Detailed Mechanism Funding and Narrative

Details for Mechanism ID: 4341
Country/Region: Rwanda
Year: 2007
Main Partner: National Reference Laboratory - Rwanda
Main Partner Program: NA
Organizational Type: Host Country Government Agency
Funding Agency: HHS/CDC
Total Funding: $500,000

Funding for Biomedical Prevention: Prevention of Mother to Child Transmission (MTCT): $100,000

This activity will renovate laboratory work areas at the Central University Hospital in Butare, allowing it to become only the second reference laboratory in Rwanda capable of performing PCR testing for early infant HIV diagnosis. This proposed activity addresses an oversight in COP 2007 planning: PCR equipment and reagents were funded in COP 2007 to equip this laboratory; however funds were not allocated for the renovations needed. This activity helps expand integrated PMTCT, early infant diagnosis and pediatric care and treatment services into the south and southwest parts of Rwanda.

Table 3.3.01:

Funding for Laboratory Infrastructure (HLAB): $400,000

This activity relates to activities in HLAB (7262, 7172, 7154, 8189).

In FY 2006, the EP developed a cooperative agreement with the NRL to begin direct funding of certain key reference laboratory functions. As the lead institution in Rwanda's national laboratory network, the NRL plays a critical role in the successful expansion of HIV prevention, diagnostic, care and treatment services nationally. The NRL has been a close collaborator in EP efforts for many years, and has benefited from EP technical and financial support through several implementing partners. As outlined in the Rwanda EP five-year strategy, FY 2006 marked the beginning of a shift toward direct EP funding to NRL. Substantial resources have already been invested in NRL by CDC and Columbia UTAP support for infrastructure, technical activities, and management capacity. Support will continue in FY 2007 through CDC direct technical support, Columbia UTAP long-term technical advisors, and through continued funding of this cooperative agreement (at the time of writing, the cooperative agreement had not yet been awarded to NRL).

NRL cooperative agreement activities in FY 2006 include support for human resources (technical positions and training), infrastructure maintenance, and select QA activities. One-time additional funds were added to the cooperative agreement in FY 2006 for procurement of CD4 supplies, equipment and kits, as well as to support the logistics of maintaining the network of CD4 laboratories. In FY 2007, NRL activities will again focus on selected infrastructure maintenance, human resources, and QA activities.

Among its infrastructure-related activities, NRL will expand PCR testing capacity to a second reference laboratory in Butare to support the expanding early infant diagnosis program. NRL cooperative agreement funds will support the renovations needed to prepare this laboratory and the training of Butare staff. The NRL will also continue a maintenance contract for all of its central-level equipment through the MOH maintenance unit, as well as conduct small repairs and preventive maintenance in the ART site laboratories, secure warehouse storage space, and transport laboratory equipment and reagents to sites.

NRL will support technical staff needed to carry out surveillance and M&E activities that have laboratory components, such as ANC sentinel surveillance and the national ART program evaluation activities. A modest amount of funding will be made available to support participation of key senior technical staff in international trainings and conferences directly relevant to increasing capacity for HIV-related laboratory techniques.

Throughout the national laboratory network, NRL will train 160 laboratory technicians in good laboratory practices and HIV-related techniques, including CD4 testing, biochemistry, hematology, and HIV and OI diagnosis. This will include two-week trainings for technicians at new ART sites, and two-day refresher trainings for all previously trained lab technicians. These trainings will be carried out by a national team of eight trainer/supervisors placed both centrally and in regional laboratories. As part of its QA activities for TB diagnosis, NRL will also provide refresher training for laboratory technicians in health centers and district hospitals to maintain skill levels in sputum examination for TB by direct AFB smear microscopy.

To ensure quality HIV-related services, this NRL cooperative agreement will continue to fund operational costs (such as specimen transport, supervision costs) associated with the implementation of HIV QA/QC activities in peripheral lab sites, including QA for HIV serology, CD4 testing, chemistry/hematology, and good laboratory practices. Commodities needed to conduct all of the above activities will be procured through the PFSCM activity in FY 2007.