing care

and support to 46,500 patients and antiretroviral treatment to 12,700 HIV-infected people of which 877 are

children.

In FY08, AIDSRelief will expand its services to 5 new LPTFs and 11 satellite sites with the goal to reach

23,618 patients on ART, of which 2,834 will be children, and 54,813 patients in care and support. This

request will provide ARVs for 6,608 patients. The program will leverage additional resources for ARVs from

other donors such as the Clinton Foundation, but will cover associated ART related support such as

purchase of OI drugs, laboratory supplies and technical assistance to the LPTFs. At the end of Year 5,

AIDSRelief will be supporting a total of 23 LPTFs and 37 satellites.

The program will continue to provide comprehensive assistance to LPTFs. This includes training and on-site

mentorship of medical staff, strengthening of HIV/AIDS community outreach activities, quality

assurance/quality improvement of HIV services, strategic information, capacity building of management and

financial staff, provision of opportunistic infection drugs, medical supplies and laboratory reagents, and staff

and minor infrastructure support. The decentralization of HIV services through 37 satellite sites will increase

accessibility of such services to those who live in remote areas. This approach reinforces AIDSRelief's care

model with communities, satellite sites and LPTFs strongly interlinked by health providers and community

volunteers in order to meet the need of HIV/AIDS patients. AIDSRelief technical staff with significant

experience in this area will assist local partners in improving community nursing support, building

community health teams, and establishing clinic feedback mechanisms. Hands-on training of trainers will

replicate the model throughout the AIDSRelief network, an effort which will have positive benefits for

surrounding communities and treatment programs.

AIDSRelief, because of its work through partners who are firmly embedded within communities, has the

ability to support involvement of communities. AIDSRelief supported facilities are currently providing varying

levels of home based care and community preventative services. Further development of these community

health programs to provide integrated HIV care and preventative services is critical to ensuring sustainable

treatment programs and maximizing funding investments. Community health programs will be structured to

promote family based care through disclosure counseling, secondary prevention, and family based testing

and education. In addition, motivated patients who make up most of the LPTFs' community volunteers will

be used as resource to support patients on therapy, disseminate HIV care and prevention literacy.

AIDSRelief will adapt existing, locally appropriate Information Education and Communication (IEC) and

Behavior Change Communication (BCC) materials, as well as to identify gaps in these media and develop

materials as needed to be used by health workers and community volunteers.

AIDSRelief will assist LPTF networks with PLHA groups serving as volunteers in the community to

strengthen adherence programs, which have been demonstrated to be a key component of good clinical

outcomes. Emphasizing the importance of adherence and community linkages at all AIDSRelief supported

sites has enabled the program to achieve high and durable viral suppression. The program will also

strengthen linkages within the LPTFs, particularly those between PMTCT, TB and CT services with ART

services. Emphasis will also be given to build capacity and develop strong linkages with the satellite sites

and other community interventions. LPTFs external and internal integration will be reinforced so that core

AIDSRelief care and treatment activities will be integrated with ancillary services and program activities of

other providers in the same region. A total of 290 facility level staff and 720 community volunteers will be

given comprehensive HIV/AIDS training enabling them to fulfill their responsibilities. AIDSRelief will follow-

up classroom-based training with on site clinical mentorship for clinicians and site level support for other

cadres of workers. Regional CME and quarterly partners' forums will complement LPTF's staff training,

allow experience sharing and reinforce knowledge and skill transfer from AIDSRelief technical staff.

Task shifting to maximize human resources will be emphasized at facility and community levels. At the

LPTFs, the strategy will be based on using nurses and clinical officers for the routine follow-up of stable

patients, using protocol driven nurse and clinical officer management of non-critical acute symptoms and

using nurses and pharmacists for routine medication dispensing to stable patients. At the community level,

AIDSRelief will encourage the development of community based satellite clinics staffed by clinical

officers/nurses/community health workers for the routine care of stable patients and the use of community

health teams for the delivery of home based care and for medication delivery.

AIDSRelief will continue to strengthen the health system management of LPTFs. The program will conduct

biannual finance and compliance trainings and program finance staff will carry out regular site visits to

provide technical assistance. LPTF trained finance staff in key internal control operations will be able to set

up appropriate cost accounting systems and adopt a program budgeting approach. LPTFs will also be

assisted to develop a more efficient organizational management structure.

Coordinated by Constella Futures, strategic information (SI) activities incorporate program level reporting,

enhancing the effectiveness and efficiency of both paper-based and computerized patient monitoring and

management (PMM) systems, assuring data quality and continuous quality improvement, and using SI for

program decision making across all LPTFs. AIDSRelief has built a strong PMM system using in-country

networks and available technology at 15 LPTFs in COP07. In COP08, Constella Futures will carry out site

visits to provide technical assistance that will ensure continued and improved quality data collection, data

entry, data validation and analysis, and dissemination of findings across a range of stakeholders. It will

ensure compilation of complete and valid HIV patient treatment/ARV data; enhance analysis of required

indicators for quality HIV patient treatment and ARV program monitoring and reporting; and provide

relevant, LPTF-specific technical assistance to develop site specific data quality improvement plans. In year

5, AIDSRelief will support the roll out of IQCare, an electronic data management software deployed in

COP'07, which will enhance sustainability of PMM systems. The program will promote these systems

through a Training of Trainers (TOT) and a peer to peer training model, where "expert" LPTF staff will train

Activity Narrative: others in various skills. AIDSRelief will promote the data use culture to enable LPTFs to use data for

informed clinical decisions and adaptive management.

AIDSRelief developed a sustainability plan in Year 4 focusing on technical, organizational, funding, policy

and advocacy dimensions. To date, the program has been able to increase access to quality care and

treatment, while simultaneously strengthening health facility systems through human resource support,

equipment, financial training and improvements in health management information. In COP08, the program

will further build on this foundation to closely work and collaborate with Makarere University Department of

Nursing and other nursing schools attached to the LPTFs to incorporate comprehensive HIV/AIDS training

modules into existing curricula. The program will also support linkages between LPTFs and the MOH to tap

into locally available training institutions. These approaches will ensure continuity of skills training.

AIDSRelief will particularly focus on its relationship with indigenous organizations such as the Uganda

Catholic Medical Bureau and Uganda Protestant Medical Bureau to build their institutional capacity and to

support LPTFs integration of ART and other care and support programs into their health care services.

These strategies will enable AIDSRelief to fully transfer its knowledge, skills and responsibilities to in

country service providers as part of the program's sustainability plan.

Subpartners Total: $2,903,076
Kamwokya Christian Caring Community: $142,618
St. Mary's Hospital, Lacor: $117,264
Comboni Samaritans of Gulu : $107,756
Christian HIV/AIDS Prevention and Support: $19,016
Meeting Point: $19,016
Virika Hospital: $107,756
Villa Maria Hospital: $104,587
Kabarole Hospital: $76,063
Kyamuhanga Comboni Hospital: $85,571
Kalongo Hospital: $69,725
Katungu Medical Center: $57,047
Kabwohe Medical Center: $85,571
Kasanga Health Center: $98,248
Palladium Group (formerly Futures Group): $209,174
Children's AIDS Fund International: $266,221
University of Maryland: $592,658
Nsambya Hospital: $221,851
Nyenga Hospital: $38,032
Kasana Luwero Diocese: $22,185
Amai Community Hospital: $22,185
Not Identified: $367,638
St. Joseph's Hospital: $72,894